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Safety and Efficacy of Mitapivat in Pyruvate Kinase Deficiency.

Grace RF, Rose C, Layton DM, Galactéros F, Barcellini W, Morton DH, van Beers EJ, Yaish H, Ravindranath Y, Kuo KHM, Sheth S, Kwiatkowski JL, Barbier AJ, Bodie S, Silver B, Hua L, Kung C, Hawkins P, Jouvin MH, Bowden C, Glader B.

N Engl J Med. 2019 Sep 5;381(10):933-944. doi: 10.1056/NEJMoa1902678.


Identification of a novel variant in phosphoglycerate kinase-1 (PGK1) in an African-American child (PGK1 Detroit).

Zaidi AU, Bagla S, Ravindranath Y.

Pediatr Hematol Oncol. 2019 Aug;36(5):302-308. doi: 10.1080/08880018.2019.1639863. Epub 2019 Aug 19.


Mild erythrocytosis as a presenting manifestation of PIEZO1 associated erythrocyte volume disorders.

Knight T, Zaidi AU, Wu S, Gadgeel M, Buck S, Ravindranath Y.

Pediatr Hematol Oncol. 2019 Aug;36(5):317-326. doi: 10.1080/08880018.2019.1637984. Epub 2019 Jul 12.


Peer-assisted learning versus didactic teaching in osteology for first-year Indian undergraduate medical students: a quasi-experimental study.

Anantharaman LT, Ravindranath Y, Dayal S, Shankar N.

Surg Radiol Anat. 2019 May 23. doi: 10.1007/s00276-019-02259-y. [Epub ahead of print]


Effects of targeted remediation in anatomy for first year medical students.

Shankar N, Ravindranath Y, Ravindranath R, Shah H.

Anat Cell Biol. 2019 Mar;52(1):57-68. doi: 10.5115/acb.2019.52.1.57. Epub 2019 Mar 29.


Compound heterozygosity in PKLR gene for a previously unrecognized intronic polymorphism and a rare missense mutation as a novel cause of severe pyruvate kinase deficiency.

Bagla S, Bhambhani K, Gadgeel M, Buck S, Jin JP, Ravindranath Y.

Haematologica. 2019 Sep;104(9):e428-e431. doi: 10.3324/haematol.2018.214692. Epub 2019 Apr 4. No abstract available.


Role of Initiating Supportive Care Preceding Veno-occlusive Disease Diagnosis Following Allogeneic Hematopoietic Stem Cell Transplantation in Children.

Rayner P, Spruit JL, Chu R, Yankelevich M, Henry M, Ravindranath Y, Savaşan S.

J Pediatr Hematol Oncol. 2019 Aug;41(6):e395-e401. doi: 10.1097/MPH.0000000000001455.


Successful Treatment of an Adolescent Male With Severe Refractory Evans Syndrome Using Bortezomib-based Therapy.

Knight T, Ravindranath Y, Callaghan MU.

J Pediatr Hematol Oncol. 2018 Oct 5. doi: 10.1097/MPH.0000000000001325. [Epub ahead of print]


Prevalence and management of iron overload in pyruvate kinase deficiency: report from the Pyruvate Kinase Deficiency Natural History Study.

van Beers EJ, van Straaten S, Morton DH, Barcellini W, Eber SW, Glader B, Yaish HM, Chonat S, Kwiatkowski JL, Rothman JA, Sharma M, Neufeld EJ, Sheth S, Despotovic JM, Kollmar N, Pospíšilová D, Knoll CM, Kuo K, Pastore YD, Thompson AA, Newburger PE, Ravindranath Y, Wang WC, Wlodarski MW, Wang H, Holzhauer S, Breakey VR, Verhovsek M, Kunz J, McNaull MA, Rose MJ, Bradeen HA, Addonizio K, Li A, Al-Sayegh H, London WB, Grace RF.

Haematologica. 2019 Feb;104(2):e51-e53. doi: 10.3324/haematol.2018.196295. Epub 2018 Sep 13. No abstract available.


Acquired Pure Red Cell Aplasia and Acquired Amegakaryocytic Thrombocytopenia Associated With Clonal Expansion of T-Cell Large Granular Lymphocytes in a Patient With Lipopolysaccharide-responsive Beige-like Anchor (LRBA) Protein Deficiency.

Rajpurkar M, Buck S, Lafferty J, Wakeling E, Ravindranath Y, Savaşan S.

J Pediatr Hematol Oncol. 2018 Sep 4. doi: 10.1097/MPH.0000000000001292. [Epub ahead of print]


Anatomical Variations of the Temporomesial Structures in Normal Adult Brain - A Cadaveric Study.

Parmar SK, Pruthi N, Ravindranath R, Ravindranath Y, Somanna S, Philip M.

J Neurosci Rural Pract. 2018 Jul-Sep;9(3):317-325. doi: 10.4103/jnrp.jnrp_73_18.


Can the position of the vertebral artery be predicted on a lateral view X-ray of the craniovertebral junction? A radiological anatomy study.

Pruthi N, Nehete L, Maity T, Dawn R, Ravindranath Y, Ravindranath R, Philips M.

Surg Neurol Int. 2018 Jun 26;9:124. doi: 10.4103/sni.sni_109_18. eCollection 2018.


Treatment of Nonmetastatic Unilateral Retinoblastoma in Children.

Pérez V, Sampor C, Rey G, Parareda-Salles A, Kopp K, Dabezies AP, Dufort G, Zelter M, López JP, Urbieta M, Alcalde-Ruiz E, Catala-Mora J, Suñol M, Ossandon D, Fandiño AC, Croxatto JO, de Dávila MTG, Reaman G, Ravindranath Y, Chantada GL.

JAMA Ophthalmol. 2018 Jul 1;136(7):747-752. doi: 10.1001/jamaophthalmol.2018.1501.


Germline mutations as potential causes of childhood solid tumours: comments on the Norwegian childhood cancer cohort study.

Ravindranath Y, Spector LG.

Br J Cancer. 2018 Apr;118(8):1033-1034. doi: 10.1038/s41416-018-0059-0. Epub 2018 Mar 29.


Clinical spectrum of pyruvate kinase deficiency: data from the Pyruvate Kinase Deficiency Natural History Study.

Grace RF, Bianchi P, van Beers EJ, Eber SW, Glader B, Yaish HM, Despotovic JM, Rothman JA, Sharma M, McNaull MM, Fermo E, Lezon-Geyda K, Morton DH, Neufeld EJ, Chonat S, Kollmar N, Knoll CM, Kuo K, Kwiatkowski JL, Pospíšilová D, Pastore YD, Thompson AA, Newburger PE, Ravindranath Y, Wang WC, Wlodarski MW, Wang H, Holzhauer S, Breakey VR, Kunz J, Sheth S, Rose MJ, Bradeen HA, Neu N, Guo D, Al-Sayegh H, London WB, Gallagher PG, Zanella A, Barcellini W.

Blood. 2018 May 17;131(20):2183-2192. doi: 10.1182/blood-2017-10-810796. Epub 2018 Mar 16.


Favism and Glucose-6-Phosphate Dehydrogenase Deficiency.

Zaidi AU, Callaghan MU, Ravindranath Y.

N Engl J Med. 2018 Mar 15;378(11):1067. doi: 10.1056/NEJMc1801271. No abstract available.


KLF1 E325K-associated Congenital Dyserythropoietic Anemia Type IV: Insights Into the Variable Clinical Severity.

Ravindranath Y, Johnson RM, Goyette G, Buck S, Gadgeel M, Gallagher PG.

J Pediatr Hematol Oncol. 2018 Aug;40(6):e405-e409. doi: 10.1097/MPH.0000000000001056.


Glucose phosphate isomerase (GPI) Tadikonda: Characterization of a novel Pro340Ser mutation.

Zaidi AU, Kedar P, Koduri PR, Goyette GW Jr, Buck S, Paglia DE, Ravindranath Y.

Pediatr Hematol Oncol. 2017 Nov;34(8):449-454. doi: 10.1080/08880018.2017.1383541. Epub 2017 Dec 11.


Changes in Bi-ventricular Function After Hematopoietic Stem Cell Transplant as Assessed by Speckle Tracking Echocardiography.

Covi S, Ravindranath Y, Farooqi A, Savasan S, Chu R, Aggarwal S.

Pediatr Cardiol. 2018 Feb;39(2):365-374. doi: 10.1007/s00246-017-1764-9. Epub 2017 Nov 1.


Analysis of Fetal Palate to Assist Pre-natal Ultrasound.

Shastry A, Ravindranath Y, Ravindranath R.

J Clin Diagn Res. 2016 Oct;10(10):AC10-AC12. Epub 2016 Oct 1.


Cord blood lead level in an urban inner-city hospital.

Chawla S, Elbakoush F, Natarajan G, Dwaihy M, Berry A, Ravindranath Y, Bhambhani K, Narayan SB.

J Neonatal Perinatal Med. 2016 Sep 16;9(3):291-3. doi: 10.3233/NPM-16915131.


Methimazole Induced Total Myeloid Aplasia with Delayed Recovery Despite Granulocyte Colony Stimulating Factor (G-CSF): Marrow Progenitor Recovery Kinetics.

Sarker T, Özgönenel B, Gadgeel M, Buck S, Adhikari A, Ravindranath Y.

Indian J Hematol Blood Transfus. 2016 Jun;32(Suppl 1):214-8. doi: 10.1007/s12288-015-0595-1. Epub 2015 Sep 22.


Morphometric and radiological assessments of dimensions of Axis in dry vertebrae: A study in Indian population.

Sharma RM, Pruthi N, Pandey P, Dawn R, Ravindranath Y, Ravindranath R.

Indian J Orthop. 2015 Nov-Dec;49(6):583-8. doi: 10.4103/0019-5413.168758.


Cardioprotection and Safety of Dexrazoxane in Patients Treated for Newly Diagnosed T-Cell Acute Lymphoblastic Leukemia or Advanced-Stage Lymphoblastic Non-Hodgkin Lymphoma: A Report of the Children's Oncology Group Randomized Trial Pediatric Oncology Group 9404.

Asselin BL, Devidas M, Chen L, Franco VI, Pullen J, Borowitz MJ, Hutchison RE, Ravindranath Y, Armenian SH, Camitta BM, Lipshultz SE.

J Clin Oncol. 2016 Mar 10;34(8):854-62. doi: 10.1200/JCO.2015.60.8851. Epub 2015 Dec 23. Erratum in: J Clin Oncol. 2017 Jun 20;35(18):2100.


Biology of childhood acute lymphoblastic leukemia (ALL) in low/middle-income countries--A case for using age at diagnosis for defining low-risk all.

Ravindranath Y.

Pediatr Blood Cancer. 2015 Oct;62(10):1687-8. doi: 10.1002/pbc.25639. Epub 2015 Jul 1. No abstract available.


Childhood leukemia and cancer. Preface.

Ravindranath Y.

Pediatr Clin North Am. 2015 Feb;62(1):xvii-xviii. doi: 10.1016/j.pcl.2014.10.003. No abstract available.


Down syndrome preleukemia and leukemia.

Maloney KW, Taub JW, Ravindranath Y, Roberts I, Vyas P.

Pediatr Clin North Am. 2015 Feb;62(1):121-37. doi: 10.1016/j.pcl.2014.09.009.


Evolution of modern treatment of childhood acute leukemia and cancer: adventures and battles in the 1970s and 1980s.

Ravindranath Y.

Pediatr Clin North Am. 2015 Feb;62(1):1-10. doi: 10.1016/j.pcl.2014.09.005. Review.


6MP adherence in a multiracial cohort of children with acute lymphoblastic leukemia: a Children's Oncology Group study.

Bhatia S, Landier W, Hageman L, Kim H, Chen Y, Crews KR, Evans WE, Bostrom B, Casillas J, Dickens DS, Maloney KW, Neglia JP, Ravindranath Y, Ritchey AK, Wong FL, Relling MV.

Blood. 2014 Oct 9;124(15):2345-53. doi: 10.1182/blood-2014-01-552166. Epub 2014 May 14.


Acute myeloid leukaemia (AML) with t(6;9)(p23;q34) is associated with poor outcome in childhood AML regardless of FLT3-ITD status: a report from the Children's Oncology Group.

Tarlock K, Alonzo TA, Moraleda PP, Gerbing RB, Raimondi SC, Hirsch BA, Ravindranath Y, Lange B, Woods WG, Gamis AS, Meshinchi S.

Br J Haematol. 2014 Jul;166(2):254-259. doi: 10.1111/bjh.12852. Epub 2014 Mar 25.


Childhood acute lymphoblastic leukemia in the Middle East and neighboring countries: a prospective multi-institutional international collaborative study (CALLME1) by the Middle East Childhood Cancer Alliance (MECCA).

Al-Mulla NA, Chandra P, Khattab M, Madanat F, Vossough P, Torfa E, Al-Lamki Z, Zain G, Muwakkit S, Mahmoud S, Al-Jassmi A, Tuncer M, Al-Mukharraq H, Barsaoui S, Arceci RJ, Howard SC, Kulozik AE, Ravindranath Y, Reaman GH, Farranoush M, AlNasser AA.

Pediatr Blood Cancer. 2014 Aug;61(8):1403-10. doi: 10.1002/pbc.25031. Epub 2014 Mar 20.


Focused screening of a panel of cancer-related genetic polymorphisms reveals new susceptibility loci for pediatric acute lymphoblastic leukemia.

Offenmüller S, Ravindranath Y, Goyette G, Kanakapalli D, Miller KS, Brecht IB, Zolk O.

Pediatr Blood Cancer. 2014 Aug;61(8):1411-5. doi: 10.1002/pbc.25011. Epub 2014 Mar 6.


Computed tomography-based classification of axis vertebra: choice of screw placement.

Pruthi N, Dawn R, Ravindranath Y, Maiti TK, Ravindranath R, Philip M.

Eur Spine J. 2014 May;23(5):1084-91. doi: 10.1007/s00586-014-3240-z. Epub 2014 Feb 23.


Outcome of pediatric patients with acute myeloid leukemia (AML) and -5/5q- abnormalities from five pediatric AML treatment protocols: a report from the Children's Oncology Group.

Johnston DL, Alonzo TA, Gerbing RB, Hirsch B, Heerema NA, Ravindranath Y, Woods WG, Lange BJ, Gamis AS, Raimondi SC.

Pediatr Blood Cancer. 2013 Dec;60(12):2073-8. doi: 10.1002/pbc.24573. Epub 2013 Aug 30.


Development and validation of a single-cell network profiling assay-based classifier to predict response to induction therapy in paediatric patients with de novo acute myeloid leukaemia: a report from the Children's Oncology Group.

Lacayo NJ, Alonzo TA, Gayko U, Rosen DB, Westfall M, Purvis N, Putta S, Louie B, Hackett J, Cohen AC, Cesano A, Gerbing R, Ravindranath Y, Dahl GV, Gamis A, Meshinchi S.

Br J Haematol. 2013 Jul;162(2):250-62. doi: 10.1111/bjh.12370. Epub 2013 May 20.


Myelofibrosis, hepatic extramedullary hematopoiesis and ascites associated with vitamin D deficiency in early infancy.

Henry M, Chitlur M, Rajpurkar M, Mastropietro CW, Poulik J, Ravindranath Y.

J Pediatr Hematol Oncol. 2014 May;36(4):319-21. doi: 10.1097/MPH.0b013e31828e548a.


How many sources should be cultured for the diagnosis of a blood stream infection in children with cancer?

Doganis D, Asmar B, Yankelevich M, Thomas R, Ravindranath Y.

Pediatr Hematol Oncol. 2013 Aug;30(5):416-24. doi: 10.3109/08880018.2013.783892. Epub 2013 Apr 9.


Predictive factors for blood stream infections in children with cancer.

Doganis D, Asmar B, Yankelevich M, Thomas R, Ravindranath Y.

Pediatr Hematol Oncol. 2013 Aug;30(5):403-15. doi: 10.3109/08880018.2013.778379. Epub 2013 Mar 22.


Prognostic features in acute megakaryoblastic leukemia in children without Down syndrome: a report from the AML02 multicenter trial and the Children's Oncology Group Study POG 9421.

O'Brien MM, Cao X, Pounds S, Dahl GV, Raimondi SC, Lacayo NJ, Taub J, Chang M, Weinstein HJ, Ravindranath Y, Inaba H, Campana D, Pui CH, Rubnitz JE.

Leukemia. 2013 Mar;27(3):731-4. doi: 10.1038/leu.2012.223. Epub 2012 Aug 3. No abstract available.


Favorable survival maintained in children who have myeloid leukemia associated with Down syndrome using reduced-dose chemotherapy on Children's Oncology Group trial A2971: a report from the Children's Oncology Group.

Sorrell AD, Alonzo TA, Hilden JM, Gerbing RB, Loew TW, Hathaway L, Barnard D, Taub JW, Ravindranath Y, Smith FO, Arceci RJ, Woods WG, Gamis AS.

Cancer. 2012 Oct 1;118(19):4806-14. doi: 10.1002/cncr.27484. Epub 2012 Mar 5.


Natural history of transient myeloproliferative disorder clinically diagnosed in Down syndrome neonates: a report from the Children's Oncology Group Study A2971.

Gamis AS, Alonzo TA, Gerbing RB, Hilden JM, Sorrell AD, Sharma M, Loew TW, Arceci RJ, Barnard D, Doyle J, Massey G, Perentesis J, Ravindranath Y, Taub J, Smith FO.

Blood. 2011 Dec 22;118(26):6752-9; quiz 6996. doi: 10.1182/blood-2011-04-350017. Epub 2011 Aug 17.


Myelodysplastic syndrome in children: changing definitions from FAB 1976 to WHO 2008 classification systems.

Ravindranath Y.

Pediatr Blood Cancer. 2011 Dec 15;57(7):1098-9. doi: 10.1002/pbc.23256. Epub 2011 Jul 25. No abstract available.


Plasma homocysteine levels, methylene tetrahydrofolate reductase polymorphisms, and the risk of thromboembolism in children.

Nahar A, Sabo C, Chitlur M, Ravindranath Y, Lusher J, Rajpurkar M.

J Pediatr Hematol Oncol. 2011 Jul;33(5):330-3. doi: 10.1097/MPH.0b013e318219324f.


Effect of melatonin on the cytotoxicity of chemotherapeutic drugs in human leukemia cells.

Büyükavci M, Ozdemir O, Buck S, Ravindranath Y, Savaşan S.

In Vivo. 2011 May-Jun;25(3):405-9.


What's up with down syndrome and leukemia-A lot!

Taub JW, Ravindranath Y.

Pediatr Blood Cancer. 2011 Jul 15;57(1):1-3. doi: 10.1002/pbc.23033. Epub 2011 Apr 7. No abstract available.


Compliance in retinoblastoma.

Bakhshi S, Gupta S, Gogia V, Ravindranath Y.

Indian J Pediatr. 2010 May;77(5):535-40. doi: 10.1007/s12098-010-0047-8. Epub 2010 Mar 19.


Phase I study of valspodar (PSC-833) with mitoxantrone and etoposide in refractory and relapsed pediatric acute leukemia: a report from the Children's Oncology Group.

O'Brien MM, Lacayo NJ, Lum BL, Kshirsagar S, Buck S, Ravindranath Y, Bernstein M, Weinstein H, Chang MN, Arceci RJ, Sikic BI, Dahl GV.

Pediatr Blood Cancer. 2010 May;54(5):694-702. doi: 10.1002/pbc.22366.


Prevalence and prognostic significance of KIT mutations in pediatric patients with core binding factor AML enrolled on serial pediatric cooperative trials for de novo AML.

Pollard JA, Alonzo TA, Gerbing RB, Ho PA, Zeng R, Ravindranath Y, Dahl G, Lacayo NJ, Becton D, Chang M, Weinstein HJ, Hirsch B, Raimondi SC, Heerema NA, Woods WG, Lange BJ, Hurwitz C, Arceci RJ, Radich JP, Bernstein ID, Heinrich MC, Meshinchi S.

Blood. 2010 Mar 25;115(12):2372-9. doi: 10.1182/blood-2009-09-241075. Epub 2010 Jan 7.


The effects of disruption of genes for peroxiredoxin-2, glutathione peroxidase-1, and catalase on erythrocyte oxidative metabolism.

Johnson RM, Ho YS, Yu DY, Kuypers FA, Ravindranath Y, Goyette GW.

Free Radic Biol Med. 2010 Feb 15;48(4):519-25. doi: 10.1016/j.freeradbiomed.2009.11.021. Epub 2009 Dec 4.


WT1 expression at diagnosis does not predict survival in pediatric AML: a report from the Children's Oncology Group.

Noronha SA, Farrar JE, Alonzo TA, Gerbing RB, Lacayo NJ, Dahl GV, Ravindranath Y, Arceci RJ, Loeb DM.

Pediatr Blood Cancer. 2009 Dec;53(6):1136-9. doi: 10.1002/pbc.22142.

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