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Items: 8

1.

On the Mechanism of the Asymmetric Aldol Addition of Chiral N-Amino Cyclic Carbamate Hydrazones: Evidence of Non-Curtin-Hammett Behavior.

Uddin MN, Knight JD, Rastelli EJ, Soubra-Ghaoui C, Albright TA, Wu CH, Wu JI, Coltart DM.

Chemistry. 2019 Oct 25. doi: 10.1002/chem.201902388. [Epub ahead of print]

PMID:
31650641
2.

Next-Generation Cell-Active Inhibitors of the Undrugged Oncogenic PTP4A3 Phosphatase.

Lazo JS, Blanco IK, Tasker NR, Rastelli EJ, Burnett JC, Garrott SR, Hart DJ, McCloud RL, Hsu KL, Wipf P, Sharlow ER.

J Pharmacol Exp Ther. 2019 Dec;371(3):652-662. doi: 10.1124/jpet.119.262188. Epub 2019 Oct 10.

PMID:
31601683
3.

Tapping the therapeutic potential of protein tyrosine phosphatase 4A with small molecule inhibitors.

Tasker NR, Rastelli EJ, Burnett JC, Sharlow ER, Lazo JS, Wipf P.

Bioorg Med Chem Lett. 2019 Aug 15;29(16):2008-2015. doi: 10.1016/j.bmcl.2019.06.048. Epub 2019 Jun 27. Review.

PMID:
31307888
4.

The antimalarial drug mefloquine enhances TP53 premature termination codon readthrough by aminoglycoside G418.

Ferguson MW, Gerak CAN, Chow CCT, Rastelli EJ, Elmore KE, Stahl F, Hosseini-Farahabadi S, Baradaran-Heravi A, Coltart DM, Roberge M.

PLoS One. 2019 May 23;14(5):e0216423. doi: 10.1371/journal.pone.0216423. eCollection 2019.

5.

In-flow photooxygenation of aminothienopyridinones generates iminopyridinedione PTP4A3 phosphatase inhibitors.

Tasker NR, Rastelli EJ, Blanco IK, Burnett JC, Sharlow ER, Lazo JS, Wipf P.

Org Biomol Chem. 2019 Feb 27;17(9):2448-2466. doi: 10.1039/c9ob00025a.

PMID:
30746541
6.

Asymmetric Induction in Hydroacylation by Cooperative Iminium Ion-Transition-Metal Catalysis.

Rastelli EJ, Truong NT, Coltart DM.

Org Lett. 2016 Nov 4;18(21):5588-5591. Epub 2016 Oct 21.

PMID:
27767317
7.

Asymmetric Synthesis of (+)-anti- and (-)-syn-Mefloquine Hydrochloride.

Rastelli EJ, Coltart DM.

J Org Chem. 2016 Oct 21;81(20):9567-9575. Epub 2016 Oct 6.

PMID:
27657347
8.

A Concise and Highly Enantioselective Total Synthesis of (+)-anti- and (-)-syn-Mefloquine Hydrochloride: Definitive Absolute Stereochemical Assignment of the Mefloquines.

Rastelli EJ, Coltart DM.

Angew Chem Int Ed Engl. 2015 Nov 16;54(47):14070-4. doi: 10.1002/anie.201507304. Epub 2015 Sep 30.

PMID:
26422780

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