Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 424


Neisseria meningitidis and meningococcal disease: recent discoveries and innovations.

Read RC.

Curr Opin Infect Dis. 2019 Sep 24. doi: 10.1097/QCO.0000000000000606. [Epub ahead of print]


Controlled human infection with Bordetella pertussis induces asymptomatic, immunising colonisation.

de Graaf H, Ibrahim M, Hill AR, Gbesemete D, Vaughan AT, Gorringe A, Preston A, Buisman AM, Faust SN, Kester KE, Berbers GAM, Diavatopoulos DA, Read RC.

Clin Infect Dis. 2019 Sep 28. pii: ciz840. doi: 10.1093/cid/ciz840. [Epub ahead of print]


The nonpathogenic commensal Neisseria: friends and foes in infectious disease.

Dorey RB, Theodosiou AA, Read RC, Jones CE.

Curr Opin Infect Dis. 2019 Oct;32(5):490-496. doi: 10.1097/QCO.0000000000000585.


Protocol for a controlled human infection with genetically modified Neisseria lactamica expressing the meningococcal vaccine antigen NadA: a potent new technique for experimental medicine.

Gbesemete D, Laver JR, de Graaf H, Ibrahim M, Vaughan A, Faust S, Gorringe A, Read RC.

BMJ Open. 2019 May 1;9(4):e026544. doi: 10.1136/bmjopen-2018-026544.


Alveolar Macrophage Apoptosis-associated Bacterial Killing Helps Prevent Murine Pneumonia.

Preston JA, Bewley MA, Marriott HM, McGarry Houghton A, Mohasin M, Jubrail J, Morris L, Stephenson YL, Cross S, Greaves DR, Craig RW, van Rooijen N, Bingle CD, Read RC, Mitchell TJ, Whyte MKB, Shapiro SD, Dockrell DH.

Am J Respir Crit Care Med. 2019 Jul 1;200(1):84-97. doi: 10.1164/rccm.201804-0646OC.


Microevolution of Neisseria lactamica during nasopharyngeal colonisation induced by controlled human infection.

Pandey A, Cleary DW, Laver JR, Gorringe A, Deasy AM, Dale AP, Morris PD, Didelot X, Maiden MCJ, Read RC.

Nat Commun. 2018 Nov 12;9(1):4753. doi: 10.1038/s41467-018-07235-5.


Genomes of Escherichia coli bacteraemia isolates originating from urinary tract foci contain more virulence-associated genes than those from non-urinary foci and neutropaenic hosts.

Dale AP, Pandey AK, Hesp RJ, Belogiannis K, Laver JR, Shone CC, Read RC.

J Infect. 2018 Dec;77(6):534-543. doi: 10.1016/j.jinf.2018.10.011. Epub 2018 Nov 2.


Malaria systems immunology: Plasmodium vivax induces tolerance during primary infection through dysregulation of neutrophils and dendritic cells.

Vallejo AF, Read RC, Arevalo-Herrera M, Herrera S, Elliott T, Polak ME.

J Infect. 2018 Nov;77(5):440-447. doi: 10.1016/j.jinf.2018.09.005. Epub 2018 Sep 22.


Summary of the international clinical guidelines for the management of hospital-acquired and ventilator-acquired pneumonia.

Torres A, Niederman MS, Chastre J, Ewig S, Fernandez-Vandellos P, Hanberger H, Kollef M, Li Bassi G, Luna CM, Martin-Loeches I, Paiva JA, Read RC, Rigau D, François Timsit J, Welte T, Wunderink R.

ERJ Open Res. 2018 Jun 26;4(2). pii: 00028-2018. doi: 10.1183/23120541.00028-2018. eCollection 2018 Apr.


Correction to: Neisseria lactamica Y92-1009 complete genome sequence.

Pandey AK, Cleary DW, Laver JR, Maiden MCJ, Didelot X, Gorringe A, Read RC.

Stand Genomic Sci. 2018 Feb 16;13:4. doi: 10.1186/s40793-017-0288-5. eCollection 2018.


HIV gp120 in the Lungs of Antiretroviral Therapy-treated Individuals Impairs Alveolar Macrophage Responses to Pneumococci.

Collini PJ, Bewley MA, Mohasin M, Marriott HM, Miller RF, Geretti AM, Beloukas A, Papadimitropoulos A, Read RC, Noursadeghi M, Dockrell DH.

Am J Respir Crit Care Med. 2018 Jun 15;197(12):1604-1615. doi: 10.1164/rccm.201708-1755OC.


Investigating Bordetella pertussis colonisation and immunity: protocol for an inpatient controlled human infection model.

de Graaf H, Gbesemete D, Gorringe AR, Diavatopoulos DA, Kester KE, Faust SN, Read RC.

BMJ Open. 2017 Oct 11;7(10):e018594. doi: 10.1136/bmjopen-2017-018594.


Neisseria lactamica Y92-1009 complete genome sequence.

Pandey AK, Cleary DW, Laver JR, Maiden MCJ, Didelot X, Gorringe A, Read RC.

Stand Genomic Sci. 2017 Jul 24;12:41. doi: 10.1186/s40793-017-0250-6. eCollection 2017. Erratum in: Stand Genomic Sci. 2018 Feb 16;13:4.


A role for the tetraspanin proteins in Salmonella infection of human macrophages.

Hassuna NA, Monk PN, Ali F, Read RC, Partridge LJ.

J Infect. 2017 Aug;75(2):115-124. doi: 10.1016/j.jinf.2017.06.003. Epub 2017 Jun 8.


A phase III observer-blind randomized, controlled study to evaluate the immune response and the correlation with nasopharyngeal carriage after immunization of university students with a quadrivalent meningococcal ACWY glycoconjugate or serogroup B meningococcal vaccine.

Read RC, Dull P, Bai X, Nolan K, Findlow J, Bazaz R, Kleinschmidt A, McCarthy M, Wang H, Toneatto D, Borrow R.

Vaccine. 2017 Jan 11;35(3):427-434. doi: 10.1016/j.vaccine.2016.11.071. Epub 2016 Nov 29.


Modulation of Human Airway Barrier Functions during Burkholderia thailandensis and Francisella tularensis Infection Running Title: Airway Barrier Functions during Bacterial Infections.

Blume C, David J, Bell RE, Laver JR, Read RC, Clark GC, Davies DE, Swindle EJ.

Pathogens. 2016 Aug 3;5(3). pii: E53. doi: 10.3390/pathogens5030053.


Peptides from Tetraspanin CD9 Are Potent Inhibitors of Staphylococcus Aureus Adherence to Keratinocytes.

Ventress JK, Partridge LJ, Read RC, Cozens D, MacNeil S, Monk PN.

PLoS One. 2016 Jul 28;11(7):e0160387. doi: 10.1371/journal.pone.0160387. eCollection 2016.


Analysis of histone post translational modifications in primary monocyte derived macrophages using reverse phase×reverse phase chromatography in conjunction with porous graphitic carbon stationary phase.

Minshull TC, Cole J, Dockrell DH, Read RC, Dickman MJ.

J Chromatogr A. 2016 Jul 1;1453:43-53. doi: 10.1016/j.chroma.2016.05.025. Epub 2016 May 7.


ESCMID guideline: diagnosis and treatment of acute bacterial meningitis.

van de Beek D, Cabellos C, Dzupova O, Esposito S, Klein M, Kloek AT, Leib SL, Mourvillier B, Ostergaard C, Pagliano P, Pfister HW, Read RC, Sipahi OR, Brouwer MC; ESCMID Study Group for Infections of the Brain (ESGIB).

Clin Microbiol Infect. 2016 May;22 Suppl 3:S37-62. doi: 10.1016/j.cmi.2016.01.007. Epub 2016 Apr 7. No abstract available.


The UK joint specialist societies guideline on the diagnosis and management of acute meningitis and meningococcal sepsis in immunocompetent adults.

McGill F, Heyderman RS, Michael BD, Defres S, Beeching NJ, Borrow R, Glennie L, Gaillemin O, Wyncoll D, Kaczmarski E, Nadel S, Thwaites G, Cohen J, Davies NW, Miller A, Rhodes A, Read RC, Solomon T.

J Infect. 2016 Apr;72(4):405-38. doi: 10.1016/j.jinf.2016.01.007. Epub 2016 Feb 2. Erratum in: J Infect. 2016 Jun;72 (6):768-769.


The environmental deposition of influenza virus from patients infected with influenza A(H1N1)pdm09: Implications for infection prevention and control.

Killingley B, Greatorex J, Digard P, Wise H, Garcia F, Varsani H, Cauchemez S, Enstone JE, Hayward A, Curran MD, Read RC, Lim WS, Nicholson KG, Nguyen-Van-Tam JS.

J Infect Public Health. 2016 May-Jun;9(3):278-88. doi: 10.1016/j.jiph.2015.10.009. Epub 2015 Dec 2.


Inability to sustain intraphagolysosomal killing of Staphylococcus aureus predisposes to bacterial persistence in macrophages.

Jubrail J, Morris P, Bewley MA, Stoneham S, Johnston SA, Foster SJ, Peden AA, Read RC, Marriott HM, Dockrell DH.

Cell Microbiol. 2016 Jan;18(1):80-96. doi: 10.1111/cmi.12485. Epub 2015 Sep 2.


Neisserial Molecular Adaptations to the Nasopharyngeal Niche.

Laver JR, Hughes SE, Read RC.

Adv Microb Physiol. 2015;66:323-55. doi: 10.1016/bs.ampbs.2015.05.001. Epub 2015 May 30. Review.


Nasal Inoculation of the Commensal Neisseria lactamica Inhibits Carriage of Neisseria meningitidis by Young Adults: A Controlled Human Infection Study.

Deasy AM, Guccione E, Dale AP, Andrews N, Evans CM, Bennett JS, Bratcher HB, Maiden MC, Gorringe AR, Read RC.

Clin Infect Dis. 2015 May 15;60(10):1512-20. doi: 10.1093/cid/civ098. Epub 2015 Mar 25.


Neisseria meningitidis serogroup B bivalent factor H binding protein vaccine.

Brendish NJ, Read RC.

Expert Rev Vaccines. 2015 Apr;14(4):493-503. doi: 10.1586/14760584.2015.1015997. Epub 2015 Feb 23.


Pneumolysin activates macrophage lysosomal membrane permeabilization and executes apoptosis by distinct mechanisms without membrane pore formation.

Bewley MA, Naughton M, Preston J, Mitchell A, Holmes A, Marriott HM, Read RC, Mitchell TJ, Whyte MK, Dockrell DH.

MBio. 2014 Oct 7;5(5):e01710-14. doi: 10.1128/mBio.01710-14.


Contact dependent suppression of CD4 T cell activation and proliferation by B cells activated through IgD cross-linking.

Preciado-Llanes L, Wing JB, Foster RA, Carlring J, Lees A, Read RC, Heath AW.

Immunology. 2014 Sep 20. doi: 10.1111/imm.12389. [Epub ahead of print]


Effect of a quadrivalent meningococcal ACWY glycoconjugate or a serogroup B meningococcal vaccine on meningococcal carriage: an observer-blind, phase 3 randomised clinical trial.

Read RC, Baxter D, Chadwick DR, Faust SN, Finn A, Gordon SB, Heath PT, Lewis DJ, Pollard AJ, Turner DP, Bazaz R, Ganguli A, Havelock T, Neal KR, Okike IO, Morales-Aza B, Patel K, Snape MD, Williams J, Gilchrist S, Gray SJ, Maiden MC, Toneatto D, Wang H, McCarthy M, Dull PM, Borrow R.

Lancet. 2014 Dec 13;384(9960):2123-31. doi: 10.1016/S0140-6736(14)60842-4. Epub 2014 Aug 18.


Effect of ethnicity on care pathway and outcomes in patients hospitalized with influenza A(H1N1)pdm09 in the UK.

Nyland GA, McKenzie BC, Myles PR, Semple MG, Lim WS, Openshaw PJ, Read RC, Taylor BL, Brett SJ, McMenamin J, Enstone JE, Bannister B, Nicholson KG, Nguyen-Van-Tam JS.

Epidemiol Infect. 2015 Apr;143(6):1129-38. doi: 10.1017/S0950268814001873. Epub 2014 Aug 1.


MBL2 deficiency is associated with higher genomic bacterial loads during meningococcemia in young children.

Darton TC, Jack DL, Johnson M, Borrow R, Guiver M, Kaczmarski EB, Turner MW, Klein NJ, Read RC.

Clin Microbiol Infect. 2014 Dec;20(12):1337-42. doi: 10.1111/1469-0691.12745. Epub 2014 Dec 18.


Neisseria meningitidis; clones, carriage, and disease.

Read RC.

Clin Microbiol Infect. 2014 May;20(5):391-5. doi: 10.1111/1469-0691.12647. Review.


An evaluation of community assessment tools (CATs) in predicting use of clinical interventions and severe outcomes during the A(H1N1)pdm09 pandemic.

Semple MG, Myles PR, Nicholson KG, Lim WS, Read RC, Taylor BL, Brett SJ, Openshaw PJ, Enstone JE, McMenamin J, Bannister B, Nguyen-Van-Tam JS.

PLoS One. 2013 Sep 19;8(9):e75384. doi: 10.1371/journal.pone.0075384. eCollection 2013.


The alveolar microenvironment of patients infected with human immunodeficiency virus does not modify alveolar macrophage interactions with Streptococcus pneumoniae.

Gordon SB, Jagoe RT, Jarman ER, North JC, Pridmore A, Musaya J, French N, Zijlstra EE, Molyneux ME, Read RC.

Clin Vaccine Immunol. 2013 Jun;20(6):882-91. doi: 10.1128/CVI.00582-12. Epub 2013 Apr 10.


Genetic susceptibility to meningococcal infection.

Dale AP, Read RC.

Expert Rev Anti Infect Ther. 2013 Feb;11(2):187-99. doi: 10.1586/eri.12.161. Review.


Anti-adhesion methods as novel therapeutics for bacterial infections.

Cozens D, Read RC.

Expert Rev Anti Infect Ther. 2012 Dec;10(12):1457-68. doi: 10.1586/eri.12.145. Review.


Adjunctive rifampicin to reduce early mortality from Staphylococcus aureus bacteraemia (ARREST): study protocol for a randomised controlled trial.

Thwaites G, Auckland C, Barlow G, Cunningham R, Davies G, Edgeworth J, Greig J, Hopkins S, Jeyaratnam D, Jenkins N, Llewelyn M, Meisner S, Nsutebu E, Planche T, Read RC, Scarborough M, Soares M, Tilley R, Török ME, Williams J, Wilson P, Wyllie S, Walker AS; United Kingdom Clinical Infection Research Group.

Trials. 2012 Dec 18;13:241. doi: 10.1186/1745-6215-13-241.


Human microbial challenge: the ultimate animal model.

Pollard AJ, Savulescu J, Oxford J, Hill AV, Levine MM, Lewis DJ, Read RC, Graham DY, Sun W, Openshaw P, Gordon SB.

Lancet Infect Dis. 2012 Dec;12(12):903-5. doi: 10.1016/S1473-3099(12)70292-X. No abstract available.


Is Hernia in fact a world journal?

Read RC.

Hernia. 2012 Dec;16(6):615-6. doi: 10.1007/s10029-012-0983-5. Epub 2012 Aug 23. No abstract available.


Differences between asthmatics and nonasthmatics hospitalised with influenza A infection.

Myles P, Nguyen-Van-Tam JS, Semple MG, Brett SJ, Bannister B, Read RC, Taylor BL, McMenamin J, Enstone JE, Nicholson KG, Openshaw PJ, Lim WS; Influenza Clinical Information Network FLU-CIN.

Eur Respir J. 2013 Apr;41(4):824-31. doi: 10.1183/09031936.00015512. Epub 2012 Aug 16.


The comparative clinical course of pregnant and non-pregnant women hospitalised with influenza A(H1N1)pdm09 infection.

Dolan GP, Myles PR, Brett SJ, Enstone JE, Read RC, Openshaw PJ, Semple MG, Lim WS, Taylor BL, McMenamin J, Nicholson KG, Bannister B, Nguyen-Van-Tam JS; Influenza Clinical Information Network (FLU-CIN).

PLoS One. 2012;7(8):e41638. Epub 2012 Aug 3.


Monocytes regulate the mechanism of T-cell death by inducing Fas-mediated apoptosis during bacterial infection.

Daigneault M, De Silva TI, Bewley MA, Preston JA, Marriott HM, Mitchell AM, Mitchell TJ, Read RC, Whyte MK, Dockrell DH.

PLoS Pathog. 2012;8(7):e1002814. doi: 10.1371/journal.ppat.1002814. Epub 2012 Jul 19.


Nitrosothiols in bacterial pathogens and pathogenesis.

Laver JR, McLean S, Bowman LA, Harrison LJ, Read RC, Poole RK.

Antioxid Redox Signal. 2013 Jan 20;18(3):309-22. doi: 10.1089/ars.2012.4767. Epub 2012 Aug 22. Review.


Using the NIHR Comprehensive Clinical Research Network for infectious diseases and microbiology research.

Read RC, Carson G.

J Infect. 2012 Aug;65(2):99-101. doi: 10.1016/j.jinf.2012.05.003. Epub 2012 May 11. No abstract available.


Strategies to increase influenza vaccination rates: outcomes of a nationwide cross-sectional survey of UK general practice.

Dexter LJ, Teare MD, Dexter M, Siriwardena AN, Read RC.

BMJ Open. 2012 May 11;2(3). pii: e000851. doi: 10.1136/bmjopen-2011-000851. Print 2012.


Comparison of CATs, CURB-65 and PMEWS as triage tools in pandemic influenza admissions to UK hospitals: case control analysis using retrospective data.

Myles PR, Nguyen-Van-Tam JS, Lim WS, Nicholson KG, Brett SJ, Enstone JE, McMenamin J, Openshaw PJ, Read RC, Taylor BL, Bannister B, Semple MG.

PLoS One. 2012;7(4):e34428. doi: 10.1371/journal.pone.0034428. Epub 2012 Apr 3.


Predictors of clinical outcome in a national hospitalised cohort across both waves of the influenza A/H1N1 pandemic 2009-2010 in the UK.

Myles PR, Semple MG, Lim WS, Openshaw PJ, Gadd EM, Read RC, Taylor BL, Brett SJ, McMenamin J, Enstone JE, Armstrong C, Bannister B, Nicholson KG, Nguyen-Van-Tam JS; Influenza Clinical Information Network (FLU-CIN).

Thorax. 2012 Aug;67(8):709-17. doi: 10.1136/thoraxjnl-2011-200266. Epub 2012 Mar 10.


Correlation of group C meningococcal conjugate vaccine response with B- and T-lymphocyte activity.

Wing JB, Smart L, Borrow R, Findlow J, Findlow H, Lees A, Foster RA, Carlring J, Read RC, Heath AW.

PLoS One. 2012;7(2):e31160. doi: 10.1371/journal.pone.0031160. Epub 2012 Feb 8. Erratum in: PLoS One. 2012;7(11). doi:10.1371/annotation/45ca0028-74a1-427d-ba95-3dbd2acc6b80. Foster, Rachel A [added] Carlring, Jennifer [added].


Age-related loss of CpG methylation in the tumour necrosis factor promoter.

Gowers IR, Walters K, Kiss-Toth E, Read RC, Duff GW, Wilson AG.

Cytokine. 2011 Dec;56(3):792-7. doi: 10.1016/j.cyto.2011.09.009. Epub 2011 Oct 17.


A functional microsatellite of the macrophage migration inhibitory factor gene associated with meningococcal disease.

Renner P, Roger T, Bochud PY, Sprong T, Sweep FC, Bochud M, Faust SN, Haralambous E, Betts H, Chanson AL, Reymond MK, Mermel E, Erard V, van Deuren M, Read RC, Levin M, Calandra T.

FASEB J. 2012 Feb;26(2):907-16. doi: 10.1096/fj.11-195065. Epub 2011 Oct 11.


Supplemental Content

Support Center