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Items: 27

1.

Genetic Ablation of TASK-1 (Tandem of P Domains in a Weak Inward Rectifying K+ Channel-Related Acid-Sensitive K+ Channel-1) (K2P3.1) K+ Channels Suppresses Atrial Fibrillation and Prevents Electrical Remodeling.

Schmidt C, Wiedmann F, Beyersdorf C, Zhao Z, El-Battrawy I, Lan H, Szabo G, Li X, Lang S, Korkmaz-Icöz S, Rapti K, Jungmann A, Ratte A, Müller OJ, Karck M, Seemann G, Akin I, Borggrefe M, Zhou XB, Katus HA, Thomas D.

Circ Arrhythm Electrophysiol. 2019 Sep;12(9):e007465. doi: 10.1161/CIRCEP.119.007465. Epub 2019 Sep 13.

PMID:
31514528
2.

Cell-specific CRISPR-Cas9 activation by microRNA-dependent expression of anti-CRISPR proteins.

Hoffmann MD, Aschenbrenner S, Grosse S, Rapti K, Domenger C, Fakhiri J, Mastel M, Börner K, Eils R, Grimm D, Niopek D.

Nucleic Acids Res. 2019 Jul 26;47(13):e75. doi: 10.1093/nar/gkz271.

3.

Comprehensive plasma and tissue profiling reveals systemic metabolic alterations in cardiac hypertrophy and failure.

Müller OJ, Heckmann MB, Ding L, Rapti K, Rangrez AY, Gerken T, Christiansen N, Rennefahrt UEE, Witt H, González Maldonado S, Ternes P, Schwab DM, Ruf T, Hille S, Remes A, Jungmann A, Weis TM, Kreußer JS, Gröne HJ, Backs J, Schatz P, Katus HA, Frey N.

Cardiovasc Res. 2019 Jul 1;115(8):1296-1305. doi: 10.1093/cvr/cvy274.

PMID:
30418544
4.

Ion Channel Dysfunctions in Dilated Cardiomyopathy in Limb-Girdle Muscular Dystrophy.

El-Battrawy I, Zhao Z, Lan H, Li X, Yücel G, Lang S, Sattler K, Schünemann JD, Zimmermann WH, Cyganek L, Utikal J, Wieland T, Bieback K, Bauer R, Ratte A, Pribe-Wolferts R, Rapti K, Nowak D, Wittig J, Thomas D, Most P, Katus HA, Ravens U, Schmidt C, Borggrefe M, Zhou XB, Müller OJ, Akin I.

Circ Genom Precis Med. 2018 Mar;11(3):e001893. doi: 10.1161/CIRCGEN.117.001893.

PMID:
29545480
5.

Identification of circular RNAs with host gene-independent expression in human model systems for cardiac differentiation and disease.

Siede D, Rapti K, Gorska AA, Katus HA, Altmüller J, Boeckel JN, Meder B, Maack C, Völkers M, Müller OJ, Backs J, Dieterich C.

J Mol Cell Cardiol. 2017 Aug;109:48-56. doi: 10.1016/j.yjmcc.2017.06.015. Epub 2017 Jul 1.

PMID:
28676412
6.

Opposite effects of catalase and MnSOD ectopic expression on stress induced defects and mortality in the desmin deficient cardiomyopathy model.

Rapti K, Diokmetzidou A, Kloukina I, Milner DJ, Varela A, Davos CH, Capetanaki Y.

Free Radic Biol Med. 2017 Sep;110:206-218. doi: 10.1016/j.freeradbiomed.2017.06.010. Epub 2017 Jun 16.

PMID:
28629836
7.

Cell-Based Measurement of Neutralizing Antibodies Against Adeno-Associated Virus (AAV).

Jungmann A, Müller O, Rapti K.

Methods Mol Biol. 2017;1521:109-126.

PMID:
27910044
8.

AAV9-mediated gene transfer of desmin ameliorates cardiomyopathy in desmin-deficient mice.

Heckmann MB, Bauer R, Jungmann A, Winter L, Rapti K, Strucksberg KH, Clemen CS, Li Z, Schröder R, Katus HA, Müller OJ.

Gene Ther. 2016 Aug;23(8-9):673-9. doi: 10.1038/gt.2016.40. Epub 2016 Apr 21.

9.

Pulmonary Targeting of Adeno-associated Viral Vectors by Next-generation Sequencing-guided Screening of Random Capsid Displayed Peptide Libraries.

Körbelin J, Sieber T, Michelfelder S, Lunding L, Spies E, Hunger A, Alawi M, Rapti K, Indenbirken D, Müller OJ, Pasqualini R, Arap W, Kleinschmidt JA, Trepel M.

Mol Ther. 2016 Jun;24(6):1050-1061. doi: 10.1038/mt.2016.62. Epub 2016 Mar 28.

10.

Locally Targeted Cardiac Gene Delivery by AAV Microbubble Destruction in a Large Animal Model.

Schlegel P, Huditz R, Meinhardt E, Rapti K, Geis N, Most P, Katus HA, Müller OJ, Bekeredjian R, Raake PW.

Hum Gene Ther Methods. 2016 Apr;27(2):71-8. doi: 10.1089/hgtb.2015.120.

PMID:
26971929
11.

Dominant negative Ras attenuates pathological ventricular remodeling in pressure overload cardiac hypertrophy.

Ramos-Kuri M, Rapti K, Mehel H, Zhang S, Dhandapany PS, Liang L, García-Carrancá A, Bobe R, Fischmeister R, Adnot S, Lebeche D, Hajjar RJ, Lipskaia L, Chemaly ER.

Biochim Biophys Acta. 2015 Nov;1853(11 Pt A):2870-84. doi: 10.1016/j.bbamcr.2015.08.006. Epub 2015 Aug 8. Erratum in: Biochim Biophys Acta. 2016 Apr;1863(4):785.

12.

Effectiveness of gene delivery systems for pluripotent and differentiated cells.

Rapti K, Stillitano F, Karakikes I, Nonnenmacher M, Weber T, Hulot JS, Hajjar RJ.

Mol Ther Methods Clin Dev. 2015 Feb 18;2:14067. doi: 10.1038/mtm.2014.67. eCollection 2015.

13.

Cardiac I-1c overexpression with reengineered AAV improves cardiac function in swine ischemic heart failure.

Ishikawa K, Fish KM, Tilemann L, Rapti K, Aguero J, Santos-Gallego CG, Lee A, Karakikes I, Xie C, Akar FG, Shimada YJ, Gwathmey JK, Asokan A, McPhee S, Samulski J, Samulski RJ, Sigg DC, Weber T, Kranias EG, Hajjar RJ.

Mol Ther. 2014 Dec;22(12):2038-45. doi: 10.1038/mt.2014.127. Epub 2014 Jul 15.

14.

Active inhibitor-1 maintains protein hyper-phosphorylation in aging hearts and halts remodeling in failing hearts.

Pritchard TJ, Kawase Y, Haghighi K, Anjak A, Cai W, Jiang M, Nicolaou P, Pylar G, Karakikes I, Rapti K, Rubinstein J, Hajjar RJ, Kranias EG.

PLoS One. 2013 Dec 2;8(12):e80717. doi: 10.1371/journal.pone.0080717. eCollection 2013.

15.

SUMO-1 gene transfer improves cardiac function in a large-animal model of heart failure.

Tilemann L, Lee A, Ishikawa K, Aguero J, Rapti K, Santos-Gallego C, Kohlbrenner E, Fish KM, Kho C, Hajjar RJ.

Sci Transl Med. 2013 Nov 13;5(211):211ra159. doi: 10.1126/scitranslmed.3006487.

16.

Stimulating myocardial regeneration with periostin Peptide in large mammals improves function post-myocardial infarction but increases myocardial fibrosis.

Ladage D, Yaniz-Galende E, Rapti K, Ishikawa K, Tilemann L, Shapiro S, Takewa Y, Muller-Ehmsen J, Schwarz M, Garcia MJ, Sanz J, Hajjar RJ, Kawase Y.

PLoS One. 2013 May 20;8(5):e59656. doi: 10.1371/journal.pone.0059656. Print 2013.

17.

Quantification of AAV particle titers by infrared fluorescence scanning of coomassie-stained sodium dodecyl sulfate-polyacrylamide gels.

Kohlbrenner E, Henckaerts E, Rapti K, Gordon RE, Linden RM, Hajjar RJ, Weber T.

Hum Gene Ther Methods. 2012 Jun;23(3):198-203. doi: 10.1089/hgtb.2012.049. Epub 2012 Jul 20.

18.

Concomitant intravenous nitroglycerin with intracoronary delivery of AAV1.SERCA2a enhances gene transfer in porcine hearts.

Karakikes I, Hadri L, Rapti K, Ladage D, Ishikawa K, Tilemann L, Yi GH, Morel C, Gwathmey JK, Zsebo K, Weber T, Kawase Y, Hajjar RJ.

Mol Ther. 2012 Mar;20(3):565-71. doi: 10.1038/mt.2011.268. Epub 2012 Jan 3.

19.

Neutralizing antibodies against AAV serotypes 1, 2, 6, and 9 in sera of commonly used animal models.

Rapti K, Louis-Jeune V, Kohlbrenner E, Ishikawa K, Ladage D, Zolotukhin S, Hajjar RJ, Weber T.

Mol Ther. 2012 Jan;20(1):73-83. doi: 10.1038/mt.2011.177. Epub 2011 Sep 13.

20.

Aortic implantation of mesenchymal stem cells after aneurysm injury in a porcine model.

Turnbull IC, Hadri L, Rapti K, Sadek M, Liang L, Shin HJ, Costa KD, Marin ML, Hajjar RJ, Faries PL.

J Surg Res. 2011 Sep;170(1):e179-88. doi: 10.1016/j.jss.2011.05.042. Epub 2011 Jul 13.

21.

Targeted gene therapy for the treatment of heart failure.

Rapti K, Chaanine AH, Hajjar RJ.

Can J Cardiol. 2011 May-Jun;27(3):265-83. doi: 10.1016/j.cjca.2011.02.005. Review.

22.

Delivery of gelfoam-enabled cells and vectors into the pericardial space using a percutaneous approach in a porcine model.

Ladage D, Turnbull IC, Ishikawa K, Takewa Y, Rapti K, Morel C, Karakikes I, Hadri L, Müller-Ehmsen J, Costa KD, Hajjar RJ, Kawase Y.

Gene Ther. 2011 Oct;18(10):979-85. doi: 10.1038/gt.2011.52. Epub 2011 Apr 21.

23.

Multimodality imaging of chronic ischemia.

Ishikawa K, Ladage D, Rapti K, Fernandez-Friera L, Maria Garcia-Lopez A, Sanz J, Hajjar RJ, Kawase Y, Garcia MJ.

Cardiol Res Pract. 2010 Oct 20;2011:739702. doi: 10.4061/2011/739702.

24.

Altered spatiotemporal dynamics of the mitochondrial membrane potential in the hypertrophied heart.

Jin H, Nass RD, Joudrey PJ, Lyon AR, Chemaly ER, Rapti K, Akar FG.

Biophys J. 2010 May 19;98(10):2063-71. doi: 10.1016/j.bpj.2010.01.045.

25.

Production of hard-type cheese using free or immobilized freeze-dried kefir cells as a starter culture.

Katechaki E, Panas P, Rapti K, Kandilogiannakis L, Koutinas AA.

J Agric Food Chem. 2008 Jul 9;56(13):5316-23. doi: 10.1021/jf703585y. Epub 2008 Jun 10.

PMID:
18540611
26.

Alterations in the heart mitochondrial proteome in a desmin null heart failure model.

Fountoulakis M, Soumaka E, Rapti K, Mavroidis M, Tsangaris G, Maris A, Weisleder N, Capetanaki Y.

J Mol Cell Cardiol. 2005 Mar;38(3):461-74.

PMID:
15733906
27.

Polytene chromosomes as tools in the genetic analysis of the Mediterranean fruit fly, Ceratitis capitata.

Gariou-Papalexiou A, Gourzi P, Delprat A, Kritikou D, Rapti K, Chrysanthakopoulou B, Mintzas A, Zacharopoulou A.

Genetica. 2002 Sep;116(1):59-71. Review. No abstract available.

PMID:
12484526

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