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Items: 1 to 50 of 172

1.

Cost-effective Tapering Algorithm in Rheumatoid Arthritis Patients: Combination of Multibiomarker Disease Activity Score and Autoantibody Status.

Hagen M, Englbrecht M, Haschka J, Reiser M, Kleyer A, Hueber A, Manger B, Figueiredo C, Fogagnolo Cobra J, Tony HP, Finzel S, Kleinert S, Wendler J, Schuch F, Ronneberger M, Feuchtenberger M, Fleck M, Manger K, Ochs W, Lorenz HM, Nüsslein H, Alten R, Henes J, Krüger K, Schett G, Rech J.

J Rheumatol. 2018 Dec 1. pii: jrheum.180028. doi: 10.3899/jrheum.180028. [Epub ahead of print]

PMID:
30504510
2.

A conserved mechanism drives partition complex assembly on bacterial chromosomes and plasmids.

Debaugny RE, Sanchez A, Rech J, Labourdette D, Dorignac J, Geniet F, Palmeri J, Parmeggiani A, Boudsocq F, Anton Leberre V, Walter JC, Bouet JY.

Mol Syst Biol. 2018 Nov 16;14(11):e8516. doi: 10.15252/msb.20188516.

3.

Sensitivity and specifity of autoantibodies against CD74 in axial spondyloarthritis.

Riechers E, Baerlecken N, Baraliakos X, Achilles-Mehr Bakhsh K, Aries P, Bannert B, Becker K, Brandt-Jürgens J, Braun J, Ehrenstein B, Euler HH, Fleck M, Hein R, Karberg K, Köhler L, Matthias T, Max R, Melzer A, Meyer-Olson D, Rech J, Rockwitz K, Rudwaleit M, Schmidt RE, Schweikhard E, Sieper J, Stille C, von Hinüber U, Wagener P, Weidemann HF, Zinke S, Witte T.

Arthritis Rheumatol. 2018 Nov 12. doi: 10.1002/art.40777. [Epub ahead of print]

PMID:
30418704
4.

Update on imaging in gout: contrasting and comparing the role of dual-energy computed tomography to traditional diagnostic and monitoring techniques.

Bayat S, Baraf HSB, Rech J.

Clin Exp Rheumatol. 2018 Sep-Oct;36 Suppl 114(5):53-60. Epub 2018 Oct 1. Review.

5.

Simultaneous quantification of bone erosions and enthesiophytes in the joints of patients with psoriasis or psoriatic arthritis - effects of age and disease duration.

Simon D, Kleyer A, Faustini F, Englbrecht M, Haschka J, Berlin A, Kraus S, Hueber AJ, Kocijan R, Sticherling M, Rech J, Schett G.

Arthritis Res Ther. 2018 Aug 31;20(1):203. doi: 10.1186/s13075-018-1691-z.

6.

Secukinumab in the treatment of psoriatic arthritis: efficacy and safety results through 3 years from the year 1 extension of the randomised phase III FUTURE 1 trial.

Mease PJ, Kavanaugh A, Reimold A, Tahir H, Rech J, Hall S, Geusens P, Pellet P, Delicha EM, Mpofu S, Pricop L.

RMD Open. 2018 Aug 13;4(2):e000723. doi: 10.1136/rmdopen-2018-000723. eCollection 2018. Erratum in: RMD Open. 2018 Sep 7;4(2):e000723corr1.

7.

Cortical bone loss is an early feature of nonradiographic axial spondyloarthritis.

Neumann A, Haschka J, Kleyer A, Schuster L, Englbrecht M, Berlin A, Figueiredo CP, Simon D, Muschitz C, Kocijan R, Resch H, Rech J, Schett G.

Arthritis Res Ther. 2018 Aug 30;20(1):202. doi: 10.1186/s13075-018-1620-1.

8.

Resolution of synovitis and arrest of catabolic and anabolic bone changes in patients with psoriatic arthritis by IL-17A blockade with secukinumab: results from the prospective PSARTROS study.

Kampylafka E, d'Oliveira I, Linz C, Lerchen V, Stemmler F, Simon D, Englbrecht M, Sticherling M, Rech J, Kleyer A, Schett G, Hueber AJ.

Arthritis Res Ther. 2018 Jul 27;20(1):153. doi: 10.1186/s13075-018-1653-5.

9.

A comparative analysis of articular bone in large cohort of patients with chronic inflammatory diseases of the joints, the gut and the skin.

Simon D, Kleyer A, Englbrecht M, Stemmler F, Simon C, Berlin A, Kocijan R, Haschka J, Hirschmann S, Atreya R, Neurath MF, Sticherling M, Rech J, Hueber AJ, Engelke K, Schett G.

Bone. 2018 Nov;116:87-93. doi: 10.1016/j.bone.2018.07.017. Epub 2018 Jul 23.

PMID:
30048820
10.

From proteomics to discovery of first-in-class ST2 inhibitors active in vivo.

Ramadan AM, Daguindau E, Rech JC, Chinnaswamy K, Zhang J, Hura GL, Griesenauer B, Bolten Z, Robida A, Larsen M, Stuckey JA, Yang CY, Paczesny S.

JCI Insight. 2018 Jul 25;3(14). pii: 99208. doi: 10.1172/jci.insight.99208. [Epub ahead of print]

11.

Effects of ustekinumab versus tumor necrosis factor inhibition on enthesitis: Results from the enthesial clearance in psoriatic arthritis (ECLIPSA) study.

Araujo EG, Englbrecht M, Hoepken S, Finzel S, Kampylafka E, Kleyer A, Bayat S, Schoenau V, Hueber A, Rech J, Schett G.

Semin Arthritis Rheum. 2018 Jun 13. pii: S0049-0172(18)30150-1. doi: 10.1016/j.semarthrit.2018.05.011. [Epub ahead of print]

PMID:
30037432
12.

Autoantibodies Recognizing Secondary NEcrotic Cells Promote Neutrophilic Phagocytosis and Identify Patients With Systemic Lupus Erythematosus.

Biermann MHC, Boeltz S, Pieterse E, Knopf J, Rech J, Bilyy R, van der Vlag J, Tincani A, Distler JHW, Krönke G, Schett GA, Herrmann M, Muñoz LE.

Front Immunol. 2018 May 7;9:989. doi: 10.3389/fimmu.2018.00989. eCollection 2018.

13.

Glycosylation of random IgG distinguishes seropositive and seronegative rheumatoid arthritis.

Magorivska I, Döncző B, Dumych T, Karmash A, Boichuk M, Hychka K, Mihalj M, Szabó M, Csánky E, Rech J, Guttman A, Vari SG, Bilyy R.

Autoimmunity. 2018 May;51(3):111-117. doi: 10.1080/08916934.2018.1468886. Epub 2018 May 7.

PMID:
29733234
14.

Agonistic Autoantibodies to the β2-Adrenergic Receptor Involved in the Pathogenesis of Open-Angle Glaucoma.

Jünemann A, Hohberger B, Rech J, Sheriff A, Fu Q, Schlötzer-Schrehardt U, Voll RE, Bartel S, Kalbacher H, Hoebeke J, Rejdak R, Horn F, Wallukat G, Kunze R, Herrmann M.

Front Immunol. 2018 Feb 12;9:145. doi: 10.3389/fimmu.2018.00145. eCollection 2018.

15.

Biomechanical properties of bone are impaired in patients with ACPA-positive rheumatoid arthritis and associated with the occurrence of fractures.

Stemmler F, Simon D, Liphardt AM, Englbrecht M, Rech J, Hueber AJ, Engelke K, Schett G, Kleyer A.

Ann Rheum Dis. 2018 Jul;77(7):973-980. doi: 10.1136/annrheumdis-2017-212404. Epub 2018 Feb 23.

16.

Open-label, multicentre, dose-escalating phase II clinical trial on the safety and efficacy of tadekinig alfa (IL-18BP) in adult-onset Still's disease.

Gabay C, Fautrel B, Rech J, Spertini F, Feist E, Kötter I, Hachulla E, Morel J, Schaeverbeke T, Hamidou MA, Martin T, Hellmich B, Lamprecht P, Schulze-Koops H, Courvoisier DS, Sleight A, Schiffrin EJ.

Ann Rheum Dis. 2018 Jun;77(6):840-847. doi: 10.1136/annrheumdis-2017-212608. Epub 2018 Feb 22.

17.

Elevated Serum Lysophosphatidylcholine in Patients with Systemic Lupus Erythematosus Impairs Phagocytosis of Necrotic Cells In Vitro.

Grossmayer GE, Keppeler H, Boeltz S, Janko C, Rech J, Herrmann M, Lauber K, Muñoz LE.

Front Immunol. 2018 Jan 17;8:1876. doi: 10.3389/fimmu.2017.01876. eCollection 2017.

18.

Cutting Edge: Homeostasis of Innate Lymphoid Cells Is Imbalanced in Psoriatic Arthritis.

Soare A, Weber S, Maul L, Rauber S, Gheorghiu AM, Luber M, Houssni I, Kleyer A, von Pickardt G, Gado M, Simon D, Rech J, Schett G, Distler JHW, Ramming A.

J Immunol. 2018 Feb 15;200(4):1249-1254. doi: 10.4049/jimmunol.1700596. Epub 2018 Jan 12.

PMID:
29330320
19.

Abatacept used in combination with non-methotrexate disease-modifying antirheumatic drugs: a descriptive analysis of data from interventional trials and the real-world setting.

Alten R, Burkhardt H, Feist E, Krüger K, Rech J, Rubbert-Roth A, Voll RE, Elbez Y, Rauch C.

Arthritis Res Ther. 2018 Jan 2;20(1):1. doi: 10.1186/s13075-017-1488-5.

20.

Evidence for genetic overlap between adult onset Still's disease and hereditary periodic fever syndromes.

Sighart R, Rech J, Hueber A, Blank N, Löhr S, Reis A, Sticht H, Hüffmeier U.

Rheumatol Int. 2018 Jan;38(1):111-120. doi: 10.1007/s00296-017-3885-0. Epub 2017 Nov 20.

PMID:
29159471
21.

Methods for segmentation of rheumatoid arthritis bone erosions in high-resolution peripheral quantitative computed tomography (HR-pQCT).

Figueiredo CP, Kleyer A, Simon D, Stemmler F, d'Oliveira I, Weissenfels A, Museyko O, Friedberger A, Hueber AJ, Haschka J, Englbrecht M, Pereira RMR, Rech J, Schett G, Engelke K.

Semin Arthritis Rheum. 2018 Apr;47(5):611-618. doi: 10.1016/j.semarthrit.2017.09.011. Epub 2017 Sep 23.

PMID:
29122245
22.

Surfing on Protein Waves: Proteophoresis as a Mechanism for Bacterial Genome Partitioning.

Walter JC, Dorignac J, Lorman V, Rech J, Bouet JY, Nollmann M, Palmeri J, Parmeggiani A, Geniet F.

Phys Rev Lett. 2017 Jul 14;119(2):028101. doi: 10.1103/PhysRevLett.119.028101. Epub 2017 Jul 13.

PMID:
28753349
23.

Trial of Tocilizumab in Giant-Cell Arteritis.

Stone JH, Tuckwell K, Dimonaco S, Klearman M, Aringer M, Blockmans D, Brouwer E, Cid MC, Dasgupta B, Rech J, Salvarani C, Schett G, Schulze-Koops H, Spiera R, Unizony SH, Collinson N.

N Engl J Med. 2017 Jul 27;377(4):317-328. doi: 10.1056/NEJMoa1613849.

PMID:
28745999
24.

Early Changes of the Cortical Micro-Channel System in the Bare Area of the Joints of Patients With Rheumatoid Arthritis.

Werner D, Simon D, Englbrecht M, Stemmler F, Simon C, Berlin A, Haschka J, Renner N, Buder T, Engelke K, Hueber AJ, Rech J, Schett G, Kleyer A.

Arthritis Rheumatol. 2017 Aug;69(8):1580-1587. doi: 10.1002/art.40148. Epub 2017 Jun 26.

25.

Estimation of π-π Electronic Couplings from Current Measurements.

Trasobares J, Rech J, Jonckheere T, Martin T, Aleveque O, Levillain E, Diez-Cabanes V, Olivier Y, Cornil J, Nys JP, Sivakumarasamy R, Smaali K, Leclere P, Fujiwara A, Théron D, Vuillaume D, Clément N.

Nano Lett. 2017 May 10;17(5):3215-3224. doi: 10.1021/acs.nanolett.7b00804. Epub 2017 Apr 4.

PMID:
28358215
26.

Minimal Excitations in the Fractional Quantum Hall Regime.

Rech J, Ferraro D, Jonckheere T, Vannucci L, Sassetti M, Martin T.

Phys Rev Lett. 2017 Feb 17;118(7):076801. doi: 10.1103/PhysRevLett.118.076801. Epub 2017 Feb 13.

PMID:
28256856
27.

Development of three-dimensional prints of arthritic joints for supporting patients' awareness to structural damage.

Kleyer A, Beyer L, Simon C, Stemmler F, Englbrecht M, Beyer C, Rech J, Manger B, Krönke G, Schett G, Hueber AJ.

Arthritis Res Ther. 2017 Feb 10;19(1):34. doi: 10.1186/s13075-017-1234-z.

28.

Effects of DMARDs on citrullinated peptide autoantibody levels in RA patients-A longitudinal analysis.

Wunderlich C, Oliviera I, Figueiredo CP, Rech J, Schett G.

Semin Arthritis Rheum. 2017 Jun;46(6):709-714. doi: 10.1016/j.semarthrit.2016.09.011. Epub 2016 Oct 3.

PMID:
28109618
29.

Newly diagnosed vs. relapsing giant cell arteritis: Baseline data from the GiACTA trial.

Tuckwell K, Collinson N, Dimonaco S, Klearman M, Blockmans D, Brouwer E, Cid MC, Dasgupta B, Rech J, Salvarani C, Unizony SH, Stone JH; GiACTA Investigators.

Semin Arthritis Rheum. 2017 Apr;46(5):657-664. doi: 10.1016/j.semarthrit.2016.11.002. Epub 2016 Nov 15.

PMID:
27998620
30.

Age- and Sex-Dependent Changes of Intra-articular Cortical and Trabecular Bone Structure and the Effects of Rheumatoid Arthritis.

Simon D, Kleyer A, Stemmler F, Simon C, Berlin A, Hueber AJ, Haschka J, Renner N, Figueiredo C, Neuhuber W, Buder T, Englbrecht M, Rech J, Engelke K, Schett G.

J Bone Miner Res. 2017 Apr;32(4):722-730. doi: 10.1002/jbmr.3025. Epub 2016 Nov 18.

31.

Secukinumab for Long-Term Treatment of Psoriatic Arthritis: A Two-Year Followup From a Phase III, Randomized, Double-Blind Placebo-Controlled Study.

Kavanaugh A, Mease PJ, Reimold AM, Tahir H, Rech J, Hall S, Geusens P, Wang Z, Pricop L, Mpofu S; FUTURE-1 Study Group.

Arthritis Care Res (Hoboken). 2017 Mar;69(3):347-355. doi: 10.1002/acr.23111.

32.

Gout mimicking rheumatoid arthritis.

Petsch C, Araujo E, Hueber A, Schett G, Manger B, Rech J.

Semin Arthritis Rheum. 2017 Feb;46(4):e15. doi: 10.1016/j.semarthrit.2016.08.003. Epub 2016 Aug 16. No abstract available.

PMID:
27660106
33.

Elevated serum levels of free interleukin-18 in adult-onset Still's disease.

Girard C, Rech J, Brown M, Allali D, Roux-Lombard P, Spertini F, Schiffrin EJ, Schett G, Manger B, Bas S, Del Val G, Gabay C.

Rheumatology (Oxford). 2016 Dec;55(12):2237-2247. Epub 2016 Sep 10.

PMID:
27616144
34.

The discovery and preclinical characterization of 6-chloro-N-(2-(4,4-difluoropiperidin-1-yl)-2-(2-(trifluoromethyl)pyrimidin-5-yl)ethyl)quinoline-5-carboxamide based P2X7 antagonists.

Rech JC, Bhattacharya A, Branstetter BJ, Love CJ, Leenaerts JE, Cooymans LP, Eckert WA 3rd, Ao H, Wang Q, Chaplan SR, Wickenden AD, Lebsack AD, Breitenbucher JG.

Bioorg Med Chem Lett. 2016 Oct 1;26(19):4781-4784. doi: 10.1016/j.bmcl.2016.08.029. Epub 2016 Aug 20.

PMID:
27595421
35.

Identification of (R)-(2-Chloro-3-(trifluoromethyl)phenyl)(1-(5-fluoropyridin-2-yl)-4-methyl-6,7-dihydro-1H-imidazo[4,5-c]pyridin-5(4H)-yl)methanone (JNJ 54166060), a Small Molecule Antagonist of the P2X7 receptor.

Swanson DM, Savall BM, Coe KJ, Schoetens F, Koudriakova T, Skaptason J, Wall J, Rech J, Deng X, De Angelis M, Everson A, Lord B, Wang Q, Ao H, Scott B, Sepassi K, Lovenberg TW, Carruthers NI, Bhattacharya A, Letavic MA.

J Med Chem. 2016 Sep 22;59(18):8535-48. doi: 10.1021/acs.jmedchem.6b00989. Epub 2016 Sep 8.

PMID:
27548392
36.

The evolution of P2X7 antagonists with a focus on CNS indications.

Rech JC, Bhattacharya A, Letavic MA, Savall BM.

Bioorg Med Chem Lett. 2016 Aug 15;26(16):3838-45. doi: 10.1016/j.bmcl.2016.06.048. Epub 2016 Jun 30. Review.

PMID:
27426304
37.

Bacterial partition complexes segregate within the volume of the nucleoid.

Le Gall A, Cattoni DI, Guilhas B, Mathieu-Demazière C, Oudjedi L, Fiche JB, Rech J, Abrahamsson S, Murray H, Bouet JY, Nollmann M.

Nat Commun. 2016 Jul 5;7:12107. doi: 10.1038/ncomms12107.

38.

High prevalence of tenosynovial inflammation before onset of rheumatoid arthritis and its link to progression to RA-A combined MRI/CT study.

Kleyer A, Krieter M, Oliveira I, Faustini F, Simon D, Kaemmerer N, Cavalcante A, Tabosa T, Rech J, Hueber A, Schett G.

Semin Arthritis Rheum. 2016 Oct;46(2):143-50. doi: 10.1016/j.semarthrit.2016.05.002. Epub 2016 May 18.

PMID:
27342772
39.

Antimodified protein antibody response pattern influences the risk for disease relapse in patients with rheumatoid arthritis tapering disease modifying antirheumatic drugs.

Figueiredo CP, Bang H, Cobra JF, Englbrecht M, Hueber AJ, Haschka J, Manger B, Kleyer A, Reiser M, Finzel S, Tony HP, Kleinert S, Wendler J, Schuch F, Ronneberger M, Feuchtenberger M, Fleck M, Manger K, Ochs W, Schmitt-Haendle M, Lorenz HM, Nuesslein H, Alten R, Henes J, Krueger K, Rech J, Schett G.

Ann Rheum Dis. 2017 Feb;76(2):399-407. doi: 10.1136/annrheumdis-2016-209297. Epub 2016 Jun 20.

PMID:
27323772
40.

Stochastic Self-Assembly of ParB Proteins Builds the Bacterial DNA Segregation Apparatus.

Sanchez A, Cattoni DI, Walter JC, Rech J, Parmeggiani A, Nollmann M, Bouet JY.

Cell Syst. 2015 Aug 26;1(2):163-73. doi: 10.1016/j.cels.2015.07.013. Epub 2015 Aug 26.

41.

Quantification and Impact of Secondary Osteoarthritis in Patients With Anti-Citrullinated Protein Antibody-Positive Rheumatoid Arthritis.

Figueiredo CP, Simon D, Englbrecht M, Haschka J, Kleyer A, Bayat S, Hueber A, Pereira RM, Rech J, Schett G.

Arthritis Rheumatol. 2016 Sep;68(9):2114-21. doi: 10.1002/art.39698.

42.

Subclinical joint inflammation in patients with psoriasis without concomitant psoriatic arthritis: a cross-sectional and longitudinal analysis.

Faustini F, Simon D, Oliveira I, Kleyer A, Haschka J, Englbrecht M, Cavalcante AR, Kraus S, Tabosa TP, Figueiredo C, Hueber AJ, Kocijan R, Cavallaro A, Schett G, Sticherling M, Rech J.

Ann Rheum Dis. 2016 Dec;75(12):2068-2074. doi: 10.1136/annrheumdis-2015-208821. Epub 2016 Feb 25.

PMID:
26916344
43.

High-resolution Quantitative Computed Tomography Demonstrates Structural Defects in Cortical and Trabecular Bone in IBD Patients.

Haschka J, Hirschmann S, Kleyer A, Englbrecht M, Faustini F, Simon D, Figueiredo CP, Schuster L, Muschitz C, Kocijan R, Resch H, Atreya R, Rech J, Neurath MF, Schett G.

J Crohns Colitis. 2016 May;10(5):532-40. doi: 10.1093/ecco-jcc/jjw012. Epub 2016 Jan 27.

44.

P2X7 receptor antagonism reduces the severity of spontaneous seizures in a chronic model of temporal lobe epilepsy.

Amhaoul H, Ali I, Mola M, Van Eetveldt A, Szewczyk K, Missault S, Bielen K, Kumar-Singh S, Rech J, Lord B, Ceusters M, Bhattacharya A, Dedeurwaerdere S.

Neuropharmacology. 2016 Jun;105:175-185. doi: 10.1016/j.neuropharm.2016.01.018. Epub 2016 Jan 15.

PMID:
26775823
45.

Novel Phenyl-Substituted 5,6-Dihydro-[1,2,4]triazolo[4,3-a]pyrazine P2X7 Antagonists with Robust Target Engagement in Rat Brain.

Chrovian CC, Soyode-Johnson A, Ao H, Bacani GM, Carruthers NI, Lord B, Nguyen L, Rech JC, Wang Q, Bhattacharya A, Letavic MA.

ACS Chem Neurosci. 2016 Apr 20;7(4):490-7. doi: 10.1021/acschemneuro.5b00303. Epub 2016 Jan 15.

PMID:
26752113
46.

Prevalence of monosodium urate deposits in a population of rheumatoid arthritis patients with hyperuricemia.

Petsch C, Araujo EG, Englbrecht M, Bayat S, Cavallaro A, Hueber AJ, Lell M, Schett G, Manger B, Rech J.

Semin Arthritis Rheum. 2016 Jun;45(6):663-8. doi: 10.1016/j.semarthrit.2015.11.014. Epub 2015 Dec 2.

PMID:
26743072
47.

Preclinical characterization of substituted 6,7-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-8(5H)-one P2X7 receptor antagonists.

Ameriks MK, Ao H, Carruthers NI, Lord B, Ravula S, Rech JC, Savall BM, Wall JL, Wang Q, Bhattacharya A, Letavic MA.

Bioorg Med Chem Lett. 2016 Jan 15;26(2):257-261. doi: 10.1016/j.bmcl.2015.12.052. Epub 2015 Dec 17.

PMID:
26707399
48.

[Do we still need clinical studies in rheumatology?].

Henkemeier U, Alten R, Bannert B, Baraliakos X, Behrens F, Heldmann F, Kiltz U, Köhm M, König R, Leipe J, Müller-Ladner U, Rech J, Riechers E, Rubbert-Roth A, Schmidt RE, Schulze-Koops H, Specker C, Tausche AK, Wassenberg S, Witt M, Witte T, Zernicke J, Burkhardt H.

Z Rheumatol. 2016 Feb;75(1):4-10. doi: 10.1007/s00393-015-1687-x. German.

PMID:
26680367
49.

Sialylation of anti-histone immunoglobulin G autoantibodies determines their capabilities to participate in the clearance of late apoptotic cells.

Magorivska I, Muñoz LE, Janko C, Dumych T, Rech J, Schett G, Nimmerjahn F, Bilyy R, Herrmann M.

Clin Exp Immunol. 2016 Apr;184(1):110-7. doi: 10.1111/cei.12744. Epub 2016 Jan 27.

50.

Tophus resolution with pegloticase: a prospective dual-energy CT study.

Araujo EG, Bayat S, Petsch C, Englbrecht M, Faustini F, Kleyer A, Hueber AJ, Cavallaro A, Lell M, Dalbeth N, Manger B, Schett G, Rech J.

RMD Open. 2015 Jun 17;1(1):e000075. doi: 10.1136/rmdopen-2015-000075. eCollection 2015.

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