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Items: 1 to 50 of 169

1.

Stem Cell Businesses and Right to Try Laws.

Sipp D, Turner L, Rasko JEJ.

Cell Stem Cell. 2019 Sep 5;25(3):304-305. doi: 10.1016/j.stem.2019.08.012. No abstract available.

PMID:
31491393
2.

EGF-activated PI3K/Akt signalling coordinates leucine uptake by regulating LAT3 expression in prostate cancer.

Zhang BK, Moran AM, Bailey CG, Rasko JEJ, Holst J, Wang Q.

Cell Commun Signal. 2019 Jul 25;17(1):83. doi: 10.1186/s12964-019-0400-0.

3.

Exosomal lncRNAs and cancer: connecting the missing links.

Naderi-Meshkin H, Lai X, Amirkhah R, Vera J, Rasko JEJ, Schmitz U.

Bioinformatics. 2019 Jan 15;35(2):352-360. doi: 10.1093/bioinformatics/bty527.

PMID:
30649349
4.

CTCF Expression is Essential for Somatic Cell Viability and Protection Against Cancer.

Bailey CG, Metierre C, Feng Y, Baidya K, Filippova GN, Loukinov DI, Lobanenkov VV, Semaan C, Rasko JE.

Int J Mol Sci. 2018 Nov 30;19(12). pii: E3832. doi: 10.3390/ijms19123832.

5.

DNA methylation/hydroxymethylation regulate gene expression and alternative splicing during terminal granulopoiesis.

Gao D, Pinello N, Nguyen TV, Thoeng A, Nagarajah R, Holst J, Rasko JE, Wong JJ.

Epigenomics. 2019 Jan;11(1):95-109. doi: 10.2217/epi-2018-0050. Epub 2018 Nov 14.

PMID:
30427216
6.

Cell, tissue and gene products with marketing authorization in 2018 worldwide.

Cuende N, Rasko JEJ, Koh MBC, Dominici M, Ikonomou L.

Cytotherapy. 2018 Nov;20(11):1401-1413. doi: 10.1016/j.jcyt.2018.09.010. Epub 2018 Oct 24.

7.

Spred negatively regulates lens growth by modulating epithelial cell proliferation and fiber differentiation.

Susanto A, Zhao G, Wazin F, Feng Y, Rasko JEJ, Bailey CG, Lovicu FJ.

Exp Eye Res. 2019 Jan;178:160-175. doi: 10.1016/j.exer.2018.09.019. Epub 2018 Oct 2.

PMID:
30290165
8.

Direct and rapid identification of T315I-Mutated BCR-ABL expressing leukemic cells using infrared microspectroscopy.

Sandt C, Feraud O, Bonnet ML, Desterke C, Khedhir R, Flamant S, Bailey CG, Rasko JEJ, Dumas P, Bennaceur-Griscelli A, Turhan AG.

Biochem Biophys Res Commun. 2018 Sep 10;503(3):1861-1867. doi: 10.1016/j.bbrc.2018.07.127. Epub 2018 Jul 26.

PMID:
30057314
9.

Guidelines for whole genome bisulphite sequencing of intact and FFPET DNA on the Illumina HiSeq X Ten.

Nair SS, Luu PL, Qu W, Maddugoda M, Huschtscha L, Reddel R, Chenevix-Trench G, Toso M, Kench JG, Horvath LG, Hayes VM, Stricker PD, Hughes TP, White DL, Rasko JEJ, Wong JJ, Clark SJ.

Epigenetics Chromatin. 2018 May 28;11(1):24. doi: 10.1186/s13072-018-0194-0.

10.

Identifying microRNA determinants of human myelopoiesis.

Rajasekhar M, Schmitz U, Flamant S, Wong JJ, Bailey CG, Ritchie W, Holst J, Rasko JEJ.

Sci Rep. 2018 May 8;8(1):7264. doi: 10.1038/s41598-018-24203-7.

11.

Gene Therapy in Patients with Transfusion-Dependent β-Thalassemia.

Thompson AA, Walters MC, Kwiatkowski J, Rasko JEJ, Ribeil JA, Hongeng S, Magrin E, Schiller GJ, Payen E, Semeraro M, Moshous D, Lefrere F, Puy H, Bourget P, Magnani A, Caccavelli L, Diana JS, Suarez F, Monpoux F, Brousse V, Poirot C, Brouzes C, Meritet JF, Pondarré C, Beuzard Y, Chrétien S, Lefebvre T, Teachey DT, Anurathapan U, Ho PJ, von Kalle C, Kletzel M, Vichinsky E, Soni S, Veres G, Negre O, Ross RW, Davidson D, Petrusich A, Sandler L, Asmal M, Hermine O, De Montalembert M, Hacein-Bey-Abina S, Blanche S, Leboulch P, Cavazzana M.

N Engl J Med. 2018 Apr 19;378(16):1479-1493. doi: 10.1056/NEJMoa1705342.

12.

No Vacillation on HPV Vaccination.

Sipp D, Frazer IH, Rasko JEJ.

Cell. 2018 Mar 8;172(6):1163-1167. doi: 10.1016/j.cell.2018.02.045.

13.

We skip to work: alternative splicing in normal and malignant myelopoiesis.

Wong ACH, Rasko JEJ, Wong JJ.

Leukemia. 2018 May;32(5):1081-1093. doi: 10.1038/s41375-018-0021-4. Epub 2018 Jan 30. Review.

PMID:
29467484
14.

Diversity of transcripts emanating from protein-coding genes.

Rasko JEJ, Preiss T.

Semin Cell Dev Biol. 2018 Mar;75:1-2. doi: 10.1016/j.semcdb.2018.01.011. Epub 2018 Feb 1. No abstract available.

PMID:
29391207
15.

Hemophilia B Gene Therapy with a High-Specific-Activity Factor IX Variant.

George LA, Sullivan SK, Giermasz A, Rasko JEJ, Samelson-Jones BJ, Ducore J, Cuker A, Sullivan LM, Majumdar S, Teitel J, McGuinn CE, Ragni MV, Luk AY, Hui D, Wright JF, Chen Y, Liu Y, Wachtel K, Winters A, Tiefenbacher S, Arruda VR, van der Loo JCM, Zelenaia O, Takefman D, Carr ME, Couto LB, Anguela XM, High KA.

N Engl J Med. 2017 Dec 7;377(23):2215-2227. doi: 10.1056/NEJMoa1708538.

16.

First Approved Kinase Inhibitor for AML.

Rasko JEJ, Hughes TP.

Cell. 2017 Nov 16;171(5):981. doi: 10.1016/j.cell.2017.11.007.

17.

Intron retention enhances gene regulatory complexity in vertebrates.

Schmitz U, Pinello N, Jia F, Alasmari S, Ritchie W, Keightley MC, Shini S, Lieschke GJ, Wong JJ, Rasko JEJ.

Genome Biol. 2017 Nov 16;18(1):216. doi: 10.1186/s13059-017-1339-3.

18.

Implicit hype? Representations of platelet rich plasma in the news media.

Rachul C, Rasko JEJ, Caulfield T.

PLoS One. 2017 Aug 9;12(8):e0182496. doi: 10.1371/journal.pone.0182496. eCollection 2017.

19.

ASCT2 regulates glutamine uptake and cell growth in endometrial carcinoma.

Marshall AD, van Geldermalsen M, Otte NJ, Lum T, Vellozzi M, Thoeng A, Pang A, Nagarajah R, Zhang B, Wang Q, Anderson L, Rasko JEJ, Holst J.

Oncogenesis. 2017 Jul 31;6(7):e367. doi: 10.1038/oncsis.2017.70.

20.

Challenges in defining the role of intron retention in normal biology and disease.

Vanichkina DP, Schmitz U, Wong JJ, Rasko JEJ.

Semin Cell Dev Biol. 2018 Mar;75:40-49. doi: 10.1016/j.semcdb.2017.07.030. Epub 2017 Jul 21. Review.

PMID:
28739339
21.

Marketing of unproven stem cell-based interventions: A call to action.

Sipp D, Caulfield T, Kaye J, Barfoot J, Blackburn C, Chan S, De Luca M, Kent A, McCabe C, Munsie M, Sleeboom-Faulkner M, Sugarman J, van Zimmeren E, Zarzeczny A, Rasko JEJ.

Sci Transl Med. 2017 Jul 5;9(397). pii: eaag0426. doi: 10.1126/scitranslmed.aag0426. Review.

22.

Intron retention is regulated by altered MeCP2-mediated splicing factor recruitment.

Wong JJ, Gao D, Nguyen TV, Kwok CT, van Geldermalsen M, Middleton R, Pinello N, Thoeng A, Nagarajah R, Holst J, Ritchie W, Rasko JEJ.

Nat Commun. 2017 May 8;8:15134. doi: 10.1038/ncomms15134.

23.

Computational and Experimental Identification of Tissue-Specific MicroRNA Targets.

Amirkhah R, Meshkin HN, Farazmand A, Rasko JEJ, Schmitz U.

Methods Mol Biol. 2017;1580:127-147. doi: 10.1007/978-1-4939-6866-4_11.

PMID:
28439832
24.

The antiproliferative ELF2 isoform, ELF2B, induces apoptosis in vitro and perturbs early lymphocytic development in vivo.

Guan FH, Bailey CG, Metierre C, O'Young P, Gao D, Khoo TL, Holst J, Rasko JE.

J Hematol Oncol. 2017 Mar 28;10(1):75. doi: 10.1186/s13045-017-0446-7.

25.

CTCF genetic alterations in endometrial carcinoma are pro-tumorigenic.

Marshall AD, Bailey CG, Champ K, Vellozzi M, O'Young P, Metierre C, Feng Y, Thoeng A, Richards AM, Schmitz U, Biro M, Jayasinghe R, Ding L, Anderson L, Mardis ER, Rasko JEJ.

Oncogene. 2017 Jul 20;36(29):4100-4110. doi: 10.1038/onc.2017.25. Epub 2017 Mar 20.

26.

IRFinder: assessing the impact of intron retention on mammalian gene expression.

Middleton R, Gao D, Thomas A, Singh B, Au A, Wong JJ, Bomane A, Cosson B, Eyras E, Rasko JE, Ritchie W.

Genome Biol. 2017 Mar 15;18(1):51. doi: 10.1186/s13059-017-1184-4.

27.

Show drugs work before selling them.

Sipp D, McCabe C, Rasko JE.

Nature. 2017 Mar 8;543(7644):174-175. doi: 10.1038/543174a. No abstract available.

PMID:
28277530
28.

Erratum to: Genetic alterations of m6A regulators predict poorer survival in acute myeloid leukemia.

Kwok CT, Marshall AD, Rasko JE, Wong JJ.

J Hematol Oncol. 2017 Feb 17;10(1):49. doi: 10.1186/s13045-017-0419-x. No abstract available.

29.

Genetic alterations of m6A regulators predict poorer survival in acute myeloid leukemia.

Kwok CT, Marshall AD, Rasko JE, Wong JJ.

J Hematol Oncol. 2017 Feb 2;10(1):39. doi: 10.1186/s13045-017-0410-6. Erratum in: J Hematol Oncol. 2017 Feb 17;10 (1):49.

30.

Nuclear microRNAs in normal hemopoiesis and cancer.

Rasko JE, Wong JJ.

J Hematol Oncol. 2017 Jan 5;10(1):8. doi: 10.1186/s13045-016-0375-x. Review.

31.

Global Distribution of Businesses Marketing Stem Cell-Based Interventions.

Berger I, Ahmad A, Bansal A, Kapoor T, Sipp D, Rasko JEJ.

Cell Stem Cell. 2016 Aug 4;19(2):158-162. doi: 10.1016/j.stem.2016.07.015.

32.

LAT1 is a putative therapeutic target in endometrioid endometrial carcinoma.

Marshall AD, van Geldermalsen M, Otte NJ, Anderson LA, Lum T, Vellozzi MA, Zhang BK, Thoeng A, Wang Q, Rasko JE, Holst J.

Int J Cancer. 2016 Dec 1;139(11):2529-39. doi: 10.1002/ijc.30371. Epub 2016 Aug 16.

33.

Experimental approaches to studying the nature and impact of splicing variation in zebrafish.

Keightley MC, Markmiller S, Love CG, Rasko JE, Lieschke GJ, Heath JK.

Methods Cell Biol. 2016;135:259-88. doi: 10.1016/bs.mcb.2016.02.006. Epub 2016 Mar 9.

PMID:
27443930
34.

PtdIns(3,4,5)P3-dependent Rac Exchanger 1 (PREX1) Rac-Guanine Nucleotide Exchange Factor (GEF) Activity Promotes Breast Cancer Cell Proliferation and Tumor Growth via Activation of Extracellular Signal-regulated Kinase 1/2 (ERK1/2) Signaling.

Liu HJ, Ooms LM, Srijakotre N, Man J, Vieusseux J, Waters JE, Feng Y, Bailey CG, Rasko JE, Price JT, Mitchell CA.

J Biol Chem. 2016 Aug 12;291(33):17258-70. doi: 10.1074/jbc.M116.743401. Epub 2016 Jun 29.

35.

Science, ethics and communication remain essential for the success of cell-based therapies.

Dominici M, Nichols KM, Levine AD, Rasko JE, Forte M, O'Donnell L, Koh MB, Bollard CM, Weiss DJ.

Brain Circ. 2016 Jul-Sep;2(3):146-151. doi: 10.4103/2394-8108.192525. Epub 2016 Oct 18. Review.

36.

A dynamic intron retention program in the mammalian megakaryocyte and erythrocyte lineages.

Edwards CR, Ritchie W, Wong JJ, Schmitz U, Middleton R, An X, Mohandas N, Rasko JE, Blobel GA.

Blood. 2016 Apr 28;127(17):e24-e34. doi: 10.1182/blood-2016-01-692764. Epub 2016 Mar 9.

37.

RBM3 regulates temperature sensitive miR-142-5p and miR-143 (thermomiRs), which target immune genes and control fever.

Wong JJ, Au AY, Gao D, Pinello N, Kwok CT, Thoeng A, Lau KA, Gordon JE, Schmitz U, Feng Y, Nguyen TV, Middleton R, Bailey CG, Holst J, Rasko JE, Ritchie W.

Nucleic Acids Res. 2016 Apr 7;44(6):2888-97. doi: 10.1093/nar/gkw041. Epub 2016 Jan 28.

38.

Part 2: Making the "unproven" "proven".

Weiss DJ, Rasko JE, Cuende N, Ruiz MA, Ho HN, Nordon R, Wilton S, Dominici M, Srivastava A.

Cytotherapy. 2016 Jan;18(1):120-3. doi: 10.1016/j.jcyt.2015.11.005. No abstract available.

PMID:
26719203
39.

Intron retention in mRNA: No longer nonsense: Known and putative roles of intron retention in normal and disease biology.

Wong JJ, Au AY, Ritchie W, Rasko JE.

Bioessays. 2016 Jan;38(1):41-9. doi: 10.1002/bies.201500117. Epub 2015 Nov 27. Review.

PMID:
26612485
40.

Positioning a Scientific Community on Unproven Cellular Therapies: The 2015 International Society for Cellular Therapy Perspective.

Dominici M, Nichols K, Srivastava A, Weiss DJ, Eldridge P, Cuende N, Deans RJ, Rasko JE, Levine AD, Turner L, Griffin DL, O'Donnell L, Forte M, Mason C, Wagena E, Janssen W, Nordon R, Wall D, Ho HN, Ruiz MA, Wilton S, Horwitz EM, Gunter KC; 2013–2015 ISCT Presidential Task Force on Unproven Cellular Therapy.

Cytotherapy. 2015 Dec;17(12):1663-6. doi: 10.1016/j.jcyt.2015.10.007. No abstract available.

PMID:
26589750
41.

ASCT2/SLC1A5 controls glutamine uptake and tumour growth in triple-negative basal-like breast cancer.

van Geldermalsen M, Wang Q, Nagarajah R, Marshall AD, Thoeng A, Gao D, Ritchie W, Feng Y, Bailey CG, Deng N, Harvey K, Beith JM, Selinger CI, O'Toole SA, Rasko JE, Holst J.

Oncogene. 2016 Jun 16;35(24):3201-8. doi: 10.1038/onc.2015.381. Epub 2015 Oct 12.

42.

Comparative analyses of CTCF and BORIS occupancies uncover two distinct classes of CTCF binding genomic regions.

Pugacheva EM, Rivero-Hinojosa S, Espinoza CA, Méndez-Catalá CF, Kang S, Suzuki T, Kosaka-Suzuki N, Robinson S, Nagarajan V, Ye Z, Boukaba A, Rasko JE, Strunnikov AV, Loukinov D, Ren B, Lobanenkov VV.

Genome Biol. 2015 Aug 14;16:161. doi: 10.1186/s13059-015-0736-8.

43.

Corrigendum: Genome-wide characterization of the routes to pluripotency.

Hussein SM, Puri MC, Tonge PD, Benevento M, Corso AJ, Clancy JL, Mosbergen R, Li M, Lee DS, Cloonan N, Wood DL, Munoz J, Middleton R, Korn O, Patel HR, White CA, Shin JY, Gauthier ME, Cao KA, Kim JI, Mar JC, Shakiba N, Ritchie W, Rasko JE, Grimmond SM, Zandstra PW, Wells CA, Preiss T, Seo JS, Heck AJ, Rogers IM, Nagy A.

Nature. 2015 Jul 30;523(7562):626. doi: 10.1038/nature14606. Epub 2015 Jun 17. No abstract available.

PMID:
26083747
44.

Targeting ASCT2-mediated glutamine uptake blocks prostate cancer growth and tumour development.

Wang Q, Hardie RA, Hoy AJ, van Geldermalsen M, Gao D, Fazli L, Sadowski MC, Balaban S, Schreuder M, Nagarajah R, Wong JJ, Metierre C, Pinello N, Otte NJ, Lehman ML, Gleave M, Nelson CC, Bailey CG, Ritchie W, Rasko JE, Holst J.

J Pathol. 2015 Jul;236(3):278-89. doi: 10.1002/path.4518. Epub 2015 Apr 7.

45.

Genome-wide characterization of the routes to pluripotency.

Hussein SM, Puri MC, Tonge PD, Benevento M, Corso AJ, Clancy JL, Mosbergen R, Li M, Lee DS, Cloonan N, Wood DL, Munoz J, Middleton R, Korn O, Patel HR, White CA, Shin JY, Gauthier ME, Lê Cao KA, Kim JI, Mar JC, Shakiba N, Ritchie W, Rasko JE, Grimmond SM, Zandstra PW, Wells CA, Preiss T, Seo JS, Heck AJ, Rogers IM, Nagy A.

Nature. 2014 Dec 11;516(7530):198-206. doi: 10.1038/nature14046. Erratum in: Nature. 2015 Jul 30;523(7562):626.

PMID:
25503233
46.

Small RNA changes en route to distinct cellular states of induced pluripotency.

Clancy JL, Patel HR, Hussein SM, Tonge PD, Cloonan N, Corso AJ, Li M, Lee DS, Shin JY, Wong JJ, Bailey CG, Benevento M, Munoz J, Chuah A, Wood D, Rasko JE, Heck AJ, Grimmond SM, Rogers IM, Seo JS, Wells CA, Puri MC, Nagy A, Preiss T.

Nat Commun. 2014 Dec 10;5:5522. doi: 10.1038/ncomms6522.

PMID:
25494340
47.

Epigenetic modifications of splicing factor genes in myelodysplastic syndromes and acute myeloid leukemia.

Wong JJ, Lau KA, Pinello N, Rasko JE.

Cancer Sci. 2014 Nov;105(11):1457-63. doi: 10.1111/cas.12532. Epub 2014 Oct 18.

48.

Identification of nuclear-enriched miRNAs during mouse granulopoiesis.

Wong JJ, Ritchie W, Gao D, Lau KA, Gonzalez M, Choudhary A, Taft RJ, Rasko JE, Holst J.

J Hematol Oncol. 2014 May 15;7:42. doi: 10.1186/1756-8722-7-42.

49.

Monoterpene glycoside ESK246 from Pittosporum targets LAT3 amino acid transport and prostate cancer cell growth.

Wang Q, Grkovic T, Font J, Bonham S, Pouwer RH, Bailey CG, Moran AM, Ryan RM, Rasko JE, Jormakka M, Quinn RJ, Holst J.

ACS Chem Biol. 2014 Jun 20;9(6):1369-76. doi: 10.1021/cb500120x. Epub 2014 May 5.

50.

CTCF and BORIS in genome regulation and cancer.

Marshall AD, Bailey CG, Rasko JE.

Curr Opin Genet Dev. 2014 Feb;24:8-15. doi: 10.1016/j.gde.2013.10.011. Epub 2013 Dec 14. Review.

PMID:
24657531

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