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Items: 1 to 50 of 64

1.

Src Family Kinases and p38 Mitogen-Activated Protein Kinases Regulate Pluripotent Cell Differentiation in Culture.

Tan BS, Kwek J, Wong CK, Saner NJ, Yap C, Felquer F, Morris MB, Gardner DK, Rathjen PD, Rathjen J.

PLoS One. 2016 Oct 10;11(10):e0163244. doi: 10.1371/journal.pone.0163244. eCollection 2016.

2.

Regulation of amino acid transporters in pluripotent cell populations in the embryo and in culture; novel roles for sodium-coupled neutral amino acid transporters.

Tan BSN, Rathjen PD, Harvey AJ, Gardner DK, Rathjen J.

Mech Dev. 2016 Aug;141:32-39. doi: 10.1016/j.mod.2016.06.003. Epub 2016 Jun 30.

3.

Endoderm complexity in the mouse gastrula is revealed through the expression of spink3.

Goh HN, Rathjen PD, Familari M, Rathjen J.

Biores Open Access. 2014 Jun 1;3(3):98-109. doi: 10.1089/biores.2014.0010.

4.

Regulation of pluripotent cell differentiation by a small molecule, staurosporine.

Hughes JN, Wong CK, Lau KX, Rathjen PD, Rathjen J.

Differentiation. 2014 Mar-Apr;87(3-4):101-10. doi: 10.1016/j.diff.2014.01.001. Epub 2014 Feb 28.

PMID:
24582574
5.

The formation of proximal and distal definitive endoderm populations in culture requires p38 MAPK activity.

Yap C, Goh HN, Familari M, Rathjen PD, Rathjen J.

J Cell Sci. 2014 May 15;127(Pt 10):2204-16. doi: 10.1242/jcs.134502. Epub 2014 Jan 30.

6.

Culture environment regulates amino acid turnover and glucose utilisation in human ES cells.

Rathjen J, Yeo C, Yap C, Tan BS, Rathjen PD, Gardner DK.

Reprod Fertil Dev. 2014 Jun;26(5):703-16. doi: 10.1071/RD12276.

PMID:
23759283
7.

A system to enrich for primitive streak-derivatives, definitive endoderm and mesoderm, from pluripotent cells in culture.

Vassilieva S, Goh HN, Lau KX, Hughes JN, Familari M, Rathjen PD, Rathjen J.

PLoS One. 2012;7(6):e38645. doi: 10.1371/journal.pone.0038645. Epub 2012 Jun 11.

8.

The amino acid transporter SNAT2 mediates L-proline-induced differentiation of ES cells.

Tan BS, Lonic A, Morris MB, Rathjen PD, Rathjen J.

Am J Physiol Cell Physiol. 2011 Jun;300(6):C1270-9. doi: 10.1152/ajpcell.00235.2010. Epub 2011 Feb 23.

9.

A requirement for FGF signalling in the formation of primitive streak-like intermediates from primitive ectoderm in culture.

Zheng Z, de Iongh RU, Rathjen PD, Rathjen J.

PLoS One. 2010 Sep 3;5(9):e12555. doi: 10.1371/journal.pone.0012555.

10.

Modulation of CP2 family transcriptional activity by CRTR-1 and sumoylation.

To S, Rodda SJ, Rathjen PD, Keough RA.

PLoS One. 2010 Jul 22;5(7):e11702. doi: 10.1371/journal.pone.0011702.

11.

Response to BMP4 signalling during ES cell differentiation defines intermediates of the ectoderm lineage.

Harvey NT, Hughes JN, Lonic A, Yap C, Long C, Rathjen PD, Rathjen J.

J Cell Sci. 2010 May 15;123(Pt 10):1796-804. doi: 10.1242/jcs.047530. Epub 2010 Apr 27.

12.

Embryonic stem cell-derived glial precursors as a vehicle for sulfamidase production in the MPS-IIIA mouse brain.

Robinson AJ, Zhao G, Rathjen J, Rathjen PD, Hutchinson RG, Eyre HJ, Hemsley KM, Hopwood JJ.

Cell Transplant. 2010;19(8):985-98. doi: 10.3727/096368910X498944. Epub 2010 Mar 26.

PMID:
20350350
13.

L-Proline induces differentiation of ES cells: a novel role for an amino acid in the regulation of pluripotent cells in culture.

Washington JM, Rathjen J, Felquer F, Lonic A, Bettess MD, Hamra N, Semendric L, Tan BS, Lake JA, Keough RA, Morris MB, Rathjen PD.

Am J Physiol Cell Physiol. 2010 May;298(5):C982-92. doi: 10.1152/ajpcell.00498.2009. Epub 2010 Feb 17.

14.

Genome-wide dynamics of replication timing revealed by in vitro models of mouse embryogenesis.

Hiratani I, Ryba T, Itoh M, Rathjen J, Kulik M, Papp B, Fussner E, Bazett-Jones DP, Plath K, Dalton S, Rathjen PD, Gilbert DM.

Genome Res. 2010 Feb;20(2):155-69. doi: 10.1101/gr.099796.109. Epub 2009 Dec 1.

15.

A novel role for gamma-secretase in the formation of primitive streak-like intermediates from ES cells in culture.

Hughes JN, Dodge N, Rathjen PD, Rathjen J.

Stem Cells. 2009 Dec;27(12):2941-51. doi: 10.1002/stem.218.

16.

Manipulation of cell:cell contacts and mesoderm suppressing activity direct lineage choice from pluripotent primitive ectoderm-like cells in culture.

Hughes JN, Washington JM, Zheng Z, Lau XK, Yap C, Rathjen PD, Rathjen J.

PLoS One. 2009;4(5):e5579. doi: 10.1371/journal.pone.0005579. Epub 2009 May 18.

17.

Understanding pluripotency--how embryonic stem cells keep their options open.

Johnson BV, Shindo N, Rathjen PD, Rathjen J, Keough RA.

Mol Hum Reprod. 2008 Sep;14(9):513-20. doi: 10.1093/molehr/gan048. Epub 2008 Aug 20. Review.

PMID:
18716052
18.

Transcriptional control of pluripotency: decisions in early development.

Johnson BV, Rathjen J, Rathjen PD.

Curr Opin Genet Dev. 2006 Oct;16(5):447-54. Epub 2006 Aug 17. Review.

PMID:
16919449
19.

A family of RS domain proteins with novel subcellular localization and trafficking.

Kavanagh SJ, Schulz TC, Davey P, Claudianos C, Russell C, Rathjen PD.

Nucleic Acids Res. 2005 Mar 1;33(4):1309-22. Print 2005.

20.

Differentiation of embryonic stem cells to a neural fate: a route to re-building the nervous system?

Lang KJ, Rathjen J, Vassilieva S, Rathjen PD.

J Neurosci Res. 2004 Apr 15;76(2):184-92. Review.

PMID:
15048916
21.
22.

Identification of a biological activity that supports maintenance and proliferation of pluripotent cells from the primitive ectoderm of the mouse.

Rathjen J, Washington JM, Bettess MD, Rathjen PD.

Biol Reprod. 2003 Dec;69(6):1863-71. Epub 2003 Aug 6.

PMID:
12904310
23.

Formation of neural precursor cell populations by differentiation of embryonic stem cells in vitro.

Rathjen J, Rathjen PD.

ScientificWorldJournal. 2002 Mar 12;2:690-700. Review.

24.

Embryonic stem cell differentiation and the analysis of mammalian development.

Rodda SJ, Kavanagh SJ, Rathjen J, Rathjen PD.

Int J Dev Biol. 2002;46(4):449-58. Review.

25.

Directed differentiation of pluripotent cells to neural lineages: homogeneous formation and differentiation of a neurectoderm population.

Rathjen J, Haines BP, Hudson KM, Nesci A, Dunn S, Rathjen PD.

Development. 2002 Jun;129(11):2649-61.

26.
27.

Lineage specific differentiation of pluripotent cells in vitro: a role for extraembryonic cell types.

Rathjen J, Dunn S, Bettess MD, Rathjen PD.

Reprod Fertil Dev. 2001;13(1):15-22.

PMID:
11545160
28.

Mouse ES cells: experimental exploitation of pluripotent differentiation potential.

Rathjen J, Rathjen PD.

Curr Opin Genet Dev. 2001 Oct;11(5):587-94. Review.

PMID:
11532403
29.

Histone variant H2A.Z is required for early mammalian development.

Faast R, Thonglairoam V, Schulz TC, Beall J, Wells JR, Taylor H, Matthaei K, Rathjen PD, Tremethick DJ, Lyons I.

Curr Biol. 2001 Aug 7;11(15):1183-7.

30.

Structure, sequence and function of a marsupial LIF gene: conservation of IL-6 family cytokines.

Cui S, Hope RM, Rathjen J, Voyle RB, Rathjen PD.

Cytogenet Cell Genet. 2001;92(3-4):271-8.

PMID:
11435700
31.

Interferon-inducible ES cell expression systems.

Whyatt LM, Rathjen PD.

Methods Mol Biol. 2001;158:301-18. Review. No abstract available.

PMID:
11236664
34.

Reversible programming of pluripotent cell differentiation.

Lake J, Rathjen J, Remiszewski J, Rathjen PD.

J Cell Sci. 2000 Feb;113 ( Pt 3):555-66.

35.

Developmental complexity of early mammalian pluripotent cell populations in vivo and in vitro.

Pelton TA, Bettess MD, Lake J, Rathjen J, Rathjen PD.

Reprod Fertil Dev. 1998;10(7-8):535-49. Review.

PMID:
10612459
36.
37.

Human germ cell tumor cell lines express novel leukemia inhibitory factor transcripts encoding differentially localized proteins.

Voyle RB, Haines BP, Pera MF, Forrest R, Rathjen PD.

Exp Cell Res. 1999 Jun 15;249(2):199-211.

PMID:
10366419
38.

Splice variants of the mouse Tec gene are differentially expressed in vivo.

Merkel AL, Atmosukarto II, Stevens K, Rathjen PD, Booker GW.

Cytogenet Cell Genet. 1999;84(1-2):132-9.

PMID:
10343129
39.
40.

Formation of a primitive ectoderm like cell population, EPL cells, from ES cells in response to biologically derived factors.

Rathjen J, Lake JA, Bettess MD, Washington JM, Chapman G, Rathjen PD.

J Cell Sci. 1999 Mar;112 ( Pt 5):601-12.

41.

Isolation and characterisation of a cDNA encoding a zona pellucida protein (ZPB) from the marsupial Trichosurus vulpecula (brushtail possum).

Haines BP, Rathjen PD, Hope RM, Whyatt LM, Holland MK, Breed WG.

Mol Reprod Dev. 1999 Feb;52(2):174-82.

PMID:
9890748
42.

Properties and uses of embryonic stem cells: prospects for application to human biology and gene therapy.

Rathjen PD, Lake J, Whyatt LM, Bettess MD, Rathjen J.

Reprod Fertil Dev. 1998;10(1):31-47. Review.

PMID:
9727591
43.

The mouse homeobox gene, Gbx2: genomic organization and expression in pluripotent cells in vitro and in vivo.

Chapman G, Remiszewski JL, Webb GC, Schulz TC, Bottema CD, Rathjen PD.

Genomics. 1997 Dec 1;46(2):223-33.

PMID:
9417909
45.

Trophic effects of myeloid leukaemia inhibitory factor (LIF) on mouse embryos.

Lavranos TC, Rathjen PD, Seamark RF.

J Reprod Fertil. 1995 Nov;105(2):331-8.

PMID:
8568779
46.

An unusual arrangement of 13 zinc fingers in the vertebrate gene Z13.

Schulz TC, Hopwood B, Rathjen PD, Wells JR.

Biochem J. 1995 Oct 1;311 ( Pt 1):219-24.

47.

Sequence and evolutionary conservation of the murine Gbx-2 homeobox gene.

Chapman G, Rathjen PD.

FEBS Lett. 1995 May 15;364(3):289-92.

48.

Sequence, genomic organization, and expression of the novel homeobox gene Hesx1.

Thomas PQ, Johnson BV, Rathjen J, Rathjen PD.

J Biol Chem. 1995 Feb 24;270(8):3869-75.

50.

Hesx1, a homeobox gene expressed by murine embryonic stem cells, maps to mouse chromosome 14, bands A3-B.

Webb GC, Thomas PQ, Ford JH, Rathjen PD.

Genomics. 1993 Nov;18(2):464-6. No abstract available.

PMID:
7904583

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