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Items: 1 to 50 of 162

1.

Living on the Edge: Efferocytosis at the Interface of Homeostasis and Pathology.

Morioka S, Maueröder C, Ravichandran KS.

Immunity. 2019 May 21;50(5):1149-1162. doi: 10.1016/j.immuni.2019.04.018. Review.

PMID:
31117011
2.

A noncanonical role for the engulfment gene ELMO1 in neutrophils that promotes inflammatory arthritis.

Arandjelovic S, Perry JSA, Lucas CD, Penberthy KK, Kim TH, Zhou M, Rosen DA, Chuang TY, Bettina AM, Shankman LS, Cohen AH, Gaultier A, Conrads TP, Kim M, Elliott MR, Ravichandran KS.

Nat Immunol. 2019 Feb;20(2):141-151. doi: 10.1038/s41590-018-0293-x. Epub 2019 Jan 14.

PMID:
30643265
3.

Efferocytosis induces a novel SLC program to promote glucose uptake and lactate release.

Morioka S, Perry JSA, Raymond MH, Medina CB, Zhu Y, Zhao L, Serbulea V, Onengut-Gumuscu S, Leitinger N, Kucenas S, Rathmell JC, Makowski L, Ravichandran KS.

Nature. 2018 Nov;563(7733):714-718. doi: 10.1038/s41586-018-0735-5. Epub 2018 Nov 21.

4.

Macrophages regulate the clearance of living cells by calreticulin.

Krysko DV, Ravichandran KS, Vandenabeele P.

Nat Commun. 2018 Nov 7;9(1):4644. doi: 10.1038/s41467-018-06807-9. No abstract available.

5.

A Single-Agent Dual-Specificity Targeting of FOLR1 and DR5 as an Effective Strategy for Ovarian Cancer.

Shivange G, Urbanek K, Przanowski P, Perry JSA, Jones J, Haggart R, Kostka C, Patki T, Stelow E, Petrova Y, Llaneza D, Mayo M, Ravichandran KS, Landen CN, Bhatnagar S, Tushir-Singh J.

Cancer Cell. 2018 Aug 13;34(2):331-345.e11. doi: 10.1016/j.ccell.2018.07.005.

6.

Predictive Analysis on Behavioural Risk Factor Surveillance System through Ensemble Classifiers and Clusters.

Sekar KR, Easwar M, Manikandan R, Ravichandran KS.

J Natl Med Assoc. 2019 Feb;111(1):103-117. doi: 10.1016/j.jnma.2018.07.001. Epub 2018 Aug 3.

PMID:
30078757
7.

Epithelial and Endothelial Pannexin1 Channels Mediate AKI.

Jankowski J, Perry HM, Medina CB, Huang L, Yao J, Bajwa A, Lorenz UM, Rosin DL, Ravichandran KS, Isakson BE, Okusa MD.

J Am Soc Nephrol. 2018 Jul;29(7):1887-1899. doi: 10.1681/ASN.2017121306. Epub 2018 Jun 4.

PMID:
29866797
8.

Response by Good et al to Letter Regarding Article, "Pannexin-1 Channels as an Unexpected New Target of the Antihypertensive Drug Spironolactone".

Good ME, Chiu YH, Poon IKH, Jaffe IZ, Bayliss DA, Isakson BE, Ravichandran KS.

Circ Res. 2018 May 25;122(11):e88-e89. doi: 10.1161/CIRCRESAHA.118.313080. No abstract available.

9.

Pannexin-1 channels on endothelial cells mediate vascular inflammation during lung ischemia-reperfusion injury.

Sharma AK, Charles EJ, Zhao Y, Narahari AK, Baderdinni PK, Good ME, Lorenz UM, Kron IL, Bayliss DA, Ravichandran KS, Isakson BE, Laubach VE.

Am J Physiol Lung Cell Mol Physiol. 2018 Aug 1;315(2):L301-L312. doi: 10.1152/ajplung.00004.2018. Epub 2018 May 10.

PMID:
29745255
10.

Rethinking Phagocytes: Clues from the Retina and Testes.

Penberthy KK, Lysiak JJ, Ravichandran KS.

Trends Cell Biol. 2018 Apr;28(4):317-327. doi: 10.1016/j.tcb.2018.01.004. Epub 2018 Feb 14. Review.

11.

CD47 Blockade as an Adjuvant Immunotherapy for Resectable Pancreatic Cancer.

Michaels AD, Newhook TE, Adair SJ, Morioka S, Goudreau BJ, Nagdas S, Mullen MG, Persily JB, Bullock TNJ, Slingluff CL Jr, Ravichandran KS, Parsons JT, Bauer TW.

Clin Cancer Res. 2018 Mar 15;24(6):1415-1425. doi: 10.1158/1078-0432.CCR-17-2283. Epub 2017 Dec 29.

12.

Pannexin 1 Channels as an Unexpected New Target of the Anti-Hypertensive Drug Spironolactone.

Good ME, Chiu YH, Poon IKH, Medina CB, Butcher JT, Mendu SK, DeLalio LJ, Lohman AW, Leitinger N, Barrett E, Lorenz UM, Desai BN, Jaffe IZ, Bayliss DA, Isakson BE, Ravichandran KS.

Circ Res. 2018 Feb 16;122(4):606-615. doi: 10.1161/CIRCRESAHA.117.312380. Epub 2017 Dec 13.

13.

Context-dependent compensation among phosphatidylserine-recognition receptors.

Penberthy KK, Rival C, Shankman LS, Raymond MH, Zhang J, Perry JSA, Lee CS, Han CZ, Onengut-Gumuscu S, Palczewski K, Lysiak JJ, Ravichandran KS.

Sci Rep. 2017 Nov 7;7(1):14623. doi: 10.1038/s41598-017-15191-1.

14.

Hematopoietic pannexin 1 function is critical for neuropathic pain.

Weaver JL, Arandjelovic S, Brown G, K Mendu S, S Schappe M, Buckley MW, Chiu YH, Shu S, Kim JK, Chung J, Krupa J, Jevtovic-Todorovic V, Desai BN, Ravichandran KS, Bayliss DA.

Sci Rep. 2017 Feb 14;7:42550. doi: 10.1038/srep42550.

15.

A quantized mechanism for activation of pannexin channels.

Chiu YH, Jin X, Medina CB, Leonhardt SA, Kiessling V, Bennett BC, Shu S, Tamm LK, Yeager M, Ravichandran KS, Bayliss DA.

Nat Commun. 2017 Jan 30;8:14324. doi: 10.1038/ncomms14324.

16.

Embryonic Trogocytosis: Neighborly Nibbling during Development.

Perry JS, Ravichandran KS.

Curr Biol. 2017 Jan 23;27(2):R68-R70. doi: 10.1016/j.cub.2016.11.043.

17.

Adhesion GPCRs as Modulators of Immune Cell Function.

Hamann J, Hsiao CC, Lee CS, Ravichandran KS, Lin HH.

Handb Exp Pharmacol. 2016;234:329-350. Review.

PMID:
27832495
18.

Macrophages redirect phagocytosis by non-professional phagocytes and influence inflammation.

Han CZ, Juncadella IJ, Kinchen JM, Buckley MW, Klibanov AL, Dryden K, Onengut-Gumuscu S, Erdbrügger U, Turner SD, Shim YM, Tung KS, Ravichandran KS.

Nature. 2016 Nov 24;539(7630):570-574. doi: 10.1038/nature20141. Epub 2016 Nov 7.

19.

Clearance of Dying Cells by Phagocytes: Mechanisms and Implications for Disease Pathogenesis.

Fond AM, Ravichandran KS.

Adv Exp Med Biol. 2016;930:25-49. doi: 10.1007/978-3-319-39406-0_2. Review.

PMID:
27558816
20.

The Dynamics of Apoptotic Cell Clearance.

Elliott MR, Ravichandran KS.

Dev Cell. 2016 Jul 25;38(2):147-60. doi: 10.1016/j.devcel.2016.06.029. Review.

21.

'This way please': Apoptotic cells regulate phagocyte migration before and after engulfment.

Ariel A, Ravichandran KS.

Eur J Immunol. 2016 Jul;46(7):1583-6. doi: 10.1002/eji.201646505. Epub 2016 Jun 27.

22.

How Mouse Macrophages Sense What Is Going On.

Ley K, Pramod AB, Croft M, Ravichandran KS, Ting JP.

Front Immunol. 2016 Jun 2;7:204. doi: 10.3389/fimmu.2016.00204. eCollection 2016. Review.

23.

Boosting Apoptotic Cell Clearance by Colonic Epithelial Cells Attenuates Inflammation In Vivo.

Lee CS, Penberthy KK, Wheeler KM, Juncadella IJ, Vandenabeele P, Lysiak JJ, Ravichandran KS.

Immunity. 2016 Apr 19;44(4):807-20. doi: 10.1016/j.immuni.2016.02.005. Epub 2016 Mar 29.

24.

Do not let death do us part: 'find-me' signals in communication between dying cells and the phagocytes.

Medina CB, Ravichandran KS.

Cell Death Differ. 2016 Jun;23(6):979-89. doi: 10.1038/cdd.2016.13. Epub 2016 Feb 19. Review.

25.

Novel Approaches for Diagnosing Melanoma Skin Lesions Through Supervised and Deep Learning Algorithms.

Premaladha J, Ravichandran KS.

J Med Syst. 2016 Apr;40(4):96. doi: 10.1007/s10916-016-0460-2. Epub 2016 Feb 12.

PMID:
26872778
26.

The adhesion GPCR BAI1 mediates macrophage ROS production and microbicidal activity against Gram-negative bacteria.

Billings EA, Lee CS, Owen KA, D'Souza RS, Ravichandran KS, Casanova JE.

Sci Signal. 2016 Feb 2;9(413):ra14. doi: 10.1126/scisignal.aac6250.

27.

Apoptotic cell recognition receptors and scavenger receptors.

Penberthy KK, Ravichandran KS.

Immunol Rev. 2016 Jan;269(1):44-59. doi: 10.1111/imr.12376. Review.

28.

Phagocytosis of apoptotic cells in homeostasis.

Arandjelovic S, Ravichandran KS.

Nat Immunol. 2015 Sep;16(9):907-17. doi: 10.1038/ni.3253. Review.

29.

Pannexin 1 channels regulate leukocyte emigration through the venous endothelium during acute inflammation.

Lohman AW, Leskov IL, Butcher JT, Johnstone SR, Stokes TA, Begandt D, DeLalio LJ, Best AK, Penuela S, Leitinger N, Ravichandran KS, Stokes KY, Isakson BE.

Nat Commun. 2015 Aug 5;6:7965. doi: 10.1038/ncomms8965.

30.

Apoptotic cells trigger a membrane-initiated pathway to increase ABCA1.

Fond AM, Lee CS, Schulman IG, Kiss RS, Ravichandran KS.

J Clin Invest. 2015 Jul 1;125(7):2748-58. doi: 10.1172/JCI80300. Epub 2015 Jun 15.

31.

A novel mechanism of generating extracellular vesicles during apoptosis via a beads-on-a-string membrane structure.

Atkin-Smith GK, Tixeira R, Paone S, Mathivanan S, Collins C, Liem M, Goodall KJ, Ravichandran KS, Hulett MD, Poon IK.

Nat Commun. 2015 Jun 15;6:7439. doi: 10.1038/ncomms8439.

32.

Using phosphatidylserine exposure on apoptotic cells to stimulate myoblast fusion.

Hochreiter-Hufford AE, Arandjelovic S, Ravichandran KS.

Methods Mol Biol. 2015;1313:141-8. doi: 10.1007/978-1-4939-2703-6_10.

33.

ShcA regulates thymocyte proliferation through specific transcription factors and a c-Abl-dependent signaling axis.

Trampont PC, Zhang L, Giles AJ, Walk SF, Gu JJ, Pendergast AM, Ravichandran KS.

Mol Cell Biol. 2015 Apr;35(8):1462-76. doi: 10.1128/MCB.01084-14. Epub 2015 Feb 17.

34.

A molecular signature in the pannexin1 intracellular loop confers channel activation by the α1 adrenoreceptor in smooth muscle cells.

Billaud M, Chiu YH, Lohman AW, Parpaite T, Butcher JT, Mutchler SM, DeLalio LJ, Artamonov MV, Sandilos JK, Best AK, Somlyo AV, Thompson RJ, Le TH, Ravichandran KS, Bayliss DA, Isakson BE.

Sci Signal. 2015 Feb 17;8(364):ra17. doi: 10.1126/scisignal.2005824.

35.

Cooperation between Noncanonical Ras Network Mutations.

Stites EC, Trampont PC, Haney LB, Walk SF, Ravichandran KS.

Cell Rep. 2015 Feb 10;10(5):840. doi: 10.1016/j.celrep.2015.01.048. Epub 2015 Feb 11. No abstract available.

36.

Cooperation between Noncanonical Ras Network Mutations.

Stites EC, Trampont PC, Haney LB, Walk SF, Ravichandran KS.

Cell Rep. 2015 Jan 20;10(3):307-316. doi: 10.1016/j.celrep.2014.12.035. Epub 2015 Jan 15. Erratum in: Cell Rep. 2015 Feb 10;10(5):840.

37.

ShcA regulates late stages of T cell development and peripheral CD4+ T cell numbers.

Buckley MW, Trampont PC, Arandjelovic S, Fond AM, Juncadella IJ, Ravichandran KS.

J Immunol. 2015 Feb 15;194(4):1665-76. doi: 10.4049/jimmunol.1401728. Epub 2015 Jan 16.

38.

Apoptosis and engulfment by bronchial epithelial cells. Implications for allergic airway inflammation.

Penberthy KK, Juncadella IJ, Ravichandran KS.

Ann Am Thorac Soc. 2014 Dec;11 Suppl 5:S259-62. doi: 10.1513/AnnalsATS.201405-200AW. Review.

39.

Essential versus accessory aspects of cell death: recommendations of the NCCD 2015.

Galluzzi L, Bravo-San Pedro JM, Vitale I, Aaronson SA, Abrams JM, Adam D, Alnemri ES, Altucci L, Andrews D, Annicchiarico-Petruzzelli M, Baehrecke EH, Bazan NG, Bertrand MJ, Bianchi K, Blagosklonny MV, Blomgren K, Borner C, Bredesen DE, Brenner C, Campanella M, Candi E, Cecconi F, Chan FK, Chandel NS, Cheng EH, Chipuk JE, Cidlowski JA, Ciechanover A, Dawson TM, Dawson VL, De Laurenzi V, De Maria R, Debatin KM, Di Daniele N, Dixit VM, Dynlacht BD, El-Deiry WS, Fimia GM, Flavell RA, Fulda S, Garrido C, Gougeon ML, Green DR, Gronemeyer H, Hajnoczky G, Hardwick JM, Hengartner MO, Ichijo H, Joseph B, Jost PJ, Kaufmann T, Kepp O, Klionsky DJ, Knight RA, Kumar S, Lemasters JJ, Levine B, Linkermann A, Lipton SA, Lockshin RA, López-Otín C, Lugli E, Madeo F, Malorni W, Marine JC, Martin SJ, Martinou JC, Medema JP, Meier P, Melino S, Mizushima N, Moll U, Muñoz-Pinedo C, Nuñez G, Oberst A, Panaretakis T, Penninger JM, Peter ME, Piacentini M, Pinton P, Prehn JH, Puthalakath H, Rabinovich GA, Ravichandran KS, Rizzuto R, Rodrigues CM, Rubinsztein DC, Rudel T, Shi Y, Simon HU, Stockwell BR, Szabadkai G, Tait SW, Tang HL, Tavernarakis N, Tsujimoto Y, Vanden Berghe T, Vandenabeele P, Villunger A, Wagner EF, Walczak H, White E, Wood WG, Yuan J, Zakeri Z, Zhivotovsky B, Melino G, Kroemer G.

Cell Death Differ. 2015 Jan;22(1):58-73. doi: 10.1038/cdd.2014.137. Epub 2014 Sep 19. Review.

40.

Metabolic vulnerabilities in endometrial cancer.

Byrne FL, Poon IK, Modesitt SC, Tomsig JL, Chow JD, Healy ME, Baker WD, Atkins KA, Lancaster JM, Marchion DC, Moley KH, Ravichandran KS, Slack-Davis JK, Hoehn KL.

Cancer Res. 2014 Oct 15;74(20):5832-45. doi: 10.1158/0008-5472.CAN-14-0254. Epub 2014 Sep 9.

41.

Unexpected phenotype of mice lacking Shcbp1, a protein induced during T cell proliferation.

Buckley MW, Arandjelovic S, Trampont PC, Kim TS, Braciale TJ, Ravichandran KS.

PLoS One. 2014 Aug 25;9(8):e105576. doi: 10.1371/journal.pone.0105576. eCollection 2014.

42.

The adaptor protein GULP promotes Jedi-1-mediated phagocytosis through a clathrin-dependent mechanism.

Sullivan CS, Scheib JL, Ma Z, Dang RP, Schafer JM, Hickman FE, Brodsky FM, Ravichandran KS, Carter BD.

Mol Biol Cell. 2014 Jun 15;25(12):1925-36. doi: 10.1091/mbc.E13-11-0658. Epub 2014 Apr 17.

43.

Unexpected link between an antibiotic, pannexin channels and apoptosis.

Poon IK, Chiu YH, Armstrong AJ, Kinchen JM, Juncadella IJ, Bayliss DA, Ravichandran KS.

Nature. 2014 Mar 20;507(7492):329-34. doi: 10.1038/nature13147. Epub 2014 Mar 12.

44.

Identification of a novel mitochondrial uncoupler that does not depolarize the plasma membrane.

Kenwood BM, Weaver JL, Bajwa A, Poon IK, Byrne FL, Murrow BA, Calderone JA, Huang L, Divakaruni AS, Tomsig JL, Okabe K, Lo RH, Cameron Coleman G, Columbus L, Yan Z, Saucerman JJ, Smith JS, Holmes JW, Lynch KR, Ravichandran KS, Uchiyama S, Santos WL, Rogers GW, Okusa MD, Bayliss DA, Hoehn KL.

Mol Metab. 2013 Nov 28;3(2):114-23. doi: 10.1016/j.molmet.2013.11.005. eCollection 2014 Apr.

45.

Brain angiogenesis inhibitor 1 is expressed by gastric phagocytes during infection with Helicobacter pylori and mediates the recognition and engulfment of human apoptotic gastric epithelial cells.

Das S, Sarkar A, Ryan KA, Fox S, Berger AH, Juncadella IJ, Bimczok D, Smythies LE, Harris PR, Ravichandran KS, Crowe SE, Smith PD, Ernst PB.

FASEB J. 2014 May;28(5):2214-24. doi: 10.1096/fj.13-243238. Epub 2014 Feb 7.

46.

Apoptotic cell clearance: basic biology and therapeutic potential.

Poon IK, Lucas CD, Rossi AG, Ravichandran KS.

Nat Rev Immunol. 2014 Mar;14(3):166-80. doi: 10.1038/nri3607. Epub 2014 Jan 31. Review.

47.

Intrinsic properties and regulation of Pannexin 1 channel.

Chiu YH, Ravichandran KS, Bayliss DA.

Channels (Austin). 2014;8(2):103-9. doi: 10.4161/chan.27545. Epub 2014 Jan 13. Review.

48.

A MERry response after myocardial infarction.

Arandjelovic S, Ravichandran KS.

Circ Res. 2013 Sep 27;113(8):949-51. doi: 10.1161/CIRCRESAHA.113.302155. No abstract available.

49.

Phosphatidylserine receptor BAI1 and apoptotic cells as new promoters of myoblast fusion.

Hochreiter-Hufford AE, Lee CS, Kinchen JM, Sokolowski JD, Arandjelovic S, Call JA, Klibanov AL, Yan Z, Mandell JW, Ravichandran KS.

Nature. 2013 May 9;497(7448):263-7. doi: 10.1038/nature12135. Epub 2013 Apr 24.

50.

Mathematical investigation of how oncogenic ras mutants promote ras signaling.

Stites EC, Ravichandran KS.

Methods Mol Biol. 2012;880:69-85. doi: 10.1007/978-1-61779-833-7_5. Review.

PMID:
23361982

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