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Items: 21

1.

Discovery of a class of highly potent Janus Kinase 1/2 (JAK1/2) inhibitors demonstrating effective cell-based blockade of IL-13 signaling.

Zak M, Hanan EJ, Lupardus P, Brown DG, Robinson C, Siu M, Lyssikatos JP, Romero FA, Zhao G, Kellar T, Mendonca R, Ray NC, Goodacre SC, Crackett PH, McLean N, Hurley CA, Yuen PW, Cheng YX, Liu X, Liimatta M, Kohli PB, Nonomiya J, Salmon G, Buckley G, Lloyd J, Gibbons P, Ghilardi N, Kenny JR, Johnson A.

Bioorg Med Chem Lett. 2019 Jun 15;29(12):1522-1531. doi: 10.1016/j.bmcl.2019.04.008. Epub 2019 Apr 4.

PMID:
30981576
2.

Role of Immune Cells and Cytokines for Immune Response in Kala-Azar.

Sarkar SR, Ray NC, Nahar S, Roy S, Aziz MA, Al Amin AM, Paul SK.

Mymensingh Med J. 2018 Oct;27(4):904-911.

PMID:
30487514
3.

Lung-restricted inhibition of Janus kinase 1 is effective in rodent models of asthma.

Dengler HS, Wu X, Peng I, Rinderknecht CH, Kwon Y, Suto E, Kohli PB, Liimatta M, Barrett K, Lloyd J, Cain G, Briggs M, Addo S, Salmon G, Ubhayakar S, Deshmukh G, Shahidi-Latham SK, Quiason-Huynh CM, Jackman J, Liu J, Ray NC, Goodacre SC, Johnson A, McKenzie BS, Lee WP, Zak M, Kenny JR, Ghilardi N.

Sci Transl Med. 2018 Nov 21;10(468). pii: eaao2151. doi: 10.1126/scitranslmed.aao2151.

PMID:
30463918
4.

Clinical Characteristics and Haematological Parameters Associated With Visceral Leishmaniasis in Bangladeshi Individuals.

Sarkar SR, Ray NC, Khan ER, Haque N, Hossain MA, Paul SK, Noiri E, Matsumoto Y, Sanjoba C.

Mymensingh Med J. 2018 Jul;27(3):496-503.

PMID:
30141437
5.

Acute Kidney Injury in Patients with Acute Viral Hepatitis: A Study in a Tertiary Care Hospital.

Rahman MA, Roy DK, Debnath CR, Roy AS, Muqueet MA, Kabir MS, Ahammed SU, Rabbani MG, Asadujjaman M, Hossain MB, Islam MA, Ray NC, Borman GC, Islam MS, Das SK, Khan EH, Ara J.

Mymensingh Med J. 2017 Oct;26(4):790-796.

PMID:
29208866
6.

Acute Kidney Injury is More Common in Acute Haemorrhagic Stroke in Mymensingh Medical College Hospital.

Ray NC, Chowdhury MA, Sarkar SR.

Mymensingh Med J. 2016 Jan;25(1):1-6.

PMID:
26931240
7.

Rotavirus is Predominent Enteropathogen in Acute Childhood Diarrhea in Mymensingh.

Sarkar SR, Hossain MA, Paul SK, Ray NC, Monwar S.

Mymensingh Med J. 2015 Oct;24(4):665-70.

PMID:
26620001
8.

Use of modified blood agar plate for identification of pathogenic campylobacter species at Mymensingh Medical College .

Sarkar SR, Hossain MA, Pual SK, Mahmud MC, Ray NC, Haque N.

Mymensingh Med J. 2014 Oct;23(4):667-71.

PMID:
25481583
9.

Multiplex polymerase chain reaction for detection of Campylobacter from stool specimen.

Sarkar SR, Ray NC, Hossain MA, Paul SK, Sarkar S, Kobayashi N.

Mymensingh Med J. 2014 Jul;23(3):449-55.

PMID:
25178595
10.

Culture of pathogenic campylobacter species at Mymensingh Medical College.

Sarkar SR, Hossain MA, Paul SK, Mahmud MC, Ahmed S, Ray NC, Hoque SM, Haq JA, Yasmin T.

Mymensingh Med J. 2014 Apr;23(2):208-12.

PMID:
24858144
11.

Campylobacteriosis - an overview.

Sarkar SR, Hossain MA, Paul SK, Ray NC, Sultana S, Rahman MM, Islam A.

Mymensingh Med J. 2014 Jan;23(1):173-80. Review.

PMID:
24584395
12.

The design of a novel series of muscarinic receptor antagonists leading to AZD8683, a potential inhaled treatment for COPD.

Mete A, Bowers K, Bull RJ, Coope H, Donald DK, Escott KJ, Ford R, Grime K, Mather A, Ray NC, Russell V.

Bioorg Med Chem Lett. 2013 Dec 1;23(23):6248-53. doi: 10.1016/j.bmcl.2013.09.092. Epub 2013 Oct 4.

PMID:
24144851
13.

Discovery of a novel non-steroidal GR antagonist with in vivo efficacy in the olanzapine-induced weight gain model in the rat.

Hunt HJ, Ray NC, Hynd G, Sutton J, Sajad M, O'Connor E, Ahmed S, Lockey P, Daly S, Buckley G, Clark RD, Roe R, Blasey C, Belanoff J.

Bioorg Med Chem Lett. 2012 Dec 15;22(24):7376-80. doi: 10.1016/j.bmcl.2012.10.074. Epub 2012 Oct 23.

PMID:
23131342
14.

Quantitative, architectural analysis of immune cell subsets in tumor-draining lymph nodes from breast cancer patients and healthy lymph nodes.

Setiadi AF, Ray NC, Kohrt HE, Kapelner A, Carcamo-Cavazos V, Levic EB, Yadegarynia S, van der Loos CM, Schwartz EJ, Holmes S, Lee PP.

PLoS One. 2010 Aug 25;5(8):e12420. doi: 10.1371/journal.pone.0012420.

15.

Muscarinic antagonist-beta-adrenergic agonist dual pharmacology molecules as bronchodilators: a patent review.

Ray NC, Alcaraz L.

Expert Opin Ther Pat. 2009 Jan;19(1):1-12. doi: 10.1517/13543770802630331. Review.

PMID:
19441894
16.

1H-Pyrazolo[3,4-g]hexahydro-isoquinolines as selective glucocorticoid receptor antagonists with high functional activity.

Clark RD, Ray NC, Williams K, Blaney P, Ward S, Crackett PH, Hurley C, Dyke HJ, Clark DE, Lockey P, Devos R, Wong M, Porres SS, Bright CP, Jenkins RE, Belanoff J.

Bioorg Med Chem Lett. 2008 Feb 15;18(4):1312-7. doi: 10.1016/j.bmcl.2008.01.027. Epub 2008 Jan 11.

PMID:
18226897
17.

2-Benzenesulfonyl-8a-benzyl-hexahydro-2H-isoquinolin-6-ones as selective glucocorticoid receptor antagonists.

Clark RD, Ray NC, Blaney P, Crackett PH, Hurley C, Williams K, Dyke HJ, Clark DE, Lockey PM, Devos R, Wong M, White A, Belanoff JK.

Bioorg Med Chem Lett. 2007 Oct 15;17(20):5704-8. Epub 2007 Aug 19.

PMID:
17822897
18.

Discovery and optimization of novel, non-steroidal glucocorticoid receptor modulators.

Ray NC, Clark RD, Clark DE, Williams K, Hickin HG, Crackett PH, Dyke HJ, Lockey PM, Wong M, Devos R, White A, Belanoff JK.

Bioorg Med Chem Lett. 2007 Sep 1;17(17):4901-5. Epub 2007 Jun 13.

PMID:
17587578
19.

Novel 7-methoxy-6-oxazol-5-yl-2,3-dihydro-1H-quinazolin-4-ones as IMPDH inhibitors.

Birch HL, Buckley GM, Davies N, Dyke HJ, Frost EJ, Gilbert PJ, Hannah DR, Haughan AF, Madigan MJ, Morgan T, Pitt WR, Ratcliffe AJ, Ray NC, Richard MD, Sharpe A, Taylor AJ, Whitworth JM, Williams SC.

Bioorg Med Chem Lett. 2005 Dec 1;15(23):5335-9. Epub 2005 Oct 3.

PMID:
16202581
20.

Quinazolinethiones and quinazolinediones, novel inhibitors of inosine monophosphate dehydrogenase: synthesis and initial structure-activity relationships.

Buckley GM, Davies N, Dyke HJ, Gilbert PJ, Hannah DR, Haughan AF, Hunt CA, Pitt WR, Profit RH, Ray NC, Richard MD, Sharpe A, Taylor AJ, Whitworth JM, Williams SC.

Bioorg Med Chem Lett. 2005 Feb 1;15(3):751-4.

PMID:
15664851
21.

A solid-phase route to N-cyanoamides.

Morgan T, Ray NC, Parry DM.

Org Lett. 2002 Feb 21;4(4):597-8.

PMID:
11843600

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