Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 60

1.

The Hidden Conundrum of Phosphoinositide Signaling in Cancer.

Thapa N, Tan X, Choi S, Lambert PF, Rapraeger AC, Anderson RA.

Trends Cancer. 2016 Jul;2(7):378-390. Epub 2016 Jun 20. Review.

2.

Heparanase regulation of cancer, autophagy and inflammation: new mechanisms and targets for therapy.

Sanderson RD, Elkin M, Rapraeger AC, Ilan N, Vlodavsky I.

FEBS J. 2017 Jan;284(1):42-55. doi: 10.1111/febs.13932. Epub 2016 Nov 16. Review.

3.

Syndecan-1 (CD138) Suppresses Apoptosis in Multiple Myeloma by Activating IGF1 Receptor: Prevention by SynstatinIGF1R Inhibits Tumor Growth.

Beauvais DM, Jung O, Yang Y, Sanderson RD, Rapraeger AC.

Cancer Res. 2016 Sep 1;76(17):4981-93. doi: 10.1158/0008-5472.CAN-16-0232. Epub 2016 Jun 30.

4.

Heparanase-induced shedding of syndecan-1/CD138 in myeloma and endothelial cells activates VEGFR2 and an invasive phenotype: prevention by novel synstatins.

Jung O, Trapp-Stamborski V, Purushothaman A, Jin H, Wang H, Sanderson RD, Rapraeger AC.

Oncogenesis. 2016 Feb 29;5:e202. doi: 10.1038/oncsis.2016.5.

5.

Stress-Induced EGFR Trafficking: Mechanisms, Functions, and Therapeutic Implications.

Tan X, Lambert PF, Rapraeger AC, Anderson RA.

Trends Cell Biol. 2016 May;26(5):352-366. doi: 10.1016/j.tcb.2015.12.006. Epub 2016 Jan 27. Review.

7.

Cytoplasmic domain interactions of syndecan-1 and syndecan-4 with α6β4 integrin mediate human epidermal growth factor receptor (HER1 and HER2)-dependent motility and survival.

Wang H, Jin H, Beauvais DM, Rapraeger AC.

J Biol Chem. 2014 Oct 31;289(44):30318-32. doi: 10.1074/jbc.M114.586438. Epub 2014 Sep 8.

8.

Synstatin: a selective inhibitor of the syndecan-1-coupled IGF1R-αvβ3 integrin complex in tumorigenesis and angiogenesis.

Rapraeger AC.

FEBS J. 2013 May;280(10):2207-15. doi: 10.1111/febs.12160. Epub 2013 Feb 24. Review.

10.

Transmembrane and extracellular domains of syndecan-1 have distinct functions in regulating lung epithelial migration and adhesion.

Altemeier WA, Schlesinger SY, Buell CA, Brauer R, Rapraeger AC, Parks WC, Chen P.

J Biol Chem. 2012 Oct 12;287(42):34927-35. doi: 10.1074/jbc.M112.376814. Epub 2012 Aug 30.

11.

Syndecan-1 couples the insulin-like growth factor-1 receptor to inside-out integrin activation.

Beauvais DM, Rapraeger AC.

J Cell Sci. 2010 Nov 1;123(Pt 21):3796-807. doi: 10.1242/jcs.067645.

12.

Focus on molecules: syndecan-1.

Zhang Y, McKown RL, Raab RW, Rapraeger AC, Laurie GW.

Exp Eye Res. 2011 Oct;93(4):329-30. doi: 10.1016/j.exer.2010.06.008. Epub 2010 Jun 23. No abstract available.

13.

Interaction of syndecan and alpha6beta4 integrin cytoplasmic domains: regulation of ErbB2-mediated integrin activation.

Wang H, Leavitt L, Ramaswamy R, Rapraeger AC.

J Biol Chem. 2010 Apr 30;285(18):13569-79. doi: 10.1074/jbc.M110.102137. Epub 2010 Feb 24.

14.

Heparanase-enhanced shedding of syndecan-1 by myeloma cells promotes endothelial invasion and angiogenesis.

Purushothaman A, Uyama T, Kobayashi F, Yamada S, Sugahara K, Rapraeger AC, Sanderson RD.

Blood. 2010 Mar 25;115(12):2449-57. doi: 10.1182/blood-2009-07-234757. Epub 2010 Jan 22.

15.

Syndecan-1 regulates alphavbeta3 and alphavbeta5 integrin activation during angiogenesis and is blocked by synstatin, a novel peptide inhibitor.

Beauvais DM, Ell BJ, McWhorter AR, Rapraeger AC.

J Exp Med. 2009 Mar 16;206(3):691-705. doi: 10.1084/jem.20081278. Epub 2009 Mar 2.

16.

Heparanase deglycanation of syndecan-1 is required for binding of the epithelial-restricted prosecretory mitogen lacritin.

Ma P, Beck SL, Raab RW, McKown RL, Coffman GL, Utani A, Chirico WJ, Rapraeger AC, Laurie GW.

J Cell Biol. 2006 Sep 25;174(7):1097-106. Epub 2006 Sep 18. Erratum in: J Cell Biol. 2011 Jan 24;192(2):365.

17.

Heparan sulfate-related oligosaccharides in ternary complex formation with fibroblast growth factors 1 and 2 and their receptors.

Jastrebova N, Vanwildemeersch M, Rapraeger AC, Giménez-Gallego G, Lindahl U, Spillmann D.

J Biol Chem. 2006 Sep 15;281(37):26884-92. Epub 2006 Jun 28.

18.

Syndecan-1 regulates alphavbeta5 integrin activity in B82L fibroblasts.

McQuade KJ, Beauvais DM, Burbach BJ, Rapraeger AC.

J Cell Sci. 2006 Jun 15;119(Pt 12):2445-56. Epub 2006 May 23.

19.

HSulf-1 and HSulf-2 are potent inhibitors of myeloma tumor growth in vivo.

Dai Y, Yang Y, MacLeod V, Yue X, Rapraeger AC, Shriver Z, Venkataraman G, Sasisekharan R, Sanderson RD.

J Biol Chem. 2005 Dec 2;280(48):40066-73. Epub 2005 Sep 27.

20.

Regulation of fibroblast growth factor-2 activity by human ovarian cancer tumor endothelium.

Whitworth MK, Backen AC, Clamp AR, Wilson G, McVey R, Friedl A, Rapraeger AC, David G, McGown A, Slade RJ, Gallagher JT, Jayson GC.

Clin Cancer Res. 2005 Jun 15;11(12):4282-8.

21.

The syndecan-1 ectodomain regulates alphavbeta3 integrin activity in human mammary carcinoma cells.

Beauvais DM, Burbach BJ, Rapraeger AC.

J Cell Biol. 2004 Oct 11;167(1):171-81.

22.

Syndecan-1 ectodomain regulates matrix-dependent signaling in human breast carcinoma cells.

Burbach BJ, Ji Y, Rapraeger AC.

Exp Cell Res. 2004 Oct 15;300(1):234-47.

PMID:
15383330
23.

Cell-surface heparan sulfate proteoglycans potentiate chordin antagonism of bone morphogenetic protein signaling and are necessary for cellular uptake of chordin.

Jasuja R, Allen BL, Pappano WN, Rapraeger AC, Greenspan DS.

J Biol Chem. 2004 Dec 3;279(49):51289-97. Epub 2004 Sep 20.

24.

Essential and separable roles for Syndecan-3 and Syndecan-4 in skeletal muscle development and regeneration.

Cornelison DD, Wilcox-Adelman SA, Goetinck PF, Rauvala H, Rapraeger AC, Olwin BB.

Genes Dev. 2004 Sep 15;18(18):2231-6.

25.

A polymer scaffold for protein oligomerization.

Griffith BR, Allen BL, Rapraeger AC, Kiessling LL.

J Am Chem Soc. 2004 Feb 18;126(6):1608-9.

PMID:
14871072
26.

Syndecans in tumor cell adhesion and signaling.

Beauvais DM, Rapraeger AC.

Reprod Biol Endocrinol. 2004 Jan 7;2:3. Review.

27.
28.
29.

Syndecan-1 transmembrane and extracellular domains have unique and distinct roles in cell spreading.

McQuade KJ, Rapraeger AC.

J Biol Chem. 2003 Nov 21;278(47):46607-15. Epub 2003 Sep 14.

30.

Syndecan-1 accumulates in lysosomes of poorly differentiated breast carcinoma cells.

Burbach BJ, Friedl A, Mundhenke C, Rapraeger AC.

Matrix Biol. 2003 Apr;22(2):163-77.

PMID:
12782143
31.
32.

Heparan sulfate-growth factor interactions.

Rapraeger AC.

Methods Cell Biol. 2002;69:83-109. No abstract available.

PMID:
12071011
33.
34.

Role of heparan sulfate as a tissue-specific regulator of FGF-4 and FGF receptor recognition.

Allen BL, Filla MS, Rapraeger AC.

J Cell Biol. 2001 Nov 26;155(5):845-58. Epub 2001 Nov 26.

35.

Tissue-specific binding by FGF and FGF receptors to endogenous heparan sulfates.

Friedl A, Filla M, Rapraeger AC.

Methods Mol Biol. 2001;171:535-46. No abstract available.

PMID:
11450267
36.

Molecular interactions of syndecans during development.

Rapraeger AC.

Semin Cell Dev Biol. 2001 Apr;12(2):107-16. Review.

PMID:
11292376
37.

Syndecan-1 signals independently of beta1 integrins during Raji cell spreading.

Lebakken CS, McQuade KJ, Rapraeger AC.

Exp Cell Res. 2000 Sep 15;259(2):315-25.

PMID:
10964499
38.

Syndecan-regulated receptor signaling.

Rapraeger AC.

J Cell Biol. 2000 May 29;149(5):995-8. Review. No abstract available.

39.
40.
41.

Molecular interactions of the syndecan core proteins.

Rapraeger AC, Ott VL.

Curr Opin Cell Biol. 1998 Oct;10(5):620-8. Review.

PMID:
9818173
42.
43.

The cell surface proteoglycan syndecan-1 mediates fibroblast growth factor-2 binding and activity.

Filla MS, Dam P, Rapraeger AC.

J Cell Physiol. 1998 Mar;174(3):310-21.

PMID:
9462693
44.

Identification of an adhesion site within the syndecan-4 extracellular protein domain.

McFall AJ, Rapraeger AC.

J Biol Chem. 1997 May 16;272(20):12901-4.

46.

Pervanadate activation of intracellular kinases leads to tyrosine phosphorylation and shedding of syndecan-1.

Reiland J, Ott VL, Lebakken CS, Yeaman C, McCarthy J, Rapraeger AC.

Biochem J. 1996 Oct 1;319 ( Pt 1):39-47.

47.
48.

Syndecan-1 mediates cell spreading in transfected human lymphoblastoid (Raji) cells.

Lebakken CS, Rapraeger AC.

J Cell Biol. 1996 Mar;132(6):1209-21.

49.
50.

Role of FGFs in skeletal muscle and limb development.

Olwin BB, Arthur K, Hannon K, Hein P, McFall A, Riley B, Szebenyi G, Zhou Z, Zuber ME, Rapraeger AC, et al.

Mol Reprod Dev. 1994 Sep;39(1):90-100; discussion 100-1. Review.

PMID:
7999366

Supplemental Content

Loading ...
Support Center