Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 196


NK cells mediate clearance of CD8+ T cell-resistant tumors in response to STING agonists.

Nicolai CJ, Wolf N, Chang IC, Kirn G, Marcus A, Ndubaku CO, McWhirter SM, Raulet DH.

Sci Immunol. 2020 Mar 20;5(45). pii: eaaz2738. doi: 10.1126/sciimmunol.aaz2738.


Author Correction: SLC19A1 transports immunoreactive cyclic dinucleotides.

Luteijn RD, Zaver SA, Gowen BG, Wyman SK, Garelis NE, Onia L, McWhirter SM, Katibah GE, Corn JE, Woodward JJ, Raulet DH.

Nature. 2020 Mar;579(7800):E12. doi: 10.1038/s41586-020-2064-8.


SLC19A1 transports immunoreactive cyclic dinucleotides.

Luteijn RD, Zaver SA, Gowen BG, Wyman SK, Garelis NE, Onia L, McWhirter SM, Katibah GE, Corn JE, Woodward JJ, Raulet DH.

Nature. 2019 Sep;573(7774):434-438. doi: 10.1038/s41586-019-1553-0. Epub 2019 Sep 11. Erratum in: Nature. 2020 Mar;579(7800):E12.


Targetable mechanisms driving immunoevasion of persistent senescent cells link chemotherapy-resistant cancer to aging.

Muñoz DP, Yannone SM, Daemen A, Sun Y, Vakar-Lopez F, Kawahara M, Freund AM, Rodier F, Wu JD, Desprez PY, Raulet DH, Nelson PS, van 't Veer LJ, Campisi J, Coppé JP.

JCI Insight. 2019 Jun 11;5. pii: 124716. doi: 10.1172/jci.insight.124716.


Tumor-Derived cGAMP Triggers a STING-Mediated Interferon Response in Non-tumor Cells to Activate the NK Cell Response.

Marcus A, Mao AJ, Lensink-Vasan M, Wang L, Vance RE, Raulet DH.

Immunity. 2018 Oct 16;49(4):754-763.e4. doi: 10.1016/j.immuni.2018.09.016.


Contribution of NK cells to immunotherapy mediated by PD-1/PD-L1 blockade.

Hsu J, Hodgins JJ, Marathe M, Nicolai CJ, Bourgeois-Daigneault MC, Trevino TN, Azimi CS, Scheer AK, Randolph HE, Thompson TW, Zhang L, Iannello A, Mathur N, Jardine KE, Kirn GA, Bell JC, McBurney MW, Raulet DH, Ardolino M.

J Clin Invest. 2018 Oct 1;128(10):4654-4668. doi: 10.1172/JCI99317. Epub 2018 Sep 10.


Tumor-derived CSF-1 induces the NKG2D ligand RAE-1δ on tumor-infiltrating macrophages.

Thompson TW, Jackson BT, Li PJ, Wang J, Kim AB, Huang KTH, Zhang L, Raulet DH.

Elife. 2018 May 14;7. pii: e32919. doi: 10.7554/eLife.32919.


Endothelial cells express NKG2D ligands and desensitize antitumor NK responses.

Thompson TW, Kim AB, Li PJ, Wang J, Jackson BT, Huang KTH, Zhang L, Raulet DH.

Elife. 2017 Dec 12;6. pii: e30881. doi: 10.7554/eLife.30881.


Natural-Killer-like B Cells Display the Phenotypic and Functional Characteristics of Conventional B Cells.

Kerdiles YM, Almeida FF, Thompson T, Chopin M, Vienne M, Bruhns P, Huntington ND, Raulet DH, Nutt SL, Belz GT, Vivier E.

Immunity. 2017 Aug 15;47(2):199-200. doi: 10.1016/j.immuni.2017.07.026. No abstract available.


Listening to each other: Infectious disease and cancer immunology.

Vance RE, Eichberg MJ, Portnoy DA, Raulet DH.

Sci Immunol. 2017 Jan 13;2(7). pii: eaai9339. doi: 10.1126/sciimmunol.aai9339. Review.


An RNA-Based Fluorescent Biosensor for High-Throughput Analysis of the cGAS-cGAMP-STING Pathway.

Bose D, Su Y, Marcus A, Raulet DH, Hammond MC.

Cell Chem Biol. 2016 Dec 22;23(12):1539-1549. doi: 10.1016/j.chembiol.2016.10.014. Epub 2016 Nov 23.


A Herpesviral induction of RAE-1 NKG2D ligand expression occurs through release of HDAC mediated repression.

Greene TT, Tokuyama M, Knudsen GM, Kunz M, Lin J, Greninger AL, DeFilippis VR, DeRisi JL, Raulet DH, Coscoy L.

Elife. 2016 Nov 22;5. pii: e14749. doi: 10.7554/eLife.14749.


Differential Role of Hematopoietic and Nonhematopoietic Cell Types in the Regulation of NK Cell Tolerance and Responsiveness.

Shifrin NT, Kissiov DU, Ardolino M, Joncker NT, Raulet DH.

J Immunol. 2016 Nov 15;197(10):4127-4136. doi: 10.4049/jimmunol.1402447. Epub 2016 Oct 19.


Bacterial Manipulation of NK Cell Regulatory Activity Increases Susceptibility to Listeria monocytogenes Infection.

Clark SE, Filak HC, Guthrie BS, Schmidt RL, Jamieson A, Merkel P, Knight V, Cole CM, Raulet DH, Lenz LL.

PLoS Pathog. 2016 Jun 13;12(6):e1005708. doi: 10.1371/journal.ppat.1005708. eCollection 2016 Jun.


Neutrophils Suppress Intraluminal NK Cell-Mediated Tumor Cell Clearance and Enhance Extravasation of Disseminated Carcinoma Cells.

Spiegel A, Brooks MW, Houshyar S, Reinhardt F, Ardolino M, Fessler E, Chen MB, Krall JA, DeCock J, Zervantonakis IK, Iannello A, Iwamoto Y, Cortez-Retamozo V, Kamm RD, Pittet MJ, Raulet DH, Weinberg RA.

Cancer Discov. 2016 Jun;6(6):630-49. doi: 10.1158/2159-8290.CD-15-1157. Epub 2016 Apr 12.


Cytokine therapy restores antitumor responses of NK cells rendered anergic in MHC I-deficient tumors.

Ardolino M, Raulet DH.

Oncoimmunology. 2015 Jun 5;5(1):e1002725. eCollection 2016.


Immunosurveillance and immunotherapy of tumors by innate immune cells.

Iannello A, Thompson TW, Ardolino M, Marcus A, Raulet DH.

Curr Opin Immunol. 2016 Feb;38:52-8. doi: 10.1016/j.coi.2015.11.001. Epub 2015 Dec 11. Review.


A forward genetic screen reveals novel independent regulators of ULBP1, an activating ligand for natural killer cells.

Gowen BG, Chim B, Marceau CD, Greene TT, Burr P, Gonzalez JR, Hesser CR, Dietzen PA, Russell T, Iannello A, Coscoy L, Sentman CL, Carette JE, Muljo SA, Raulet DH.

Elife. 2015 Nov 13;4. pii: e08474. doi: 10.7554/eLife.08474.


Bone Marrow Cell Rejection, MHC, NK Cells, and Missing Self Recognition: Ain't That Peculiar (with Apologies to Marvin Gaye).

Raulet DH.

J Immunol. 2015 Oct 1;195(7):2923-5. doi: 10.4049/jimmunol.1501804. No abstract available.


Cytokine treatment in cancer immunotherapy.

Ardolino M, Hsu J, Raulet DH.

Oncotarget. 2015 Aug 14;6(23):19346-7. No abstract available.


NKG2D expression by CD8+ T cells contributes to GVHD and GVT effects in a murine model of allogeneic HSCT.

Karimi MA, Bryson JL, Richman LP, Fesnak AD, Leichner TM, Satake A, Vonderheide RH, Raulet DH, Reshef R, Kambayashi T.

Blood. 2015 Jun 4;125(23):3655-63. doi: 10.1182/blood-2015-02-629006. Epub 2015 Mar 18.


Antitumor immunity. A shed NKG2D ligand that promotes natural killer cell activation and tumor rejection.

Deng W, Gowen BG, Zhang L, Wang L, Lau S, Iannello A, Xu J, Rovis TL, Xiong N, Raulet DH.

Science. 2015 Apr 3;348(6230):136-9. doi: 10.1126/science.1258867. Epub 2015 Mar 5.


Cytokine therapy reverses NK cell anergy in MHC-deficient tumors.

Ardolino M, Azimi CS, Iannello A, Trevino TN, Horan L, Zhang L, Deng W, Ring AM, Fischer S, Garcia KC, Raulet DH.

J Clin Invest. 2014 Nov;124(11):4781-94. doi: 10.1172/JCI74337. Epub 2014 Oct 20.


Immunosurveillance of senescent cancer cells by natural killer cells.

Iannello A, Raulet DH.

Oncoimmunology. 2014 Jan 1;3(1):e27616. Epub 2014 Jan 6.


NK cell self tolerance, responsiveness and missing self recognition.

Shifrin N, Raulet DH, Ardolino M.

Semin Immunol. 2014 Apr;26(2):138-44. doi: 10.1016/j.smim.2014.02.007. Epub 2014 Mar 12. Review.


RAE1 ligands for the NKG2D receptor are regulated by STING-dependent DNA sensor pathways in lymphoma.

Lam AR, Bert NL, Ho SS, Shen YJ, Tang LF, Xiong GM, Croxford JL, Koo CX, Ishii KJ, Akira S, Raulet DH, Gasser S.

Cancer Res. 2014 Apr 15;74(8):2193-2203. doi: 10.1158/0008-5472.CAN-13-1703. Epub 2014 Mar 3.


Recognition of tumors by the innate immune system and natural killer cells.

Marcus A, Gowen BG, Thompson TW, Iannello A, Ardolino M, Deng W, Wang L, Shifrin N, Raulet DH.

Adv Immunol. 2014;122:91-128. doi: 10.1016/B978-0-12-800267-4.00003-1. Review.


A selective role of NKG2D in inflammatory and autoimmune diseases.

Guerra N, Pestal K, Juarez T, Beck J, Tkach K, Wang L, Raulet DH.

Clin Immunol. 2013 Dec;149(3):432-9. doi: 10.1016/j.clim.2013.09.003. Epub 2013 Sep 14.


Immune surveillance of unhealthy cells by natural killer cells.

Iannello A, Raulet DH.

Cold Spring Harb Symp Quant Biol. 2013;78:249-57. doi: 10.1101/sqb.2013.78.020255. Epub 2013 Oct 17. Review.


p53-dependent chemokine production by senescent tumor cells supports NKG2D-dependent tumor elimination by natural killer cells.

Iannello A, Thompson TW, Ardolino M, Lowe SW, Raulet DH.

J Exp Med. 2013 Sep 23;210(10):2057-69. doi: 10.1084/jem.20130783. Epub 2013 Sep 16.


Evidence for natural killer cell memory.

Marcus A, Raulet DH.

Curr Biol. 2013 Sep 9;23(17):R817-20. doi: 10.1016/j.cub.2013.07.015. Review.


A simple and effective method for differentiating GFP and YFP by flow cytometry using the violet laser.

Marcus A, Raulet DH.

Cytometry A. 2013 Nov;83(11):973-4. doi: 10.1002/cyto.a.22347. Epub 2013 Sep 10. No abstract available.


Characterization of a novel NKG2D and NKp46 double-mutant mouse reveals subtle variations in the NK cell repertoire.

Sheppard S, Triulzi C, Ardolino M, Serna D, Zhang L, Raulet DH, Guerra N.

Blood. 2013 Jun 20;121(25):5025-33. doi: 10.1182/blood-2012-12-471607. Epub 2013 May 6.


HLA reduces killer cell Ig-like receptor expression level and frequency in a humanized mouse model.

van Bergen J, Thompson A, van Pel M, Retière C, Salvatori D, Raulet DH, Trowsdale J, Koning F.

J Immunol. 2013 Mar 15;190(6):2880-5. doi: 10.4049/jimmunol.1200650. Epub 2013 Feb 6.


ATM-dependent spontaneous regression of early Eμ-myc-induced murine B-cell leukemia depends on natural killer and T cells.

Croxford JL, Tang ML, Pan MF, Huang CW, Kamran N, Phua CM, Chng WJ, Ng SB, Raulet DH, Gasser S.

Blood. 2013 Mar 28;121(13):2512-21. doi: 10.1182/blood-2012-08-449025. Epub 2013 Jan 24.


Regulation of ligands for the NKG2D activating receptor.

Raulet DH, Gasser S, Gowen BG, Deng W, Jung H.

Annu Rev Immunol. 2013;31:413-41. doi: 10.1146/annurev-immunol-032712-095951. Epub 2013 Jan 3. Review.


RAE-1 ligands for the NKG2D receptor are regulated by E2F transcription factors, which control cell cycle entry.

Jung H, Hsiung B, Pestal K, Procyk E, Raulet DH.

J Exp Med. 2012 Dec 17;209(13):2409-22. doi: 10.1084/jem.20120565. Epub 2012 Nov 19.


Infection-induced regulation of natural killer cells by macrophages and collagen at the lymph node subcapsular sinus.

Coombes JL, Han SJ, van Rooijen N, Raulet DH, Robey EA.

Cell Rep. 2012 Jul 26;2(1):124-35. doi: 10.1016/j.celrep.2012.06.001. Epub 2012 Jul 5.


Impaired natural killer cell self-education and "missing-self" responses in Ly49-deficient mice.

Bélanger S, Tu MM, Rahim MM, Mahmoud AB, Patel R, Tai LH, Troke AD, Wilhelm BT, Landry JR, Zhu Q, Tung KS, Raulet DH, Makrigiannis AP.

Blood. 2012 Jul 19;120(3):592-602. doi: 10.1182/blood-2012-02-408732. Epub 2012 Jun 1. Erratum in: Blood. 2013 Oct 3;122(14):2525.


NKG2D mediates NK cell hyperresponsiveness and influenza-induced pathologies in a mouse model of chronic obstructive pulmonary disease.

Wortham BW, Eppert BL, Motz GT, Flury JL, Orozco-Levi M, Hoebe K, Panos RJ, Maxfield M, Glasser SW, Senft AP, Raulet DH, Borchers MT.

J Immunol. 2012 May 1;188(9):4468-75. doi: 10.4049/jimmunol.1102643. Epub 2012 Mar 30.


Immune activation resulting from NKG2D/ligand interaction promotes atherosclerosis.

Xia M, Guerra N, Sukhova GK, Yang K, Miller CK, Shi GP, Raulet DH, Xiong N.

Circulation. 2011 Dec 20;124(25):2933-43. doi: 10.1161/CIRCULATIONAHA.111.034850. Epub 2011 Nov 21.


Expression of the RAE-1 family of stimulatory NK-cell ligands requires activation of the PI3K pathway during viral infection and transformation.

Tokuyama M, Lorin C, Delebecque F, Jung H, Raulet DH, Coscoy L.

PLoS Pathog. 2011 Sep;7(9):e1002265. doi: 10.1371/journal.ppat.1002265. Epub 2011 Sep 22.


Innate or adaptive immunity? The example of natural killer cells.

Vivier E, Raulet DH, Moretta A, Caligiuri MA, Zitvogel L, Lanier LL, Yokoyama WM, Ugolini S.

Science. 2011 Jan 7;331(6013):44-9. doi: 10.1126/science.1198687. Review.


Stress-regulated targeting of the NKG2D ligand Mult1 by a membrane-associated RING-CH family E3 ligase.

Nice TJ, Deng W, Coscoy L, Raulet DH.

J Immunol. 2010 Nov 1;185(9):5369-76. doi: 10.4049/jimmunol.1000247. Epub 2010 Sep 24.


Chemotherapy-induced genotoxic stress promotes sensitivity to natural killer cell cytotoxicity by enabling missing-self recognition.

Fine JH, Chen P, Mesci A, Allan DS, Gasser S, Raulet DH, Carlyle JR.

Cancer Res. 2010 Sep 15;70(18):7102-13. doi: 10.1158/0008-5472.CAN-10-1316. Epub 2010 Sep 7.


Mature natural killer cells reset their responsiveness when exposed to an altered MHC environment.

Joncker NT, Shifrin N, Delebecque F, Raulet DH.

J Exp Med. 2010 Sep 27;207(10):2065-72. doi: 10.1084/jem.20100570. Epub 2010 Sep 6.


Beta 2-microglobulin deficient mice lack CD4-8+ cytolytic T cells. 1990.

Zijlstra M, Bix M, Simister NE, Loring JM, Raulet DH, Jaenisch R.

J Immunol. 2010 May 1;184(9):4587-91. No abstract available.


Endoplasmic reticulum aminopeptidase associated with antigen processing defines the composition and structure of MHC class I peptide repertoire in normal and virus-infected cells.

Blanchard N, Kanaseki T, Escobar H, Delebecque F, Nagarajan NA, Reyes-Vargas E, Crockett DK, Raulet DH, Delgado JC, Shastri N.

J Immunol. 2010 Mar 15;184(6):3033-42. doi: 10.4049/jimmunol.0903712. Epub 2010 Feb 19.


Recombination signal sequence-associated restriction on TCRdelta gene rearrangement affects the development of tissue-specific gammadelta T cells.

Uche UN, Huber CR, Raulet DH, Xiong N.

J Immunol. 2009 Oct 15;183(8):4931-9. doi: 10.4049/jimmunol.0901859.

Supplemental Content

Loading ...
Support Center