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Items: 1 to 50 of 149

1.

Improving Our Understanding of Salmonella enterica Serovar Paratyphi B through the Engineering and Testing of a Live Attenuated Vaccine Strain.

Higginson EE, Ramachandran G, Hazen TH, Kania DA, Rasko DA, Pasetti MF, Levine MM, Tennant SM.

mSphere. 2018 Nov 28;3(6). pii: e00474-18. doi: 10.1128/mSphere.00474-18.

2.

Coli Surface Antigen 26 Acts as an Adherence Determinant of Enterotoxigenic Escherichia coli and Is Cross-Recognized by Anti-CS20 Antibodies.

Cádiz L, Torres A, Valdés R, Vera G, Gutiérrez D, Levine MM, Montero DA, O'Ryan M, Rasko DA, Stine OC, Vidal R, Del Canto F.

Front Microbiol. 2018 Oct 16;9:2463. doi: 10.3389/fmicb.2018.02463. eCollection 2018.

3.

Temporal Variability of Escherichia coli Diversity in the Gastrointestinal Tracts of Tanzanian Children with and without Exposure to Antibiotics.

Richter TKS, Hazen TH, Lam D, Coles CL, Seidman JC, You Y, Silbergeld EK, Fraser CM, Rasko DA.

mSphere. 2018 Nov 7;3(6). pii: e00558-18. doi: 10.1128/mSphere.00558-18.

4.

Targeted enrichment outperforms other enrichment techniques and enables more multi-species RNA-Seq analyses.

Chung M, Teigen L, Liu H, Libro S, Shetty A, Kumar N, Zhao X, Bromley RE, Tallon LJ, Sadzewicz L, Fraser CM, Rasko DA, Filler SG, Foster JM, Michalski ML, Bruno VM, Dunning Hotopp JC.

Sci Rep. 2018 Sep 6;8(1):13377. doi: 10.1038/s41598-018-31420-7.

5.

A Novel Shigella Proteome Microarray Discriminates Targets of Human Antibody Reactivity following Oral Vaccination and Experimental Challenge.

Ndungo E, Randall A, Hazen TH, Kania DA, Trappl-Kimmons K, Liang X, Barry EM, Kotloff KL, Chakraborty S, Mani S, Rasko DA, Pasetti MF.

mSphere. 2018 Aug 1;3(4). pii: e00260-18. doi: 10.1128/mSphere.00260-18.

6.

Responses of the Human Gut Escherichia coli Population to Pathogen and Antibiotic Disturbances.

Richter TKS, Michalski JM, Zanetti L, Tennant SM, Chen WH, Rasko DA.

mSystems. 2018 Jul 24;3(4). pii: e00047-18. doi: 10.1128/mSystems.00047-18. eCollection 2018 Jul-Aug.

7.

Diversity among blaKPC-containing plasmids in Escherichia coli and other bacterial species isolated from the same patients.

Hazen TH, Mettus R, McElheny CL, Bowler SL, Nagaraj S, Doi Y, Rasko DA.

Sci Rep. 2018 Jul 6;8(1):10291. doi: 10.1038/s41598-018-28085-7.

8.

Human Experimental Challenge With Enterotoxigenic Escherichia coli Elicits Immune Responses to Canonical and Novel Antigens Relevant to Vaccine Development.

Chakraborty S, Randall A, Vickers TJ, Molina D, Harro CD, DeNearing B, Brubaker J, Sack DA, Bourgeois AL, Felgner PL, Liang X, Mani S, Wenzel H, Townsend RR, Gilmore PE, Darsley MJ, Rasko DA, Fleckenstein JM.

J Infect Dis. 2018 Sep 22;218(9):1436-1446. doi: 10.1093/infdis/jiy312.

PMID:
29800314
9.

Phosphotyrosine-Mediated Regulation of Enterohemorrhagic Escherichia coli Virulence.

Robertson CD, Hazen TH, Kaper JB, Rasko DA, Hansen AM.

MBio. 2018 Feb 27;9(1). pii: e00097-18. doi: 10.1128/mBio.00097-18.

10.

Draft Genome Sequences of blaKPC-Containing Enterobacter aerogenes, Citrobacter freundii, and Citrobacter koseri Strains.

Hazen TH, Mettus RT, McElheny CL, Bowler SL, Doi Y, Rasko DA.

Genome Announc. 2018 Feb 22;6(8). pii: e00035-18. doi: 10.1128/genomeA.00035-18.

11.

Aligner optimization increases accuracy and decreases compute times in multi-species sequence data.

Robinson KM, Hawkins AS, Santana-Cruz I, Adkins RS, Shetty AC, Nagaraj S, Sadzewicz L, Tallon LJ, Rasko DA, Fraser CM, Mahurkar A, Silva JC, Dunning Hotopp JC.

Microb Genom. 2017 Jul 8;3(9):e000122. doi: 10.1099/mgen.0.000122. eCollection 2017 Sep.

12.

Structural modification of LPS in colistin-resistant, KPC-producing Klebsiella pneumoniae.

Leung LM, Cooper VS, Rasko DA, Guo Q, Pacey MP, McElheny CL, Mettus RT, Yoon SH, Goodlett DR, Ernst RK, Doi Y.

J Antimicrob Chemother. 2017 Nov 1;72(11):3035-3042. doi: 10.1093/jac/dkx234.

13.

The AraC Negative Regulator family modulates the activity of histone-like proteins in pathogenic bacteria.

Santiago AE, Yan MB, Hazen TH, Sauder B, Meza-Segura M, Rasko DA, Kendall MM, Ruiz-Perez F, Nataro JP.

PLoS Pathog. 2017 Aug 14;13(8):e1006545. doi: 10.1371/journal.ppat.1006545. eCollection 2017 Aug.

14.

Transcriptional Variation of Diverse Enteropathogenic Escherichia coli Isolates under Virulence-Inducing Conditions.

Hazen TH, Daugherty SC, Shetty AC, Nataro JP, Rasko DA.

mSystems. 2017 Jul 25;2(4). pii: e00024-17. doi: 10.1128/mSystems.00024-17. eCollection 2017 Jul-Aug.

15.

Locus of Adhesion and Autoaggregation (LAA), a pathogenicity island present in emerging Shiga Toxin-producing Escherichia coli strains.

Montero DA, Velasco J, Del Canto F, Puente JL, Padola NL, Rasko DA, Farfán M, Salazar JC, Vidal R.

Sci Rep. 2017 Aug 1;7(1):7011. doi: 10.1038/s41598-017-06999-y.

16.

Characterization of a Large Antibiotic Resistance Plasmid Found in Enteropathogenic Escherichia coli Strain B171 and Its Relatedness to Plasmids of Diverse E. coli and Shigella Strains.

Hazen TH, Michalski J, Nagaraj S, Okeke IN, Rasko DA.

Antimicrob Agents Chemother. 2017 Aug 24;61(9). pii: e00995-17. doi: 10.1128/AAC.00995-17. Print 2017 Sep.

17.

Comparative genomics and transcriptomics of Escherichia coli isolates carrying virulence factors of both enteropathogenic and enterotoxigenic E. coli.

Hazen TH, Michalski J, Luo Q, Shetty AC, Daugherty SC, Fleckenstein JM, Rasko DA.

Sci Rep. 2017 Jun 14;7(1):3513. doi: 10.1038/s41598-017-03489-z.

18.

Insights into enterotoxigenic Escherichia coli diversity in Bangladesh utilizing genomic epidemiology.

Sahl JW, Sistrunk JR, Baby NI, Begum Y, Luo Q, Sheikh A, Qadri F, Fleckenstein JM, Rasko DA.

Sci Rep. 2017 Jun 13;7(1):3402. doi: 10.1038/s41598-017-03631-x.

19.

Changes in microbiome during and after travellers' diarrhea: what we know and what we do not.

Rasko DA.

J Travel Med. 2017 Apr 1;24(suppl_1):S52-S56. doi: 10.1093/jtm/tax017. Review.

20.

Analysis of Shigella flexneri Resistance, Biofilm Formation, and Transcriptional Profile in Response to Bile Salts.

Nickerson KP, Chanin RB, Sistrunk JR, Rasko DA, Fink PJ, Barry EM, Nataro JP, Faherty CS.

Infect Immun. 2017 May 23;85(6). pii: e01067-16. doi: 10.1128/IAI.01067-16. Print 2017 Jun.

21.

Chaperone-Usher Pili Loci of Colonization Factor-Negative Human Enterotoxigenic Escherichia coli.

Del Canto F, O'Ryan M, Pardo M, Torres A, Gutiérrez D, Cádiz L, Valdés R, Mansilla A, Martínez R, Hernández D, Caro B, Levine MM, Rasko DA, Hill CM, Pop M, Stine OC, Vidal R.

Front Cell Infect Microbiol. 2017 Jan 6;6:200. doi: 10.3389/fcimb.2016.00200. eCollection 2016.

22.

The synthesis of OspD3 (ShET2) in Shigella flexneri is independent of OspC1.

Faherty CS, Wu T, Morris CR, Grassel CL, Rasko DA, Harper JM, Shea-Donohue T, Fasano A, Barry EM.

Gut Microbes. 2016 Nov;7(6):486-502. Epub 2016 Sep 22.

23.

Draft Genome Sequence of Biocontrol Agent Bacillus cereus UW85.

Lozano GL, Holt J, Ravel J, Rasko DA, Thomas MG, Handelsman J.

Genome Announc. 2016 Sep 1;4(5). pii: e00910-16. doi: 10.1128/genomeA.00910-16.

24.

Genomic diversity of EPEC associated with clinical presentations of differing severity.

Hazen TH, Donnenberg MS, Panchalingam S, Antonio M, Hossain A, Mandomando I, Ochieng JB, Ramamurthy T, Tamboura B, Qureshi S, Quadri F, Zaidi A, Kotloff KL, Levine MM, Barry EM, Kaper JB, Rasko DA, Nataro JP.

Nat Microbiol. 2016 Jan 18;1:15014. doi: 10.1038/nmicrobiol.2015.14.

25.

Survival of the Fittest: How Bacterial Pathogens Utilize Bile To Enhance Infection.

Sistrunk JR, Nickerson KP, Chanin RB, Rasko DA, Faherty CS.

Clin Microbiol Rev. 2016 Oct;29(4):819-36. doi: 10.1128/CMR.00031-16. Review.

26.

Use of Comparative Genomics To Characterize the Diversity of Acinetobacter baumannii Surveillance Isolates in a Health Care Institution.

Wallace L, Daugherty SC, Nagaraj S, Johnson JK, Harris AD, Rasko DA.

Antimicrob Agents Chemother. 2016 Sep 23;60(10):5933-41. doi: 10.1128/AAC.00477-16. Print 2016 Oct.

27.

An integrated genomic and transcriptomic survey of mucormycosis-causing fungi.

Chibucos MC, Soliman S, Gebremariam T, Lee H, Daugherty S, Orvis J, Shetty AC, Crabtree J, Hazen TH, Etienne KA, Kumari P, O'Connor TD, Rasko DA, Filler SG, Fraser CM, Lockhart SR, Skory CD, Ibrahim AS, Bruno VM.

Nat Commun. 2016 Jul 22;7:12218. doi: 10.1038/ncomms12218.

28.

Investigating the Relatedness of Enteroinvasive Escherichia coli to Other E. coli and Shigella Isolates by Using Comparative Genomics.

Hazen TH, Leonard SR, Lampel KA, Lacher DW, Maurelli AT, Rasko DA.

Infect Immun. 2016 Jul 21;84(8):2362-2371. doi: 10.1128/IAI.00350-16. Print 2016 Aug.

29.

Hybrid Shiga Toxin-Producing and Enterotoxigenic Escherichia sp. Cryptic Lineage 1 Strain 7v Harbors a Hybrid Plasmid.

Leonard SR, Mammel MK, Rasko DA, Lacher DW.

Appl Environ Microbiol. 2016 Jun 30;82(14):4309-4319. doi: 10.1128/AEM.01129-16. Print 2016 Jul 15.

30.

Overcoming Enterotoxigenic Escherichia coli Pathogen Diversity: Translational Molecular Approaches to Inform Vaccine Design.

Fleckenstein JM, Rasko DA.

Methods Mol Biol. 2016;1403:363-83. doi: 10.1007/978-1-4939-3387-7_19.

31.

Genome diversity of Shigella boydii.

Kania DA, Hazen TH, Hossain A, Nataro JP, Rasko DA.

Pathog Dis. 2016 Jun;74(4):ftw027. doi: 10.1093/femspd/ftw027. Epub 2016 Apr 6.

32.

Diarrhea, bacteremia and multiorgan dysfunction due to an extraintestinal pathogenic Escherichia coli strain with enteropathogenic E. coli genes.

Kessler R, Nisa S, Hazen TH, Horneman A, Amoroso A, Rasko DA, Donnenberg MS.

Pathog Dis. 2015 Nov;73(8):ftv076. doi: 10.1093/femspd/ftv076. Epub 2015 Sep 26.

33.

Comparative Genomics Provides Insight into the Diversity of the Attaching and Effacing Escherichia coli Virulence Plasmids.

Hazen TH, Kaper JB, Nataro JP, Rasko DA.

Infect Immun. 2015 Oct;83(10):4103-17. doi: 10.1128/IAI.00769-15. Epub 2015 Aug 3.

34.

Phylogenetically typing bacterial strains from partial SNP genotypes observed from direct sequencing of clinical specimen metagenomic data.

Sahl JW, Schupp JM, Rasko DA, Colman RE, Foster JT, Keim P.

Genome Med. 2015 Jun 9;7(1):52. doi: 10.1186/s13073-015-0176-9. eCollection 2015.

35.

RNA-Seq analysis of isolate- and growth phase-specific differences in the global transcriptomes of enteropathogenic Escherichia coli prototype isolates.

Hazen TH, Daugherty SC, Shetty A, Mahurkar AA, White O, Kaper JB, Rasko DA.

Front Microbiol. 2015 Jun 12;6:569. doi: 10.3389/fmicb.2015.00569. eCollection 2015.

36.

EHEC Genomics: Past, Present, and Future.

Sadiq SM, Hazen TH, Rasko DA, Eppinger M.

Microbiol Spectr. 2014 Aug;2(4):EHEC-0020-2013. doi: 10.1128/microbiolspec.EHEC-0020-2013. Review.

PMID:
26104203
37.

Examination of the Enterotoxigenic Escherichia coli Population Structure during Human Infection.

Sahl JW, Sistrunk JR, Fraser CM, Hine E, Baby N, Begum Y, Luo Q, Sheikh A, Qadri F, Fleckenstein JM, Rasko DA.

MBio. 2015 Jun 9;6(3):e00501. doi: 10.1128/mBio.00501-15.

38.

Bacterial Factors Associated with Lethal Outcome of Enteropathogenic Escherichia coli Infection: Genomic Case-Control Studies.

Donnenberg MS, Hazen TH, Farag TH, Panchalingam S, Antonio M, Hossain A, Mandomando I, Ochieng JB, Ramamurthy T, Tamboura B, Zaidi A, Levine MM, Kotloff K, Rasko DA, Nataro JP.

PLoS Negl Trop Dis. 2015 May 15;9(5):e0003791. doi: 10.1371/journal.pntd.0003791. eCollection 2015 May.

39.

Characterization of the pathogenome and phylogenomic classification of enteropathogenic Escherichia coli of the O157:non-H7 serotypes.

Sanjar F, Rusconi B, Hazen TH, Koenig SS, Mammel MK, Feng PC, Rasko DA, Eppinger M.

Pathog Dis. 2015 Jul;73(5). pii: ftv033. doi: 10.1093/femspd/ftv033. Epub 2015 May 10.

40.

Insights into the environmental reservoir of pathogenic Vibrio parahaemolyticus using comparative genomics.

Hazen TH, Lafon PC, Garrett NM, Lowe TM, Silberger DJ, Rowe LA, Frace M, Parsons MB, Bopp CA, Rasko DA, Sobecky PA.

Front Microbiol. 2015 Mar 24;6:204. doi: 10.3389/fmicb.2015.00204. eCollection 2015.

41.

Conservation and immunogenicity of novel antigens in diverse isolates of enterotoxigenic Escherichia coli.

Luo Q, Qadri F, Kansal R, Rasko DA, Sheikh A, Fleckenstein JM.

PLoS Negl Trop Dis. 2015 Jan 28;9(1):e0003446. doi: 10.1371/journal.pntd.0003446. eCollection 2015 Jan. Erratum in: PLoS Negl Trop Dis. 2015 Jun;9(6):e0003858.

42.

Blocking yersiniabactin import attenuates extraintestinal pathogenic Escherichia coli in cystitis and pyelonephritis and represents a novel target to prevent urinary tract infection.

Brumbaugh AR, Smith SN, Subashchandrabose S, Himpsl SD, Hazen TH, Rasko DA, Mobley HL.

Infect Immun. 2015 Apr;83(4):1443-50. doi: 10.1128/IAI.02904-14. Epub 2015 Jan 26.

43.

Defining the phylogenomics of Shigella species: a pathway to diagnostics.

Sahl JW, Morris CR, Emberger J, Fraser CM, Ochieng JB, Juma J, Fields B, Breiman RF, Gilmour M, Nataro JP, Rasko DA.

J Clin Microbiol. 2015 Mar;53(3):951-60. doi: 10.1128/JCM.03527-14. Epub 2015 Jan 14.

44.

Host-specific induction of Escherichia coli fitness genes during human urinary tract infection.

Subashchandrabose S, Hazen TH, Brumbaugh AR, Himpsl SD, Smith SN, Ernst RD, Rasko DA, Mobley HL.

Proc Natl Acad Sci U S A. 2014 Dec 23;111(51):18327-32. doi: 10.1073/pnas.1415959112. Epub 2014 Dec 8.

45.

QseC inhibitors as an antivirulence approach for Gram-negative pathogens.

Curtis MM, Russell R, Moreira CG, Adebesin AM, Wang C, Williams NS, Taussig R, Stewart D, Zimmern P, Lu B, Prasad RN, Zhu C, Rasko DA, Huntley JF, Falck JR, Sperandio V.

MBio. 2014 Nov 11;5(6):e02165. doi: 10.1128/mBio.02165-14.

46.

Identification of enterotoxigenic Escherichia coli (ETEC) clades with long-term global distribution.

von Mentzer A, Connor TR, Wieler LH, Semmler T, Iguchi A, Thomson NR, Rasko DA, Joffre E, Corander J, Pickard D, Wiklund G, Svennerholm AM, Sjöling Å, Dougan G.

Nat Genet. 2014 Dec;46(12):1321-6. doi: 10.1038/ng.3145. Epub 2014 Nov 10.

PMID:
25383970
47.

Circleator: flexible circular visualization of genome-associated data with BioPerl and SVG.

Crabtree J, Agrawal S, Mahurkar A, Myers GS, Rasko DA, White O.

Bioinformatics. 2014 Nov 1;30(21):3125-7. doi: 10.1093/bioinformatics/btu505. Epub 2014 Jul 29.

48.

Whole-genome assembly of Klebsiella pneumoniae coproducing NDM-1 and OXA-232 carbapenemases using single-molecule, real-time sequencing.

Doi Y, Hazen TH, Boitano M, Tsai YC, Clark TA, Korlach J, Rasko DA.

Antimicrob Agents Chemother. 2014 Oct;58(10):5947-53. doi: 10.1128/AAC.03180-14. Epub 2014 Jul 28.

49.

Exploiting the explosion of information associated with whole genome sequencing to tackle Shiga toxin-producing Escherichia coli (STEC) in global food production systems.

Franz E, Delaquis P, Morabito S, Beutin L, Gobius K, Rasko DA, Bono J, French N, Osek J, Lindstedt BA, Muniesa M, Manning S, LeJeune J, Callaway T, Beatson S, Eppinger M, Dallman T, Forbes KJ, Aarts H, Pearl DL, Gannon VP, Laing CR, Strachan NJ.

Int J Food Microbiol. 2014 Sep 18;187:57-72. doi: 10.1016/j.ijfoodmicro.2014.07.002. Epub 2014 Jul 11. Review. Erratum in: Int J Food Microbiol. 2015 Jan 16;193:159.

PMID:
25051454
50.

Draft Genome Sequences of Nine Enteropathogenic Escherichia coli Strains from Kenya.

Hazen TH, Humphrys MS, Ochieng JB, Parsons M, Bopp CA, O'Reilly CE, Mintz E, Rasko DA.

Genome Announc. 2014 Jun 12;2(3). pii: e00582-14. doi: 10.1128/genomeA.00582-14.

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