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Items: 1 to 50 of 55

1.

Early Detection of Peripheral Blood Cell Signature in Children Developing β-Cell Autoimmunity at a Young Age.

Kallionpää H, Somani J, Tuomela S, Ullah U, de Albuquerque R, Lönnberg T, Komsi E, Siljander H, Honkanen J, Härkönen T, Peet A, Tillmann V, Chandra V, Anagandula MK, Frisk G, Otonkoski T, Rasool O, Lund R, Lähdesmäki H, Knip M, Lahesmaa R.

Diabetes. 2019 Oct;68(10):2024-2034. doi: 10.2337/db19-0287. Epub 2019 Jul 16.

PMID:
31311800
2.

Quantitative Proteomics Reveals the Dynamic Protein Landscape during Initiation of Human Th17 Cell Polarization.

Tripathi SK, Välikangas T, Shetty A, Khan MM, Moulder R, Bhosale SD, Komsi E, Salo V, De Albuquerque RS, Rasool O, Galande S, Elo LL, Lahesmaa R.

iScience. 2019 Jan 25;11:334-355. doi: 10.1016/j.isci.2018.12.020. Epub 2018 Dec 26.

3.

Transcriptional Repressor HIC1 Contributes to Suppressive Function of Human Induced Regulatory T Cells.

Ubaid Ullah, Andrabi SBA, Tripathi SK, Dirasantha O, Kanduri K, Rautio S, Gross CC, Lehtimäki S, Bala K, Tuomisto J, Bhatia U, Chakroborty D, Elo LL, Lähdesmäki H, Wiendl H, Rasool O, Lahesmaa R.

Cell Rep. 2018 Feb 20;22(8):2094-2106. doi: 10.1016/j.celrep.2018.01.070.

4.

RNA Polymerase III Subunit POLR3G Regulates Specific Subsets of PolyA+ and SmallRNA Transcriptomes and Splicing in Human Pluripotent Stem Cells.

Lund RJ, Rahkonen N, Malonzo M, Kauko L, Emani MR, Kivinen V, Närvä E, Kemppainen E, Laiho A, Skottman H, Hovatta O, Rasool O, Nykter M, Lähdesmäki H, Lahesmaa R.

Stem Cell Reports. 2017 May 9;8(5):1442-1454. doi: 10.1016/j.stemcr.2017.04.016.

5.

An IFIH1 gene polymorphism associated with risk for autoimmunity regulates canonical antiviral defence pathways in Coxsackievirus infected human pancreatic islets.

Domsgen E, Lind K, Kong L, Hühn MH, Rasool O, van Kuppeveld F, Korsgren O, Lahesmaa R, Flodström-Tullberg M.

Sci Rep. 2016 Dec 21;6:39378. doi: 10.1038/srep39378.

6.

Activation of Plasmacytoid Dendritic Cells in Colon-Draining Lymph Nodes during Citrobacter rodentium Infection Involves Pathogen-Sensing and Inflammatory Pathways Distinct from Conventional Dendritic Cells.

Toivonen R, Kong L, Rasool O, Lund RJ, Lahesmaa R, Hänninen A.

J Immunol. 2016 Jun 1;196(11):4750-9. doi: 10.4049/jimmunol.1600235. Epub 2016 Apr 27.

7.

Comparative analysis of human and mouse transcriptomes of Th17 cell priming.

Tuomela S, Rautio S, Ahlfors H, Öling V, Salo V, Ullah U, Chen Z, Hämälistö S, Tripathi SK, Äijö T, Rasool O, Soueidan H, Wessels L, Stockinger B, Lähdesmäki H, Lahesmaa R.

Oncotarget. 2016 Mar 22;7(12):13416-28. doi: 10.18632/oncotarget.7963.

8.

A validated gene regulatory network and GWAS identifies early regulators of T cell-associated diseases.

Gustafsson M, Gawel DR, Alfredsson L, Baranzini S, Björkander J, Blomgran R, Hellberg S, Eklund D, Ernerudh J, Kockum I, Konstantinell A, Lahesmaa R, Lentini A, Liljenström HR, Mattson L, Matussek A, Mellergård J, Mendez M, Olsson T, Pujana MA, Rasool O, Serra-Musach J, Stenmarker M, Tripathi S, Viitala M, Wang H, Zhang H, Nestor CE, Benson M.

Sci Transl Med. 2015 Nov 11;7(313):313ra178. doi: 10.1126/scitranslmed.aad2722.

9.

The regulation and role of c-FLIP in human Th cell differentiation.

Kyläniemi MK, Kaukonen R, Myllyviita J, Rasool O, Lahesmaa R.

PLoS One. 2014 Jul 14;9(7):e102022. doi: 10.1371/journal.pone.0102022. eCollection 2014.

10.

Gut-adipose tissue axis in hepatic fat accumulation in humans.

Munukka E, Pekkala S, Wiklund P, Rasool O, Borra R, Kong L, Ojanen X, Cheng SM, Roos C, Tuomela S, Alen M, Lahesmaa R, Cheng S.

J Hepatol. 2014 Jul;61(1):132-8. doi: 10.1016/j.jhep.2014.02.020. Epub 2014 Mar 5.

PMID:
24613361
11.

Proviral integration site for Moloney murine leukemia virus (PIM) kinases promote human T helper 1 cell differentiation.

Tahvanainen J, Kyläniemi MK, Kanduri K, Gupta B, Lähteenmäki H, Kallonen T, Rajavuori A, Rasool O, Koskinen PJ, Rao KV, Lähdesmäki H, Lahesmaa R.

J Biol Chem. 2013 Feb 1;288(5):3048-58. doi: 10.1074/jbc.M112.361709. Epub 2012 Dec 3.

12.

RNA-binding protein L1TD1 interacts with LIN28 via RNA and is required for human embryonic stem cell self-renewal and cancer cell proliferation.

Närvä E, Rahkonen N, Emani MR, Lund R, Pursiheimo JP, Nästi J, Autio R, Rasool O, Denessiouk K, Lähdesmäki H, Rao A, Lahesmaa R.

Stem Cells. 2012 Mar;30(3):452-60. doi: 10.1002/stem.1013.

13.

Genome-wide profiling of interleukin-4 and STAT6 transcription factor regulation of human Th2 cell programming.

Elo LL, Järvenpää H, Tuomela S, Raghav S, Ahlfors H, Laurila K, Gupta B, Lund RJ, Tahvanainen J, Hawkins RD, Oresic M, Lähdesmäki H, Rasool O, Rao KV, Aittokallio T, Lahesmaa R.

Immunity. 2010 Jun 25;32(6):852-62. doi: 10.1016/j.immuni.2010.06.011.

14.

SATB1 dictates expression of multiple genes including IL-5 involved in human T helper cell differentiation.

Ahlfors H, Limaye A, Elo LL, Tuomela S, Burute M, Gottimukkala KV, Notani D, Rasool O, Galande S, Lahesmaa R.

Blood. 2010 Sep 2;116(9):1443-53. doi: 10.1182/blood-2009-11-252205. Epub 2010 Jun 3.

15.

High-resolution DNA analysis of human embryonic stem cell lines reveals culture-induced copy number changes and loss of heterozygosity.

Närvä E, Autio R, Rahkonen N, Kong L, Harrison N, Kitsberg D, Borghese L, Itskovitz-Eldor J, Rasool O, Dvorak P, Hovatta O, Otonkoski T, Tuuri T, Cui W, Brüstle O, Baker D, Maltby E, Moore HD, Benvenisty N, Andrews PW, Yli-Harja O, Lahesmaa R.

Nat Biotechnol. 2010 Apr;28(4):371-7. doi: 10.1038/nbt.1615. Epub 2010 Mar 28.

PMID:
20351689
16.

Activating transcription factor 3 is a positive regulator of human IFNG gene expression.

Filén S, Ylikoski E, Tripathi S, West A, Björkman M, Nyström J, Ahlfors H, Coffey E, Rao KV, Rasool O, Lahesmaa R.

J Immunol. 2010 May 1;184(9):4990-9. doi: 10.4049/jimmunol.0903106. Epub 2010 Mar 19.

17.

Quantitative proteomics reveals GIMAP family proteins 1 and 4 to be differentially regulated during human T helper cell differentiation.

Filén JJ, Filén S, Moulder R, Tuomela S, Ahlfors H, West A, Kouvonen P, Kantola S, Björkman M, Katajamaa M, Rasool O, Nyman TA, Lahesmaa R.

Mol Cell Proteomics. 2009 Jan;8(1):32-44. doi: 10.1074/mcp.M800139-MCP200. Epub 2008 Aug 12.

18.

Crystal structure of the major Malassezia sympodialis allergen Mala s 1 reveals a beta-propeller fold: a novel fold among allergens.

Vilhelmsson M, Zargari A, Crameri R, Rasool O, Achour A, Scheynius A, Hallberg BM.

J Mol Biol. 2007 Jun 15;369(4):1079-86. Epub 2007 Apr 12.

PMID:
17481656
19.

Genome-wide identification of novel genes involved in early Th1 and Th2 cell differentiation.

Lund RJ, Löytömäki M, Naumanen T, Dixon C, Chen Z, Ahlfors H, Tuomela S, Tahvanainen J, Scheinin J, Henttinen T, Rasool O, Lahesmaa R.

J Immunol. 2007 Mar 15;178(6):3648-60.

20.

Mala s 12 is a major allergen in patients with atopic eczema and has sequence similarities to the GMC oxidoreductase family.

Zargari A, Selander C, Rasool O, Ghanem M, Gadda G, Crameri R, Scheynius A.

Allergy. 2007 Jun;62(6):695-703. Epub 2007 Feb 20.

PMID:
17313403
21.
22.

Enrichment of nucleofected primary human CD4+ T cells: a novel and efficient method for studying gene function and role in human primary T helper cell differentiation.

Tahvanainen J, Pykäläinen M, Kallonen T, Lähteenmäki H, Rasool O, Lahesmaa R.

J Immunol Methods. 2006 Mar 20;310(1-2):30-9. Epub 2006 Feb 8.

PMID:
16516225
23.

Crystallization and preliminary crystallographic study of the yeast Malassezia sympodialis allergen Mala s 1.

Vilhelmsson M, Hallberg BM, Rasool O, Zargari A, Scheynius A, Achour A.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2006 Feb 1;62(Pt 2):97-9. Epub 2006 Jan 27.

24.

Rational design of hypoallergens applied to the major cat allergen Fel d 1.

Saarne T, Kaiser L, Grönlund H, Rasool O, Gafvelin G, van Hage-Hamsten M.

Clin Exp Allergy. 2005 May;35(5):657-63.

PMID:
15898990
25.

Clarifications on conflicting results published on the amplification of the Mala s 1 allergen gene sequences.

Gaitanis G, Velegraki A, Rasool O, Scheynius A.

J Invest Dermatol. 2005 Feb;124(2):479. No abstract available.

26.

Cloning, expression and characterization of two new IgE-binding proteins from the yeast Malassezia sympodialis with sequence similarities to heat shock proteins and manganese superoxide dismutase.

Andersson A, Rasool O, Schmidt M, Kodzius R, Flückiger S, Zargari A, Crameri R, Scheynius A.

Eur J Biochem. 2004 May;271(10):1885-94. Erratum in: Eur J Biochem. 2004 Dec;271(23-24):4978.

27.

Detection of Mala f and Mala s allergen sequences within the genus Malassezia.

Andersson A, Scheynius A, Rasool O.

Med Mycol. 2003 Dec;41(6):479-85.

PMID:
14725321
28.

Cloning and characterisation of two IgE-binding proteins, homologous to tropomyosin and alpha-tubulin, from the mite Lepidoglyphus destructor.

Saarne T, Kaiser L, Rasool O, Huecas S, van Hage-Hamsten M, Gafvelin G.

Int Arch Allergy Immunol. 2003 Apr;130(4):258-65.

PMID:
12740526
29.

Lep d 2 polymorphisms in wild and cultured Lepidoglyphus destructor mites.

Kaiser L, Gafvelin G, Johansson E, van Hage-Hamsten M, Rasool O.

Eur J Biochem. 2003 Feb;270(4):646-53.

30.

Deletion of the Ink4-locus (the p16ink4a, p14ARF and p15ink4b genes) predicts relapse in children with ALL treated according to the Nordic protocols NOPHO-86 and NOPHO-92.

Calero Moreno TM, Gustafsson G, Garwicz S, Grandér D, Jonmundsson GK, Frost BM, Mäkipernaa A, Rasool O, Savolainen ER, Schmiegelow K, Söderhäll S, Vettenranta K, Wesenberg F, Einhorn S, Heyman M.

Leukemia. 2002 Oct;16(10):2037-45.

31.

Immunological characterization of Echinococcus granulosus cyclophilin, an allergen reactive with IgE and IgG4 from patients with cystic echinococcosis.

Ortona E, Vaccari S, Margutti P, Delunardo F, Rigano R, Profumo E, Buttari B, Rasool O, Teggi A, Siracusano A.

Clin Exp Immunol. 2002 Apr;128(1):124-30.

32.

Cloning of three new allergens from the dust mite Lepidoglyphus destructor using phage surface display technology.

Eriksson TL, Rasool O, Huecas S, Whitley P, Crameri R, Appenzeller U, Gafvelin G, van Hage-Hamsten M.

Eur J Biochem. 2001 Jan;268(2):287-94.

33.

Cloning, characterization and expression of complete coding sequences of three IgE binding Malassezia furfur allergens, Mal f 7, Mal f 8 and Mal f 9.

Rasool O, Zargari A, Almqvist J, Eshaghi H, Whitley P, Scheynius A.

Eur J Biochem. 2000 Jul;267(14):4355-61.

34.

A cosmid and cDNA fine physical map of a human chromosome 13q14 region frequently lost in B-cell chronic lymphocytic leukemia and identification of a new putative tumor suppressor gene, Leu5.

Kapanadze B, Kashuba V, Baranova A, Rasool O, van Everdink W, Liu Y, Syomov A, Corcoran M, Poltaraus A, Brodyansky V, Syomova N, Kazakov A, Ibbotson R, van den Berg A, Gizatullin R, Fedorova L, Sulimova G, Zelenin A, Deaven L, Lehrach H, Grander D, Buys C, Oscier D, Zabarovsky ER, Einhorn S, Yankovsky N.

FEBS Lett. 1998 Apr 17;426(2):266-70.

35.

6q deletions in acute lymphoblastic leukemia and non-Hodgkin's lymphomas.

Merup M, Moreno TC, Heyman M, Rönnberg K, Grandér D, Detlofsson R, Rasool O, Liu Y, Söderhäll S, Juliusson G, Gahrton G, Einhorn S.

Blood. 1998 May 1;91(9):3397-400.

36.

A FISH cosmid 'cocktail' for detection of 13q deletions in chronic lymphocytic leukaemia--comparison with cytogenetics and Southern hybridization.

Merup M, Jansson M, Corcoran M, Liu Y, Wu X, Rasool O, Stellan B, Hermansson M, Juliusson G, Gahrton G, Einhorn S.

Leukemia. 1998 May;12(5):705-9.

37.

Detailed molecular delineation of 13q14.3 loss in B-cell chronic lymphocytic leukemia.

Corcoran MM, Rasool O, Liu Y, Iyengar A, Grander D, Ibbotson RE, Merup M, Wu X, Brodyansky V, Gardiner AC, Juliusson G, Chapman RM, Ivanova G, Tiller M, Gahrton G, Yankovsky N, Zabarovsky E, Oscier DG, Einhorn S.

Blood. 1998 Feb 15;91(4):1382-90.

38.

Cloning of two candidate tumor suppressor genes within a 10 kb region on chromosome 13q14, frequently deleted in chronic lymphocytic leukemia.

Liu Y, Corcoran M, Rasool O, Ivanova G, Ibbotson R, Grandér D, Iyengar A, Baranova A, Kashuba V, Merup M, Wu X, Gardiner A, Mullenbach R, Poltaraus A, Hultström AL, Juliusson G, Chapman R, Tiller M, Cotter F, Gahrton G, Yankovsky N, Zabarovsky E, Einhorn S, Oscier D.

Oncogene. 1997 Nov 13;15(20):2463-73.

39.

Inverse correlation between loss of heterozygosity of the short arm of chromosome 12 and p15ink4B/p16ink4 gene inactivation in childhood acute lymphoblastic leukaemia.

Heyman M, Calero Moreno T, Liu Y, Grandér D, Rasool O, Borgonova-Brandter L, Merup M, Söderhäll S, Einhorn S.

Br J Haematol. 1997 Jul;98(1):147-50.

PMID:
9233578
40.

Amplification of multiple regions of chromosome 12, including 12q13-15, in chronic lymphocytic leukaemia.

Merup M, Juliusson G, Wu X, Jansson M, Stellan B, Rasool O, Röijer E, Stenman G, Gahrton G, Einhorn S.

Eur J Haematol. 1997 Mar;58(3):174-80.

PMID:
9150711
41.

A T cell lymphoblastic lymphoma patient with two malignant cell populations carrying different 9p deletions including the p16INK4 and p15INK4B genes: Clinical response to interferon-alpha therapy in one of the subclones.

Heyman M, Nordgren A, Jeddi-Tehrani M, Rasool O, Liu Y, Grander D, Ost A, Wallberg B, Johansson B.

Leukemia. 1996 May;10(5):909-17. No abstract available.

PMID:
8656689
42.

p16INK4/p15INK4B gene inactivation is a frequent event in malignant T-cell lines.

Borgonovo Brandter L, Heyman M, Rasool O, Liu Y, Grandér D, Einhorn S.

Eur J Haematol. 1996 May;56(5):313-8.

PMID:
8641406
43.

Prognostic importance of p15INK4B and p16INK4 gene inactivation in childhood acute lymphocytic leukemia.

Heyman M, Rasool O, Borgonovo Brandter L, Liu Y, Grandér D, Söderhäll S, Gustavsson G, Einhorn S.

J Clin Oncol. 1996 May;14(5):1512-20.

PMID:
8622065
44.

Exclusive p15INK4B gene deletions in acute lymphocytic leukemia include the E1 beta exon of the p16INK4 gene.

Heyman M, Rasool O, Brandter LB, Liu Y, Grandér D, Einhorn S, Söderhäll S.

Blood. 1996 Feb 15;87(4):1657-8. No abstract available.

45.

Effect of N-acetylcysteine(NAC) treatment on HIV-1 infection: a double-blind placebo-controlled trial.

Akerlund B, Jarstrand C, Lindeke B, Sönnerborg A, Akerblad AC, Rasool O.

Eur J Clin Pharmacol. 1996;50(6):457-61.

PMID:
8858271
46.

13q deletions in lymphoid malignancies.

Liu Y, Hermanson M, Grandér D, Merup M, Wu X, Heyman M, Rasool O, Juliusson G, Gahrton G, Detlofsson R, Nikiforova N, Buys C, Söderhäll S, Yankovsky N, Zabarovsky E, Einhorn S.

Blood. 1995 Sep 1;86(5):1911-5.

47.

Effect of surfactant on nitroblue tetrazolium reduction of polymorphonuclear leucocytes stimulated with type Ia group B streptococci.

Herting E, Jarstrand C, Rasool O, Curstedt T, Håkansson S, Robertson B.

Acta Paediatr. 1995 Aug;84(8):922-6.

PMID:
7488818
48.

p15ink4B and p16ink4 gene inactivation in acute lymphocytic leukemia.

Rasool O, Heyman M, Brandter LB, Liu Y, Grandér D, Söderhäll S, Einhorn S.

Blood. 1995 Jun 15;85(12):3431-6.

49.

Sequence variability of a prolonged tetranucleotide repeat.

Liu Y, Rasool O, Grandér D, Lindblom A, Einhorn S.

Hum Mol Genet. 1995 Apr;4(4):727-9.

PMID:
7633423
50.

Experimental neonatal group B streptococcal pneumonia: effect of a modified porcine surfactant on bacterial proliferation in ventilated near-term rabbits.

Herting E, Jarstrand C, Rasool O, Curstedt T, Sun B, Robertson B.

Pediatr Res. 1994 Dec;36(6):784-91.

PMID:
7898987

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