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Items: 1 to 50 of 95


Epithelial-Mesenchymal Transition during Metastasis of HPV-Negative Pharyngeal Squamous Cell Carcinoma.

Ihler F, Gratz R, Wolff HA, Weiss BG, Bertlich M, Kitz J, Salinas G, Rave-Fränk M, Canis M.

Biomed Res Int. 2018 Mar 6;2018:7929104. doi: 10.1155/2018/7929104. eCollection 2018.


Cell-Free Plasma DNA for Disease Stratification and Prognosis in Head and Neck Cancer.

Schirmer MA, Beck J, Leu M, Oellerich M, Rave-Fränk M, Walson PD, Schütz E, Canis M.

Clin Chem. 2018 Jun;64(6):959-970. doi: 10.1373/clinchem.2017.285668. Epub 2018 Apr 16.


Prognostic impact of RITA expression in patients with anal squamous cell carcinoma treated with chemoradiotherapy.

Rödel F, Steinhäuser K, Kreis NN, Friemel A, Martin D, Wieland U, Rave-Fränk M, Balermpas P, Fokas E, Louwen F, Rödel C, Yuan J.

Radiother Oncol. 2018 Feb;126(2):214-221. doi: 10.1016/j.radonc.2017.10.028. Epub 2017 Nov 6.


Absence of DNA double-strand breaks in human peripheral blood mononuclear cells after 3 Tesla magnetic resonance imaging assessed by γH2AX flow cytometry.

Fasshauer M, Krüwel T, Zapf A, Stahnke VC, Rave-Fränk M, Staab W, Sohns JM, Steinmetz M, Unterberg-Buchwald C, Schuster A, Ritter C, Lotz J.

Eur Radiol. 2018 Mar;28(3):1149-1156. doi: 10.1007/s00330-017-5056-9. Epub 2017 Oct 6.


Tumour-derived plasma cell-free DNA in patients with head and neck cancer: A short review.

Rave-Fränk M.

Cancer Radiother. 2017 Oct;21(6-7):554-556. doi: 10.1016/j.canrad.2017.08.105. Epub 2017 Aug 25. Review.


Simultaneous inhibition of IGF1R and EGFR enhances the efficacy of standard treatment for colorectal cancer by the impairment of DNA repair and the induction of cell death.

Oberthür R, Seemann H, Gehrig J, Rave-Fränk M, Bremmer F, Halpape R, Conradi LC, Scharf JG, Burfeind P, Kaulfuß S.

Cancer Lett. 2017 Oct 28;407:93-105. doi: 10.1016/j.canlet.2017.08.009. Epub 2017 Aug 18.


Chemoradiotherapy Resistance in Colorectal Cancer Cells is Mediated by Wnt/β-catenin Signaling.

Emons G, Spitzner M, Reineke S, Möller J, Auslander N, Kramer F, Hu Y, Beissbarth T, Wolff HA, Rave-Fränk M, Heßmann E, Gaedcke J, Ghadimi BM, Johnsen SA, Ried T, Grade M.

Mol Cancer Res. 2017 Nov;15(11):1481-1490. doi: 10.1158/1541-7786.MCR-17-0205. Epub 2017 Aug 15.


Human papilloma virus load and PD-1/PD-L1, CD8+ and FOXP3 in anal cancer patients treated with chemoradiotherapy: Rationale for immunotherapy.

Balermpas P, Martin D, Wieland U, Rave-Fränk M, Strebhardt K, Rödel C, Fokas E, Rödel F.

Oncoimmunology. 2017 Feb 6;6(3):e1288331. doi: 10.1080/2162402X.2017.1288331. eCollection 2017.


T cell abundance in blood predicts acute organ toxicity in chemoradiotherapy for head and neck cancer.

Beschel LM, Leu M, Reichardt SD, Rave-Fränk M, Schirmer MA, Stadelmann C, Canis M, Wolff HA, Reichardt HM.

Oncotarget. 2016 Oct 4;7(40):65902-65915. doi: 10.18632/oncotarget.11677.


Polo-like kinase 3 and phosphoT273 caspase-8 are associated with improved local tumor control and survival in patients with anal carcinoma treated with concomitant chemoradiotherapy.

Rödel F, Martin D, Helmke C, Balermpas P, Fokas E, Wieland U, Rave-Fränk M, Kitz J, Matthess Y, Raab M, Strebhardt K, Rödel C.

Oncotarget. 2016 Aug 16;7(33):53339-53349. doi: 10.18632/oncotarget.10801.


Induction of Lipocalin2 in a Rat Model of Lung Irradiation.

Sultan S, Ahmad S, Rave-Fränk M, Malik IA, Hess CF, Christiansen H, Cameron S.

Int J Mol Sci. 2016 Apr 28;17(5). pii: E637. doi: 10.3390/ijms17050637.


Erratum to: DAPK plays an important role in panobinostat-induced autophagy and commits cells to apoptosis under autophagy deficient conditions.

Gandesiri M, Chakilam S, Ivanovska J, Benderska N, Ocker M, Di Fazio P, Feoktistova M, Gali-Muhtasib H, Rave-Fränk M, Prante O, Christiansen H, Leverkus M, Hartmann A, Schneider-Stock R.

Apoptosis. 2016 May;21(5):671-4. doi: 10.1007/s10495-016-1224-7. No abstract available.


Reduced toxicity in the treatment of locally advanced rectal cancer: a comparison of volumetric modulated arc therapy and 3D conformal radiotherapy.

Dröge LH, Weber HE, Guhlich M, Leu M, Conradi LC, Gaedcke J, Hennies S, Herrmann MK, Rave-Fränk M, Wolff HA.

BMC Cancer. 2015 Oct 20;15:750. doi: 10.1186/s12885-015-1812-x.


Prognostic value of CXCL12 and CXCR4 in inoperable head and neck squamous cell carcinoma.

Rave-Fränk M, Tehrany N, Kitz J, Leu M, Weber HE, Burfeind P, Schliephake H, Canis M, Beissbarth T, Reichardt HM, Wolff HA.

Strahlenther Onkol. 2016 Jan;192(1):47-54. doi: 10.1007/s00066-015-0892-5. Epub 2015 Sep 15.


Role of PECAM-1 in radiation-induced liver inflammation.

Malik IA, Stange I, Martius G, Cameron S, Rave-Fränk M, Hess CF, Ellenrieder V, Wolff HA.

J Cell Mol Med. 2015 Oct;19(10):2441-52. doi: 10.1111/jcmm.12630. Epub 2015 Jul 14.


The anti-TNF-α antibody infliximab inhibits the expression of fat-transporter-protein FAT/CD36 in a selective hepatic-radiation mouse model.

Martius G, Cameron S, Rave-Fränk M, Hess CF, Wolff HA, Malik IA.

Int J Mol Sci. 2015 Mar 2;16(3):4682-97. doi: 10.3390/ijms16034682.


High-grade acute organ toxicity and p16(INK4A) expression as positive prognostic factors in primary radio(chemo)therapy for patients with head and neck squamous cell carcinoma.

Tehrany N, Kitz J, Rave-Fränk M, Lorenzen S, Li L, Küffer S, Hess CF, Burfeind P, Reichardt HM, Canis M, Beissbarth T, Wolff HA.

Strahlenther Onkol. 2015 Jul;191(7):566-72. doi: 10.1007/s00066-014-0801-3. Epub 2015 Jan 10.


Hepatic fat accumulation and regulation of FAT/CD36: an effect of hepatic irradiation.

Martius G, Alwahsh SM, Rave-Fränk M, Hess CF, Christiansen H, Ramadori G, Malik IA.

Int J Clin Exp Pathol. 2014 Jul 15;7(8):5379-92. eCollection 2014.


Preconditioning of the liver for efficient repopulation by primary hepatocyte transplants.

Krause P, Rave-Frank M, Christiansen H, Koenig S.

Methods Mol Biol. 2014;1213:29-39. doi: 10.1007/978-1-4939-1453-1_3.


Human papillomavirus DNA load and p16INK4a expression predict for local control in patients with anal squamous cell carcinoma treated with chemoradiotherapy.

Rödel F, Wieland U, Fraunholz I, Kitz J, Rave-Fränk M, Wolff HA, Weiss C, Wirtz R, Balermpas P, Fokas E, Rödel C.

Int J Cancer. 2015 Jan 15;136(2):278-88. doi: 10.1002/ijc.28979. Epub 2014 May 27.


Hepatocyte senescence induced by radiation and partial hepatectomy in rat liver.

Serra MP, Marongiu F, Sini M, Marongiu M, Contini A, Wolff H, Rave-Frank M, Krause P, Laconi E, Koenig S.

Int J Radiat Biol. 2014 Oct;90(10):876-83. doi: 10.3109/09553002.2014.922714. Epub 2014 Jun 25.


Ionizing radiation regulates cardiac Ca handling via increased ROS and activated CaMKII.

Sag CM, Wolff HA, Neumann K, Opiela MK, Zhang J, Steuer F, Sowa T, Gupta S, Schirmer M, Hünlich M, Rave-Fränk M, Hess CF, Anderson ME, Shah AM, Christiansen H, Maier LS.

Basic Res Cardiol. 2013 Nov;108(6):385. doi: 10.1007/s00395-013-0385-6. Epub 2013 Sep 26.


STAT3 inhibition sensitizes colorectal cancer to chemoradiotherapy in vitro and in vivo.

Spitzner M, Roesler B, Bielfeld C, Emons G, Gaedcke J, Wolff HA, Rave-Fränk M, Kramer F, Beissbarth T, Kitz J, Wienands J, Ghadimi BM, Ebner R, Ried T, Grade M.

Int J Cancer. 2014 Feb 15;134(4):997-1007. doi: 10.1002/ijc.28429. Epub 2013 Sep 3.


Rat model of fractionated (2 Gy/day) 60 Gy irradiation of the liver: long-term effects.

Rave-Fränk M, Malik IA, Christiansen H, Naz N, Sultan S, Amanzada A, Blaschke M, Cameron S, Ahmad S, Hess CF, Ramadori G, Moriconi F.

Radiat Environ Biophys. 2013 Aug;52(3):321-38. doi: 10.1007/s00411-013-0468-7. Epub 2013 Apr 18.


Death-associated protein kinase controls STAT3 activity in intestinal epithelial cells.

Chakilam S, Gandesiri M, Rau TT, Agaimy A, Vijayalakshmi M, Ivanovska J, Wirtz RM, Schulze-Luehrmann J, Benderska N, Wittkopf N, Chellappan A, Ruemmele P, Vieth M, Rave-Fränk M, Christiansen H, Hartmann A, Neufert C, Atreya R, Becker C, Steinberg P, Schneider-Stock R.

Am J Pathol. 2013 Mar;182(3):1005-20. doi: 10.1016/j.ajpath.2012.11.026. Retraction in: Am J Pathol. 2017 Jan;187(1):225.


Serum Lipocalin2 is a potential biomarker of liver irradiation damage.

Sultan S, Cameron S, Ahmad S, Malik IA, Schultze FC, Hielscher R, Rave-Fränk M, Hess CF, Ramadori G, Christiansen H.

Liver Int. 2013 Mar;33(3):459-68. doi: 10.1111/liv.12073. Epub 2013 Jan 18.


Differential regulation of ferritin subunits and iron transport proteins: an effect of targeted hepatic X-irradiation.

Naz N, Ahmad S, Cameron S, Moriconi F, Rave-Fränk M, Christiansen H, Hess CF, Ramadori G, Malik IA.

Biomed Res Int. 2013;2013:353106. doi: 10.1155/2013/353106. Epub 2013 Dec 12.


DAPK plays an important role in panobinostat-induced autophagy and commits cells to apoptosis under autophagy deficient conditions.

Gandesiri M, Chakilam S, Ivanovska J, Benderska N, Ocker M, Di Fazio P, Feoktistova M, Gali-Muhtasib H, Rave-Fränk M, Prante O, Christiansen H, Leverkus M, Hartmann A, Schneider-Stock R.

Apoptosis. 2012 Dec;17(12):1300-15. doi: 10.1007/s10495-012-0757-7. Erratum in: Apoptosis. 2016 May;21(5):671-4.


Testicular radiation dose after multimodal curative therapy for locally advanced rectal cancer. Influence on hormone levels, quality of life, and sexual functioning.

Hennies S, Wolff HA, Jung K, Rave-Fränk M, Gaedcke J, Ghadimi M, Hess CF, Becker H, Hermann RM, Christiansen H.

Strahlenther Onkol. 2012 Oct;188(10):926-32. Epub 2012 Aug 11.


High survivin expression as a risk factor in patients with anal carcinoma treated with concurrent chemoradiotherapy.

Fraunholz I, Rödel C, Distel L, Rave-Fränk M, Kohler D, Falk S, Rödel F.

Radiat Oncol. 2012 Jun 14;7:88. doi: 10.1186/1748-717X-7-88.


Radiation-induced damage in different segments of the rat intestine after external beam irradiation of the liver.

Cameron S, Schwartz A, Sultan S, Schaefer IM, Hermann R, Rave-Fränk M, Hess CF, Christiansen H, Ramadori G.

Exp Mol Pathol. 2012 Apr;92(2):243-58. doi: 10.1016/j.yexmp.2011.11.007. Epub 2011 Dec 29.


Acute toxicity of radiochemotherapy in rectal cancer patients: a risk particularly for carriers of the TGFB1 Pro25 variant.

Schirmer MA, Mergler CP, Rave-Fränk M, Herrmann MK, Hennies S, Gaedcke J, Conradi LC, Jo P, Beissbarth T, Hess CF, Becker H, Ghadimi M, Brockmöller J, Christiansen H, Wolff HA.

Int J Radiat Oncol Biol Phys. 2012 May 1;83(1):149-57. doi: 10.1016/j.ijrobp.2011.05.063. Epub 2011 Oct 12.


Silencing of the Wnt transcription factor TCF4 sensitizes colorectal cancer cells to (chemo-) radiotherapy.

Kendziorra E, Ahlborn K, Spitzner M, Rave-Fränk M, Emons G, Gaedcke J, Kramer F, Wolff HA, Becker H, Beissbarth T, Ebner R, Ghadimi BM, Pukrop T, Ried T, Grade M.

Carcinogenesis. 2011 Dec;32(12):1824-31. doi: 10.1093/carcin/bgr222. Epub 2011 Oct 8.


In regard to "Radiation-induced liver fibrosis is mitigated by gene therapy inhibiting transforming growth factor-β signalling in the rat" by Shi-Suo Du et al. (Int J Radiat Oncol Biol Phys 2010;78:1513-1523).

Christiansen H, Moriconi F, Rave-Fränk M, Malik IA, Hess CF, Ramadori G.

Int J Radiat Oncol Biol Phys. 2011 Jul 1;80(3):960; author reply 960-1. doi: 10.1016/j.ijrobp.2011.01.072. No abstract available.


Gender-specific acute organ toxicity during intensified preoperative radiochemotherapy for rectal cancer.

Wolff HA, Conradi LC, Schirmer M, Beissbarth T, Sprenger T, Rave-Fränk M, Hennies S, Hess CF, Becker H, Christiansen H, Liersch T.

Oncologist. 2011;16(5):621-31. doi: 10.1634/theoncologist.2010-0414. Epub 2011 May 9.


Fractionated external beam radiotherapy as a suitable preparative regimen for hepatocyte transplantation after partial hepatectomy.

Krause P, Wolff HA, Rave-Frank M, Schmidberger H, Becker H, Hess CF, Christiansen H, Koenig S.

Int J Radiat Oncol Biol Phys. 2011 Jul 15;80(4):1214-9. doi: 10.1016/j.ijrobp.2011.02.035. Epub 2011 Apr 20.


Comparison of the micronucleus and chromosome aberration techniques for the documentation of cytogenetic damage in radiochemotherapy-treated patients with rectal cancer.

Wolff HA, Hennies S, Herrmann MK, Rave-Fränk M, Eickelmann D, Virsik P, Jung K, Schirmer M, Ghadimi M, Hess CF, Hermann RM, Christiansen H.

Strahlenther Onkol. 2011 Jan;187(1):52-8. doi: 10.1007/s00066-010-2163-9. Epub 2010 Dec 23.


A putatively functional haplotype in the gene encoding transforming growth factor beta-1 as a potential biomarker for radiosensitivity.

Schirmer MA, Brockmöller J, Rave-Fränk M, Virsik P, Wilken B, Kühnle E, Campean R, Hoffmann AO, Müller K, Goetze RG, Neumann M, Janke JH, Nasser F, Wolff HA, Ghadimi BM, Schmidberger H, Hess CF, Christiansen H, Hille A.

Int J Radiat Oncol Biol Phys. 2011 Mar 1;79(3):866-74. doi: 10.1016/j.ijrobp.2010.08.040. Epub 2010 Dec 22.


PALB2 mutations in German and Russian patients with bilateral breast cancer.

Bogdanova N, Sokolenko AP, Iyevleva AG, Abysheva SN, Blaut M, Bremer M, Christiansen H, Rave-Fränk M, Dörk T, Imyanitov EN.

Breast Cancer Res Treat. 2011 Apr;126(2):545-50. doi: 10.1007/s10549-010-1290-4. Epub 2010 Dec 17.


Analysis of chemokine and chemokine receptor expression in squamous cell carcinoma of the head and neck (SCCHN) cell lines.

Wolff HA, Rolke D, Rave-Fränk M, Schirmer M, Eicheler W, Doerfler A, Hille A, Hess CF, Matthias C, Rödel RM, Christiansen H.

Radiat Environ Biophys. 2011 Mar;50(1):145-54. doi: 10.1007/s00411-010-0341-x. Epub 2010 Nov 18.


A gene expression signature for chemoradiosensitivity of colorectal cancer cells.

Spitzner M, Emons G, Kramer F, Gaedcke J, Rave-Fränk M, Scharf JG, Burfeind P, Becker H, Beissbarth T, Ghadimi BM, Ried T, Grade M.

Int J Radiat Oncol Biol Phys. 2010 Nov 15;78(4):1184-92. doi: 10.1016/j.ijrobp.2010.06.023.


Liver sinusoidal endothelial and biliary cell repopulation following irradiation and partial hepatectomy.

Krause P, Rave-Fränk M, Wolff HA, Becker H, Christiansen H, Koenig S.

World J Gastroenterol. 2010 Aug 21;16(31):3928-35.


Effect of tumour-cell-derived or recombinant keratinocyte growth factor (KGF) on proliferation and radioresponse of human epithelial tumour cells (HNSCC) and normal keratinocytes in vitro.

Hille A, Grüger S, Christiansen H, Wolff HA, Volkmer B, Lehmann J, Dörr W, Rave-Fränk M.

Radiat Environ Biophys. 2010 May;49(2):261-70. doi: 10.1007/s00411-010-0271-7. Epub 2010 Mar 7.


Single-dose gamma-irradiation induces up-regulation of chemokine gene expression and recruitment of granulocytes into the portal area but not into other regions of rat hepatic tissue.

Malik IA, Moriconi F, Sheikh N, Naz N, Khan S, Dudas J, Mansuroglu T, Hess CF, Rave-Fränk M, Christiansen H, Ramadori G.

Am J Pathol. 2010 Apr;176(4):1801-15. doi: 10.2353/ajpath.2010.090505. Epub 2010 Feb 25.


High-grade acute organ toxicity during preoperative radiochemotherapy as positive predictor for complete histopathologic tumor regression in multimodal treatment of locally advanced rectal cancer.

Wolff HA, Gaedcke J, Jung K, Hermann RM, Rothe H, Schirmer M, Liersch T, Herrmann MKA, Hennies S, Rave-Fränk M, Hess CF, Christiansen H.

Strahlenther Onkol. 2010 Jan;186(1):30-35. doi: 10.1007/s00066-009-2037-1. Epub 2009 Dec 28.


Spontaneous and radiation-induced chromosomal instability and persistence of chromosome aberrations after radiotherapy in lymphocytes from prostate cancer patients.

Hille A, Hofman-Hüther H, Kühnle E, Wilken B, Rave-Fränk M, Schmidberger H, Virsik P.

Radiat Environ Biophys. 2010 Mar;49(1):27-37. doi: 10.1007/s00411-009-0244-x. Epub 2009 Sep 18.


Effect of irradiation on gene expression of rat liver adhesion molecules: in vivo and in vitro studies.

Moriconi F, Malik I, Ahmad G, Dudas J, Rave-Fränk M, Vorwerk H, Hille A, Hess CF, Ramadori G, Christiansen H.

Strahlenther Onkol. 2009 Jul;185(7):460-8. doi: 10.1007/s00066-009-1964-1. Epub 2009 Aug 28.


Faecal calprotectin and lactoferrin values during irradiation of prostate cancer correlate with chronic radiation proctitis: results of a prospective study.

Hille A, Rave-Fränk M, Christiansen H, Herrmann MK, Kertesz T, Hermann RM, Wolff HA, Schirmer M, Hess CF, Ramadori G.

Scand J Gastroenterol. 2009;44(8):939-46. doi: 10.1080/00365520903039952.


Effect of tumour necrosis factor-alpha and irradiation alone or in combination on the viability of hepatocellular and biliary adenocarcinoma cell lines in vitro.

Qesaraku B, Dudas J, Rave-Fränk M, Hess CF, Ramadori G, Saile B, Christiansen H.

Liver Int. 2009 Jul;29(6):910-21. doi: 10.1111/j.1478-3231.2009.01980.x. Epub 2009 Feb 16.


Bioinformatic and functional analysis of TGFBR1 polymorphisms.

Schirmer MA, Hoffmann AO, Campean R, Janke JH, Zidek LM, Hoffmann M, Kruse M, Sehrt D, Tzvetkov MV, Rave-Fränk M, Brockmöller J.

Pharmacogenet Genomics. 2009 Apr;19(4):249-59. doi: 10.1097/FPC.0b013e32831cb5a7.


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