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Items: 1 to 50 of 106

1.

Regulation of Differentiation of HC11 Mouse Breast Epithelial Cells by the Signal Transducer and Activator of Transcription-3.

Niit M, Geletu M, Taha Z, Arulanandam R, Cass J, Hoskin V, Elliott B, Gunning P, Raptis L.

Anticancer Res. 2019 Jun;39(6):2749-2756. doi: 10.21873/anticanres.13401.

PMID:
31177110
2.

Effect of caveolin-1 on Stat3-ptyr705 levels in breast and lung carcinoma cells.

Geletu M, Taha Z, Arulanandam R, Mohan R, Assi HH, Castro MG, Nabi IR, Gunning PT, Raptis L.

Biochem Cell Biol. 2019 Oct;97(5):638-646. doi: 10.1139/bcb-2018-0367. Epub 2019 Apr 15.

3.

PI3k and Stat3: Oncogenes that are Required for Gap Junctional, Intercellular Communication.

Geletu M, Taha Z, Gunning PT, Raptis L.

Cancers (Basel). 2019 Feb 1;11(2). pii: E167. doi: 10.3390/cancers11020167. Review.

4.

Reciprocal regulation of the Cadherin-11/Stat3 axis by caveolin-1 in mouse fibroblasts and lung carcinoma cells.

Geletu M, Mohan R, Arulanandam R, Berger-Becvar A, Nabi IR, Gunning PT, Raptis L.

Biochim Biophys Acta Mol Cell Res. 2018 May;1865(5):794-802. doi: 10.1016/j.bbamcr.2018.02.004. Epub 2018 Feb 16.

5.

FRK inhibits breast cancer cell migration and invasion by suppressing epithelial-mesenchymal transition.

Ogunbolude Y, Dai C, Bagu ET, Goel RK, Miah S, MacAusland-Berg J, Ng CY, Chibbar R, Napper S, Raptis L, Vizeacoumar F, Vizeacoumar F, Bonham K, Lukong KE.

Oncotarget. 2017 Dec 6;8(68):113034-113065. doi: 10.18632/oncotarget.22958. eCollection 2017 Dec 22.

6.

Regulation of HC11 mouse breast epithelial cell differentiation by the E-cadherin/Rac axis.

Niit M, Arulanandam R, Cass J, Geletu M, Hoskin V, Côté G, Gunning P, Elliott B, Raptis L.

Exp Cell Res. 2017 Dec 1;361(1):112-125. doi: 10.1016/j.yexcr.2017.10.008. Epub 2017 Oct 13.

PMID:
29031557
7.

Dataset of STAT5A status in breast cancer.

Mukhopadhyay UK, Cass J, Raptis L, Craig AW, Bourdeau V, Varma S, Gupta SS, Elliott BE, Ferbeyre G.

Data Brief. 2016 Mar 4;7:490-2. doi: 10.1016/j.dib.2016.02.073. eCollection 2016 Jun.

8.

STAT5A is regulated by DNA damage via the tumor suppressor p53.

Mukhopadhyay UK, Cass J, Raptis L, Craig AW, Bourdeau V, Varma S, SenGupta S, Elliott BE, Ferbeyre G.

Cytokine. 2016 Jun;82:70-9. doi: 10.1016/j.cyto.2016.01.013. Epub 2016 Feb 11.

PMID:
26876578
9.

Cell-cell and cell-matrix adhesion in survival and metastasis: Stat3 versus Akt.

Niit M, Hoskin V, Carefoot E, Geletu M, Arulanandam R, Elliott B, Raptis L.

Biomol Concepts. 2015 Dec;6(5-6):383-99. doi: 10.1515/bmc-2015-0022. Review.

PMID:
26565555
10.

VEGF-Mediated Induction of PRD1-BF1/Blimp1 Expression Sensitizes Tumor Vasculature to Oncolytic Virus Infection.

Arulanandam R, Batenchuk C, Angarita FA, Ottolino-Perry K, Cousineau S, Mottashed A, Burgess E, Falls TJ, De Silva N, Tsang J, Howe GA, Bourgeois-Daigneault MC, Conrad DP, Daneshmand M, Breitbach CJ, Kirn DH, Raptis L, Sad S, Atkins H, Huh MS, Diallo JS, Lichty BD, Ilkow CS, Le Boeuf F, Addison CL, McCart JA, Bell JC.

Cancer Cell. 2015 Aug 10;28(2):210-24. doi: 10.1016/j.ccell.2015.06.009. Epub 2015 Jul 23.

11.

Differential effects of polyoma virus middle tumor antigen mutants upon gap junctional, intercellular communication.

Geletu M, Guy S, Greer S, Raptis L.

Exp Cell Res. 2015 Aug 15;336(2):223-31. doi: 10.1016/j.yexcr.2015.07.013. Epub 2015 Jul 14.

PMID:
26187405
12.

A functional assay for gap junctional examination; electroporation of adherent cells on indium-tin oxide.

Geletu M, Guy S, Firth K, Raptis L.

J Vis Exp. 2014 Oct 18;(92):e51710. doi: 10.3791/51710.

13.

Preclinical characterization of signal transducer and activator of transcription 3 small molecule inhibitors for primary and metastatic brain cancer therapy.

Assi HH, Paran C, VanderVeen N, Savakus J, Doherty R, Petruzzella E, Hoeschele JD, Appelman H, Raptis L, Mikkelsen T, Lowenstein PR, Castro MG.

J Pharmacol Exp Ther. 2014 Jun;349(3):458-69. doi: 10.1124/jpet.114.214619. Epub 2014 Apr 2.

14.

Stat3 and gap junctions in normal and lung cancer cells.

Guy S, Geletu M, Arulanandam R, Raptis L.

Cancers (Basel). 2014 Mar 25;6(2):646-62. doi: 10.3390/cancers6020646.

15.

Engaged for survival: From cadherin ligation to STAT3 activation.

Geletu M, Guy S, Arulanandam R, Feracci H, Raptis L.

JAKSTAT. 2013 Oct 1;2(4):e27363. doi: 10.4161/jkst.27363. Epub 2013 Dec 6. Review.

16.

Effects of SRC and STAT3 upon gap junctional, intercellular communication in lung cancer lines.

Geletu M, Guy S, Raptis L.

Anticancer Res. 2013 Oct;33(10):4401-10.

PMID:
24123009
17.

Classical cadherins control survival through the gp130/Stat3 axis.

Geletu M, Arulanandam R, Chevalier S, Saez B, Larue L, Feracci H, Raptis L.

Biochim Biophys Acta. 2013 Aug;1833(8):1947-59. doi: 10.1016/j.bbamcr.2013.03.014. Epub 2013 Mar 27.

18.

Stat3 is a positive regulator of gap junctional intercellular communication in cultured, human lung carcinoma cells.

Geletu M, Arulanandam R, Greer S, Trotman-Grant A, Tomai E, Raptis L.

BMC Cancer. 2012 Dec 18;12:605. doi: 10.1186/1471-2407-12-605.

19.

Mind the gap; regulation of gap junctional, intercellular communication by the SRC oncogene product and its effectors.

Geletu M, Trotman-Grant A, Raptis L.

Anticancer Res. 2012 Oct;32(10):4245-50. Review.

PMID:
23060544
20.

Automated Quantitative Analysis of p53, Cyclin D1, Ki67 and pERK Expression in Breast Carcinoma Does Not Differ from Expert Pathologist Scoring and Correlates with Clinico-Pathological Characteristics.

Cass JD, Varma S, Day AG, Sangrar W, Rajput AB, Raptis LH, Squire J, Madarnas Y, Sengupta SK, Elliott BE.

Cancers (Basel). 2012 Jul 18;4(3):725-42. doi: 10.3390/cancers4030725.

21.

The R(h)oads to Stat3: Stat3 activation by the Rho GTPases.

Raptis L, Arulanandam R, Geletu M, Turkson J.

Exp Cell Res. 2011 Aug 1;317(13):1787-95. doi: 10.1016/j.yexcr.2011.05.008. Epub 2011 May 18. Review.

22.

Characterization of the oncogenic activity of the novel TRIM59 gene in mouse cancer models.

Valiyeva F, Jiang F, Elmaadawi A, Moussa M, Yee SP, Raptis L, Izawa JI, Yang BB, Greenberg NM, Wang F, Xuan JW.

Mol Cancer Ther. 2011 Jul;10(7):1229-40. doi: 10.1158/1535-7163.MCT-11-0077. Epub 2011 May 18.

23.

TAZ is a novel oncogene in non-small cell lung cancer.

Zhou Z, Hao Y, Liu N, Raptis L, Tsao MS, Yang X.

Oncogene. 2011 May 5;30(18):2181-6. doi: 10.1038/onc.2010.606. Epub 2011 Jan 24.

PMID:
21258416
24.

eIF2{alpha} Kinase PKR modulates the hypoxic response by Stat3-dependent transcriptional suppression of HIF-1{alpha}.

Papadakis AI, Paraskeva E, Peidis P, Muaddi H, Li S, Raptis L, Pantopoulos K, Simos G, Koromilas AE.

Cancer Res. 2010 Oct 15;70(20):7820-9. doi: 10.1158/0008-5472.CAN-10-0215. Epub 2010 Oct 5.

25.

Doubles game: Src-Stat3 versus p53-PTEN in cellular migration and invasion.

Mukhopadhyay UK, Mooney P, Jia L, Eves R, Raptis L, Mak AS.

Mol Cell Biol. 2010 Nov;30(21):4980-95. doi: 10.1128/MCB.00004-10. Epub 2010 Aug 23.

26.

Housekeeping genes; expression levels may change with density of cultured cells.

Greer S, Honeywell R, Geletu M, Arulanandam R, Raptis L.

J Immunol Methods. 2010 Apr 15;355(1-2):76-9. doi: 10.1016/j.jim.2010.02.006. Epub 2010 Feb 19.

PMID:
20171969
27.

The simian virus 40 large tumor antigen activates cSrc and requires cSrc for full neoplastic transformation.

Arulanandam R, Geletu M, Raptis L.

Anticancer Res. 2010 Jan;30(1):47-53.

PMID:
20150616
28.

Beyond structure, to survival: activation of Stat3 by cadherin engagement.

Raptis L, Arulanandam R, Vultur A, Geletu M, Chevalier S, Feracci H.

Biochem Cell Biol. 2009 Dec;87(6):835-43. doi: 10.1139/o09-061. Review.

PMID:
19935869
29.

Activated Rac1 requires gp130 for Stat3 activation, cell proliferation and migration.

Arulanandam R, Geletu M, Feracci H, Raptis L.

Exp Cell Res. 2010 Mar 10;316(5):875-86. doi: 10.1016/j.yexcr.2009.10.017. Epub 2009 Oct 21.

PMID:
19852956
30.

Cadherin-cadherin engagement promotes cell survival via Rac1/Cdc42 and signal transducer and activator of transcription-3.

Arulanandam R, Vultur A, Cao J, Carefoot E, Elliott BE, Truesdell PF, Larue L, Feracci H, Raptis L.

Mol Cancer Res. 2009 Aug;7(8):1310-27. doi: 10.1158/1541-7786.MCR-08-0469. Epub 2009 Aug 11.

31.

Stat3 activity is required for gap junctional permeability in normal rat liver epithelial cells.

Geletu M, Chaize C, Arulanandam R, Vultur A, Kowolik C, Anagnostopoulou A, Jove R, Raptis L.

DNA Cell Biol. 2009 Jul;28(7):319-27. doi: 10.1089/dna.2008.0833.

PMID:
19456249
32.

Electroporation of adherent cells in situ for the study of signal transduction and gap junctional communication.

Raptis L, Vultur A, Brownell HL, Tomai E, Anagnostopoulou A, Arulanandam R, Cao J, Firth KL.

Methods Mol Biol. 2008;423:173-89. doi: 10.1007/978-1-59745-194-9_12.

PMID:
18370198
33.

Electrode assemblies used for electroporation of cultured cells.

Raptis L, Firth KL.

Methods Mol Biol. 2008;423:61-76. doi: 10.1007/978-1-59745-194-9_4.

PMID:
18370190
34.

Synthesis, characterization and Stat3 inhibitory properties of the prototypical platinum(IV) anticancer drug, [PtCl3(NO2)(NH3)2] (CPA-7).

Littlefield SL, Baird MC, Anagnostopoulou A, Raptis L.

Inorg Chem. 2008 Apr 7;47(7):2798-804. doi: 10.1021/ic702057q. Epub 2008 Feb 13.

PMID:
18269242
35.

Examination of gap junctional, intercellular communication by in situ electroporation on two co-planar indium-tin oxide electrodes.

Anagnostopoulou A, Cao J, Vultur A, Firth K, Raptis L.

Mol Oncol. 2007 Sep;1(2):226-31. doi: 10.1016/j.molonc.2007.06.002. Epub 2007 Jun 20.

36.

Primary malignant peritoneal mesothelioma associated with Metsovo lung.

Raptis L, Efpraxia M, Akritidis N.

JBR-BTR. 2007 May-Jun;90(3):204-5. No abstract available.

PMID:
17696098
37.

Differential effects of c-Ras upon transformation, adipocytic differentiation, and apoptosis mediated by the simian virus 40 large tumor antigen.

Cao J, Arulanandam R, Vultur A, Anagnostopoulou A, Raptis L.

Biochem Cell Biol. 2007 Feb;85(1):32-48. Erratum in: Biochem Cell Biol. 2007 Jun;85(3):395. Anagnostopoulu, Aikaterini [corrected to Anagnostopoulou, Aikaterini]. Biochem Cell Biol. 2008 Apr;86(2):214-5.

PMID:
17464343
38.

Horton's three sisters: familial clustering of temporal arteritis.

Raptis L, Pappas G, Akritidis N.

Clin Rheumatol. 2007 Nov;26(11):1997-8. Epub 2007 Mar 27.

PMID:
17387531
39.

Diltiazem-induced eosinophilic pleural effusion.

Raptis L, Pappas G, Katsanou A, Koutsouka F, Petrakis D, Akritidis N.

Pharmacotherapy. 2007 Apr;27(4):600-2.

PMID:
17381387
40.

Adenovirus E1A requires c-Ras for full neoplastic transformation or suppression of differentiation of murine preadipocytes.

Cao J, Arulanandam R, Vultur A, Anagnostopoulou A, Raptis L.

Mol Carcinog. 2007 Apr;46(4):284-302.

PMID:
17295229
41.

It's all in the face: amiodarone-induced myxedema and skin pigmentation.

Raptis L, Papathanasiou H, Pappas G, Akritidis N.

Eur J Dermatol. 2006 Sep-Oct;16(5):590-1. No abstract available.

PMID:
17101492
42.

Use of ceftriaxone in patients with severe leptospirosis.

Raptis L, Pappas G, Akritidis N.

Int J Antimicrob Agents. 2006 Sep;28(3):259-61. Epub 2006 Aug 7.

PMID:
16891097
43.

A cutaneous cyst caused by brucellosis with a negative serological test.

Raptis L, Pappas G, Akritidis N.

Int J Infect Dis. 2007 Jan;11(1):82-3. Epub 2006 Feb 15. No abstract available.

44.

CT evaluation of renal artery embolism with ectopic artery.

Raptis L, Androulaki M, Passas G, Akritidis N.

Eur J Intern Med. 2006 Jan;17(1):61-2.

PMID:
16378891
45.

Differential effects of Stat3 inhibition in sparse vs confluent normal and breast cancer cells.

Anagnostopoulou A, Vultur A, Arulanandam R, Cao J, Turkson J, Jove R, Kim JS, Glenn M, Hamilton AD, Raptis L.

Cancer Lett. 2006 Oct 8;242(1):120-32. Epub 2005 Dec 27.

PMID:
16377083
46.

Stat3 is required for full neoplastic transformation by the Simian Virus 40 large tumor antigen.

Vultur A, Arulanandam R, Turkson J, Niu G, Jove R, Raptis L.

Mol Biol Cell. 2005 Aug;16(8):3832-46. Epub 2005 May 25.

47.

Adenovirus-5 E1A suppresses differentiation of 3T3 L1 preadipocytes at lower levels than required for induction of apoptosis.

Cao J, Arulanandam R, Vultur A, Preston T, Jaronczyk K, Tomai E, Zandi K, Raptis L.

Mol Carcinog. 2005 May;43(1):38-50.

PMID:
15768386
48.

Transfection techniques affecting Stat3 activity levels.

Arulanandam R, Vultur A, Raptis L.

Anal Biochem. 2005 Mar 1;338(1):83-9.

PMID:
15707938
49.

Cell-to-cell adhesion modulates Stat3 activity in normal and breast carcinoma cells.

Vultur A, Cao J, Arulanandam R, Turkson J, Jove R, Greer P, Craig A, Elliott B, Raptis L.

Oncogene. 2004 Apr 8;23(15):2600-16.

PMID:
15007380
50.

In situ electroporation of radioactive compounds into adherent cells.

Tomai E, Vultur A, Balboa V, Hsu T, Brownell HL, Firth KL, Raptis L.

DNA Cell Biol. 2003 May;22(5):339-46.

PMID:
12941161

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