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Items: 16


Radiation drives the evolution of orthotopic xenografts initiated from glioblastoma stem-like cells.

McAbee JH, Rath BH, Valdez K, Young DL, Wu X, Shankavaram UT, Camphausen K, Tofilon PJ.

Cancer Res. 2019 Oct 15. pii: canres.2452.2019. doi: 10.1158/0008-5472.CAN-19-2452. [Epub ahead of print]


The XPO1 Inhibitor Selinexor Inhibits Translation and Enhances the Radiosensitivity of Glioblastoma Cells Grown In Vitro and In Vivo.

Wahba A, Rath BH, O'Neill JW, Camphausen K, Tofilon PJ.

Mol Cancer Ther. 2018 Aug;17(8):1717-1726. doi: 10.1158/1535-7163.MCT-17-1303. Epub 2018 Jun 4.


The DNA-PK Inhibitor VX-984 Enhances the Radiosensitivity of Glioblastoma Cells Grown In Vitro and as Orthotopic Xenografts.

Timme CR, Rath BH, O'Neill JW, Camphausen K, Tofilon PJ.

Mol Cancer Ther. 2018 Jun;17(6):1207-1216. doi: 10.1158/1535-7163.MCT-17-1267. Epub 2018 Mar 16.


Inhibition of the Histone H3K27 Demethylase UTX Enhances Tumor Cell Radiosensitivity.

Rath BH, Waung I, Camphausen K, Tofilon PJ.

Mol Cancer Ther. 2018 May;17(5):1070-1078. doi: 10.1158/1535-7163.MCT-17-1053. Epub 2018 Feb 26.


Exploiting Radiation-Induced Signaling to Increase the Susceptibility of Resistant Cancer Cells to Targeted Drugs: AKT and mTOR Inhibitors as an Example.

Eke I, Makinde AY, Aryankalayil MJ, Sandfort V, Palayoor ST, Rath BH, Liotta L, Pierobon M, Petricoin EF, Brown MF, Stommel JM, Ahmed MM, Coleman CN.

Mol Cancer Ther. 2018 Feb;17(2):355-367. doi: 10.1158/1535-7163.MCT-17-0262. Epub 2017 Aug 11.


Polysome Profiling Links Translational Control to the Radioresponse of Glioblastoma Stem-like Cells.

Wahba A, Rath BH, Bisht K, Camphausen K, Tofilon PJ.

Cancer Res. 2016 May 15;76(10):3078-87. doi: 10.1158/0008-5472.CAN-15-3050. Epub 2016 Mar 22.


Coculture with astrocytes reduces the radiosensitivity of glioblastoma stem-like cells and identifies additional targets for radiosensitization.

Rath BH, Wahba A, Camphausen K, Tofilon PJ.

Cancer Med. 2015 Nov;4(11):1705-16. doi: 10.1002/cam4.510. Epub 2015 Oct 30.


The mTORC1/mTORC2 inhibitor AZD2014 enhances the radiosensitivity of glioblastoma stem-like cells.

Kahn J, Hayman TJ, Jamal M, Rath BH, Kramp T, Camphausen K, Tofilon PJ.

Neuro Oncol. 2014 Jan;16(1):29-37. doi: 10.1093/neuonc/not139. Epub 2013 Dec 4.


The ATP-competitive mTOR inhibitor INK128 enhances in vitro and in vivo radiosensitivity of pancreatic carcinoma cells.

Hayman TJ, Wahba A, Rath BH, Bae H, Kramp T, Shankavaram UT, Camphausen K, Tofilon PJ.

Clin Cancer Res. 2014 Jan 1;20(1):110-9. doi: 10.1158/1078-0432.CCR-13-2136. Epub 2013 Nov 6.


Automated selection and harvesting of pluripotent stem cell colonies.

Haupt S, Grützner J, Thier MC, Kallweit T, Rath BH, Laufenberg I, Forgber M, Eberhardt J, Edenhofer F, Brüstle O.

Biotechnol Appl Biochem. 2012 Mar-Apr;59(2):77-87. doi: 10.1002/bab.1014.


Astrocytes enhance the invasion potential of glioblastoma stem-like cells.

Rath BH, Fair JM, Jamal M, Camphausen K, Tofilon PJ.

PLoS One. 2013;8(1):e54752. doi: 10.1371/journal.pone.0054752. Epub 2013 Jan 22.


The brain microenvironment preferentially enhances the radioresistance of CD133(+) glioblastoma stem-like cells.

Jamal M, Rath BH, Tsang PS, Camphausen K, Tofilon PJ.

Neoplasia. 2012 Feb;14(2):150-8.


Microenvironmental regulation of glioblastoma radioresponse.

Jamal M, Rath BH, Williams ES, Camphausen K, Tofilon PJ.

Clin Cancer Res. 2010 Dec 15;16(24):6049-59. doi: 10.1158/1078-0432.CCR-10-2435. Epub 2010 Oct 29. Erratum in: Clin Cancer Res. 2011 Apr 1;17(7):2068.


Residual tumor cells are unique cellular targets in glioblastoma.

Glas M, Rath BH, Simon M, Reinartz R, Schramme A, Trageser D, Eisenreich R, Leinhaas A, Keller M, Schildhaus HU, Garbe S, Steinfarz B, Pietsch T, Steindler DA, Schramm J, Herrlinger U, Brüstle O, Scheffler B.

Ann Neurol. 2010 Aug;68(2):264-9. doi: 10.1002/ana.22036.


Laser-assisted photoablation of human pluripotent stem cells from differentiating cultures.

Terstegge S, Winter F, Rath BH, Laufenberg I, Schwarz C, Leinhaas A, Levold F, Dolf A, Haupt S, Koch P, Endl E, Brüstle O.

Stem Cell Rev Rep. 2010 Jun;6(2):260-9. doi: 10.1007/s12015-010-9114-9.


Laser-assisted selection and passaging of human pluripotent stem cell colonies.

Terstegge S, Rath BH, Laufenberg I, Limbach N, Buchstaller A, Schütze K, Brüstle O.

J Biotechnol. 2009 Sep 10;143(3):224-30. doi: 10.1016/j.jbiotec.2009.07.002. Epub 2009 Jul 15.


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