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Items: 12


CDK7 inhibition suppresses Castration-Resistant Prostate Cancer through MED1 inactivation.

Rasool RU, Natesan R, Deng Q, Aras S, Lal P, Sander Effron S, Mitchell-Velasquez E, Posimo JM, Carskadon S, Baca SC, Pomerantz MM, Siddiqui J, Schwartz LE, Lee DJ, Palanisamy N, Narla G, Den RB, Freedman ML, Brady DC, Asangani IA.

Cancer Discov. 2019 Aug 29. pii: CD-19-0189. doi: 10.1158/2159-8290.CD-19-0189. [Epub ahead of print]


Vimentin activation in early apoptotic cancer cells errands survival pathways during DNA damage inducer CPT treatment in colon carcinoma model.

Chakraborty S, Kumar A, Faheem MM, Katoch A, Kumar A, Jamwal VL, Nayak D, Golani A, Rasool RU, Ahmad SM, Jose J, Kumar R, Gandhi SG, Dinesh Kumar L, Goswami A.

Cell Death Dis. 2019 Jun 13;10(6):467. doi: 10.1038/s41419-019-1690-2.


Pattern Matching for DNA Sequencing Data Using Multiple Bloom Filters.

Najam M, Rasool RU, Ahmad HF, Ashraf U, Malik AW.

Biomed Res Int. 2019 Apr 14;2019:7074387. doi: 10.1155/2019/7074387. eCollection 2019.


Alkyne-azide cycloaddition analogues of dehydrozingerone as potential anti-prostate cancer inhibitors via the PI3K/Akt/NF-kB pathway.

Kumar C, Rasool RU, Iqra Z, Nalli Y, Dutt P, Satti NK, Sharma N, Gandhi SG, Goswami A, Ali A.

Medchemcomm. 2017 Nov 2;8(11):2115-2124. doi: 10.1039/c7md00267j. eCollection 2017 Nov 1.


Dual role of Par-4 in abrogation of EMT and switching on Mesenchymal to Epithelial Transition (MET) in metastatic pancreatic cancer cells.

Katoch A, Suklabaidya S, Chakraborty S, Nayak D, Rasool RU, Sharma D, Mukherjee D, Faheem MM, Kumar A, Sharma PR, Senapati S, Kumar LD, Goswami A.

Mol Carcinog. 2018 Sep;57(9):1102-1115. doi: 10.1002/mc.22828. Epub 2018 May 15.


AKT is indispensable for coordinating Par-4/JNK cross talk in p21 downmodulation during ER stress.

Rasool RU, Nayak D, Chakraborty S, Faheem MM, Rah B, Mahajan P, Gopinath V, Katoch A, Iqra Z, Yousuf SK, Mukherjee D, Kumar LD, Nargotra A, Goswami A.

Oncogenesis. 2017 May 22;6(5):e341. doi: 10.1038/oncsis.2017.41.


Inhibition of Twist1-mediated invasion by Chk2 promotes premature senescence in p53-defective cancer cells.

Nayak D, Kumar A, Chakraborty S, Rasool RU, Amin H, Katoch A, Gopinath V, Mahajan V, Zilla MK, Rah B, Gandhi SG, Ali A, Kumar LD, Goswami A.

Cell Death Differ. 2017 Jul;24(7):1275-1287. doi: 10.1038/cdd.2017.70. Epub 2017 May 12.


Differential regulation of NM23-H1 under hypoxic and serum starvation conditions in metastatic cancer cells and its implication in EMT.

Rasool RU, Nayak D, Chakraborty S, Jamwal VL, Mahajan V, Katoch A, Faheem MM, Iqra Z, Amin H, Gandhi SG, Goswami A.

Eur J Cell Biol. 2017 Mar;96(2):164-171. doi: 10.1016/j.ejcb.2017.01.008. Epub 2017 Feb 4.


A journey beyond apoptosis: new enigma of controlling metastasis by pro-apoptotic Par-4.

Rasool RU, Nayak D, Chakraborty S, Katoch A, Faheem MM, Amin H, Goswami A.

Clin Exp Metastasis. 2016 Dec;33(8):757-764. Epub 2016 Aug 27. Review.


Cristacarpin promotes ER stress-mediated ROS generation leading to premature senescence by activation of p21(waf-1).

Chakraborty S, Rasool RU, Kumar S, Nayak D, Rah B, Katoch A, Amin H, Ali A, Goswami A.

Age (Dordr). 2016 Jun;38(3):62. doi: 10.1007/s11357-016-9922-1. Epub 2016 May 31.


Inhibition of Invasion in Pancreatic Cancer Cells by Conjugate of EPA with β(3,3)-Pip-OH via PI3K/Akt/NF-kB Pathway.

Amin H, Wani NA, Farooq S, Nayak D, Chakraborty S, Shankar S, Rasool RU, Koul S, Goswami A, Rai R.

ACS Med Chem Lett. 2015 Aug 31;6(10):1071-4. doi: 10.1021/acsmedchemlett.5b00257. eCollection 2015 Oct 8.


Design and Synthesis of Antitumor Heck-Coupled Sclareol Analogues: Modulation of BH3 Family Members by SS-12 in Autophagy and Apoptotic Cell Death.

Shakeel-u-Rehman, Rah B, Lone SH, Rasool RU, Farooq S, Nayak D, Chikan NA, Chakraborty S, Behl A, Mondhe DM, Goswami A, Bhat KA.

J Med Chem. 2015 Apr 23;58(8):3432-44. doi: 10.1021/jm501942m. Epub 2015 Apr 9.


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