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The epigenetic impacts of endocrine disruptors on female reproduction across generations†.

Rattan S, Flaws JA.

Biol Reprod. 2019 May 11. pii: ioz081. doi: 10.1093/biolre/ioz081. [Epub ahead of print]


Curcumin and hormesis with particular emphasis on neural cells.

Calabrese EJ, Dhawan G, Kapoor R, Mattson MP, Rattan SI.

Food Chem Toxicol. 2019 Jul;129:399-404. doi: 10.1016/j.fct.2019.04.053. Epub 2019 Apr 30. Review.


Periostin Reexpression in Heart Disease Contributes to Cardiac Interstitial Remodeling by Supporting the Cardiac Myofibroblast Phenotype.

Dixon IMC, Landry NM, Rattan SG.

Adv Exp Med Biol. 2019;1132:35-41. doi: 10.1007/978-981-13-6657-4_4.


Exposure to di-(2-ethylhexyl) phthalate transgenerationally alters anxiety-like behavior and amygdala gene expression in adult male and female mice.

Hatcher KM, Willing J, Chiang C, Rattan S, Flaws JA, Mahoney MM.

Physiol Behav. 2019 Aug 1;207:7-14. doi: 10.1016/j.physbeh.2019.04.018. Epub 2019 Apr 22.


Prenatal exposure to di-(2-ethylhexyl) phthalate and high-fat diet synergistically disrupts mouse fetal oogenesis and affects folliculogenesis†.

Mirihagalle S, You T, Suh L, Patel C, Gao L, Rattan S, Qiao H.

Biol Reprod. 2019 Jun 1;100(6):1561-1570. doi: 10.1093/biolre/ioz051.


Phytochemicals Rosmarinic Acid, Ampelopsin, and Amorfrutin-A Can Modulate Age-Related Phenotype of Serially Passaged Human Skin Fibroblasts in vitro.

Sodagam L, Lewinska A, Kwasniewicz E, Kokhanovska S, Wnuk M, Siems K, Rattan SIS.

Front Genet. 2019 Feb 21;10:81. doi: 10.3389/fgene.2019.00081. eCollection 2019.


NF-κB and GATA-Binding Factor 6 Repress Transcription of Caveolins in Bladder Smooth Muscle Hypertrophy.

Thangavel C, Gomes CM, Zderic SA, Javed E, Addya S, Singh J, Das S, Birbe R, Den RB, Rattan S, Deshpande DA, Penn RB, Chacko S, Boopathi E.

Am J Pathol. 2019 Apr;189(4):847-867. doi: 10.1016/j.ajpath.2018.12.013. Epub 2019 Jan 30.


Consensus on the Management of Posterior Urethral Valves from Antenatal Period to Puberty.

Sharma S, Joshi M, Gupta DK, Abraham M, Mathur P, Mahajan JK, Gangopadhyay AN, Rattan SK, Vora R, Prasad GR, Bhattacharya NC, Samuj R, Rao KLN, Basu AK.

J Indian Assoc Pediatr Surg. 2019 Jan-Mar;24(1):4-14. doi: 10.4103/jiaps.JIAPS_148_18. Review.


Biomechanical properties of female dolphin reproductive tissue.

Orbach DN, Rattan S, Hogan M, Crosby AJ, Brennan PLR.

Acta Biomater. 2019 Mar 1;86:117-124. doi: 10.1016/j.actbio.2019.01.012. Epub 2019 Jan 11.


Ski drives an acute increase in MMP-9 gene expression and release in primary cardiac myofibroblasts.

Landry N, Kavosh MS, Filomeno KL, Rattan SG, Czubryt MP, Dixon IMC.

Physiol Rep. 2018 Nov;6(22):e13897. doi: 10.14814/phy2.13897.


The Functional Role of Zinc Finger E Box-Binding Homeobox 2 (Zeb2) in Promoting Cardiac Fibroblast Activation.

Jahan F, Landry NM, Rattan SG, Dixon IMC, Wigle JT.

Int J Mol Sci. 2018 Oct 17;19(10). pii: E3207. doi: 10.3390/ijms19103207.


Continuous intracorneal ring implantation for treatment of myopic astigmatism.

Rattan SA.

Int Med Case Rep J. 2018 Sep 12;11:217-220. doi: 10.2147/IMCRJ.S173167. eCollection 2018.


Biogerontology: research status, challenges and opportunities.

Rattan SIS.

Acta Biomed. 2018 Jun 7;89(2):291-301. doi: 10.23750/abm.v89i2.7403.


Aging Health and R&D for Healthy Longevity Must Be Included into the WHO Work Program.

Stambler I, Jin K, Lederman S, Barzilai N, Olshansky SJ, Omokaro E, Barratt J, Anisimov VN, Rattan S, Yang S, Forster M, Byles J.

Aging Dis. 2018 Apr 1;9(2):331-333. doi: 10.14336/AD.2017.1120. eCollection 2018 Apr. No abstract available.


Micromechanical characterization of soft, biopolymeric hydrogels: stiffness, resilience, and failure.

Rattan S, Li L, Lau HK, Crosby AJ, Kiick KL.

Soft Matter. 2018 May 9;14(18):3478-3489. doi: 10.1039/c8sm00501j.


Acidosis potentiates endothelium-dependent vasorelaxation and gap junction communication in the superior mesenteric artery.

Mohanty I, Parija SC, Suklabaidya S, Rattan S.

Eur J Pharmacol. 2018 May 15;827:22-31. doi: 10.1016/j.ejphar.2018.03.004. Epub 2018 Mar 7.


Myocardin regulates mitochondrial calcium homeostasis and prevents permeability transition.

Mughal W, Martens M, Field J, Chapman D, Huang J, Rattan S, Hai Y, Cheung KG, Kereliuk S, West AR, Cole LK, Hatch GM, Diehl-Jones W, Keijzer R, Dolinsky VW, Dixon IM, Parmacek MS, Gordon JW.

Cell Death Differ. 2018 Nov;25(10):1732-1748. doi: 10.1038/s41418-018-0073-z. Epub 2018 Mar 6.


Di(2-Ethylhexyl) Phthalate Exposure During Prenatal Development Causes Adverse Transgenerational Effects on Female Fertility in Mice.

Rattan S, Brehm E, Gao L, Flaws JA.

Toxicol Sci. 2018 Jun 1;163(2):420-429. doi: 10.1093/toxsci/kfy042.


Prenatal Exposure to Di(2-Ethylhexyl) Phthalate Causes Long-Term Transgenerational Effects on Female Reproduction in Mice.

Brehm E, Rattan S, Gao L, Flaws JA.

Endocrinology. 2018 Feb 1;159(2):795-809. doi: 10.1210/en.2017-03004.


Prenatal exposure to di(2-ethylhexyl) phthalate disrupts ovarian function in a transgenerational manner in female mice.

Rattan S, Brehm E, Gao L, Niermann S, Flaws JA.

Biol Reprod. 2018 Jan 1;98(1):130-145. doi: 10.1093/biolre/iox154.


In vivo magnetofection: a novel approach for targeted topical delivery of nucleic acids for rectoanal motility disorders.

Singh J, Mohanty I, Rattan S.

Am J Physiol Gastrointest Liver Physiol. 2018 Jan 1;314(1):G109-G118. doi: 10.1152/ajpgi.00233.2017. Epub 2017 Oct 19.


A preliminary attempt to establish multiple stress response profiles of human skin fibroblasts exposed to mild or severe stress during ageing in vitro.

Rattan SIS, Demirovic D, Nizard C.

Mech Ageing Dev. 2018 Mar;170:92-97. doi: 10.1016/j.mad.2017.09.005. Epub 2017 Sep 22.


Chronic exposure to rapamycin and episodic serum starvation modulate ageing of human fibroblasts in vitro.

Sodagam L, Lewinska A, Wnuk M, Rattan SIS.

Biogerontology. 2017 Oct;18(5):841-854. doi: 10.1007/s10522-017-9730-8. Epub 2017 Sep 7.


The Future of Ageing: not more of the same.

Sikora E, Rattan SIS.

Biogerontology. 2017 Aug;18(4):429-432. doi: 10.1007/s10522-017-9720-x. Epub 2017 Jul 5. No abstract available.


Role of differentially expressed microRNA-139-5p in the regulation of phenotypic internal anal sphincter smooth muscle tone.

Singh J, Mohanty I, Addya S, Phillips B, Mee Yong H, An SS, Penn RB, Rattan S.

Sci Rep. 2017 May 3;7(1):1477. doi: 10.1038/s41598-017-01550-5.


Exposure to endocrine disruptors during adulthood: consequences for female fertility.

Rattan S, Zhou C, Chiang C, Mahalingam S, Brehm E, Flaws JA.

J Endocrinol. 2017 Jun;233(3):R109-R129. doi: 10.1530/JOE-17-0023. Epub 2017 Mar 29. Review.


Bisphenol A Exposure, Ovarian Follicle Numbers, and Female Sex Steroid Hormone Levels: Results From a CLARITY-BPA Study.

Patel S, Brehm E, Gao L, Rattan S, Ziv-Gal A, Flaws JA.

Endocrinology. 2017 Jun 1;158(6):1727-1738. doi: 10.1210/en.2016-1887.


Review article: pathogenesis and clinical manifestations of gastrointestinal involvement in systemic sclerosis.

Kumar S, Singh J, Rattan S, DiMarino AJ, Cohen S, Jimenez SA.

Aliment Pharmacol Ther. 2017 Apr;45(7):883-898. doi: 10.1111/apt.13963. Epub 2017 Feb 9. Review.


Prenatal Exposure to DEHP Induces Premature Reproductive Senescence in Male Mice.

Barakat R, Lin PP, Rattan S, Brehm E, Canisso IF, Abosalum ME, Flaws JA, Hess R, Ko C.

Toxicol Sci. 2017 Mar 1;156(1):96-108. doi: 10.1093/toxsci/kfw248.


Ca2+/calmodulin/MLCK pathway initiates, and RhoA/ROCK maintains, the internal anal sphincter smooth muscle tone.

Rattan S.

Am J Physiol Gastrointest Liver Physiol. 2017 Jan 1;312(1):G63-G66. doi: 10.1152/ajpgi.00370.2016. Epub 2016 Dec 8. No abstract available.


Inhibition of autophagy inhibits the conversion of cardiac fibroblasts to cardiac myofibroblasts.

Gupta SS, Zeglinski MR, Rattan SG, Landry NM, Ghavami S, Wigle JT, Klonisch T, Halayko AJ, Dixon IM.

Oncotarget. 2016 Nov 29;7(48):78516-78531. doi: 10.18632/oncotarget.12392.


Aging-associated changes in microRNA expression profile of internal anal sphincter smooth muscle: Role of microRNA-133a.

Singh J, Boopathi E, Addya S, Phillips B, Rigoutsos I, Penn RB, Rattan S.

Am J Physiol Gastrointest Liver Physiol. 2016 Nov 1;311(5):G964-G973. doi: 10.1152/ajpgi.00290.2016. Epub 2016 Sep 15.


Natural product inspired design and synthesis of β-carboline and γ-lactone based molecular hybrids.

Singh D, Devi N, Kumar V, Malakar CC, Mehra S, Rattan S, Rawal RK, Singh V.

Org Biomol Chem. 2016 Sep 14;14(34):8154-66. doi: 10.1039/c6ob01216g. Epub 2016 Aug 11.


Role of muscarinic-3 receptor antibody in systemic sclerosis: correlation with disease duration and effects of IVIG.

Kumar S, Singh J, Kedika R, Mendoza F, Jimenez SA, Blomain ES, DiMarino AJ, Cohen S, Rattan S.

Am J Physiol Gastrointest Liver Physiol. 2016 Jun 1;310(11):G1052-60. doi: 10.1152/ajpgi.00034.2016. Epub 2016 May 12.


Association between common variable immunodeficiency and collagenous infiltrative disorders of the gastrointestinal tract: A series of four patients.

Mandaliya R, Burkart AL, DiMarino AJ, Rattan S, Cohen S.

Indian J Gastroenterol. 2016 Mar;35(2):133-8. doi: 10.1007/s12664-016-0633-4. Epub 2016 Apr 7.


Ageing with elegans: a research proposal to map healthspan pathways.

Luyten W, Antal P, Braeckman BP, Bundy J, Cirulli F, Fang-Yen C, Fuellen G, Leroi A, Liu Q, Martorell P, Metspalu A, Perola M, Ristow M, Saul N, Schoofs L, Siems K, Temmerman L, Smets T, Wolk A, Rattan SI.

Biogerontology. 2016 Aug;17(4):771-82. doi: 10.1007/s10522-016-9644-x. Epub 2016 Apr 4.


Chronic expression of Ski induces apoptosis and represses autophagy in cardiac myofibroblasts.

Zeglinski MR, Davies JJ, Ghavami S, Rattan SG, Halayko AJ, Dixon IM.

Biochim Biophys Acta. 2016 Jun;1863(6 Pt A):1261-8. doi: 10.1016/j.bbamcr.2016.03.027. Epub 2016 Mar 31.


Role of microRNAs in gastrointestinal smooth muscle fibrosis and dysfunction: novel molecular perspectives on the pathophysiology and therapeutic targeting.

Krishna CV, Singh J, Thangavel C, Rattan S.

Am J Physiol Gastrointest Liver Physiol. 2016 Apr 1;310(7):G449-59. doi: 10.1152/ajpgi.00445.2015. Epub 2016 Jan 28. Review.


Low doses of nanodiamonds and silica nanoparticles have beneficial hormetic effects in normal human skin fibroblasts in culture.

Mytych J, Wnuk M, Rattan SI.

Chemosphere. 2016 Apr;148:307-15. doi: 10.1016/j.chemosphere.2016.01.045. Epub 2016 Jan 24.


Biology of ageing: principles, challenges and perspectives.

Rattan SI.

Rom J Morphol Embryol. 2015;56(4):1251-3. Review.


Smooth Muscle Stiffness Sensitivity is Driven by Soluble and Insoluble ECM Chemistry.

Herrick WG, Rattan S, Nguyen TV, Grunwald MS, Barney CW, Crosby AJ, Peyton SR.

Cell Mol Bioeng. 2015 Sep 1;8(3):333-348. Epub 2015 May 28.


Survey of anal sphincter dysfunction using anal manometry in patients with fecal incontinence: a possible guide to therapy.

Mandaliya R, DiMarino AJ, Moleski S, Rattan S, Cohen S.

Ann Gastroenterol. 2015 Oct-Dec;28(4):469-74.


Effect of edible coating on the aromatic attributes of roasted coffee beans.

Rattan S, Parande AK, Ramalakshmi K, Nagaraju VD.

J Food Sci Technol. 2015 Sep;52(9):5470-83. doi: 10.1007/s13197-014-1707-x. Epub 2015 Jan 14.


Facing challenges in an ageing world.

López-Lluch G, Rattan SI.

Biogerontology. 2015 Oct;16(5):567-8. doi: 10.1007/s10522-015-9597-5. Epub 2015 Aug 4. No abstract available.


Bimodal effect of oxidative stress in internal anal sphincter smooth muscle.

Singh J, Kumar S, Rattan S.

Am J Physiol Gastrointest Liver Physiol. 2015 Sep 1;309(5):G292-300. doi: 10.1152/ajpgi.00125.2015. Epub 2015 Jul 2.


Effects of Endocrine-Disrupting Chemicals on the Ovary.

Patel S, Zhou C, Rattan S, Flaws JA.

Biol Reprod. 2015 Jul;93(1):20. doi: 10.1095/biolreprod.115.130336. Epub 2015 Jun 10. Review.


Basal level of autophagy is increased in aging human skin fibroblasts in vitro, but not in old skin.

Demirovic D, Nizard C, Rattan SI.

PLoS One. 2015 May 7;10(5):e0126546. doi: 10.1371/journal.pone.0126546. eCollection 2015.


Standardization and quality control in quantifying non-enzymatic oxidative protein modifications in relation to ageing and disease: Why is it important and why is it hard?

Nedić O, Rogowska-Wrzesinska A, Rattan SIS.

Redox Biol. 2015 Aug;5:91-100. doi: 10.1016/j.redox.2015.04.001. Epub 2015 Apr 14. Review.

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