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Items: 1 to 50 of 134

1.

MERTK Acts as a Costimulatory Receptor on Human CD8+ T Cells.

Peeters MJW, Dulkeviciute D, Draghi A, Ritter C, Rahbech A, Skadborg SK, Seremet T, Carnaz Simões AM, Martinenaite E, Halldórsdóttir HR, Andersen MH, Olofsson GH, Svane IM, Rasmussen LJ, Met Ö, Becker JC, Donia M, Desler C, Thor Straten P.

Cancer Immunol Res. 2019 Sep;7(9):1472-1484. doi: 10.1158/2326-6066.CIR-18-0841. Epub 2019 Jul 2.

PMID:
31266785
2.

Early Discharge from the Emergency Department Based on Soluble Urokinase Plasminogen Activator Receptor (suPAR) Levels: A TRIAGE III Substudy.

Schultz M, Rasmussen LJH, Høi-Hansen T, Kjøller E, Jensen BN, Lind MN, Ravn L, Kallemose T, Lange T, Køber L, Rasmussen LS, Eugen-Olsen J, Iversen KK.

Dis Markers. 2019 May 19;2019:3403549. doi: 10.1155/2019/3403549. eCollection 2019.

3.

Turtles maintain mitochondrial integrity but reduce mitochondrial respiratory capacity in the heart after cold acclimation and anoxia.

Bundgaard A, Qvortrup K, Rasmussen LJ, Fago A.

J Exp Biol. 2019 Jun 10;222(Pt 11). pii: jeb200410. doi: 10.1242/jeb.200410.

PMID:
31097599
4.

Risk assessment models for potential use in the emergency department have lower predictive ability in older patients compared to the middle-aged for short-term mortality - a retrospective cohort study.

Schultz M, Rasmussen LJH, Carlson N, Hasselbalch RB, Jensen BN, Usinger L, Eugen-Olsen J, Torp-Pedersen C, Rasmussen LS, Iversen KK.

BMC Geriatr. 2019 May 16;19(1):134. doi: 10.1186/s12877-019-1154-7.

5.

From Powerhouse to Perpetrator-Mitochondria in Health and Disease.

Fakouri NB, Hansen TL, Desler C, Anugula S, Rasmussen LJ.

Biology (Basel). 2019 May 11;8(2). pii: E35. doi: 10.3390/biology8020035. Review.

6.

Mitochondrial oxidative phosphorylation capacity of cryopreserved cells.

Lauridsen PE, Rasmussen LJ, Desler C.

Mitochondrion. 2019 Jul;47:47-53. doi: 10.1016/j.mito.2019.04.011. Epub 2019 Apr 30.

PMID:
31051261
7.

Availability of suPAR in emergency departments may improve risk stratification: a secondary analysis of the TRIAGE III trial.

Schultz M, Rasmussen LJH, Kallemose T, Kjøller E, Lind MN, Ravn L, Lange T, Køber L, Rasmussen LS, Eugen-Olsen J, Iversen K.

Scand J Trauma Resusc Emerg Med. 2019 Apr 11;27(1):43. doi: 10.1186/s13049-019-0621-7.

8.

Healthy lifestyles reduce suPAR and mortality in a Danish general population study.

Haupt TH, Rasmussen LJH, Kallemose T, Ladelund S, Andersen O, Pisinger C, Eugen-Olsen J.

Immun Ageing. 2019 Jan 22;16:1. doi: 10.1186/s12979-018-0141-8. eCollection 2019.

9.

Soluble urokinase plasminogen activator receptor is linearly associated with dietary quality and predicts mortality.

Törnkvist PBS, Haupt TH, Rasmussen LJH, Ladelund S, Toft U, Pisinger C, Eugen-Olsen J.

Br J Nutr. 2019 Mar;121(6):699-708. doi: 10.1017/S0007114518003720. Epub 2019 Jan 10.

PMID:
30626457
10.

A functional assay-based procedure to classify mismatch repair gene variants in Lynch syndrome.

Drost M, Tiersma Y, Thompson BA, Frederiksen JH, Keijzers G, Glubb D, Kathe S, Osinga J, Westers H, Pappas L, Boucher KM, Molenkamp S, Zonneveld JB, van Asperen CJ, Goldgar DE, Wallace SS, Sijmons RH, Spurdle AB, Rasmussen LJ, Greenblatt MS, de Wind N, Tavtigian SV.

Genet Med. 2019 Jul;21(7):1486-1496. doi: 10.1038/s41436-018-0372-2. Epub 2018 Dec 3.

PMID:
30504929
11.

Soluble Urokinase Plasminogen Activator Receptor (suPAR) as an Added Predictor to Existing Preoperative Risk Assessments.

Alstrup M, Meyer J, Schultz M, Rasmussen LJH, Rasmussen LS, Køber L, Forberg JL, Eugen-Olsen J, Iversen K.

World J Surg. 2019 Mar;43(3):780-790. doi: 10.1007/s00268-018-4841-1.

PMID:
30390135
12.

Combining National Early Warning Score With Soluble Urokinase Plasminogen Activator Receptor (suPAR) Improves Risk Prediction in Acute Medical Patients: A Registry-Based Cohort Study.

Rasmussen LJH, Ladelund S, Haupt TH, Ellekilde GE, Eugen-Olsen J, Andersen O.

Crit Care Med. 2018 Dec;46(12):1961-1968. doi: 10.1097/CCM.0000000000003441.

13.

Use of the prognostic biomarker suPAR in the emergency department improves risk stratification but has no effect on mortality: a cluster-randomized clinical trial (TRIAGE III).

Schultz M, Rasmussen LJH, Andersen MH, Stefansson JS, Falkentoft AC, Alstrup M, Sandø A, Holle SLK, Meyer J, Törnkvist PBS, Høi-Hansen T, Kjøller E, Jensen BN, Lind M, Ravn L, Kallemose T, Lange T, Køber L, Rasmussen LS, Eugen-Olsen J, Iversen KK.

Scand J Trauma Resusc Emerg Med. 2018 Aug 28;26(1):69. doi: 10.1186/s13049-018-0539-5.

14.

A Ketogenic Diet Improves Mitochondrial Biogenesis and Bioenergetics via the PGC1α-SIRT3-UCP2 Axis.

Hasan-Olive MM, Lauritzen KH, Ali M, Rasmussen LJ, Storm-Mathisen J, Bergersen LH.

Neurochem Res. 2019 Jan;44(1):22-37. doi: 10.1007/s11064-018-2588-6. Epub 2018 Jul 19.

PMID:
30027365
15.

Soluble Urokinase Plasminogen Activator Receptor (suPAR) as a Predictor of Incident Atrial Fibrillation.

Westin O, Rasmussen LJH, Andersen O, Buch E, Olsen JE, Friberg J.

J Atr Fibrillation. 2018 Apr 30;10(6):1801. doi: 10.4022/jafib.1801. eCollection 2018 Apr.

16.

The inhibitors of soluble adenylate cyclase 2-OHE, KH7, and bithionol compromise mitochondrial ATP production by distinct mechanisms.

Jakobsen E, Lange SC, Andersen JV, Desler C, Kihl HF, Hohnholt MC, Stridh MH, Rasmussen LJ, Waagepetersen HS, Bak LK.

Biochem Pharmacol. 2018 Sep;155:92-101. doi: 10.1016/j.bcp.2018.06.023. Epub 2018 Jun 22.

PMID:
29940175
17.

Soluble urokinase plasminogen activator receptor predicts mortality in exacerbated COPD.

Godtfredsen NS, Jørgensen DV, Marsaa K, Ulrik CS, Andersen O, Eugen-Olsen J, Rasmussen LJH.

Respir Res. 2018 May 21;19(1):97. doi: 10.1186/s12931-018-0803-2.

18.

Cumulative childhood risk is associated with a new measure of chronic inflammation in adulthood.

Rasmussen LJH, Moffitt TE, Eugen-Olsen J, Belsky DW, Danese A, Harrington H, Houts RM, Poulton R, Sugden K, Williams B, Caspi A.

J Child Psychol Psychiatry. 2019 Feb;60(2):199-208. doi: 10.1111/jcpp.12928. Epub 2018 May 9.

PMID:
29741788
19.

Author Correction: Rev1 contributes to proper mitochondrial function via the PARP-NAD+-SIRT1-PGC1α axis.

Fakouri NB, Durhuus JA, Regnell CE, Angleys M, Desler C, Hasan-Olive MM, Martín-Pardillos A, Tsaalbi-Shtylik A, Thomsen K, Lauritzen M, Bohr VA, de Wind N, Bergersen LH, Rasmussen LJ.

Sci Rep. 2018 Mar 6;8(1):4245. doi: 10.1038/s41598-018-20586-9.

20.

suPAR is associated with risk of future acute surgery and post-operative mortality in acutely admitted medical patients.

Meyer J, Alstrup M, Rasmussen LJH, Schultz M, Ladelund S, Haupt TH, Tingleff J, Iversen K, Eugen-Olsen J.

Scand J Trauma Resusc Emerg Med. 2018 Feb 1;26(1):11. doi: 10.1186/s13049-018-0478-1.

21.

Initial brain aging: heterogeneity of mitochondrial size is associated with decline in complex I-linked respiration in cortex and hippocampus.

Thomsen K, Yokota T, Hasan-Olive MM, Sherazi N, Fakouri NB, Desler C, Regnell CE, Larsen S, Rasmussen LJ, Dela F, Bergersen LH, Lauritzen M.

Neurobiol Aging. 2018 Jan;61:215-224. doi: 10.1016/j.neurobiolaging.2017.08.004. Epub 2017 Aug 12.

PMID:
29031832
22.

Rev1 contributes to proper mitochondrial function via the PARP-NAD+-SIRT1-PGC1α axis.

Fakouri NB, Durhuus JA, Regnell CE, Angleys M, Desler C, Hasan-Olive MM, Martín-Pardillos A, Tsaalbi-Shtylik A, Thomsen K, Lauritzen M, Bohr VA, de Wind N, Bergersen LH, Rasmussen LJ.

Sci Rep. 2017 Oct 2;7(1):12480. doi: 10.1038/s41598-017-12662-3. Erratum in: Sci Rep. 2018 Mar 6;8(1):4245.

23.

Human DNA polymerase delta double-mutant D316A;E318A interferes with DNA mismatch repair in vitro.

Liu D, Frederiksen JH, Liberti SE, Lützen A, Keijzers G, Pena-Diaz J, Rasmussen LJ.

Nucleic Acids Res. 2017 Sep 19;45(16):9427-9440. doi: 10.1093/nar/gkx611.

24.

DNA mismatch repair and its many roles in eukaryotic cells.

Liu D, Keijzers G, Rasmussen LJ.

Mutat Res. 2017 Jul;773:174-187. doi: 10.1016/j.mrrev.2017.07.001. Epub 2017 Jul 9. Review.

PMID:
28927527
25.

Genomic and functional integrity of the hematopoietic system requires tolerance of oxidative DNA lesions.

Martín-Pardillos A, Tsaalbi-Shtylik A, Chen S, Lazare S, van Os RP, Dethmers-Ausema A, Fakouri NB, Bosshard M, Aprigliano R, van Loon B, Salvatori DCF, Hashimoto K, Dingemanse-van der Spek C, Moriya M, Rasmussen LJ, de Haan G, Raaijmakers MHGP, de Wind N.

Blood. 2017 Sep 28;130(13):1523-1534. doi: 10.1182/blood-2017-01-764274. Epub 2017 Aug 21. Erratum in: Blood. 2018 Feb 8;131(6):710.

26.

Bacterial infection increases risk of carcinogenesis by targeting mitochondria.

Strickertsson JAB, Desler C, Rasmussen LJ.

Semin Cancer Biol. 2017 Dec;47:95-100. doi: 10.1016/j.semcancer.2017.07.003. Epub 2017 Jul 25. Review.

PMID:
28754330
27.

The Role of Mitochondrial Dysfunction in the Progression of Alzheimer's Disease.

Desler C, Lillenes MS, Tønjum T, Rasmussen LJ.

Curr Med Chem. 2018;25(40):5578-5587. doi: 10.2174/0929867324666170616110111. Review.

28.

Involvement of the DNA mismatch repair system in cisplatin sensitivity of testicular germ cell tumours.

Rudolph C, Melau C, Nielsen JE, Vile Jensen K, Liu D, Pena-Diaz J, Rajpert-De Meyts E, Rasmussen LJ, Jørgensen A.

Cell Oncol (Dordr). 2017 Aug;40(4):341-355. doi: 10.1007/s13402-017-0326-8. Epub 2017 May 23.

PMID:
28536927
29.

Predicting the impact of Lynch syndrome-causing missense mutations from structural calculations.

Nielsen SV, Stein A, Dinitzen AB, Papaleo E, Tatham MH, Poulsen EG, Kassem MM, Rasmussen LJ, Lindorff-Larsen K, Hartmann-Petersen R.

PLoS Genet. 2017 Apr 19;13(4):e1006739. doi: 10.1371/journal.pgen.1006739. eCollection 2017 Apr.

30.

Inflammatory biomarkers and cancer: CRP and suPAR as markers of incident cancer in patients with serious nonspecific symptoms and signs of cancer.

Rasmussen LJH, Schultz M, Gaardsting A, Ladelund S, Garred P, Iversen K, Eugen-Olsen J, Helms M, David KP, Kjaer A, Lebech AM, Kronborg G.

Int J Cancer. 2017 Jul 1;141(1):191-199. doi: 10.1002/ijc.30732. Epub 2017 Apr 24.

31.

Disturbed mitochondrial function restricts glutamate uptake in the human Müller glia cell line, MIO-M1.

Vohra R, Gurubaran IS, Henriksen U, Bergersen LH, Rasmussen LJ, Desler C, Skytt DM, Kolko M.

Mitochondrion. 2017 Sep;36:52-59. doi: 10.1016/j.mito.2017.02.003. Epub 2017 Feb 6.

PMID:
28185966
32.

A Novel Rrm3 Function in Restricting DNA Replication via an Orc5-Binding Domain Is Genetically Separable from Rrm3 Function as an ATPase/Helicase in Facilitating Fork Progression.

Syed S, Desler C, Rasmussen LJ, Schmidt KH.

PLoS Genet. 2016 Dec 6;12(12):e1006451. doi: 10.1371/journal.pgen.1006451. eCollection 2016 Dec.

33.

Interventions for age-related diseases: Shifting the paradigm.

Figueira I, Fernandes A, Mladenovic Djordjevic A, Lopez-Contreras A, Henriques CM, Selman C, Ferreiro E, Gonos ES, Trejo JL, Misra J, Rasmussen LJ, Xapelli S, Ellam T, Bellantuono I.

Mech Ageing Dev. 2016 Dec;160:69-92. doi: 10.1016/j.mad.2016.09.009. Epub 2016 Sep 29. Review.

34.

Soluble urokinase plasminogen activator receptor (suPAR) in acute care: a strong marker of disease presence and severity, readmission and mortality. A retrospective cohort study.

Rasmussen LJ, Ladelund S, Haupt TH, Ellekilde G, Poulsen JH, Iversen K, Eugen-Olsen J, Andersen O.

Emerg Med J. 2016 Nov;33(11):769-775. doi: 10.1136/emermed-2015-205444. Epub 2016 Sep 2.

35.

Exonuclease 1 and its versatile roles in DNA repair.

Keijzers G, Liu D, Rasmussen LJ.

Crit Rev Biochem Mol Biol. 2016 Nov/Dec;51(6):440-451. doi: 10.1080/10409238.2016.1215407. Epub 2016 Aug 5. Review.

PMID:
27494243
36.

RECQL4 Promotes DNA End Resection in Repair of DNA Double-Strand Breaks.

Lu H, Shamanna RA, Keijzers G, Anand R, Rasmussen LJ, Cejka P, Croteau DL, Bohr VA.

Cell Rep. 2016 Jun 28;16(1):161-173. doi: 10.1016/j.celrep.2016.05.079. Epub 2016 Jun 16.

37.

Acquired Localized Cutis Laxa due to Increased Elastin Turnover.

Nygaard RH, Maynard S, Schjerling P, Kjaer M, Qvortrup K, Bohr VA, Rasmussen LJ, Jemec GB, Heidenheim M.

Case Rep Dermatol. 2016 Feb 13;8(1):42-51. doi: 10.1159/000443696. eCollection 2016 Jan-Apr.

38.

Oxidative Stress-Induced Dysfunction of Müller Cells During Starvation.

Toft-Kehler AK, Gurubaran IS, Desler C, Rasmussen LJ, Skytt DM, Kolko M.

Invest Ophthalmol Vis Sci. 2016 May 1;57(6):2721-8. doi: 10.1167/iovs.16-19275.

PMID:
27196320
39.

LIFESTAT - Living with statins: An interdisciplinary project on the use of statins as a cholesterol-lowering treatment and for cardiovascular risk reduction.

Christensen CL, Wulff Helge J, Krasnik A, Kriegbaum M, Rasmussen LJ, Hickson ID, Liisberg KB, Oxlund B, Bruun B, Lau SR, Olsen MN, Andersen JS, Heltberg AS, Kuhlman AB, Morville TH, Dohlmann TL, Larsen S, Dela F.

Scand J Public Health. 2016 Jul;44(5):534-9. doi: 10.1177/1403494816636304. Epub 2016 Mar 3.

PMID:
26939591
40.

Approaches to diagnose DNA mismatch repair gene defects in cancer.

Peña-Diaz J, Rasmussen LJ.

DNA Repair (Amst). 2016 Feb;38:147-154. doi: 10.1016/j.dnarep.2015.11.022. Epub 2015 Dec 8. Review.

PMID:
26708048
41.

Letters to the Editor: Genetic polymorphism and soluble urokinase plasminogen activator receptor regulation.

Rasmussen LJ, Haupt TH, Andersen O, Eugen-Olsen J.

FASEB J. 2015 Dec;29(12):4757-8. doi: 10.1096/fj.15-1201LTE. No abstract available.

PMID:
26626707
42.

Defective mitochondrial respiration, altered dNTP pools and reduced AP endonuclease 1 activity in peripheral blood mononuclear cells of Alzheimer's disease patients.

Maynard S, Hejl AM, Dinh TS, Keijzers G, Hansen ÅM, Desler C, Moreno-Villanueva M, Bürkle A, Rasmussen LJ, Waldemar G, Bohr VA.

Aging (Albany NY). 2015 Oct;7(10):793-815.

43.

Increased deoxythymidine triphosphate levels is a feature of relative cognitive decline.

Desler C, Frederiksen JH, Angleys M, Maynard S, Keijzers G, Fagerlund B, Mortensen EL, Osler M, Lauritzen M, Bohr VA, Rasmussen LJ.

Mitochondrion. 2015 Nov;25:34-7. doi: 10.1016/j.mito.2015.09.002. Epub 2015 Sep 25.

44.

Soluble urokinase plasminogen activator receptor (suPAR) is a novel, independent predictive marker of myocardial infarction in HIV-1-infected patients: a nested case-control study.

Rasmussen LJ, Knudsen A, Katzenstein TL, Gerstoft J, Obel N, Jørgensen NR, Kronborg G, Benfield T, Kjaer A, Eugen-Olsen J, Lebech AM.

HIV Med. 2016 May;17(5):350-7. doi: 10.1111/hiv.12315. Epub 2015 Sep 14.

45.

Human exonuclease 1 (EXO1) activity characterization and its function on flap structures.

Keijzers G, Bohr VA, Rasmussen LJ.

Biosci Rep. 2015 Apr 25;35(3). pii: e00206. doi: 10.1042/BSR20150058.

46.

Impaired dynamics and function of mitochondria caused by mtDNA toxicity leads to heart failure.

Lauritzen KH, Kleppa L, Aronsen JM, Eide L, Carlsen H, Haugen ØP, Sjaastad I, Klungland A, Rasmussen LJ, Attramadal H, Storm-Mathisen J, Bergersen LH.

Am J Physiol Heart Circ Physiol. 2015 Aug 1;309(3):H434-49. doi: 10.1152/ajpheart.00253.2014. Epub 2015 Jun 8.

47.

Integrin β1, Osmosensing, and Chemoresistance in Mouse Ehrlich Carcinoma Cells.

Sørensen BH, Rasmussen LJ, Broberg BS, Klausen TK, Sauter DP, Lambert IH, Aspberg A, Hoffmann EK.

Cell Physiol Biochem. 2015;36(1):111-32. doi: 10.1159/000374057. Epub 2015 Apr 27.

48.

Increased Rrm2 gene dosage reduces fragile site breakage and prolongs survival of ATR mutant mice.

Lopez-Contreras AJ, Specks J, Barlow JH, Ambrogio C, Desler C, Vikingsson S, Rodrigo-Perez S, Green H, Rasmussen LJ, Murga M, Nussenzweig A, Fernandez-Capetillo O.

Genes Dev. 2015 Apr 1;29(7):690-5. doi: 10.1101/gad.256958.114.

49.

Risk factors associated with serum levels of the inflammatory biomarker soluble urokinase plasminogen activator receptor in a general population.

Haupt TH, Kallemose T, Ladelund S, Rasmussen LJ, Thorball CW, Andersen O, Pisinger C, Eugen-Olsen J.

Biomark Insights. 2014 Dec 16;9:91-100. doi: 10.4137/BMI.S19876. eCollection 2014.

50.

The challenges of human population ageing.

Sander M, Oxlund B, Jespersen A, Krasnik A, Mortensen EL, Westendorp RG, Rasmussen LJ.

Age Ageing. 2015 Mar;44(2):185-7. doi: 10.1093/ageing/afu189. Epub 2014 Dec 1.

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