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Items: 42

1.

Inotropic interventions do not change the resting state of myosin motors during cardiac diastole.

Caremani M, Pinzauti F, Powers JD, Governali S, Narayanan T, Stienen GJM, Reconditi M, Linari M, Lombardi V, Piazzesi G.

J Gen Physiol. 2018 Dec 3. pii: jgp.201812196. doi: 10.1085/jgp.201812196. [Epub ahead of print]

PMID:
30510036
2.

Thick Filament Mechano-Sensing in Skeletal and Cardiac Muscles: A Common Mechanism Able to Adapt the Energetic Cost of the Contraction to the Task.

Piazzesi G, Caremani M, Linari M, Reconditi M, Lombardi V.

Front Physiol. 2018 Jun 14;9:736. doi: 10.3389/fphys.2018.00736. eCollection 2018.

3.

The force and stiffness of myosin motors in the isometric twitch of a cardiac trabecula and the effect of the extracellular calcium concentration.

Pinzauti F, Pertici I, Reconditi M, Narayanan T, Stienen GJM, Piazzesi G, Lombardi V, Linari M, Caremani M.

J Physiol. 2018 Jul;596(13):2581-2596. doi: 10.1113/JP275579. Epub 2018 May 27.

PMID:
29714038
4.

Myosin filament activation in the heart is tuned to the mechanical task.

Reconditi M, Caremani M, Pinzauti F, Powers JD, Narayanan T, Stienen GJ, Linari M, Lombardi V, Piazzesi G.

Proc Natl Acad Sci U S A. 2017 Mar 21;114(12):3240-3245. doi: 10.1073/pnas.1619484114. Epub 2017 Mar 6.

5.

Minimum number of myosin motors accounting for shortening velocity under zero load in skeletal muscle.

Fusi L, Percario V, Brunello E, Caremani M, Bianco P, Powers JD, Reconditi M, Lombardi V, Piazzesi G.

J Physiol. 2017 Feb 15;595(4):1127-1142. doi: 10.1113/JP273299. Epub 2016 Dec 12.

6.

Is muscle powered by springs or motors?

Bianco P, Reconditi M, Piazzesi G, Lombardi V.

J Muscle Res Cell Motil. 2016 Oct;37(4-5):165-167. Review. No abstract available.

PMID:
27572873
7.

Size and speed of the working stroke of cardiac myosin in situ.

Caremani M, Pinzauti F, Reconditi M, Piazzesi G, Stienen GJ, Lombardi V, Linari M.

Proc Natl Acad Sci U S A. 2016 Mar 29;113(13):3675-80. doi: 10.1073/pnas.1525057113. Epub 2016 Mar 16.

8.

Force generation by skeletal muscle is controlled by mechanosensing in myosin filaments.

Linari M, Brunello E, Reconditi M, Fusi L, Caremani M, Narayanan T, Piazzesi G, Lombardi V, Irving M.

Nature. 2015 Dec 10;528(7581):276-9. doi: 10.1038/nature15727. Epub 2015 Nov 11.

PMID:
26560032
9.

The contributions of filaments and cross-bridges to sarcomere compliance in skeletal muscle.

Brunello E, Caremani M, Melli L, Linari M, Fernandez-Martinez M, Narayanan T, Irving M, Piazzesi G, Lombardi V, Reconditi M.

J Physiol. 2014 Sep 1;592(17):3881-99. doi: 10.1113/jphysiol.2014.276196. Epub 2014 Jul 11.

10.

The myofilament elasticity and its effect on kinetics of force generation by the myosin motor.

Piazzesi G, Dolfi M, Brunello E, Fusi L, Reconditi M, Bianco P, Linari M, Lombardi V.

Arch Biochem Biophys. 2014 Jun 15;552-553:108-16. doi: 10.1016/j.abb.2014.02.017. Epub 2014 Mar 12.

PMID:
24631572
11.

Sarcomere-length dependence of myosin filament structure in skeletal muscle fibres of the frog.

Reconditi M, Brunello E, Fusi L, Linari M, Martinez MF, Lombardi V, Irving M, Piazzesi G.

J Physiol. 2014 Mar 1;592(5):1119-37. doi: 10.1113/jphysiol.2013.267849. Epub 2013 Dec 16.

12.

The non-linear elasticity of the muscle sarcomere and the compliance of myosin motors.

Fusi L, Brunello E, Reconditi M, Piazzesi G, Lombardi V.

J Physiol. 2014 Mar 1;592(5):1109-18. doi: 10.1113/jphysiol.2013.265983. Epub 2013 Dec 16.

13.

Mechanics of myosin function in white muscle fibres of the dogfish, Scyliorhinus canicula.

Park-Holohan S, Linari M, Reconditi M, Fusi L, Brunello E, Irving M, Dolfi M, Lombardi V, West TG, Curtin NA, Woledge RC, Piazzesi G.

J Physiol. 2012 Apr 15;590(8):1973-88. doi: 10.1113/jphysiol.2011.217133. Epub 2012 Feb 6.

14.

Motion of myosin head domains during activation and force development in skeletal muscle.

Reconditi M, Brunello E, Linari M, Bianco P, Narayanan T, Panine P, Piazzesi G, Lombardi V, Irving M.

Proc Natl Acad Sci U S A. 2011 Apr 26;108(17):7236-40. doi: 10.1073/pnas.1018330108. Epub 2011 Apr 11.

15.

There is no experimental evidence for non-linear myofilament elasticity in skeletal muscle.

Reconditi M.

J Exp Biol. 2010 Feb 15;213(4):658-9; author reply 659. doi: 10.1242/jeb.038067. No abstract available.

16.

The mechanism of the resistance to stretch of isometrically contracting single muscle fibres.

Fusi L, Reconditi M, Linari M, Brunello E, Elangovan R, Lombardi V, Piazzesi G.

J Physiol. 2010 Feb 1;588(Pt 3):495-510. doi: 10.1113/jphysiol.2009.178137. Epub 2009 Nov 30.

17.

Structural changes in myosin motors and filaments during relaxation of skeletal muscle.

Brunello E, Fusi L, Reconditi M, Linari M, Bianco P, Panine P, Narayanan T, Piazzesi G, Lombardi V, Irving M.

J Physiol. 2009 Sep 15;587(Pt 18):4509-21. doi: 10.1113/jphysiol.2009.176222. Epub 2009 Aug 3.

18.

Reverse actin sliding triggers strong myosin binding that moves tropomyosin.

Bekyarova TI, Reedy MC, Baumann BA, Tregear RT, Ward A, Krzic U, Prince KM, Perz-Edwards RJ, Reconditi M, Gore D, Irving TC, Reedy MK.

Proc Natl Acad Sci U S A. 2008 Jul 29;105(30):10372-7. doi: 10.1073/pnas.0709877105. Epub 2008 Jul 25.

19.

Skeletal muscle resists stretch by rapid binding of the second motor domain of myosin to actin.

Brunello E, Reconditi M, Elangovan R, Linari M, Sun YB, Narayanan T, Panine P, Piazzesi G, Irving M, Lombardi V.

Proc Natl Acad Sci U S A. 2007 Dec 11;104(50):20114-9. Epub 2007 Dec 6.

20.

Skeletal muscle performance determined by modulation of number of myosin motors rather than motor force or stroke size.

Piazzesi G, Reconditi M, Linari M, Lucii L, Bianco P, Brunello E, Decostre V, Stewart A, Gore DB, Irving TC, Irving M, Lombardi V.

Cell. 2007 Nov 16;131(4):784-95.

21.
22.

X-ray interference studies of crossbridge action in muscle contraction: evidence from quick releases.

Huxley H, Reconditi M, Stewart A, Irving T.

J Mol Biol. 2006 Nov 3;363(4):743-61. Epub 2006 Sep 1.

PMID:
17007871
23.

Structural changes in the myosin filament and cross-bridges during active force development in single intact frog muscle fibres: stiffness and X-ray diffraction measurements.

Brunello E, Bianco P, Piazzesi G, Linari M, Reconditi M, Panine P, Narayanan T, Helsby WI, Irving M, Lombardi V.

J Physiol. 2006 Dec 15;577(Pt 3):971-84. Epub 2006 Sep 21.

24.

X-ray interference studies of crossbridge action in muscle contraction: evidence from muscles during steady shortening.

Huxley H, Reconditi M, Stewart A, Irving T.

J Mol Biol. 2006 Nov 3;363(4):762-72. Epub 2006 Aug 25. Erratum in: J Mol Biol. 2007 Feb 9;366(1):347.

PMID:
16979661
25.

Distribution of crossbridge states in contracting muscle.

Huxley HE, Reconditi M, Stewart A, Irving T.

Adv Exp Med Biol. 2005;565:37-44; discussion 44, 359-69. No abstract available.

PMID:
16106965
26.

Structure-function relation of the myosin motor in striated muscle.

Reconditi M, Linari M, Lucii L, Stewart A, Sun YB, Narayanan T, Irving T, Piazzesi G, Irving M, Lombardi V.

Ann N Y Acad Sci. 2005 Jun;1047:232-47.

PMID:
16093500
27.

The structural basis of the increase in isometric force production with temperature in frog skeletal muscle.

Linari M, Brunello E, Reconditi M, Sun YB, Panine P, Narayanan T, Piazzesi G, Lombardi V, Irving M.

J Physiol. 2005 Sep 1;567(Pt 2):459-69. Epub 2005 Jun 16.

28.

X-ray diffraction studies of the contractile mechanism in single muscle fibres.

Lombardi V, Piazzesi G, Reconditi M, Linari M, Lucii L, Stewart A, Sun YB, Boesecke P, Narayanan T, Irving T, Irving M.

Philos Trans R Soc Lond B Biol Sci. 2004 Dec 29;359(1452):1883-93. Review.

29.

X-ray interference evidence concerning the range of crossbridge movement, and backbone contributions to the meridional pattern.

Huxley HE, Reconditi M, Stewart A, Irving T.

Adv Exp Med Biol. 2003;538:233-41; discussion 241-2. No abstract available.

PMID:
15098671
30.

The myosin motor in muscle generates a smaller and slower working stroke at higher load.

Reconditi M, Linari M, Lucii L, Stewart A, Sun YB, Boesecke P, Narayanan T, Fischetti RF, Irving T, Piazzesi G, Irving M, Lombardi V.

Nature. 2004 Apr 1;428(6982):578-81.

PMID:
15058307
31.

The mechanism of the force response to stretch in human skinned muscle fibres with different myosin isoforms.

Linari M, Bottinelli R, Pellegrino MA, Reconditi M, Reggiani C, Lombardi V.

J Physiol. 2004 Jan 15;554(Pt 2):335-52. Epub 2003 Oct 10. Erratum in: J Physiol. 2004 Mar 16;555(Pt 3):851.

32.

The conformation of myosin head domains in rigor muscle determined by X-ray interference.

Reconditi M, Koubassova N, Linari M, Dobbie I, Narayanan T, Diat O, Piazzesi G, Lombardi V, Irving M.

Biophys J. 2003 Aug;85(2):1098-110.

33.

Temperature dependence of the force-generating process in single fibres from frog skeletal muscle.

Piazzesi G, Reconditi M, Koubassova N, Decostre V, Linari M, Lucii L, Lombardi V.

J Physiol. 2003 May 15;549(Pt 1):93-106. Epub 2003 Mar 28.

34.

Mechanism of force generation by myosin heads in skeletal muscle.

Piazzesi G, Reconditi M, Linari M, Lucii L, Sun YB, Narayanan T, Boesecke P, Lombardi V, Irving M.

Nature. 2002 Feb 7;415(6872):659-62.

PMID:
11832949
35.

A combined mechanical and X-ray diffraction study of stretch potentiation in single frog muscle fibres.

Linari M, Lucii L, Reconditi M, Casoni ME, Amenitsch H, Bernstorff S, Piazzesi G, Lombardi V.

J Physiol. 2000 Aug 1;526 Pt 3:589-96.

36.

Conformation of the myosin motor during force generation in skeletal muscle.

Irving M, Piazzesi G, Lucii L, Sun YB, Harford JJ, Dobbie IM, Ferenczi MA, Reconditi M, Lombardi V.

Nat Struct Biol. 2000 Jun;7(6):482-5.

PMID:
10881196
37.

Interference fine structure and sarcomere length dependence of the axial x-ray pattern from active single muscle fibers.

Linari M, Piazzesi G, Dobbie I, Koubassova N, Reconditi M, Narayanan T, Diat O, Irving M, Lombardi V.

Proc Natl Acad Sci U S A. 2000 Jun 20;97(13):7226-31.

38.

Myosin head movements during isometric contraction studied by X-ray diffraction of single frog muscle fibres.

Reconditi M, Dobbie I, Irving M, Diat O, Boesecke P, Linari M, Piazzesi G, Lombardi V.

Adv Exp Med Biol. 1998;453:265-70.

PMID:
9889838
39.

Changes in conformation of myosin heads during the development of isometric contraction and rapid shortening in single frog muscle fibres.

Piazzesi G, Reconditi M, Dobbie I, Linari M, Boesecke P, Diat O, Irving M, Lombardi V.

J Physiol. 1999 Jan 15;514 ( Pt 2):305-12.

40.

Elastic bending and active tilting of myosin heads during muscle contraction.

Dobbie I, Linari M, Piazzesi G, Reconditi M, Koubassova N, Ferenczi MA, Lombardi V, Irving M.

Nature. 1998 Nov 26;396(6709):383-7.

PMID:
9845077
41.

The stiffness of skeletal muscle in isometric contraction and rigor: the fraction of myosin heads bound to actin.

Linari M, Dobbie I, Reconditi M, Koubassova N, Irving M, Piazzesi G, Lombardi V.

Biophys J. 1998 May;74(5):2459-73.

42.

Cross-bridge detachment and attachment following a step stretch imposed on active single frog muscle fibres.

Piazzesi G, Linari M, Reconditi M, Vanzi F, Lombardi V.

J Physiol. 1997 Jan 1;498 ( Pt 1):3-15.

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