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Items: 47


DNMT3A Loss Drives Enhancer Hypomethylation in FLT3-ITD-Associated Leukemias.

Yang L, Rodriguez B, Mayle A, Park HJ, Lin X, Luo M, Jeong M, Curry CV, Kim SB, Ruau D, Zhang X, Zhou T, Zhou M, Rebel VI, Challen GA, Göttgens B, Lee JS, Rau R, Li W, Goodell MA.

Cancer Cell. 2016 Aug 8;30(2):363-365. doi: 10.1016/j.ccell.2016.07.015. Epub 2016 Aug 8. No abstract available.


Context Matters: Distinct Disease Outcomes as a Result of Crebbp Hemizygosity in Different Mouse Bone Marrow Compartments.

Zhou T, Perez SN, Cheng Z, Kinney MC, Lemieux ME, Scott LM, Rebel VI.

PLoS One. 2016 Jul 18;11(7):e0158649. doi: 10.1371/journal.pone.0158649. eCollection 2016.


A mechanism for 1,4-Benzoquinone-induced genotoxicity.

Son MY, Deng CX, Hoeijmarkers JH, Rebel VI, Hasty P.

Oncotarget. 2016 Jul 19;7(29):46433-46447. doi: 10.18632/oncotarget.10184.


DNMT3A Loss Drives Enhancer Hypomethylation in FLT3-ITD-Associated Leukemias.

Yang L, Rodriguez B, Mayle A, Park HJ, Lin X, Luo M, Jeong M, Curry CV, Kim SB, Ruau D, Zhang X, Zhou T, Zhou M, Rebel VI, Challen GA, Gottgens B, Lee JS, Rau R, Li W, Goodell MA.

Cancer Cell. 2016 Jun 13;29(6):922-934. doi: 10.1016/j.ccell.2016.05.003. Erratum in: Cancer Cell. 2016 Aug 8;30(2):363-365.


Early Detection of Lung Cancer with Meso Tetra (4-Carboxyphenyl) Porphyrin-Labeled Sputum.

Patriquin L, Merrick DT, Hill D, Holcomb RG, Lemieux ME, Bennett G, Karia B, Rebel VI, Bauer T 2nd.

J Thorac Oncol. 2015 Sep;10(9):1311-1318. doi: 10.1097/JTO.0000000000000627.


Revisiting the case for genetically engineered mouse models in human myelodysplastic syndrome research.

Zhou T, Kinney MC, Scott LM, Zinkel SS, Rebel VI.

Blood. 2015 Aug 27;126(9):1057-68. doi: 10.1182/blood-2015-01-624239. Epub 2015 Jun 15. Review.


Potential relationship between inadequate response to DNA damage and development of myelodysplastic syndrome.

Zhou T, Chen P, Gu J, Bishop AJ, Scott LM, Hasty P, Rebel VI.

Int J Mol Sci. 2015 Jan 5;16(1):966-89. doi: 10.3390/ijms16010966. Review.


Dnmt3a loss predisposes murine hematopoietic stem cells to malignant transformation.

Mayle A, Yang L, Rodriguez B, Zhou T, Chang E, Curry CV, Challen GA, Li W, Wheeler D, Rebel VI, Goodell MA.

Blood. 2015 Jan 22;125(4):629-38.


Identifying DNA mutations in purified hematopoietic stem/progenitor cells.

Cheng Z, Zhou T, Merchant A, Prihoda TJ, Wickes BL, Xu G, Walter CA, Rebel VI.

J Vis Exp. 2014 Feb 24;(84):e50752. doi: 10.3791/50752.


Acquired mutations that affect pre-mRNA splicing in hematologic malignancies and solid tumors.

Scott LM, Rebel VI.

J Natl Cancer Inst. 2013 Oct 16;105(20):1540-9. doi: 10.1093/jnci/djt257. Epub 2013 Sep 19. Review.


Myelodysplastic syndrome: an inability to appropriately respond to damaged DNA?

Zhou T, Hasty P, Walter CA, Bishop AJ, Scott LM, Rebel VI.

Exp Hematol. 2013 Aug;41(8):665-74. doi: 10.1016/j.exphem.2013.04.008. Epub 2013 Apr 30. Review.


Defining a genotoxic profile with mouse embryonic stem cells.

Kim TM, Rebel VI, Hasty P.

Exp Biol Med (Maywood). 2013 Mar;238(3):285-93. doi: 10.1177/1535370213480700. Review.


Mammospheres from murine mammary stem cell-enriched basal cells: clonal characteristics and repopulating potential.

Dong Q, Wang D, Bandyopadhyay A, Gao H, Gorena KM, Hildreth K, Rebel VI, Walter CA, Huang C, Sun LZ.

Stem Cell Res. 2013 May;10(3):396-404. doi: 10.1016/j.scr.2013.01.007. Epub 2013 Jan 30.


JAK2 and genomic instability in the myeloproliferative neoplasms: a case of the chicken or the egg?

Scott LM, Rebel VI.

Am J Hematol. 2012 Nov;87(11):1028-36. doi: 10.1002/ajh.23243. Epub 2012 May 28. Review.


Mice heterozygous for CREB binding protein are hypersensitive to γ-radiation and invariably develop myelodysplastic/myeloproliferative neoplasm.

Zimmer SN, Lemieux ME, Karia BP, Day C, Zhou T, Zhou Q, Kung AL, Suresh U, Chen Y, Kinney MC, Bishop AJ, Rebel VI.

Exp Hematol. 2012 Apr;40(4):295-306.e5. doi: 10.1016/j.exphem.2011.12.004. Epub 2011 Dec 20.


Administration of BMP2/7 in utero partially reverses Rubinstein-Taybi syndrome-like skeletal defects induced by Pdk1 or Cbp mutations in mice.

Shim JH, Greenblatt MB, Singh A, Brady N, Hu D, Drapp R, Ogawa W, Kasuga M, Noda T, Yang SH, Lee SK, Rebel VI, Glimcher LH.

J Clin Invest. 2012 Jan;122(1):91-106. doi: 10.1172/JCI59466. Epub 2011 Dec 1. Erratum in: J Clin Invest. 2012 May 1;122(5):1948.


Meox2Cre-mediated disruption of CSF-1 leads to osteopetrosis and osteocyte defects.

Harris SE, MacDougall M, Horn D, Woodruff K, Zimmer SN, Rebel VI, Fajardo R, Feng JQ, Gluhak-Heinrich J, Harris MA, Abboud Werner S.

Bone. 2012 Jan;50(1):42-53. doi: 10.1016/j.bone.2011.09.038. Epub 2011 Sep 20.


Inactivation of a single copy of Crebbp selectively alters pre-mRNA processing in mouse hematopoietic stem cells.

Lemieux ME, Cheng Z, Zhou Q, White R, Cornell J, Kung AL, Rebel VI.

PLoS One. 2011;6(8):e24153. doi: 10.1371/journal.pone.0024153. Epub 2011 Aug 25.


Crebbp haploinsufficiency in mice alters the bone marrow microenvironment, leading to loss of stem cells and excessive myelopoiesis.

Zimmer SN, Zhou Q, Zhou T, Cheng Z, Abboud-Werner SL, Horn D, Lecocke M, White R, Krivtsov AV, Armstrong SA, Kung AL, Livingston DM, Rebel VI.

Blood. 2011 Jul 7;118(1):69-79. doi: 10.1182/blood-2010-09-307942. Epub 2011 May 9.


Multilocus association of genetic variants in MLL, CREBBP, EP300, and TOP2A with childhood acute lymphoblastic leukemia in Hispanics from Texas.

Piwkham D, Gelfond JA, Rerkamnuaychoke B, Pakakasama S, Rebel VI, Pollock BH, Winick NJ, Collier AB 3rd, Tomlinson GE, Beuten J.

Cancer Epidemiol Biomarkers Prev. 2011 Jun;20(6):1204-12. doi: 10.1158/1055-9965.EPI-11-0059. Epub 2011 Apr 14.


Microarray-based analysis of cell-cycle gene expression during spermatogenesis in the mouse.

Roy Choudhury D, Small C, Wang Y, Mueller PR, Rebel VI, Griswold MD, McCarrey JR.

Biol Reprod. 2010 Oct;83(4):663-75. doi: 10.1095/biolreprod.110.084889. Epub 2010 Jul 14.


Systematic in vivo structure-function analysis of p300 in hematopoiesis.

Kimbrel EA, Lemieux ME, Xia X, Davis TN, Rebel VI, Kung AL.

Blood. 2009 Nov 26;114(23):4804-12. doi: 10.1182/blood-2009-04-217794. Epub 2009 Oct 12.


Identifying genes differentially expressed between PGCs and ES cells reveals a role for CREB-binding protein in germ cell survival.

Elliott AM, de Miguel MP, Rebel VI, Donovan PJ.

Dev Biol. 2007 Nov 15;311(2):347-58. Epub 2007 Aug 22.


Essential role for cyclin D3 in granulocyte colony-stimulating factor-driven expansion of neutrophil granulocytes.

Sicinska E, Lee YM, Gits J, Shigematsu H, Yu Q, Rebel VI, Geng Y, Marshall CJ, Akashi K, Dorfman DM, Touw IP, Sicinski P.

Mol Cell Biol. 2006 Nov;26(21):8052-60. Epub 2006 Sep 5.


Extensive diversity of Ig-superfamily proteins in the immune system of insects.

Watson FL, Püttmann-Holgado R, Thomas F, Lamar DL, Hughes M, Kondo M, Rebel VI, Schmucker D.

Science. 2005 Sep 16;309(5742):1874-8. Epub 2005 Aug 18.


Mouse development and cell proliferation in the absence of D-cyclins.

Kozar K, Ciemerych MA, Rebel VI, Shigematsu H, Zagozdzon A, Sicinska E, Geng Y, Yu Q, Bhattacharya S, Bronson RT, Akashi K, Sicinski P.

Cell. 2004 Aug 20;118(4):477-91.


Distinct roles for CREB-binding protein and p300 in hematopoietic stem cell self-renewal.

Rebel VI, Kung AL, Tanner EA, Yang H, Bronson RT, Livingston DM.

Proc Natl Acad Sci U S A. 2002 Nov 12;99(23):14789-94. Epub 2002 Oct 23.


Role of macrophage-expressed adipocyte fatty acid binding protein in the development of accelerated atherosclerosis in hypercholesterolemic mice.

Layne MD, Patel A, Chen YH, Rebel VI, Carvajal IM, Pellacani A, Ith B, Zhao D, Schreiber BM, Yet SF, Lee ME, Storch J, Perrella MA.

FASEB J. 2001 Dec;15(14):2733-5. Epub 2001 Oct 15.


Absence of mitochondrial superoxide dismutase results in a murine hemolytic anemia responsive to therapy with a catalytic antioxidant.

Friedman JS, Rebel VI, Derby R, Bell K, Huang TT, Kuypers FA, Epstein CJ, Burakoff SJ.

J Exp Med. 2001 Apr 16;193(8):925-34.


Maturation and lineage-specific expression of the coxsackie and adenovirus receptor in hematopoietic cells.

Rebel VI, Hartnett S, Denham J, Chan M, Finberg R, Sieff CA.

Stem Cells. 2000;18(3):176-82.


Gene dose-dependent control of hematopoiesis and hematologic tumor suppression by CBP.

Kung AL, Rebel VI, Bronson RT, Ch'ng LE, Sieff CA, Livingston DM, Yao TP.

Genes Dev. 2000 Feb 1;14(3):272-7.


The p55 TNF-alpha receptor plays a critical role in T cell alloreactivity.

Hill GR, Teshima T, Rebel VI, Krijanovski OI, Cooke KR, Brinson YS, Ferrara JL.

J Immunol. 2000 Jan 15;164(2):656-63.


Essential role for the p55 tumor necrosis factor receptor in regulating hematopoiesis at a stem cell level.

Rebel VI, Hartnett S, Hill GR, Lazo-Kallanian SB, Ferrara JL, Sieff CA.

J Exp Med. 1999 Nov 15;190(10):1493-504.


A comparison of long-term repopulating hematopoietic stem cells in fetal liver and adult bone marrow from the mouse.

Rebel VI, Miller CL, Thornbury GR, Dragowska WH, Eaves CJ, Lansdorp PM.

Exp Hematol. 1996 Apr;24(5):638-48.


Studies of W mutant mice provide evidence for alternate mechanisms capable of activating hematopoietic stem cells.

Miller CL, Rebel VI, Lemieux ME, Helgason CD, Lansdorp PM, Eaves CJ.

Exp Hematol. 1996 Feb;24(2):185-94.


Nonlinear effects of radiation dose on donor-cell reconstitution by limited numbers of purified stem cells.

Rebel VI, Miller CL, Spinelli JJ, Thomas TE, Eaves CJ, Lansdorp PM.

Biol Blood Marrow Transplant. 1995 Nov;1(1):32-9.


Monocytic differentiation induction of HL-60 cells by MC 903, a novel vitamin D analogue.

Rebel VI, Ossenkoppele GJ, van de Loosdrecht AA, Wijermans PW, Beelen RH, Langenhuijsen MM.

Leuk Res. 1992;16(5):443-51.


Coexistence of myelofibrosis and focal osteolysis with clusters of megakaryocytes and necrosis in a patient with trilineage myelodysplastic syndrome.

Rebel VI, Huijgens PC, Wijermans PW, van der Valk P, Langenhuijsen MM.

Eur J Haematol. 1991 Aug;47(2):155-7. No abstract available.


Combined procoagulant activity and proteolytic activity of acute promyelocytic leukemic cells: reversal of the bleeding disorder by cell differentiation.

Wijermans PW, Rebel VI, Ossenkoppele GJ, Huijgens PC, Langenhuijsen MM.

Blood. 1989 Feb 15;73(3):800-5.


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