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Items: 1 to 50 of 263

1.

Segmentability Differences Between Child-Directed and Adult-Directed Speech: A Systematic Test With an Ecologically Valid Corpus.

Cristia A, Dupoux E, Ratner NB, Soderstrom M.

Open Mind (Camb). 2019 Feb 1;3:13-22. doi: 10.1162/opmi_a_00022.

2.

The evolution and multi-molecular properties of NF1 cutaneous neurofibromas originating from C-fiber sensory endings and terminal Schwann cells at normal sites of sensory terminations in the skin.

Rice FL, Houk G, Wymer JP, Gosline SJC, Guinney J, Wu J, Ratner N, Jankowski MP, La Rosa S, Dockum M, Storey JR, Carroll SL, Albrecht PJ, Riccardi VM.

PLoS One. 2019 May 20;14(5):e0216527. doi: 10.1371/journal.pone.0216527. eCollection 2019.

3.

Editor's Note: Genomic and Molecular Characterization of Malignant Peripheral Nerve Sheath Tumor Identifies the IGF1R Pathway as a Primary Target for Treatment.

Yang J, Ylipää A, Sun Y, Zheng H, Chen K, Nykter M, Trent J, Ratner N, Lev DC, Zhang W.

Clin Cancer Res. 2019 May 15;25(10):3195. doi: 10.1158/1078-0432.CCR-19-1144. No abstract available.

PMID:
31092619
4.

RUNX represses Pmp22 to drive neurofibromagenesis.

Hall A, Choi K, Liu W, Rose J, Zhao C, Yu Y, Na Y, Cai Y, Coover RA, Lin Y, Dombi E, Kim M, Levanon D, Groner Y, Boscolo E, Pan D, Liu PP, Lu QR, Ratner N, Huang G, Wu J.

Sci Adv. 2019 Apr 24;5(4):eaau8389. doi: 10.1126/sciadv.aau8389. eCollection 2019 Apr.

5.

Proximity biotinylation identifies a set of conformation-specific interactions between Merlin and cell junction proteins.

Hennigan RF, Fletcher JS, Guard S, Ratner N.

Sci Signal. 2019 Apr 23;12(578). pii: eaau8749. doi: 10.1126/scisignal.aau8749.

PMID:
31015291
6.

Targeted Inhibition of the Dual Specificity Phosphatases DUSP1 and DUSP6 Suppress MPNST Growth via JNK.

Ramkissoon A, Chaney KE, Milewski D, Williams KB, Williams RL, Choi K, Miller A, Kalin TV, Pressey JG, Szabo S, Azam M, Largaespada DA, Ratner N.

Clin Cancer Res. 2019 Apr 1. doi: 10.1158/1078-0432.CCR-18-3224. [Epub ahead of print]

PMID:
30936125
7.

First International Conference on RASopathies and Neurofibromatoses in Asia: Identification and advances of new therapeutics.

Rauen KA, Alsaegh A, Ben-Shachar S, Berman Y, Blakeley J, Cordeiro I, Elgersma Y, Evans DG, Fisher MJ, Frayling IM, George J, Huson SM, Kerr B, Khire U, Korf B, Legius E, Messiaen L, van Minkelen R, Nampoothiri S, Ngeow J, Parada LF, Phadke S, Pillai A, Plotkin SR, Puri R, Raji A, Ramesh V, Ratner N, Shankar SP, Sharda S, Tambe A, Vikkula M, Widemann BC, Wolkenstein P, Upadhyaya M.

Am J Med Genet A. 2019 Jun;179(6):1091-1097. doi: 10.1002/ajmg.a.61125. Epub 2019 Mar 25.

PMID:
30908877
8.

iGEAK: an interactive gene expression analysis kit for seamless workflow using the R/shiny platform.

Choi K, Ratner N.

BMC Genomics. 2019 Mar 6;20(1):177. doi: 10.1186/s12864-019-5548-x.

9.

Cxcr3-expressing leukocytes are necessary for neurofibroma formation in mice.

Fletcher JS, Wu J, Jessen WJ, Pundavela J, Miller JA, Dombi E, Kim MO, Rizvi TA, Chetal K, Salomonis N, Ratner N.

JCI Insight. 2019 Feb 7;4(3). pii: 98601. doi: 10.1172/jci.insight.98601. [Epub ahead of print]

10.

STAT3 inhibition reduces macrophage number and tumor growth in neurofibroma.

Fletcher JS, Springer MG, Choi K, Jousma E, Rizvi TA, Dombi E, Kim MO, Wu J, Ratner N.

Oncogene. 2019 Apr;38(15):2876-2884. doi: 10.1038/s41388-018-0600-x. Epub 2018 Dec 12.

11.

Tonic ATP-mediated growth suppression in peripheral nerve glia requires arrestin-PP2 and is evaded in NF1.

Coover RA, Healy TE, Guo L, Chaney KE, Hennigan RF, Thomson CS, Aschbacher-Smith LE, Jankowski MP, Ratner N.

Acta Neuropathol Commun. 2018 Nov 23;6(1):127. doi: 10.1186/s40478-018-0635-9.

12.

Malignant peripheral nerve sheath tumor: Transformation in a patient with neurofibromatosis type 2.

Agresta L, Salloum R, Hummel TR, Ratner N, Mangano FT, Fuller C, McMasters RL, Pater L, Jones BV, Szabo S, Pressey JG.

Pediatr Blood Cancer. 2019 Feb;66(2):e27520. doi: 10.1002/pbc.27520. Epub 2018 Nov 8.

PMID:
30408304
13.

Defective transcription elongation in a subset of cancers confers immunotherapy resistance.

Modur V, Singh N, Mohanty V, Chung E, Muhammad B, Choi K, Chen X, Chetal K, Ratner N, Salomonis N, Weirauch MT, Waltz S, Huang G, Privette-Vinnedge L, Park JS, Janssen EM, Komurov K.

Nat Commun. 2018 Oct 23;9(1):4410. doi: 10.1038/s41467-018-06810-0.

14.

Proceedings of the fifth international RASopathies symposium: When development and cancer intersect.

Rauen KA, Schoyer L, Schill L, Stronach B, Albeck J, Andresen BS, Cavé H, Ellis M, Fruchtman SM, Gelb BD, Gibson CC, Gripp K, Hefner E, Huang WYC, Itkin M, Kerr B, Linardic CM, McMahon M, Oberlander B, Perlstein E, Ratner N, Rogers L, Schenck A, Shankar S, Shvartsman S, Stevenson DA, Stites EC, Stork PJS, Sun C, Therrien M, Ullian EM, Widemann BC, Yeh E, Zampino G, Zenker M, Timmer W, McCormick F.

Am J Med Genet A. 2018 Dec;176(12):2924-2929. doi: 10.1002/ajmg.a.40632. Epub 2018 Oct 10.

PMID:
30302932
15.

Genetically engineered minipigs model the major clinical features of human neurofibromatosis type 1.

Isakson SH, Rizzardi AE, Coutts AW, Carlson DF, Kirstein MN, Fisher J, Vitte J, Williams KB, Pluhar GE, Dahiya S, Widemann BC, Dombi E, Rizvi T, Ratner N, Messiaen L, Stemmer-Rachamimov AO, Fahrenkrug SC, Gutmann DH, Giovannini M, Moertel CL, Largaespada DA, Watson AL.

Commun Biol. 2018 Oct 2;1:158. doi: 10.1038/s42003-018-0163-y. eCollection 2018.

16.

Author Correction: AMP kinase promotes glioblastoma bioenergetics and tumour growth.

Chhipa RR, Fan Q, Anderson J, Muraleedharan R, Huang Y, Ciraolo G, Chen X, Waclaw R, Chow LM, Khuchua Z, Kofron M, Weirauch MT, Kendler A, McPherson C, Ratner N, Nakano I, Dasgupta N, Komurov K, Dasgupta B.

Nat Cell Biol. 2018 Nov;20(11):1328. doi: 10.1038/s41556-018-0203-3.

PMID:
30190576
17.

Publisher Correction: AMP kinase promotes glioblastoma bioenergetics and tumour growth.

Chhipa RR, Fan Q, Anderson J, Muraleedharan R, Huang Y, Ciraolo G, Chen X, Waclaw R, Chow LM, Khuchua Z, Kofron M, Weirauch MT, Kendler A, McPherson C, Ratner N, Nakano I, Dasgupta N, Komurov K, Dasgupta B.

Nat Cell Biol. 2018 Oct;20(10):1228. doi: 10.1038/s41556-018-0185-1.

PMID:
30089841
18.

AMP kinase promotes glioblastoma bioenergetics and tumour growth.

Chhipa RR, Fan Q, Anderson J, Muraleedharan R, Huang Y, Ciraolo G, Chen X, Waclaw R, Chow LM, Khuchua Z, Kofron M, Weirauch MT, Kendler A, McPherson C, Ratner N, Nakano I, Dasgupta N, Komurov K, Dasgupta B.

Nat Cell Biol. 2018 Jul;20(7):823-835. doi: 10.1038/s41556-018-0126-z. Epub 2018 Jun 18. Erratum in: Nat Cell Biol. 2018 Aug 8;:. Nat Cell Biol. 2018 Nov;20(11):1328.

19.

Is Putting SUGAR (Sampling Utterances of Grammatical Analysis Revised) Into Language Sample Analysis a Good Thing? A Response to Pavelko and Owens (2017).

Guo LY, Eisenberg S, Ratner NB, MacWhinney B.

Lang Speech Hear Serv Sch. 2018 Jul 5;49(3):622-627. doi: 10.1044/2018_LSHSS-17-0084.

20.

2016 Children's Tumor Foundation conference on neurofibromatosis type 1, neurofibromatosis type 2, and schwannomatosis.

Fisher MJ, Belzberg AJ, de Blank P, De Raedt T, Elefteriou F, Ferner RE, Giovannini M, Harris GJ, Kalamarides M, Karajannis MA, Kim A, Lázaro C, Le LQ, Li W, Listernick R, Martin S, Morrison H, Pasmant E, Ratner N, Schorry E, Ullrich NJ, Viskochil D, Weiss B, Widemann BC, Zhu Y, Bakker A, Serra E.

Am J Med Genet A. 2018 May;176(5):1258-1269. doi: 10.1002/ajmg.a.38675.

21.

Exploiting mitochondrial and metabolic homeostasis as a vulnerability in NF1 deficient cells.

Allaway RJ, Wood MD, Downey SL, Bouley SJ, Traphagen NA, Wells JD, Batra J, Melancon SN, Ringelberg C, Seibel W, Ratner N, Sanchez Y.

Oncotarget. 2017 Jul 18;9(22):15860-15875. doi: 10.18632/oncotarget.19335. eCollection 2018 Mar 23.

22.

Programming of Schwann Cells by Lats1/2-TAZ/YAP Signaling Drives Malignant Peripheral Nerve Sheath Tumorigenesis.

Wu LMN, Deng Y, Wang J, Zhao C, Wang J, Rao R, Xu L, Zhou W, Choi K, Rizvi TA, Remke M, Rubin JB, Johnson RL, Carroll TJ, Stemmer-Rachamimov AO, Wu J, Zheng Y, Xin M, Ratner N, Lu QR.

Cancer Cell. 2018 Feb 12;33(2):292-308.e7. doi: 10.1016/j.ccell.2018.01.005.

23.

Patient-Centered Care, Diabetes Empowerment, and Type 2 Diabetes Medication Adherence Among American Indian Patients.

Ratner NL, Davis EB, Lhotka LL, Wille SM, Walls ML.

Clin Diabetes. 2017 Dec;35(5):281-285. doi: 10.2337/cd17-0008.

24.

Patient perspectives on loss of local obstetrical services in rural northern Minnesota.

Pearson J, Siebert K, Carlson S, Ratner N.

Birth. 2018 Sep;45(3):286-294. doi: 10.1111/birt.12325. Epub 2017 Dec 12.

PMID:
29230862
25.

Immune profiling of NF1-associated tumors reveals histologic subtype distinctions and heterogeneity: implications for immunotherapy.

Haworth KB, Arnold MA, Pierson CR, Choi K, Yeager ND, Ratner N, Roberts RD, Finlay JL, Cripe TP.

Oncotarget. 2017 May 30;8(47):82037-82048. doi: 10.18632/oncotarget.18301. eCollection 2017 Oct 10.

26.

Neurofibromatosis Type 1-Associated MPNST State of the Science: Outlining a Research Agenda for the Future.

Reilly KM, Kim A, Blakely J, Ferner RE, Gutmann DH, Legius E, Miettinen MM, Randall RL, Ratner N, Jumbé NL, Bakker A, Viskochil D, Widemann BC, Stewart DR.

J Natl Cancer Inst. 2017 Aug 1;109(8). doi: 10.1093/jnci/djx124. Review.

27.

A Collaborative Model for Accelerating the Discovery and Translation of Cancer Therapies.

Maertens O, McCurrach ME, Braun BS, De Raedt T, Epstein I, Huang TQ, Lauchle JO, Lee H, Wu J, Cripe TP, Clapp DW, Ratner N, Shannon K, Cichowski K.

Cancer Res. 2017 Nov 1;77(21):5706-5711. doi: 10.1158/0008-5472.CAN-17-1789. Epub 2017 Oct 9. Review.

28.

Oligodendrocyte RasG12V expressed in its endogenous locus disrupts myelin structure through increased MAPK, nitric oxide, and notch signaling.

Titus HE, López-Juárez A, Silbak SH, Rizvi TA, Bogard M, Ratner N.

Glia. 2017 Dec;65(12):1990-2002. doi: 10.1002/glia.23209. Epub 2017 Aug 30.

29.

Oligodendrocyte Nf1 Controls Aberrant Notch Activation and Regulates Myelin Structure and Behavior.

López-Juárez A, Titus HE, Silbak SH, Pressler JW, Rizvi TA, Bogard M, Bennett MR, Ciraolo G, Williams MT, Vorhees CV, Ratner N.

Cell Rep. 2017 Apr 18;19(3):545-557. doi: 10.1016/j.celrep.2017.03.073.

30.

An inflammatory gene signature distinguishes neurofibroma Schwann cells and macrophages from cells in the normal peripheral nervous system.

Choi K, Komurov K, Fletcher JS, Jousma E, Cancelas JA, Wu J, Ratner N.

Sci Rep. 2017 Mar 3;7:43315. doi: 10.1038/srep43315.

31.

Aurora A kinase inhibition enhances oncolytic herpes virotherapy through cytotoxic synergy and innate cellular immune modulation.

Currier MA, Sprague L, Rizvi TA, Nartker B, Chen CY, Wang PY, Hutzen BJ, Franczek MR, Patel AV, Chaney KE, Streby KA, Ecsedy JA, Conner J, Ratner N, Cripe TP.

Oncotarget. 2017 Mar 14;8(11):17412-17427. doi: 10.18632/oncotarget.14885.

32.

Activity of Selumetinib in Neurofibromatosis Type 1-Related Plexiform Neurofibromas.

Dombi E, Baldwin A, Marcus LJ, Fisher MJ, Weiss B, Kim A, Whitcomb P, Martin S, Aschbacher-Smith LE, Rizvi TA, Wu J, Ershler R, Wolters P, Therrien J, Glod J, Belasco JB, Schorry E, Brofferio A, Starosta AJ, Gillespie A, Doyle AL, Ratner N, Widemann BC.

N Engl J Med. 2016 Dec 29;375(26):2550-2560. doi: 10.1056/NEJMoa1605943.

33.

Infant-directed speech (IDS) vowel clarity and child language outcomes.

Hartman KM, Ratner NB, Newman RS.

J Child Lang. 2017 Sep;44(5):1140-1162. doi: 10.1017/S0305000916000520. Epub 2016 Dec 16.

PMID:
27978860
34.

Involvement of the Central Cognitive Mechanism in Word Production in Adults Who Stutter.

Tsai PT, Ratner NB.

J Speech Lang Hear Res. 2016 Dec 1;59(6):1269-1282. doi: 10.1044/2016_JSLHR-S-14-0224.

PMID:
27930777
35.

EGFR-Stat3 signalling in nerve glial cells modifies neurofibroma initiation.

Wu J, Liu W, Williams JP, Ratner N.

Oncogene. 2017 Mar 23;36(12):1669-1677. doi: 10.1038/onc.2016.386. Epub 2016 Oct 17.

36.

Forecasting the Future: Challenges and Opportunities in Developmental Communication Disorders.

Ratner NB.

Semin Speech Lang. 2016 Nov;37(4):229-230. Epub 2016 Oct 4. No abstract available.

PMID:
27701698
37.

HR23b expression is a potential predictive biomarker for HDAC inhibitor treatment in mesenchymal tumours and is associated with response to vorinostat.

Angelika Ihle M, Merkelbach-Bruse S, Hartmann W, Bauer S, Ratner N, Sonobe H, Nishio J, Larsson O, Åman P, Pedeutour F, Taguchi T, Wardelmann E, Buettner R, Schildhaus HU.

J Pathol Clin Res. 2016 Feb 5;2(2):59-71. doi: 10.1002/cjp2.35. eCollection 2016 Apr.

38.

CK2 blockade causes MPNST cell apoptosis and promotes degradation of β-catenin.

Kendall JJ, Chaney KE, Patel AV, Rizvi TA, Largaespada DA, Ratner N.

Oncotarget. 2016 Aug 16;7(33):53191-53203. doi: 10.18632/oncotarget.10668.

39.

An ShRNA Screen Identifies MEIS1 as a Driver of Malignant Peripheral Nerve Sheath Tumors.

Patel AV, Chaney KE, Choi K, Largaespada DA, Kumar AR, Ratner N.

EBioMedicine. 2016 Jul;9:110-119. doi: 10.1016/j.ebiom.2016.06.007. Epub 2016 Jun 4.

40.

An exploration of the role of executive functions in preschoolers' phonological development.

Torrington Eaton C, Ratner NB.

Clin Linguist Phon. 2016;30(9):679-95. doi: 10.1080/02699206.2016.1179344. Epub 2016 Jun 17.

PMID:
27315456
41.

Your Laptop to the Rescue: Using the Child Language Data Exchange System Archive and CLAN Utilities to Improve Child Language Sample Analysis.

Ratner NB, MacWhinney B.

Semin Speech Lang. 2016 May;37(2):74-84. doi: 10.1055/s-0036-1580742. Epub 2016 Apr 25. Review.

PMID:
27111268
42.

The "neuro" of neuroblastoma: Neuroblastoma as a neurodevelopmental disorder.

Ratner N, Brodeur GM, Dale RC, Schor NF.

Ann Neurol. 2016 Jul;80(1):13-23. doi: 10.1002/ana.24659. Epub 2016 Apr 30. Review.

43.

Insertional Mutagenesis Identifies a STAT3/Arid1b/β-catenin Pathway Driving Neurofibroma Initiation.

Wu J, Keng VW, Patmore DM, Kendall JJ, Patel AV, Jousma E, Jessen WJ, Choi K, Tschida BR, Silverstein KA, Fan D, Schwartz EB, Fuchs JR, Zou Y, Kim MO, Dombi E, Levy DE, Huang G, Cancelas JA, Stemmer-Rachamimov AO, Spinner RJ, Largaespada DA, Ratner N.

Cell Rep. 2016 Mar 1;14(8):1979-90. doi: 10.1016/j.celrep.2016.01.074. Epub 2016 Feb 18.

44.

Runx1: a new driver in neurofibromagenesis.

Wu J, Huang G, Ratner N.

Oncoscience. 2015 Nov 17;2(11):904-5. eCollection 2015. No abstract available.

45.

Placenta growth factor augments airway hyperresponsiveness via leukotrienes and IL-13.

Eiymo Mwa Mpollo MS, Brandt EB, Shanmukhappa SK, Arumugam PI, Tiwari S, Loberg A, Pillis D, Rizvi T, Lindsey M, Jonck B, Carmeliet P, Kalra VK, Le Cras TD, Ratner N, Wills-Karp M, Hershey GK, Malik P.

J Clin Invest. 2016 Feb;126(2):571-84. doi: 10.1172/JCI77250. Epub 2015 Dec 21.

46.

Correction to Electrochemical Detection of Low Concentrations of Mercury in Water Using Gold Nanoparticles.

Ratner N, Mandler D.

Anal Chem. 2015 Jul 21;87(14):7492. doi: 10.1021/acs.analchem.5b02313. Epub 2015 Jul 2. No abstract available.

PMID:
26133788
47.

Fatty acid synthase is a metabolic oncogene targetable in malignant peripheral nerve sheath tumors.

Patel AV, Johansson G, Colbert MC, Dasgupta B, Ratner N.

Neuro Oncol. 2015 Dec;17(12):1599-608. doi: 10.1093/neuonc/nov076. Epub 2015 Jun 26.

48.

Preclinical assessments of the MEK inhibitor PD-0325901 in a mouse model of Neurofibromatosis type 1.

Jousma E, Rizvi TA, Wu J, Janhofer D, Dombi E, Dunn RS, Kim MO, Masters AR, Jones DR, Cripe TP, Ratner N.

Pediatr Blood Cancer. 2015 Oct;62(10):1709-16. doi: 10.1002/pbc.25546. Epub 2015 Apr 22.

49.

Non-word repetition in 2-year-olds: Replication of an adapted paradigm and a useful methodological extension.

Torrington Eaton C, Newman RS, Ratner NB, Rowe ML.

Clin Linguist Phon. 2015 Jul;29(7):523-35. doi: 10.3109/02699206.2015.1029594. Epub 2015 Apr 20.

PMID:
25894670
50.

Electrochemical detection of low concentrations of mercury in water using gold nanoparticles.

Ratner N, Mandler D.

Anal Chem. 2015;87(10):5148-55. doi: 10.1021/ac504584f. Epub 2015 May 4. Erratum in: Anal Chem. 2015 Jul 21;87(14):7492.

PMID:
25892337

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