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Items: 14

1.

Chemoproteomics of matrix metalloproteases in a model of cartilage degeneration suggests functional biomarkers associated with posttraumatic osteoarthritis.

Ravindra KC, Ahrens CC, Wang Y, Ramseier JY, Wishnok JS, Griffith LG, Grodzinsky AJ, Tannenbaum SR.

J Biol Chem. 2018 Jul 20;293(29):11459-11469. doi: 10.1074/jbc.M117.818542. Epub 2018 May 23.

PMID:
29794029
2.

Integrated Assessment of Diclofenac Biotransformation, Pharmacokinetics, and Omics-Based Toxicity in a Three-Dimensional Human Liver-Immunocompetent Coculture System.

Sarkar U, Ravindra KC, Large E, Young CL, Rivera-Burgos D, Yu J, Cirit M, Hughes DJ, Wishnok JS, Lauffenburger DA, Griffith LG, Tannenbaum SR.

Drug Metab Dispos. 2017 Jul;45(7):855-866. doi: 10.1124/dmd.116.074005. Epub 2017 Apr 27.

3.

S-nitrosation of proteins relevant to Alzheimer's disease during early stages of neurodegeneration.

Seneviratne U, Nott A, Bhat VB, Ravindra KC, Wishnok JS, Tsai LH, Tannenbaum SR.

Proc Natl Acad Sci U S A. 2016 Apr 12;113(15):4152-7. doi: 10.1073/pnas.1521318113. Epub 2016 Mar 24.

4.

Hydroxyphenylation of Histone Lysines: Post-translational Modification by Quinone Imines.

Ravindra KC, Trudel LJ, Wishnok JS, Wogan GN, Tannenbaum SR, Skipper PL.

ACS Chem Biol. 2016 May 20;11(5):1230-7. doi: 10.1021/acschembio.5b00923. Epub 2016 Feb 18.

5.

Untargeted Proteomics and Systems-Based Mechanistic Investigation of Artesunate in Human Bronchial Epithelial Cells.

Ravindra KC, Ho WE, Cheng C, Godoy LC, Wishnok JS, Ong CN, Wong WS, Wogan GN, Tannenbaum SR.

Chem Res Toxicol. 2015 Oct 19;28(10):1903-13. doi: 10.1021/acs.chemrestox.5b00105. Epub 2015 Sep 21.

6.

Metabolite profiling and pharmacokinetic evaluation of hydrocortisone in a perfused three-dimensional human liver bioreactor.

Sarkar U, Rivera-Burgos D, Large EM, Hughes DJ, Ravindra KC, Dyer RL, Ebrahimkhani MR, Wishnok JS, Griffith LG, Tannenbaum SR.

Drug Metab Dispos. 2015 Jul;43(7):1091-9. doi: 10.1124/dmd.115.063495. Epub 2015 Apr 29.

7.

Epigenetic regulation of inflammatory gene expression in macrophages by selenium.

Narayan V, Ravindra KC, Liao C, Kaushal N, Carlson BA, Prabhu KS.

J Nutr Biochem. 2015 Feb;26(2):138-45. doi: 10.1016/j.jnutbio.2014.09.009. Epub 2014 Oct 24.

8.

Evident stabilization of the clinical profile in HIV/AIDS as evaluated in an open label clinical trial using a polyherbal formulation.

Asokan M, Lone IN, Mukthey AB, Siddhartha P, Mariappa G, Kotehal PK, Satish B, Wilson E, Sahayam S, Velayutham G, Perumal R, Baskaran K, Rengarajan D, Muthusamy R, Philip M, Ravindra KC, Basha JN, Mizar P, Kaur G, Mehra NK, Kundu TK, Subbakrishna DK, Satish KS, Ranga U.

Indian J Med Res. 2013 Jun;137(6):1128-44.

9.

Transimination of quinone imines: a mechanism for embedding exogenous redox activity into the nucleosome.

Ye W, Seneviratne UI, Chao MW, Ravindra KC, Wogan GN, Tannenbaum SR, Skipper PL.

Chem Res Toxicol. 2012 Dec 17;25(12):2627-9. doi: 10.1021/tx3004517. Epub 2012 Dec 3.

10.

Targeting of histone acetyltransferase p300 by cyclopentenone prostaglandin Δ(12)-PGJ(2) through covalent binding to Cys(1438).

Ravindra KC, Narayan V, Lushington GH, Peterson BR, Prabhu KS.

Chem Res Toxicol. 2012 Feb 20;25(2):337-47. doi: 10.1021/tx200383c. Epub 2011 Dec 16.

11.

Δ12-prostaglandin J3, an omega-3 fatty acid-derived metabolite, selectively ablates leukemia stem cells in mice.

Hegde S, Kaushal N, Ravindra KC, Chiaro C, Hafer KT, Gandhi UH, Thompson JT, van den Heuvel JP, Kennett MJ, Hankey P, Paulson RF, Prabhu KS.

Blood. 2011 Dec 22;118(26):6909-19. doi: 10.1182/blood-2010-11-317750. Epub 2011 Oct 3.

12.

Celastrol inhibits Tat-mediated human immunodeficiency virus (HIV) transcription and replication.

Narayan V, Ravindra KC, Chiaro C, Cary D, Aggarwal BB, Henderson AJ, Prabhu KS.

J Mol Biol. 2011 Jul 29;410(5):972-83. doi: 10.1016/j.jmb.2011.04.013.

13.

Selenoprotein-dependent up-regulation of hematopoietic prostaglandin D2 synthase in macrophages is mediated through the activation of peroxisome proliferator-activated receptor (PPAR) gamma.

Gandhi UH, Kaushal N, Ravindra KC, Hegde S, Nelson SM, Narayan V, Vunta H, Paulson RF, Prabhu KS.

J Biol Chem. 2011 Aug 5;286(31):27471-82. doi: 10.1074/jbc.M111.260547. Epub 2011 Jun 13.

14.

Inhibition of lysine acetyltransferase KAT3B/p300 activity by a naturally occurring hydroxynaphthoquinone, plumbagin.

Ravindra KC, Selvi BR, Arif M, Reddy BA, Thanuja GR, Agrawal S, Pradhan SK, Nagashayana N, Dasgupta D, Kundu TK.

J Biol Chem. 2009 Sep 4;284(36):24453-64. doi: 10.1074/jbc.M109.023861. Epub 2009 Jul 1.

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