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Upregulation of the chromatin remodeler HELLS is mediated by YAP1 in Sonic Hedgehog Medulloblastoma.

Robinson MH, Maximov V, Lallani S, Farooq H, Taylor MD, Read RD, Kenney AM.

Sci Rep. 2019 Sep 20;9(1):13611. doi: 10.1038/s41598-019-50088-1.


Plasmid distribution among Escherichia coli from livestock and associated wastewater: unraveling factors that shape the presence of genes conferring third-generation cephalosporin resistance.

Tymensen L, Booker CW, Hannon SJ, Cook SR, Jokinen C, Zaheer R, Read R, Boerlin P, McAllister T.

Environ Sci Technol. 2019 Sep 18. doi: 10.1021/acs.est.9b03486. [Epub ahead of print]


An oligomeric state-dependent switch in the ER enzyme FICD regulates AMPylation and deAMPylation of BiP.

Perera LA, Rato C, Yan Y, Neidhardt L, McLaughlin SH, Read RJ, Preissler S, Ron D.

EMBO J. 2019 Sep 18:e102177. doi: 10.15252/embj.2019102177. [Epub ahead of print]


Drosophila melanogaster as a Model System for Human Glioblastomas.

Chen AS, Read RD.

Adv Exp Med Biol. 2019;1167:207-224. doi: 10.1007/978-3-030-23629-8_12. Review.


Comparative diversity of microbiomes and Resistomes in beef feedlots, downstream environments and urban sewage influent.

Zaheer R, Lakin SM, Polo RO, Cook SR, Larney FJ, Morley PS, Booker CW, Hannon SJ, Van Domselaar G, Read RR, McAllister TA.

BMC Microbiol. 2019 Aug 27;19(1):197. doi: 10.1186/s12866-019-1548-x.


Evaluation of template-based modeling in CASP13.

Croll TI, Sammito MD, Kryshtafovych A, Read RJ.

Proteins. 2019 Aug 13. doi: 10.1002/prot.25800. [Epub ahead of print]


Evaluation of model refinement in CASP13.

Read RJ, Sammito MD, Kryshtafovych A, Croll TI.

Proteins. 2019 Jul 31. doi: 10.1002/prot.25794. [Epub ahead of print]


The nonpathogenic commensal Neisseria: friends and foes in infectious disease.

Dorey RB, Theodosiou AA, Read RC, Jones CE.

Curr Opin Infect Dis. 2019 Oct;32(5):490-496. doi: 10.1097/QCO.0000000000000585.


Molecular Diagnosis of Vaginitis: Comparing Quantitative PCR and Microbiome Profiling Approaches to Current Microscopy Scoring.

Lynch T, Peirano G, Lloyd T, Read R, Carter J, Chu A, Shaman JA, Jarvis JP, Diamond E, Ijaz UZ, Church D.

J Clin Microbiol. 2019 Aug 26;57(9). pii: e00300-19. doi: 10.1128/JCM.00300-19. Print 2019 Sep.


Concepts of mental disorders in the United Kingdom: Similarities and differences between the lay public and psychiatrists.

Butlin B, Laws K, Read R, Broome MD, Sharma S.

Int J Soc Psychiatry. 2019 Sep;65(6):507-514. doi: 10.1177/0020764019863084. Epub 2019 Jul 16.


Findable Accessible Interoperable Re-usable (FAIR) diffraction data are coming to protein crystallography.

Helliwell JR, Minor W, Weiss MS, Garman EF, Read RJ, Newman J, van Raaij MJ, Hajdu J, Baker EN.

J Appl Crystallogr. 2019 Apr 30;52(Pt 3):495-497. doi: 10.1107/S1600576719005922. eCollection 2019 Jun 1.


Retrospective review of tertiary and neurosyphilis cases in Alberta, 1973-2017.

Landry T, Smyczek P, Cooper R, Gratrix J, Bertholet L, Read R, Romanowski B, Singh AE.

BMJ Open. 2019 Jun 22;9(6):e025995. doi: 10.1136/bmjopen-2018-025995.


Germline mutations in the transcription factor IKZF5 cause thrombocytopenia.

Lentaigne C, Greene D, Sivapalaratnam S, Favier R, Seyres D, Thys C, Grassi L, Mangles S, Sibson K, Stubbs MJ, Burden F, Bordet JC, Armari-Alla C, Erber W, Farrow S, Gleadall N, Gomez K, Megy K, Papadia S, Penkett CJ, Sims MC, Stefanucci L, Stephens JC, Read RJ, Stirrups KE, Ouwehand WH, Laffan MA, Frontini M, Freson K, Turro E.

Blood. 2019 Jun 19. pii: blood.2019000782. doi: 10.1182/blood.2019000782. [Epub ahead of print]


GWAS and PheWAS of red blood cell components in a Northern Nevadan cohort.

Read RW, Schlauch KA, Elhanan G, Metcalf WJ, Slonim AD, Aweti R, Borkowski R, Grzymski JJ.

PLoS One. 2019 Jun 13;14(6):e0218078. doi: 10.1371/journal.pone.0218078. eCollection 2019.


Findable Accessible Interoperable Re-usable (FAIR) diffraction data are coming to protein crystallography.

Helliwell JR, Minor W, Weiss MS, Garman EF, Read RJ, Newman J, van Raaij MJ, Hajdu J, Baker EN.

IUCrJ. 2019 Apr 30;6(Pt 3):341-343. doi: 10.1107/S2052252519005918. eCollection 2019 May 1.


Findable Accessible Interoperable Re-usable (FAIR) diffraction data are coming to protein crystallography.

Helliwell JR, Minor W, Weiss MS, Garman EF, Read RJ, Newman J, van Raaij MJ, Hajdu J, Baker EN.

Acta Crystallogr D Struct Biol. 2019 May 1;75(Pt 5):455-457. doi: 10.1107/S2059798319004844. Epub 2019 Apr 29. No abstract available.


Protocol for a controlled human infection with genetically modified Neisseria lactamica expressing the meningococcal vaccine antigen NadA: a potent new technique for experimental medicine.

Gbesemete D, Laver JR, de Graaf H, Ibrahim M, Vaughan A, Faust S, Gorringe A, Read RC.

BMJ Open. 2019 May 1;9(4):e026544. doi: 10.1136/bmjopen-2018-026544.


Findable Accessible Interoperable Re-usable (FAIR) diffraction data are coming to protein crystallography.

Helliwell JR, Minor W, Weiss MS, Garman EF, Read RJ, Newman J, van Raaij MJ, Hajdu J, Baker EN.

Acta Crystallogr F Struct Biol Commun. 2019 May 1;75(Pt 5):321-323. doi: 10.1107/S2053230X19005909. Epub 2019 Apr 30. No abstract available.


Addressing sleep problems and fatigue within child and adolescent mental health services: A qualitative study.

Higson-Sweeney N, Loades ME, Hiller R, Read R.

Clin Child Psychol Psychiatry. 2019 Apr 8:1359104519838573. doi: 10.1177/1359104519838573. [Epub ahead of print]


Coping with strong translational noncrystallographic symmetry and extreme anisotropy in molecular replacement with Phaser: human Rab27a.

Jamshidiha M, Pérez-Dorado I, Murray JW, Tate EW, Cota E, Read RJ.

Acta Crystallogr D Struct Biol. 2019 Mar 1;75(Pt 3):342-353. doi: 10.1107/S2059798318017825. Epub 2019 Feb 28.


Early onset of renal oxidative stress in small for gestational age newborn pigs.

Soni H, Yakimkova T, Matthews AT, Amartey PK, Read RW, Buddington RK, Adebiyi A.

Redox Rep. 2019 Dec;24(1):10-16. doi: 10.1080/13510002.2019.1596429.


Prebiotics from acorn and sago prevent high-fat-diet-induced insulin resistance via microbiome-gut-brain axis modulation.

Ahmadi S, Nagpal R, Wang S, Gagliano J, Kitzman DW, Soleimanian-Zad S, Sheikh-Zeinoddin M, Read R, Yadav H.

J Nutr Biochem. 2019 May;67:1-13. doi: 10.1016/j.jnutbio.2019.01.011. Epub 2019 Jan 30.


Resource Concentration Modulates the Fate of Dissimilated Nitrogen in a Dual-Pathway Actinobacterium.

Vuono DC, Read RW, Hemp J, Sullivan BW, Arnone JA 3rd, Neveux I, Blank RR, Loney E, Miceli D, Winkler MH, Chakraborty R, Stahl DA, Grzymski JJ.

Front Microbiol. 2019 Jan 22;10:3. doi: 10.3389/fmicb.2019.00003. eCollection 2019.


Functional screening for triclosan resistance in a wastewater metagenome and isolates of Escherichia coli and Enterococcus spp. from a large Canadian healthcare region.

Cameron A, Barbieri R, Read R, Church D, Adator EH, Zaheer R, McAllister TA.

PLoS One. 2019 Jan 24;14(1):e0211144. doi: 10.1371/journal.pone.0211144. eCollection 2019.


Alveolar Macrophage Apoptosis-associated Bacterial Killing Helps Prevent Murine Pneumonia.

Preston JA, Bewley MA, Marriott HM, McGarry Houghton A, Mohasin M, Jubrail J, Morris L, Stephenson YL, Cross S, Greaves DR, Craig RW, van Rooijen N, Bingle CD, Read RC, Mitchell TJ, Whyte MKB, Shapiro SD, Dockrell DH.

Am J Respir Crit Care Med. 2019 Jul 1;200(1):84-97. doi: 10.1164/rccm.201804-0646OC.


"It's not one size fits all"; the use of videoconferencing for delivering therapy in a Specialist Paediatric Chronic Fatigue Service.

Haig-Ferguson A, Loades M, Whittle C, Read R, Higson-Sweeney N, Beasant L, Starbuck J, Crawley E.

Internet Interv. 2018 Dec 23;15:43-51. doi: 10.1016/j.invent.2018.12.003. eCollection 2019 Mar.


Coordinated downregulation of the photosynthetic apparatus as a protective mechanism against UV exposure in the diatom Corethron hystrix.

Read RW, Vuono DC, Neveux I, Staub C, Grzymski JJ.

Appl Microbiol Biotechnol. 2019 Feb;103(4):1837-1850. doi: 10.1007/s00253-018-9544-x. Epub 2019 Jan 7.


Structural basis for the specificity of renin-mediated angiotensinogen cleavage.

Yan Y, Zhou A, Carrell RW, Read RJ.

J Biol Chem. 2019 Feb 15;294(7):2353-2364. doi: 10.1074/jbc.RA118.006608. Epub 2018 Dec 18.


Drak/STK17A Drives Neoplastic Glial Proliferation through Modulation of MRLC Signaling.

Chen AS, Wardwell-Ozgo J, Shah NN, Wright D, Appin CL, Vigneswaran K, Brat DJ, Kornblum HI, Read RD.

Cancer Res. 2019 Mar 15;79(6):1085-1097. doi: 10.1158/0008-5472.CAN-18-0482. Epub 2018 Dec 10.


ERS syllabus for postgraduate training in respiratory infections: a guide for comprehensive training.

Aliberti S, Farr A, Tabin N, Blasi F, Torres A, Woodhead M, Migliori GB, Sotgiu G, Dimopoulos G, Chalmers JD, Ringshausen FC, Loebinger MR, Read R, Rohde G.

Breathe (Sheff). 2018 Dec;14(4):269-275. doi: 10.1183/20734735.026218.


Measurement of the total angiotensinogen and its reduced and oxidised forms in human plasma using targeted LC-MS/MS.

Dahabiyeh LA, Tooth D, Carrell RW, Read RJ, Yan Y, Pipkin FB, Barrett DA.

Anal Bioanal Chem. 2019 Jan;411(2):427-437. doi: 10.1007/s00216-018-1455-2. Epub 2018 Nov 21.


What does Brexit mean for the UK social care workforce? Perspectives from the recruitment and retention frontline.

Read R, Fenge LA.

Health Soc Care Community. 2019 May;27(3):676-682. doi: 10.1111/hsc.12684. Epub 2018 Nov 19.


Structure and oligomerization of the periplasmic domain of GspL from the type II secretion system of Pseudomonas aeruginosa.

Fulara A, Vandenberghe I, Read RJ, Devreese B, Savvides SN.

Sci Rep. 2018 Nov 13;8(1):16760. doi: 10.1038/s41598-018-34956-w.


Microevolution of Neisseria lactamica during nasopharyngeal colonisation induced by controlled human infection.

Pandey A, Cleary DW, Laver JR, Gorringe A, Deasy AM, Dale AP, Morris PD, Didelot X, Maiden MCJ, Read RC.

Nat Commun. 2018 Nov 12;9(1):4753. doi: 10.1038/s41467-018-07235-5.


Genomes of Escherichia coli bacteraemia isolates originating from urinary tract foci contain more virulence-associated genes than those from non-urinary foci and neutropaenic hosts.

Dale AP, Pandey AK, Hesp RJ, Belogiannis K, Laver JR, Shone CC, Read RC.

J Infect. 2018 Dec;77(6):534-543. doi: 10.1016/j.jinf.2018.10.011. Epub 2018 Nov 2.


Superficial keratectomy as a treatment for non-healing corneal ulceration associated with primary corneal endothelial degeneration.

Bayley KD, Read RA, Gates MC.

Vet Ophthalmol. 2019 Jul;22(4):485-492. doi: 10.1111/vop.12617. Epub 2018 Oct 26.


United Kingdom should learn from global body for biodiversity.

Anderson V, Jones A, Read R.

Nature. 2018 Oct;562(7725):39. doi: 10.1038/d41586-018-06892-2. No abstract available.


Malaria systems immunology: Plasmodium vivax induces tolerance during primary infection through dysregulation of neutrophils and dendritic cells.

Vallejo AF, Read RC, Arevalo-Herrera M, Herrera S, Elliott T, Polak ME.

J Infect. 2018 Nov;77(5):440-447. doi: 10.1016/j.jinf.2018.09.005. Epub 2018 Sep 22.


Au courant computation of the PDB to audit diffraction anisotropy of soluble and membrane proteins.

Robert X, Kassis-Sahyoun J, Ceres N, Martin J, Sawaya MR, Read RJ, Gouet P, Falson P, Chaptal V.

Data Brief. 2018 May 19;19:753-757. doi: 10.1016/j.dib.2018.05.072. eCollection 2018 Aug.


Human-origin probiotic cocktail increases short-chain fatty acid production via modulation of mice and human gut microbiome.

Nagpal R, Wang S, Ahmadi S, Hayes J, Gagliano J, Subashchandrabose S, Kitzman DW, Becton T, Read R, Yadav H.

Sci Rep. 2018 Aug 23;8(1):12649. doi: 10.1038/s41598-018-30114-4.


Gonococcal Conjunctivitis in Adults: Case Report and Retrospective Review of Cases in Alberta, Canada, 2000-2016.

Belga S, Gratrix J, Smyczek P, Bertholet L, Read R, Roelofs K, Singh AE.

Sex Transm Dis. 2019 Jan;46(1):47-51. doi: 10.1097/OLQ.0000000000000897.


Surveillance for Antimicrobial Resistance in Gonorrhea: The Alberta Model, 2012⁻2016.

Gratrix J, Kamruzzaman A, Martin I, Smyczek P, Read R, Bertholet L, Naidu P, Singh AE.

Antibiotics (Basel). 2018 Jul 20;7(3). pii: E63. doi: 10.3390/antibiotics7030063.


A retrospective study of the clinical features of new syphilis infections in an HIV-positive cohort in Alberta, Canada.

Lang R, Read R, Krentz HB, Peng M, Ramazani S, Vu Q, Gill MJ.

BMJ Open. 2018 Jul 10;8(7):e021544. doi: 10.1136/bmjopen-2018-021544.


Summary of the international clinical guidelines for the management of hospital-acquired and ventilator-acquired pneumonia.

Torres A, Niederman MS, Chastre J, Ewig S, Fernandez-Vandellos P, Hanberger H, Kollef M, Li Bassi G, Luna CM, Martin-Loeches I, Paiva JA, Read RC, Rigau D, François Timsit J, Welte T, Wunderink R.

ERJ Open Res. 2018 Jun 26;4(2). pii: 00028-2018. doi: 10.1183/23120541.00028-2018. eCollection 2018 Apr.


Real-space refinement in PHENIX for cryo-EM and crystallography.

Afonine PV, Poon BK, Read RJ, Sobolev OV, Terwilliger TC, Urzhumtsev A, Adams PD.

Acta Crystallogr D Struct Biol. 2018 Jun 1;74(Pt 6):531-544. doi: 10.1107/S2059798318006551. Epub 2018 May 30.


Clonal expansion of environmentally-adapted Escherichia coli contributes to propagation of antibiotic resistance genes in beef cattle feedlots.

Tymensen L, Zaheer R, Cook SR, Amoako KK, Goji N, Read R, Booker CW, Hannon SJ, Neumann N, McAllister TA.

Sci Total Environ. 2018 Oct 1;637-638:657-664. doi: 10.1016/j.scitotenv.2018.05.021. Epub 2018 May 11.


CDK5 Inhibition Resolves PKA/cAMP-Independent Activation of CREB1 Signaling in Glioma Stem Cells.

Mukherjee S, Tucker-Burden C, Kaissi E, Newsam A, Duggireddy H, Chau M, Zhang C, Diwedi B, Rupji M, Seby S, Kowalski J, Kong J, Read R, Brat DJ.

Cell Rep. 2018 May 8;23(6):1651-1664. doi: 10.1016/j.celrep.2018.04.016.


Exploiting distant homologues for phasing through the generation of compact fragments, local fold refinement and partial solution combination.

Millán C, Sammito MD, McCoy AJ, Nascimento AFZ, Petrillo G, Oeffner RD, Domínguez-Gil T, Hermoso JA, Read RJ, Usón I.

Acta Crystallogr D Struct Biol. 2018 Apr 1;74(Pt 4):290-304. doi: 10.1107/S2059798318001365. Epub 2018 Apr 3.


Gyre and gimble: a maximum-likelihood replacement for Patterson correlation refinement.

McCoy AJ, Oeffner RD, Millán C, Sammito M, Usón I, Read RJ.

Acta Crystallogr D Struct Biol. 2018 Apr 1;74(Pt 4):279-289. doi: 10.1107/S2059798318001353. Epub 2018 Apr 3.

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