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Items: 1 to 50 of 110

1.

LMW-PTP targeting potentiates the effects of drugs used in chronic lymphocytic leukemia therapy.

Capitani N, Lori G, Paoli P, Patrussi L, Troilo A, Baldari CT, Raugei G, D'Elios MM.

Cancer Cell Int. 2019 Mar 21;19:67. doi: 10.1186/s12935-019-0786-1. eCollection 2019.

2.

Morin-dependent inhibition of low molecular weight protein tyrosine phosphatase (LMW-PTP) restores sensitivity to apoptosis during colon carcinogenesis: Studies in vitro and in vivo, in an Apc-driven model of colon cancer.

Lori G, Paoli P, Femia AP, Pranzini E, Caselli A, Tortora K, Romagnoli A, Raugei G, Caderni G.

Mol Carcinog. 2019 May;58(5):686-698. doi: 10.1002/mc.22962. Epub 2019 Jan 16.

PMID:
30582224
3.

Stromal-induced downregulation of miR-1247 promotes prostate cancer malignancy.

Taddei ML, Cavallini L, Ramazzotti M, Comito G, Pietrovito L, Morandi A, Giannoni E, Raugei G, Chiarugi P.

J Cell Physiol. 2019 Jun;234(6):8274-8285. doi: 10.1002/jcp.27679. Epub 2018 Oct 30. Review.

PMID:
30378132
4.

LMW-PTP modulates glucose metabolism in cancer cells.

Lori G, Gamberi T, Paoli P, Caselli A, Pranzini E, Marzocchini R, Modesti A, Raugei G.

Biochim Biophys Acta Gen Subj. 2018 Dec;1862(12):2533-2544. doi: 10.1016/j.bbagen.2018.08.003. Epub 2018 Aug 4. Review.

PMID:
30251652
5.

Targeting LMW-PTP to sensitize melanoma cancer cells toward chemo- and radiotherapy.

Lori G, Paoli P, Caselli A, Cirri P, Marzocchini R, Mangoni M, Talamonti C, Livi L, Raugei G.

Cancer Med. 2018 May;7(5):1933-1943. doi: 10.1002/cam4.1435. Epub 2018 Mar 24.

6.

Targeting stromal-induced pyruvate kinase M2 nuclear translocation impairs oxphos and prostate cancer metastatic spread.

Giannoni E, Taddei ML, Morandi A, Comito G, Calvani M, Bianchini F, Richichi B, Raugei G, Wong N, Tang D, Chiarugi P.

Oncotarget. 2015 Sep 15;6(27):24061-74.

7.

Early effects of corneal collagen cross-linking by iontophoresis in ex vivo human corneas.

Mencucci R, Ambrosini S, Paladini I, Favuzza E, Boccalini C, Raugei G, Vannelli GB, Marini M.

Graefes Arch Clin Exp Ophthalmol. 2015 Feb;253(2):277-86. doi: 10.1007/s00417-014-2836-7. Epub 2014 Nov 4.

PMID:
25363654
8.

Calreticulin mutation-specific immunostaining in myeloproliferative neoplasms: pathogenetic insight and diagnostic value.

Vannucchi AM, Rotunno G, Bartalucci N, Raugei G, Carrai V, Balliu M, Mannarelli C, Pacilli A, Calabresi L, Fjerza R, Pieri L, Bosi A, Manfredini R, Guglielmelli P.

Leukemia. 2014 Sep;28(9):1811-8. doi: 10.1038/leu.2014.100. Epub 2014 Mar 12.

9.

Mitochondrial Oxidative Stress due to Complex I Dysfunction Promotes Fibroblast Activation and Melanoma Cell Invasiveness.

Taddei ML, Giannoni E, Raugei G, Scacco S, Sardanelli AM, Papa S, Chiarugi P.

J Signal Transduct. 2012;2012:684592. doi: 10.1155/2012/684592. Epub 2012 Jan 4.

10.

EphA2 induces metastatic growth regulating amoeboid motility and clonogenic potential in prostate carcinoma cells.

Taddei ML, Parri M, Angelucci A, Bianchini F, Marconi C, Giannoni E, Raugei G, Bologna M, Calorini L, Chiarugi P.

Mol Cancer Res. 2011 Feb;9(2):149-60. doi: 10.1158/1541-7786.MCR-10-0298. Epub 2011 Jan 4.

11.

Kinase-dependent and -independent roles of EphA2 in the regulation of prostate cancer invasion and metastasis.

Taddei ML, Parri M, Angelucci A, Onnis B, Bianchini F, Giannoni E, Raugei G, Calorini L, Rucci N, Teti A, Bologna M, Chiarugi P.

Am J Pathol. 2009 Apr;174(4):1492-503. doi: 10.2353/ajpath.2009.080473. Epub 2009 Mar 5.

12.

Redox regulation of anoikis: reactive oxygen species as essential mediators of cell survival.

Giannoni E, Buricchi F, Grimaldi G, Parri M, Cialdai F, Taddei ML, Raugei G, Ramponi G, Chiarugi P.

Cell Death Differ. 2008 May;15(5):867-78. doi: 10.1038/cdd.2008.3. Epub 2008 Feb 8.

13.

The expression of low molecular weight protein tyrosine phosphatase is up-regulated in 1,2-dimethylhydrazine-induced colon tumours in rats.

Marzocchini R, Malentacchi F, Biagini M, Cirelli D, Luceri C, Caderni G, Raugei G.

Int J Cancer. 2008 Apr 1;122(7):1675-8.

14.

Redox-dependent and ligand-independent trans-activation of insulin receptor by globular adiponectin.

Fiaschi T, Buricchi F, Cozzi G, Matthias S, Parri M, Raugei G, Ramponi G, Chiarugi P.

Hepatology. 2007 Jul;46(1):130-9.

PMID:
17526025
15.

EphrinA1 activates a Src/focal adhesion kinase-mediated motility response leading to rho-dependent actino/myosin contractility.

Parri M, Buricchi F, Giannoni E, Grimaldi G, Mello T, Raugei G, Ramponi G, Chiarugi P.

J Biol Chem. 2007 Jul 6;282(27):19619-28. Epub 2007 Apr 22.

16.

Site-directed mutagenesis of two aromatic residues lining the active site pocket of the yeast Ltp1.

Paoli P, Modesti A, Magherini F, Gamberi T, Caselli A, Manao G, Raugei G, Camici G, Ramponi G.

Biochim Biophys Acta. 2007 May;1770(5):753-62. Epub 2007 Jan 8.

PMID:
17296269
17.

Integrin-mediated cell adhesion and spreading engage different sources of reactive oxygen species.

Taddei ML, Parri M, Mello T, Catalano A, Levine AD, Raugei G, Ramponi G, Chiarugi P.

Antioxid Redox Signal. 2007 Apr;9(4):469-81.

PMID:
17280488
18.

Redox regulation of ephrin/integrin cross-talk.

Buricchi F, Giannoni E, Grimaldi G, Parri M, Raugei G, Ramponi G, Chiarugi P.

Cell Adh Migr. 2007 Jan-Mar;1(1):33-42. Epub 2007 Jan 29.

19.

A novel redox-based switch: LMW-PTP oxidation enhances Grb2 binding and leads to ERK activation.

Giannoni E, Raugei G, Chiarugi P, Ramponi G.

Biochem Biophys Res Commun. 2006 Sep 22;348(2):367-73. Epub 2006 Jul 28.

PMID:
16890200
20.

Redox regulation of beta-actin during integrin-mediated cell adhesion.

Fiaschi T, Cozzi G, Raugei G, Formigli L, Ramponi G, Chiarugi P.

J Biol Chem. 2006 Aug 11;281(32):22983-91. Epub 2006 Jun 5.

21.

During muscle ageing the activation of the mitogenic signalling is not sufficient to guarantee cellular duplication.

Buricchi F, Chiarugi P, Fiaschi T, Giannoni E, Magnelli L, Fanti E, Raugei G, Ramponi G.

Ital J Biochem. 2005 Sep-Dec;54(3-4):258-67.

PMID:
16688935
22.

In Saccharomyces cerevisiae an unbalanced level of tyrosine phosphorylation down-regulates the Ras/PKA pathway.

Magherini F, Busti S, Gamberi T, Sacco E, Raugei G, Manao G, Ramponi G, Modesti A, Vanoni M.

Int J Biochem Cell Biol. 2006 Mar;38(3):444-60. Epub 2005 Nov 2.

PMID:
16297653
23.

Oxidation and inactivation of low molecular weight protein tyrosine phosphatase by the anticancer drug Aplidin.

Taddei ML, Chiarugi P, Cuevas C, Ramponi G, Raugei G.

Int J Cancer. 2006 Apr 15;118(8):2082-8.

24.

EphrinA1 repulsive response is regulated by an EphA2 tyrosine phosphatase.

Parri M, Buricchi F, Taddei ML, Giannoni E, Raugei G, Ramponi G, Chiarugi P.

J Biol Chem. 2005 Oct 7;280(40):34008-18. Epub 2005 Jul 28.

25.

Up-regulated expression of low molecular weight protein tyrosine phosphatases in different human cancers.

Malentacchi F, Marzocchini R, Gelmini S, Orlando C, Serio M, Ramponi G, Raugei G.

Biochem Biophys Res Commun. 2005 Sep 2;334(3):875-83.

PMID:
16036221
26.

Intracellular reactive oxygen species activate Src tyrosine kinase during cell adhesion and anchorage-dependent cell growth.

Giannoni E, Buricchi F, Raugei G, Ramponi G, Chiarugi P.

Mol Cell Biol. 2005 Aug;25(15):6391-403.

27.

Insulin inhibits platelet-derived growth factor-induced cell proliferation.

Cirri P, Taddei ML, Chiarugi P, Buricchi F, Caselli A, Paoli P, Giannoni E, Camici G, Manao G, Raugei G, Ramponi G.

Mol Biol Cell. 2005 Jan;16(1):73-83. Epub 2004 Nov 3.

28.

The in vivo tyrosine phosphorylation level of yeast immunophilin Fpr3 is influenced by the LMW-PTP Ltp1.

Magherini F, Gamberi T, Paoli P, Marchetta M, Biagini M, Raugei G, Camici G, Ramponi G, Modesti A.

Biochem Biophys Res Commun. 2004 Aug 20;321(2):424-31.

PMID:
15358193
29.

Expression of the Stp1 LMW-PTP and inhibition of protein CK2 display a cooperative effect on immunophilin Fpr3 tyrosine phosphorylation and Saccharomyces cerevisiae growth.

Marchetta M, Gamberi T, Sarno S, Magherini F, Raugei G, Camici G, Pinna LA, Modesti A.

Cell Mol Life Sci. 2004 May;61(10):1176-84.

PMID:
15141303
30.

LMW-PTP is a positive regulator of tumor onset and growth.

Chiarugi P, Taddei ML, Schiavone N, Papucci L, Giannoni E, Fiaschi T, Capaccioli S, Raugei G, Ramponi G.

Oncogene. 2004 May 13;23(22):3905-14.

PMID:
15021900
31.

ACYP1 gene possesses two alternative splicing forms that induce apoptosis.

Degl'Innocenti D, Marzocchini R, Malentacchi F, Ramazzotti M, Raugei G, Ramponi G.

IUBMB Life. 2004 Jan;56(1):29-33.

32.

Down-regulation of platelet-derived growth factor receptor signaling during myogenesis.

Fiaschi T, Chiarugi P, Buricchi F, Giannoni E, Taddei ML, Magnelli L, Cozzi G, Raugei G, Ramponi G.

Cell Mol Life Sci. 2003 Dec;60(12):2721-35.

PMID:
14685695
33.

Lymphocyte function-associated antigen-1-mediated T cell adhesion is impaired by low molecular weight phosphotyrosine phosphatase-dependent inhibition of FAK activity.

Giannoni E, Chiarugi P, Cozzi G, Magnelli L, Taddei ML, Fiaschi T, Buricchi F, Raugei G, Ramponi G.

J Biol Chem. 2003 Sep 19;278(38):36763-76. Epub 2003 Jun 18.

34.

Reactive oxygen species as essential mediators of cell adhesion: the oxidative inhibition of a FAK tyrosine phosphatase is required for cell adhesion.

Chiarugi P, Pani G, Giannoni E, Taddei L, Colavitti R, Raugei G, Symons M, Borrello S, Galeotti T, Ramponi G.

J Cell Biol. 2003 Jun 9;161(5):933-44.

35.

Characterization of a novel Drosophila melanogaster acylphosphatase.

Degl'Innocenti D, Ramazzotti M, Marzocchini R, Chiti F, Raugei G, Ramponi G.

FEBS Lett. 2003 Jan 30;535(1-3):171-4.

36.

Beta-catenin interacts with low-molecular-weight protein tyrosine phosphatase leading to cadherin-mediated cell-cell adhesion increase.

Taddei ML, Chiarugi P, Cirri P, Buricchi F, Fiaschi T, Giannoni E, Talini D, Cozzi G, Formigli L, Raugei G, Ramponi G.

Cancer Res. 2002 Nov 15;62(22):6489-99.

37.

Low molecular weight protein tyrosine phosphatases: small, but smart.

Raugei G, Ramponi G, Chiarugi P.

Cell Mol Life Sci. 2002 Jun;59(6):941-9. Review.

PMID:
12169024
38.

Insight into the role of low molecular weight phosphotyrosine phosphatase (LMW-PTP) on platelet-derived growth factor receptor (PDGF-r) signaling. LMW-PTP controls PDGF-r kinase activity through TYR-857 dephosphorylation.

Chiarugi P, Cirri P, Taddei ML, Giannoni E, Fiaschi T, Buricchi F, Camici G, Raugei G, Ramponi G.

J Biol Chem. 2002 Oct 4;277(40):37331-8. Epub 2002 Jul 30.

39.

New perspectives in PDGF receptor downregulation: the main role of phosphotyrosine phosphatases.

Chiarugi P, Cirri P, Taddei ML, Talini D, Doria L, Fiaschi T, Buricchi F, Giannoni E, Camici G, Raugei G, Ramponi G.

J Cell Sci. 2002 May 15;115(Pt 10):2219-32.

40.

Low molecular weight protein-tyrosine phosphatase is involved in growth inhibition during cell differentiation.

Fiaschi T, Chiarugi P, Buricchi F, Giannoni E, Taddei ML, Talini D, Cozzi G, Zecchi-Orlandini S, Raugei G, Ramponi G.

J Biol Chem. 2001 Dec 28;276(52):49156-63. Epub 2001 Oct 10.

41.

Two vicinal cysteines confer a peculiar redox regulation to low molecular weight protein tyrosine phosphatase in response to platelet-derived growth factor receptor stimulation.

Chiarugi P, Fiaschi T, Taddei ML, Talini D, Giannoni E, Raugei G, Ramponi G.

J Biol Chem. 2001 Sep 7;276(36):33478-87. Epub 2001 Jun 27.

42.

Expression of the small tyrosine phosphatase (Stp1) in Saccharomyces cerevisiae: a study on protein tyrosine phosphorylation.

Modesti A, Bini L, Carraresi L, Magherini F, Liberatori S, Pallini V, Manao G, Pinna LA, Raugei G, Ramponi G.

Electrophoresis. 2001 Feb;22(3):576-85.

PMID:
11258771
43.

LMW-PTP exerts a differential regulation on PDGF- and insulin-mediated signaling.

Taddei ML, Chiarugi P, Cirri P, Talini D, Camici G, Manao G, Raugei G, Ramponi G.

Biochem Biophys Res Commun. 2000 Apr 13;270(2):564-9.

PMID:
10753664
44.

Low molecular weight protein-tyrosine phosphatase controls the rate and the strength of NIH-3T3 cells adhesion through its phosphorylation on tyrosine 131 or 132.

Chiarugi P, Taddei ML, Cirri P, Talini D, Buricchi F, Camici G, Manao G, Raugei G, Ramponi G.

J Biol Chem. 2000 Dec 1;275(48):37619-27.

45.

Acylphosphatase is a strong apoptosis inducer in HeLa cell line.

Giannoni E, Cirri P, Paoli P, Fiaschi T, Camici G, Manao G, Raugei G, Ramponi G.

Mol Cell Biol Res Commun. 2000 May;3(5):264-70.

PMID:
10964749
46.
47.

The low M(r) protein-tyrosine phosphatase is involved in Rho-mediated cytoskeleton rearrangement after integrin and platelet-derived growth factor stimulation.

Chiarugi P, Cirri P, Taddei L, Giannoni E, Camici G, Manao G, Raugei G, Ramponi G.

J Biol Chem. 2000 Feb 18;275(7):4640-6.

48.

Acylphosphatase expression during macrophage differentiation and activation of U-937 cell line.

Degl'Innocenti D, Marzocchini R, Rosati F, Cellini E, Raugei G, Ramponi G.

Biochimie. 1999 Nov;81(11):1031-5.

PMID:
10575358
49.

Inhibitory effect of full-length human endostatin on in vitro angiogenesis.

Taddei L, Chiarugi P, Brogelli L, Cirri P, Magnelli L, Raugei G, Ziche M, Granger HJ, Chiarugi V, Ramponi G.

Biochem Biophys Res Commun. 1999 Sep 24;263(2):340-5.

PMID:
10491294
50.

The low Mr phosphotyrosine protein phosphatase behaves differently when phosphorylated at Tyr131 or Tyr132 by Src kinase.

Bucciantini M, Chiarugi P, Cirri P, Taddei L, Stefani M, Raugei G, Nordlund P, Ramponi G.

FEBS Lett. 1999 Jul 30;456(1):73-8.

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