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Items: 22


What do primary immunodeficiencies tell us about the essentiality/redundancy of immune responses?

Fischer A, Rausell A.

Semin Immunol. 2018 Apr;36:13-16. doi: 10.1016/j.smim.2017.12.001. Epub 2017 Dec 8. Review.


Generation of adult human T-cell progenitors for immunotherapeutic applications.

Simons L, Ma K, de Chappedelaine C, Moiranghtem RD, Elkaim E, Olivré J, Susini S, Appourchaux K, Reimann C, Sadek H, Pellé O, Cagnard N, Magrin E, Lagresle-Peyrou C, Taghon T, Rausell A, Cavazzana M, André-Schmutz I.

J Allergy Clin Immunol. 2018 Apr;141(4):1491-1494.e4. doi: 10.1016/j.jaci.2017.10.034. Epub 2017 Dec 5. No abstract available.


Single-cell analysis identifies cellular markers of the HIV permissive cell.

Rato S, Rausell A, Muñoz M, Telenti A, Ciuffi A.

PLoS Pathog. 2017 Oct 26;13(10):e1006678. doi: 10.1371/journal.ppat.1006678. eCollection 2017 Oct.


Primary immunodeficiencies suggest redundancy within the human immune system.

Fischer A, Rausell A.

Sci Immunol. 2016 Dec 23;1(6). pii: eaah5861. doi: 10.1126/sciimmunol.aah5861. Review.


Innate immune defects in HIV permissive cell lines.

Rausell A, Muñoz M, Martinez R, Roger T, Telenti A, Ciuffi A.

Retrovirology. 2016 Jun 27;13(1):43. doi: 10.1186/s12977-016-0275-8.


The Characteristics of Heterozygous Protein Truncating Variants in the Human Genome.

Bartha I, Rausell A, McLaren PJ, Mohammadi P, Tardaguila M, Chaturvedi N, Fellay J, Telenti A.

PLoS Comput Biol. 2015 Dec 7;11(12):e1004647. doi: 10.1371/journal.pcbi.1004647. eCollection 2015 Dec.


Sincell: an R/Bioconductor package for statistical assessment of cell-state hierarchies from single-cell RNA-seq.

Juliá M, Telenti A, Rausell A.

Bioinformatics. 2015 Oct 15;31(20):3380-2. doi: 10.1093/bioinformatics/btv368. Epub 2015 Jun 22.


Identification of potential HIV restriction factors by combining evolutionary genomic signatures with functional analyses.

McLaren PJ, Gawanbacht A, Pyndiah N, Krapp C, Hotter D, Kluge SF, Götz N, Heilmann J, Mack K, Sauter D, Thompson D, Perreaud J, Rausell A, Munoz M, Ciuffi A, Kirchhoff F, Telenti A.

Retrovirology. 2015 May 16;12:41. doi: 10.1186/s12977-015-0165-5.


HIV-1 immune activation induces Siglec-1 expression and enhances viral trans-infection in blood and tissue myeloid cells.

Pino M, Erkizia I, Benet S, Erikson E, Fernández-Figueras MT, Guerrero D, Dalmau J, Ouchi D, Rausell A, Ciuffi A, Keppler OT, Telenti A, Kräusslich HG, Martinez-Picado J, Izquierdo-Useros N.

Retrovirology. 2015 May 7;12:37. doi: 10.1186/s12977-015-0160-x.


Evolutionary genomics and HIV restriction factors.

Pyndiah N, Telenti A, Rausell A.

Curr Opin HIV AIDS. 2015 Mar;10(2):79-83. doi: 10.1097/COH.0000000000000138. Review.


Analysis of stop-gain and frameshift variants in human innate immunity genes.

Rausell A, Mohammadi P, McLaren PJ, Bartha I, Xenarios I, Fellay J, Telenti A.

PLoS Comput Biol. 2014 Jul 24;10(7):e1003757. doi: 10.1371/journal.pcbi.1003757. eCollection 2014 Jul.


Hippocampal extracellular matrix levels and stochasticity in synaptic protein expression increase with age and are associated with age-dependent cognitive decline.

Végh MJ, Rausell A, Loos M, Heldring CM, Jurkowski W, van Nierop P, Paliukhovich I, Li KW, del Sol A, Smit AB, Spijker S, van Kesteren RE.

Mol Cell Proteomics. 2014 Nov;13(11):2975-85. doi: 10.1074/mcp.M113.032086. Epub 2014 Jul 20.


Genomics of host-pathogen interactions.

Rausell A, Telenti A.

Curr Opin Immunol. 2014 Oct;30:32-8. doi: 10.1016/j.coi.2014.06.001. Epub 2014 Jun 24. Review.


Transcriptional dissection of pancreatic tumors engrafted in mice.

Martinez-Garcia R, Juan D, Rausell A, Muñoz M, Baños N, Menéndez C, Lopez-Casas PP, Rico D, Valencia A, Hidalgo M.

Genome Med. 2014 Apr 16;6(4):27. doi: 10.1186/gm544. eCollection 2014.


HIV and innate immunity - a genomics perspective.

Rausell A, McLaren PJ, Telenti A.

F1000Prime Rep. 2013 Aug 1;5:29. doi: 10.12703/P5-29. eCollection 2013.


Immune-responsive gene 1 protein links metabolism to immunity by catalyzing itaconic acid production.

Michelucci A, Cordes T, Ghelfi J, Pailot A, Reiling N, Goldmann O, Binz T, Wegner A, Tallam A, Rausell A, Buttini M, Linster CL, Medina E, Balling R, Hiller K.

Proc Natl Acad Sci U S A. 2013 May 7;110(19):7820-5. doi: 10.1073/pnas.1218599110. Epub 2013 Apr 22.


The Ras protein superfamily: evolutionary tree and role of conserved amino acids.

Rojas AM, Fuentes G, Rausell A, Valencia A.

J Cell Biol. 2012 Jan 23;196(2):189-201. doi: 10.1083/jcb.201103008. Review. Erratum in: J Cell Biol. 2012 Feb 20;196(4):545.


JDet: interactive calculation and visualization of function-related conservation patterns in multiple sequence alignments and structures.

Muth T, García-Martín JA, Rausell A, Juan D, Valencia A, Pazos F.

Bioinformatics. 2012 Feb 15;28(4):584-6. doi: 10.1093/bioinformatics/btr688. Epub 2011 Dec 9.


Protein interactions and ligand binding: from protein subfamilies to functional specificity.

Rausell A, Juan D, Pazos F, Valencia A.

Proc Natl Acad Sci U S A. 2010 Feb 2;107(5):1995-2000. doi: 10.1073/pnas.0908044107. Epub 2010 Jan 19.


Phylogeny-independent detection of functional residues.

Pazos F, Rausell A, Valencia A.

Bioinformatics. 2006 Jun 15;22(12):1440-8. Epub 2006 Mar 21.


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