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Items: 1 to 50 of 72

1.

Macrophage-derived netrin-1 promotes abdominal aortic aneurysm formation by activating MMP3 in vascular smooth muscle cells.

Hadi T, Boytard L, Silvestro M, Alebrahim D, Jacob S, Feinstein J, Barone K, Spiro W, Hutchison S, Simon R, Rateri D, Pinet F, Fenyo D, Adelman M, Moore KJ, Eltzschig HK, Daugherty A, Ramkhelawon B.

Nat Commun. 2018 Nov 27;9(1):5022. doi: 10.1038/s41467-018-07495-1.

2.

LRP1 (Low-Density Lipoprotein Receptor-Related Protein 1) Regulates Smooth Muscle Contractility by Modulating Ca2+ Signaling and Expression of Cytoskeleton-Related Proteins.

Au DT, Ying Z, Hernández-Ochoa EO, Fondrie WE, Hampton B, Migliorini M, Galisteo R, Schneider MF, Daugherty A, Rateri DL, Strickland DK, Muratoglu SC.

Arterioscler Thromb Vasc Biol. 2018 Nov;38(11):2651-2664. doi: 10.1161/ATVBAHA.118.311197.

PMID:
30354243
3.

Targeting hepatic heparin-binding EGF-like growth factor (HB-EGF) induces anti-hyperlipidemia leading to reduction of angiotensin II-induced aneurysm development.

Kim S, Yang L, Kim S, Lee RG, Graham MJ, Berliner JA, Lusis AJ, Cai L, Temel RE, Rateri DL, Lee S.

PLoS One. 2017 Aug 9;12(8):e0182566. doi: 10.1371/journal.pone.0182566. eCollection 2017.

4.

Smooth Muscle Cells Derived From Second Heart Field and Cardiac Neural Crest Reside in Spatially Distinct Domains in the Media of the Ascending Aorta-Brief Report.

Sawada H, Rateri DL, Moorleghen JJ, Majesky MW, Daugherty A.

Arterioscler Thromb Vasc Biol. 2017 Sep;37(9):1722-1726. doi: 10.1161/ATVBAHA.117.309599. Epub 2017 Jun 29.

5.

Relaxin and Matrix Metalloproteinase-9 in Angiotensin II-Induced Abdominal Aortic Aneurysms.

Howatt DA, Dajee M, Xie X, Moorleghen J, Rateri DL, Balakrishnan A, Da Cunha V, Johns DG, Gutstein DE, Daugherty A, Lu H.

Circ J. 2017 May 25;81(6):888-890. doi: 10.1253/circj.CJ-17-0229. Epub 2017 Apr 18.

6.

Transforming Growth Factor-β in Thoracic Aortic Aneurysms: Good, Bad, or Irrelevant?

Daugherty A, Chen Z, Sawada H, Rateri DL, Sheppard MB.

J Am Heart Assoc. 2017 Jan 24;6(1). pii: e005221. doi: 10.1161/JAHA.116.005221. No abstract available.

7.

miRs, miRs in the Wall, Who Is the Most Causative of Them All?

Sheppard M, Rateri DL, Daugherty A.

J Am Coll Cardiol. 2016 Jun 28;67(25):2978-80. doi: 10.1016/j.jacc.2015.12.078. No abstract available.

8.

TGF-β Neutralization Enhances AngII-Induced Aortic Rupture and Aneurysm in Both Thoracic and Abdominal Regions.

Chen X, Rateri DL, Howatt DA, Balakrishnan A, Moorleghen JJ, Cassis LA, Daugherty A.

PLoS One. 2016 Apr 22;11(4):e0153811. doi: 10.1371/journal.pone.0153811. eCollection 2016.

9.

Leukocyte Calpain Deficiency Reduces Angiotensin II-Induced Inflammation and Atherosclerosis But Not Abdominal Aortic Aneurysms in Mice.

Howatt DA, Balakrishnan A, Moorleghen JJ, Muniappan L, Rateri DL, Uchida HA, Takano J, Saido TC, Chishti AH, Baud L, Subramanian V.

Arterioscler Thromb Vasc Biol. 2016 May;36(5):835-45. doi: 10.1161/ATVBAHA.116.307285. Epub 2016 Mar 10.

10.

Subcutaneous Angiotensin II Infusion using Osmotic Pumps Induces Aortic Aneurysms in Mice.

Lu H, Howatt DA, Balakrishnan A, Moorleghen JJ, Rateri DL, Cassis LA, Daugherty A.

J Vis Exp. 2015 Sep 28;(103). doi: 10.3791/53191.

11.

Abdominal aortic aneurysm: novel mechanisms and therapies.

Davis FM, Rateri DL, Daugherty A.

Curr Opin Cardiol. 2015 Nov;30(6):566-73. doi: 10.1097/HCO.0000000000000216. Review.

12.

Fibroblast Angiotensin II Type 1a Receptors Contribute to Angiotensin II-Induced Medial Hyperplasia in the Ascending Aorta.

Poduri A, Rateri DL, Howatt DA, Balakrishnan A, Moorleghen JJ, Cassis LA, Daugherty A.

Arterioscler Thromb Vasc Biol. 2015 Sep;35(9):1995-2002. doi: 10.1161/ATVBAHA.115.305995. Epub 2015 Jul 9.

13.

Deficiency of Endogenous Acute-Phase Serum Amyloid A Protects apoE-/- Mice From Angiotensin II-Induced Abdominal Aortic Aneurysm Formation.

Webb NR, De Beer MC, Wroblewski JM, Ji A, Bailey W, Shridas P, Charnigo RJ, Noffsinger VP, Witta J, Howatt DA, Balakrishnan A, Rateri DL, Daugherty A, De Beer FC.

Arterioscler Thromb Vasc Biol. 2015 May;35(5):1156-65. doi: 10.1161/ATVBAHA.114.304776. Epub 2015 Mar 5.

14.

Smooth muscle cell deletion of low-density lipoprotein receptor-related protein 1 augments angiotensin II-induced superior mesenteric arterial and ascending aortic aneurysms.

Davis FM, Rateri DL, Balakrishnan A, Howatt DA, Strickland DK, Muratoglu SC, Haggerty CM, Fornwalt BK, Cassis LA, Daugherty A.

Arterioscler Thromb Vasc Biol. 2015 Jan;35(1):155-62. doi: 10.1161/ATVBAHA.114.304683. Epub 2014 Nov 13.

15.

Mechanisms of aortic aneurysm formation: translating preclinical studies into clinical therapies.

Davis FM, Rateri DL, Daugherty A.

Heart. 2014 Oct;100(19):1498-505. doi: 10.1136/heartjnl-2014-305648. Epub 2014 Jul 24. Review.

PMID:
25060754
16.

Angiotensin II induces region-specific medial disruption during evolution of ascending aortic aneurysms.

Rateri DL, Davis FM, Balakrishnan A, Howatt DA, Moorleghen JJ, O'Connor WN, Charnigo R, Cassis LA, Daugherty A.

Am J Pathol. 2014 Sep;184(9):2586-95. doi: 10.1016/j.ajpath.2014.05.014. Epub 2014 Jul 16.

17.

Aortic aneurysms in Loeys-Dietz syndrome - a tale of two pathways?

Davis F, Rateri DL, Daugherty A.

J Clin Invest. 2014 Jan;124(1):79-81. doi: 10.1172/JCI73906. Epub 2013 Dec 20.

18.

Deficiency of endogenous acute phase serum amyloid A does not affect atherosclerotic lesions in apolipoprotein E-deficient mice.

De Beer MC, Wroblewski JM, Noffsinger VP, Rateri DL, Howatt DA, Balakrishnan A, Ji A, Shridas P, Thompson JC, van der Westhuyzen DR, Tannock LR, Daugherty A, Webb NR, De Beer FC.

Arterioscler Thromb Vasc Biol. 2014 Feb;34(2):255-61. doi: 10.1161/ATVBAHA.113.302247. Epub 2013 Nov 21.

19.

Amlodipine reduces AngII-induced aortic aneurysms and atherosclerosis in hypercholesterolemic mice.

Chen X, Rateri DL, Howatt DA, Balakrishnan A, Moorleghen JJ, Morris AJ, Charnigo R, Cassis LA, Daugherty A.

PLoS One. 2013 Nov 14;8(11):e81743. doi: 10.1371/journal.pone.0081743. eCollection 2013.

20.

PD123319 augments angiotensin II-induced abdominal aortic aneurysms through an AT2 receptor-independent mechanism.

Daugherty A, Rateri DL, Howatt DA, Charnigo R, Cassis LA.

PLoS One. 2013 Apr 12;8(4):e61849. doi: 10.1371/journal.pone.0061849. Print 2013.

21.

Conundrum of angiotensin II and TGF-β interactions in aortic aneurysms.

Chen X, Lu H, Rateri DL, Cassis LA, Daugherty A.

Curr Opin Pharmacol. 2013 Apr;13(2):180-5. doi: 10.1016/j.coph.2013.01.002. Epub 2013 Mar 12. Review.

22.

Depletion of endothelial or smooth muscle cell-specific angiotensin II type 1a receptors does not influence aortic aneurysms or atherosclerosis in LDL receptor deficient mice.

Rateri DL, Moorleghen JJ, Knight V, Balakrishnan A, Howatt DA, Cassis LA, Daugherty A.

PLoS One. 2012;7(12):e51483. doi: 10.1371/journal.pone.0051483. Epub 2012 Dec 7.

23.

Adipocyte deficiency of angiotensinogen prevents obesity-induced hypertension in male mice.

Yiannikouris F, Gupte M, Putnam K, Thatcher S, Charnigo R, Rateri DL, Daugherty A, Cassis LA.

Hypertension. 2012 Dec;60(6):1524-30. doi: 10.1161/HYPERTENSIONAHA.112.192690. Epub 2012 Oct 29.

24.

Doxycycline does not influence established abdominal aortic aneurysms in angiotensin II-infused mice.

Xie X, Lu H, Moorleghen JJ, Howatt DA, Rateri DL, Cassis LA, Daugherty A.

PLoS One. 2012;7(9):e46411. doi: 10.1371/journal.pone.0046411. Epub 2012 Sep 27.

25.

Do vivarium conditions influence atherosclerotic lesion size?

Daugherty A, Rateri DL.

Arterioscler Thromb Vasc Biol. 2012 Oct;32(10):2339-40. doi: 10.1161/ATVBAHA.112.300117. No abstract available.

PMID:
22972938
26.

Citrullus lanatus 'sentinel' (watermelon) extract reduces atherosclerosis in LDL receptor-deficient mice.

Poduri A, Rateri DL, Saha SK, Saha S, Daugherty A.

J Nutr Biochem. 2013 May;24(5):882-6. doi: 10.1016/j.jnutbio.2012.05.011. Epub 2012 Aug 16.

27.

Novel mechanisms of abdominal aortic aneurysms.

Lu H, Rateri DL, Bruemmer D, Cassis LA, Daugherty A.

Curr Atheroscler Rep. 2012 Oct;14(5):402-12. doi: 10.1007/s11883-012-0271-y. Review.

28.

Involvement of the renin-angiotensin system in abdominal and thoracic aortic aneurysms.

Lu H, Rateri DL, Bruemmer D, Cassis LA, Daugherty A.

Clin Sci (Lond). 2012 Nov;123(9):531-43. doi: 10.1042/CS20120097. Review.

PMID:
22788237
29.

Transient exposure of neonatal female mice to testosterone abrogates the sexual dimorphism of abdominal aortic aneurysms.

Zhang X, Thatcher SE, Rateri DL, Bruemmer D, Charnigo R, Daugherty A, Cassis LA.

Circ Res. 2012 May 25;110(11):e73-85. doi: 10.1161/CIRCRESAHA.111.253880. Epub 2012 Apr 26.

30.

Protein kinase C-delta mediates adventitial cell migration through regulation of monocyte chemoattractant protein-1 expression in a rat angioplasty model.

Si Y, Ren J, Wang P, Rateri DL, Daugherty A, Shi XD, Kent KC, Liu B.

Arterioscler Thromb Vasc Biol. 2012 Apr;32(4):943-54. doi: 10.1161/ATVBAHA.111.244921. Epub 2012 Feb 9.

31.

Relevance of angiotensin II-induced aortic pathologies in mice to human aortic aneurysms.

Bruemmer D, Daugherty A, Lu H, Rateri DL.

Ann N Y Acad Sci. 2011 Dec;1245:7-10. doi: 10.1111/j.1749-6632.2011.06332.x. Review.

PMID:
22211965
32.

Adipocyte-specific deficiency of angiotensinogen decreases plasma angiotensinogen concentration and systolic blood pressure in mice.

Yiannikouris F, Karounos M, Charnigo R, English VL, Rateri DL, Daugherty A, Cassis LA.

Am J Physiol Regul Integr Comp Physiol. 2012 Jan 15;302(2):R244-51. doi: 10.1152/ajpregu.00323.2011. Epub 2011 Nov 9.

33.

MyD88 deficiency attenuates angiotensin II-induced abdominal aortic aneurysm formation independent of signaling through Toll-like receptors 2 and 4.

Owens AP 3rd, Rateri DL, Howatt DA, Moore KJ, Tobias PS, Curtiss LK, Lu H, Cassis LA, Daugherty A.

Arterioscler Thromb Vasc Biol. 2011 Dec;31(12):2813-9. doi: 10.1161/ATVBAHA.111.238642. Epub 2011 Sep 29.

34.

Prolonged infusion of angiotensin II in apoE(-/-) mice promotes macrophage recruitment with continued expansion of abdominal aortic aneurysm.

Rateri DL, Howatt DA, Moorleghen JJ, Charnigo R, Cassis LA, Daugherty A.

Am J Pathol. 2011 Sep;179(3):1542-8. doi: 10.1016/j.ajpath.2011.05.049. Epub 2011 Jul 19.

35.

Membrane cholesterol modulates the fluid shear stress response of polymorphonuclear leukocytes via its effects on membrane fluidity.

Zhang X, Hurng J, Rateri DL, Daugherty A, Schmid-Schönbein GW, Shin HY.

Am J Physiol Cell Physiol. 2011 Aug;301(2):C451-60. doi: 10.1152/ajpcell.00458.2010. Epub 2011 Apr 27.

36.

Endothelial cell-specific deficiency of Ang II type 1a receptors attenuates Ang II-induced ascending aortic aneurysms in LDL receptor-/- mice.

Rateri DL, Moorleghen JJ, Balakrishnan A, Owens AP 3rd, Howatt DA, Subramanian V, Poduri A, Charnigo R, Cassis LA, Daugherty A.

Circ Res. 2011 Mar 4;108(5):574-81. doi: 10.1161/CIRCRESAHA.110.222844. Epub 2011 Jan 20.

37.

Impact of serum amyloid A on high density lipoprotein composition and levels.

de Beer MC, Webb NR, Wroblewski JM, Noffsinger VP, Rateri DL, Ji A, van der Westhuyzen DR, de Beer FC.

J Lipid Res. 2010 Nov;51(11):3117-25. doi: 10.1194/jlr.M005413. Epub 2010 Jul 27.

38.

Total lymphocyte deficiency attenuates AngII-induced atherosclerosis in males but not abdominal aortic aneurysms in apoE deficient mice.

Uchida HA, Kristo F, Rateri DL, Lu H, Charnigo R, Cassis LA, Daugherty A.

Atherosclerosis. 2010 Aug;211(2):399-403. doi: 10.1016/j.atherosclerosis.2010.02.034. Epub 2010 Mar 4.

39.

Angiotensin II infusion promotes ascending aortic aneurysms: attenuation by CCR2 deficiency in apoE-/- mice.

Daugherty A, Rateri DL, Charo IF, Owens AP, Howatt DA, Cassis LA.

Clin Sci (Lond). 2010 Mar 9;118(11):681-9. doi: 10.1042/CS20090372.

40.

S100A12 links to thoracic aortic aneurysms.

Daugherty A, Rateri DL, Lu H.

Circ Res. 2010 Jan 8;106(1):13-5. doi: 10.1161/CIRCRESAHA.109.210757. No abstract available.

41.

Augmentation of the renin-angiotensin system by hypercholesterolemia promotes vascular diseases.

Daugherty A, Lu H, Rateri DL, Cassis LA.

Future Lipidol. 2008 Dec;3(6):625-636.

42.

Modes of defining atherosclerosis in mouse models: relative merits and evolving standards.

Daugherty A, Lu H, Howatt DA, Rateri DL.

Methods Mol Biol. 2009;573:1-15. doi: 10.1007/978-1-60761-247-6_1. Review.

PMID:
19763919
43.

Measuring blood pressure in mice using volume pressure recording, a tail-cuff method.

Daugherty A, Rateri D, Hong L, Balakrishnan A.

J Vis Exp. 2009 May 15;(27). pii: 1291. doi: 10.3791/1291.

44.

Atherosclerosis: cell biology and lipoproteins.

Daugherty A, Lu H, Rateri DL.

Curr Opin Lipidol. 2009 Jun;20(3):260-1. doi: 10.1097/MOL.0b013e32832bbd40. No abstract available.

PMID:
19433924
45.

ANG II infusion promotes abdominal aortic aneurysms independent of increased blood pressure in hypercholesterolemic mice.

Cassis LA, Gupte M, Thayer S, Zhang X, Charnigo R, Howatt DA, Rateri DL, Daugherty A.

Am J Physiol Heart Circ Physiol. 2009 May;296(5):H1660-5. doi: 10.1152/ajpheart.00028.2009. Epub 2009 Feb 27.

46.

As macrophages indulge, atherosclerotic lesions bulge.

Daugherty A, Rateri DL, Lu H.

Circ Res. 2008 Jun 20;102(12):1445-7. doi: 10.1161/CIRCRESAHA.108.178947. No abstract available.

47.

The role of the renin-angiotensin system in aortic aneurysmal diseases.

Lu H, Rateri DL, Cassis LA, Daugherty A.

Curr Hypertens Rep. 2008 Apr;10(2):99-106. Review.

48.

Atherosclerosis: cell biology and lipoproteins.

Daugherty A, Rateri DL.

Curr Opin Lipidol. 2008 Jun;19(3):328-9. doi: 10.1097/MOL.0b013e3282feec55. No abstract available.

PMID:
18460928
49.

Immunostaining of mouse atherosclerotic lesions.

Lu H, Rateri DL, Daugherty A.

Methods Mol Med. 2007;139:77-94.

PMID:
18287665
50.

Renin inhibition reduces hypercholesterolemia-induced atherosclerosis in mice.

Lu H, Rateri DL, Feldman DL, Charnigo RJ Jr, Fukamizu A, Ishida J, Oesterling EG, Cassis LA, Daugherty A.

J Clin Invest. 2008 Mar;118(3):984-93. doi: 10.1172/JCI32970.

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