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Items: 18


Increased lymphocyte activation and atherosclerosis in CD47-deficient mice.

Engelbertsen D, Autio A, Verwilligen RAF, Depuydt MAC, Newton G, Rattik S, Levinsohn E, Saggu G, Jarolim P, Wang H, Velazquez F, Lichtman AH, Luscinskas FW.

Sci Rep. 2019 Jul 23;9(1):10608. doi: 10.1038/s41598-019-46942-x.


Lack of Ability to Present Antigens on Major Histocompatibility Complex Class II Molecules Aggravates Atherosclerosis in ApoE-/- Mice.

Wigren M, Rattik S, Yao Mattisson I, Tomas L, Grönberg C, Söderberg I, Alm R, Sundius L, Ljungcrantz I, Björkbacka H, Fredrikson GN, Nilsson J.

Circulation. 2019 May 28;139(22):2554-2566. doi: 10.1161/CIRCULATIONAHA.118.039288. Epub 2019 Apr 30.


Sleep modulates haematopoiesis and protects against atherosclerosis.

McAlpine CS, Kiss MG, Rattik S, He S, Vassalli A, Valet C, Anzai A, Chan CT, Mindur JE, Kahles F, Poller WC, Frodermann V, Fenn AM, Gregory AF, Halle L, Iwamoto Y, Hoyer FF, Binder CJ, Libby P, Tafti M, Scammell TE, Nahrendorf M, Swirski FK.

Nature. 2019 Feb;566(7744):383-387. doi: 10.1038/s41586-019-0948-2. Epub 2019 Feb 13.


Gut intraepithelial T cells calibrate metabolism and accelerate cardiovascular disease.

He S, Kahles F, Rattik S, Nairz M, McAlpine CS, Anzai A, Selgrade D, Fenn AM, Chan CT, Mindur JE, Valet C, Poller WC, Halle L, Rotllan N, Iwamoto Y, Wojtkiewicz GR, Weissleder R, Libby P, Fernández-Hernando C, Drucker DJ, Nahrendorf M, Swirski FK.

Nature. 2019 Feb;566(7742):115-119. doi: 10.1038/s41586-018-0849-9. Epub 2019 Jan 30.


Self-reactive CD4+ IL-3+ T cells amplify autoimmune inflammation in myocarditis by inciting monocyte chemotaxis.

Anzai A, Mindur JE, Halle L, Sano S, Choi JL, He S, McAlpine CS, Chan CT, Kahles F, Valet C, Fenn AM, Nairz M, Rattik S, Iwamoto Y, Fairweather D, Walsh K, Libby P, Nahrendorf M, Swirski FK.

J Exp Med. 2019 Feb 4;216(2):369-383. doi: 10.1084/jem.20180722. Epub 2019 Jan 22.


Atherosclerosis: cell biology and lipoproteins.

Engelbertsen D, Rattik S, Björkbacka H.

Curr Opin Lipidol. 2019 Feb;30(1):50-52. doi: 10.1097/MOL.0000000000000562. No abstract available.


Elevated circulating effector memory T cells but similar levels of regulatory T cells in patients with type 2 diabetes mellitus and cardiovascular disease.

Rattik S, Engelbertsen D, Wigren M, Ljungcrantz I, Östling G, Persson M, Nordin Fredrikson G, Bengtsson E, Nilsson J, Björkbacka H.

Diab Vasc Dis Res. 2019 May;16(3):270-280. doi: 10.1177/1479164118817942. Epub 2018 Dec 21.


B cells treated with CTB-p210 acquire a regulatory phenotype in vitro and reduce atherosclerosis in apolipoprotein E deficient mice.

Rattik S, Mantani PT, Yao Mattisson I, Ljungcrantz I, Sundius L, Björkbacka H, Terrinoni M, Lebens M, Holmgren J, Nilsson J, Wigren M, Nordin Fredrikson G.

Vascul Pharmacol. 2018 Dec;111:54-61. doi: 10.1016/j.vph.2018.09.002. Epub 2018 Sep 19.


IL-23R Deficiency Does Not Impact Atherosclerotic Plaque Development in Mice.

Engelbertsen D, Depuydt MAC, Verwilligen RAF, Rattik S, Levinsohn E, Edsfeldt A, Kuperwaser F, Jarolim P, Lichtman AH.

J Am Heart Assoc. 2018 Apr 4;7(8). pii: e008257. doi: 10.1161/JAHA.117.008257.


IL-1R and MyD88 signalling in CD4+ T cells promote Th17 immunity and atherosclerosis.

Engelbertsen D, Rattik S, Wigren M, Vallejo J, Marinkovic G, Schiopu A, Björkbacka H, Nilsson J, Bengtsson E.

Cardiovasc Res. 2018 Jan 1;114(1):180-187. doi: 10.1093/cvr/cvx196.


The infarcted myocardium solicits GM-CSF for the detrimental oversupply of inflammatory leukocytes.

Anzai A, Choi JL, He S, Fenn AM, Nairz M, Rattik S, McAlpine CS, Mindur JE, Chan CT, Iwamoto Y, Tricot B, Wojtkiewicz GR, Weissleder R, Libby P, Nahrendorf M, Stone JR, Becher B, Swirski FK.

J Exp Med. 2017 Nov 6;214(11):3293-3310. doi: 10.1084/jem.20170689. Epub 2017 Oct 4.


On-demand erythrocyte disposal and iron recycling requires transient macrophages in the liver.

Theurl I, Hilgendorf I, Nairz M, Tymoszuk P, Haschka D, Asshoff M, He S, Gerhardt LM, Holderried TA, Seifert M, Sopper S, Fenn AM, Anzai A, Rattik S, McAlpine C, Theurl M, Wieghofer P, Iwamoto Y, Weber GF, Harder NK, Chousterman BG, Arvedson TL, McKee M, Wang F, Lutz OM, Rezoagli E, Babitt JL, Berra L, Prinz M, Nahrendorf M, Weiss G, Weissleder R, Lin HY, Swirski FK.

Nat Med. 2016 Aug;22(8):945-51. doi: 10.1038/nm.4146. Epub 2016 Jul 18.


Treatment with a GnRH receptor agonist, but not the GnRH receptor antagonist degarelix, induces atherosclerotic plaque instability in ApoE(-/-) mice.

Knutsson A, Hsiung S, Celik S, Rattik S, Mattisson IY, Wigren M, Scher HI, Nilsson J, Hultgårdh-Nilsson A.

Sci Rep. 2016 May 18;6:26220. doi: 10.1038/srep26220.


Decreased levels of stem cell factor in subjects with incident coronary events.

Wigren M, Rattik S, Hultman K, Björkbacka H, Nordin-Fredrikson G, Bengtsson E, Hedblad B, Siegbahn A, Gonçalves I, Nilsson J.

J Intern Med. 2016 Feb;279(2):180-91. doi: 10.1111/joim.12443. Epub 2015 Oct 14.


IL-22 affects smooth muscle cell phenotype and plaque formation in apolipoprotein E knockout mice.

Rattik S, Hultman K, Rauch U, Söderberg I, Sundius L, Ljungcrantz I, Hultgårdh-Nilsson A, Wigren M, Björkbacka H, Fredrikson GN, Nilsson J.

Atherosclerosis. 2015 Oct;242(2):506-14. doi: 10.1016/j.atherosclerosis.2015.08.006. Epub 2015 Aug 11.


High plasma levels of heparin-binding epidermal growth factor are associated with a more stable plaque phenotype and reduced incidence of coronary events.

Rattik S, Wigren M, Björkbacka H, Fredrikson GN, Hedblad B, Siegbahn A, Bengtsson E, Schiopu A, Edsfeldt A, Dunér P, Grufman H, Gonçalves I, Nilsson J.

Arterioscler Thromb Vasc Biol. 2015 Jan;35(1):222-8. doi: 10.1161/ATVBAHA.114.304369. Epub 2014 Oct 30.


Induction of T helper 2 responses against human apolipoprotein B100 does not affect atherosclerosis in ApoE-/- mice.

Engelbertsen D, Rattik S, Knutsson A, Björkbacka H, Bengtsson E, Nilsson J.

Cardiovasc Res. 2014 Jul 15;103(2):304-12. doi: 10.1093/cvr/cvu131. Epub 2014 May 27.


Mobilization of regulatory T cells in response to carotid injury does not influence subsequent neointima formation.

Saxena A, Björkbacka H, Ström Å, Rattik S, Berg KE, Gomez MF, Fredrikson GN, Nilsson J, Hultgårdh-Nilsson A.

PLoS One. 2012;7(12):e51556. doi: 10.1371/journal.pone.0051556. Epub 2012 Dec 11.

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