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Short-term effects of airport-associated ultrafine particle exposure on lung function and inflammation in adults with asthma.

Habre R, Zhou H, Eckel SP, Enebish T, Fruin S, Bastain T, Rappaport E, Gilliland F.

Environ Int. 2018 Sep;118:48-59. doi: 10.1016/j.envint.2018.05.031. Epub 2018 May 26.


Significance of green granules in neutrophils and monocytes.

Gorup T, Cohen AT, Sybenga AB, Rappaport ES.

Proc (Bayl Univ Med Cent). 2017 Dec 29;31(1):94-96. doi: 10.1080/08998280.2017.1391045. eCollection 2018 Jan.


Genetic and epigenetic susceptibility of airway inflammation to PM2.5 in school children: new insights from quantile regression.

Zhang Y, Salam MT, Berhane K, Eckel SP, Rappaport EB, Linn WS, Habre R, Bastain TM, Gilliland FD.

Environ Health. 2017 Aug 18;16(1):88. doi: 10.1186/s12940-017-0285-6.


Bayesian estimation of physiological parameters governing a dynamic two-compartment model of exhaled nitric oxide.

Muchmore P, Rappaport EB, Eckel SP.

Physiol Rep. 2017 Aug;5(15). pii: e13276. doi: 10.14814/phy2.13276.


Constrained Mixed-Effect Models with Ensemble Learning for Prediction of Nitrogen Oxides Concentrations at High Spatiotemporal Resolution.

Li L, Lurmann F, Habre R, Urman R, Rappaport E, Ritz B, Chen JC, Gilliland FD, Wu J.

Environ Sci Technol. 2017 Sep 5;51(17):9920-9929. doi: 10.1021/acs.est.7b01864. Epub 2017 Aug 11.


Telehealth Support of Managed Care for a Correctional System: The Open Architecture Telehealth Model.

Rappaport ES, Reynolds HN, Baucom S, Lehman TM.

Telemed J E Health. 2018 Jan;24(1):54-60. doi: 10.1089/tmj.2016.0275. Epub 2017 Jul 6.


Genome-wide TOP2A DNA cleavage is biased toward translocated and highly transcribed loci.

Yu X, Davenport JW, Urtishak KA, Carillo ML, Gosai SJ, Kolaris CP, Byl JAW, Rappaport EF, Osheroff N, Gregory BD, Felix CA.

Genome Res. 2017 Jul;27(7):1238-1249. doi: 10.1101/gr.211615.116. Epub 2017 Apr 6.


HnRNPA2 is a novel histone acetyltransferase that mediates mitochondrial stress-induced nuclear gene expression.

Guha M, Srinivasan S, Guja K, Mejia E, Garcia-Diaz M, Johnson FB, Ruthel G, Kaufman BA, Rappaport EF, Glineburg MR, Fang JK, Klein Szanto A, Nakagawa H, Basha J, Kundu T, Avadhani NG.

Cell Discov. 2016 Dec 6;2:16045. eCollection 2016.


The type 2 diabetes presumed causal variant within TCF7L2 resides in an element that controls the expression of ACSL5.

Xia Q, Chesi A, Manduchi E, Johnston BT, Lu S, Leonard ME, Parlin UW, Rappaport EF, Huang P, Wells AD, Blobel GA, Johnson ME, Grant SFA.

Diabetologia. 2016 Nov;59(11):2360-2368. doi: 10.1007/s00125-016-4077-2. Epub 2016 Aug 18.


The next generation of target capture technologies - large DNA fragment enrichment and sequencing determines regional genomic variation of high complexity.

Dapprich J, Ferriola D, Mackiewicz K, Clark PM, Rappaport E, D'Arcy M, Sasson A, Gai X, Schug J, Kaestner KH, Monos D.

BMC Genomics. 2016 Jul 9;17:486. doi: 10.1186/s12864-016-2836-6.


Unique Familial MLL(KMT2A)-Rearranged Precursor B-Cell Infant Acute Lymphoblastic Leukemia in Non-twin Siblings.

Urtishak KA, Robinson BW, Rappaport EF, Sarezky MD, Biegel JA, Nichols KE, Wilmoth DM, Wang LS, Stern JW, Felix CA.

Pediatr Blood Cancer. 2016 Jul;63(7):1175-80. doi: 10.1002/pbc.25957. Epub 2016 Mar 21.


Traffic-related air pollution and alveolar nitric oxide in southern California children.

Eckel SP, Zhang Z, Habre R, Rappaport EB, Linn WS, Berhane K, Zhang Y, Bastain TM, Gilliland FD.

Eur Respir J. 2016 May;47(5):1348-56. doi: 10.1183/13993003.01176-2015. Epub 2016 Jan 21.


Erratum to: A de novo whole gene deletion of XIAP detected by exome sequencing analysis in very early onset inflammatory bowel disease: a case report.

Kelsen JR, Dawany N, Martinez A, Grochowski CM, Maurer K, Rappaport E, Piccoli DA, Baldassano RN, Mamula P, Sullivan KE, Devoto M.

BMC Gastroenterol. 2015 Dec 18;15:179. doi: 10.1186/s12876-015-0412-1. No abstract available.


A de novo whole gene deletion of XIAP detected by exome sequencing analysis in very early onset inflammatory bowel disease: a case report.

Kelsen JR, Dawany N, Martinez A, Grochowski CM, Maurer K, Rappaport E, Piccoli DA, Baldassano RN, Mamula P, Sullivan KE, Devoto M.

BMC Gastroenterol. 2015 Nov 18;15:160. doi: 10.1186/s12876-015-0394-z. Erratum in: BMC Gastroenterol. 2015;15:179. Martinez, Alejuandro [corrected to Martinez, Alejandro].


Generation of a mouse model of atypical teratoid/rhabdoid tumor of the central nervous system through combined deletion of Snf5 and p53.

Ng JM, Martinez D, Marsh ED, Zhang Z, Rappaport E, Santi M, Curran T.

Cancer Res. 2015 Nov 1;75(21):4629-39. doi: 10.1158/0008-5472.CAN-15-0874. Epub 2015 Sep 11.


Childhood determination of Hodgkin lymphoma among U.S. servicemen.

Mack TM, Norman JE Jr, Rappaport E, Cozen W.

Cancer Epidemiol Biomarkers Prev. 2015 Nov;24(11):1707-15. doi: 10.1158/1055-9965.EPI-15-0145. Epub 2015 Aug 31.


Determinants of Children's Exhaled Nitric Oxide: New Insights from Quantile Regression.

Zhang Y, Berhane K, Eckel SP, Salam MT, Linn WS, Rappaport EB, Bastain TM, Gilliland FD.

PLoS One. 2015 Jul 27;10(7):e0130505. doi: 10.1371/journal.pone.0130505. eCollection 2015.


Exome sequencing analysis reveals variants in primary immunodeficiency genes in patients with very early onset inflammatory bowel disease.

Kelsen JR, Dawany N, Moran CJ, Petersen BS, Sarmady M, Sasson A, Pauly-Hubbard H, Martinez A, Maurer K, Soong J, Rappaport E, Franke A, Keller A, Winter HS, Mamula P, Piccoli D, Artis D, Sonnenberg GF, Daly M, Sullivan KE, Baldassano RN, Devoto M.

Gastroenterology. 2015 Nov;149(6):1415-24. doi: 10.1053/j.gastro.2015.07.006. Epub 2015 Jul 17.


RNA Biosignatures in Adolescent Patients in a Pediatric Emergency Department With Pelvic Inflammatory Disease.

Balamuth F, Zhang Z, Rappaport E, Hayes K, Mollen C, Sullivan KE.

Pediatr Emerg Care. 2015 Jul;31(7):465-72. doi: 10.1097/PEC.0000000000000483.


Association of improved air quality with lung development in children.

Gauderman WJ, Urman R, Avol E, Berhane K, McConnell R, Rappaport E, Chang R, Lurmann F, Gilliland F.

N Engl J Med. 2015 Mar 5;372(10):905-13. doi: 10.1056/NEJMoa1414123.


ALK mutations confer differential oncogenic activation and sensitivity to ALK inhibition therapy in neuroblastoma.

Bresler SC, Weiser DA, Huwe PJ, Park JH, Krytska K, Ryles H, Laudenslager M, Rappaport EF, Wood AC, McGrady PW, Hogarty MD, London WB, Radhakrishnan R, Lemmon MA, Mossé YP.

Cancer Cell. 2014 Nov 10;26(5):682-94. doi: 10.1016/j.ccell.2014.09.019. Epub 2014 Nov 10.


Progressive increase in mtDNA 3243A>G heteroplasmy causes abrupt transcriptional reprogramming.

Picard M, Zhang J, Hancock S, Derbeneva O, Golhar R, Golik P, O'Hearn S, Levy S, Potluri P, Lvova M, Davila A, Lin CS, Perin JC, Rappaport EF, Hakonarson H, Trounce IA, Procaccio V, Wallace DC.

Proc Natl Acad Sci U S A. 2014 Sep 23;111(38):E4033-42. doi: 10.1073/pnas.1414028111. Epub 2014 Sep 5.


Spirometry effects on conventional and multiple flow exhaled nitric oxide in children.

Eckel SP, Linn WS, Salam MT, Bastain TM, Zhang Y, Rappaport EB, Liu M, Berhane K.

J Asthma. 2015 Mar;52(2):198-204. doi: 10.3109/02770903.2014.954292. Epub 2014 Aug 28.


Dielectrophoretic capture and genetic analysis of single neuroblastoma tumor cells.

Carpenter EL, Rader J, Ruden J, Rappaport EF, Hunter KN, Hallberg PL, Krytska K, O'Dwyer PJ, Mosse YP.

Front Oncol. 2014 Jul 31;4:201. doi: 10.3389/fonc.2014.00201. eCollection 2014.


Longitudinal effects of air pollution on exhaled nitric oxide: the Children's Health Study.

Berhane K, Zhang Y, Salam MT, Eckel SP, Linn WS, Rappaport EB, Bastain TM, Lurmann F, Gilliland FD.

Occup Environ Med. 2014 Jul;71(7):507-13. doi: 10.1136/oemed-2013-101874. Epub 2014 Apr 2.


Spatial Variation in Particulate Matter Components over a Large Urban Area.

Fruin S, Urman R, Lurmann F, McConnell R, Gauderman J, Rappaport E, Franklin M, Gilliland FD, Shafer M, Gorski P, Avol E.

Atmos Environ (1994). 2014 Feb 1;83:211-219.


Estimation of parameters in the two-compartment model for exhaled nitric oxide.

Eckel SP, Linn WS, Berhane K, Rappaport EB, Salam MT, Zhang Y, Gilliland FD.

PLoS One. 2014 Jan 17;9(1):e85471. doi: 10.1371/journal.pone.0085471. eCollection 2014.


Associations of children's lung function with ambient air pollution: joint effects of regional and near-roadway pollutants.

Urman R, McConnell R, Islam T, Avol EL, Lurmann FW, Vora H, Linn WS, Rappaport EB, Gilliland FD, Gauderman WJ.

Thorax. 2014 Jun;69(6):540-7. doi: 10.1136/thoraxjnl-2012-203159. Epub 2013 Nov 19.


S(+)-ibuprofen destabilizes MYC/MYCN and AKT, increases p53 expression, and induces unfolded protein response and favorable phenotype in neuroblastoma cell lines.

Ikegaki N, Hicks SL, Regan PL, Jacobs J, Jumbo AS, Leonhardt P, Rappaport EF, Tang XX.

Int J Oncol. 2014 Jan;44(1):35-43. doi: 10.3892/ijo.2013.2148. Epub 2013 Oct 25.


Histone H2AX suppresses translocations in lymphomas of Eμ-c-Myc transgenic mice that contain a germline amplicon of tumor-promoting genes.

Fusello A, Horowitz J, Yang-Iott K, Brady BL, Yin B, Rowh MA, Rappaport E, Bassing CH.

Cell Cycle. 2013 Sep 1;12(17):2867-75. doi: 10.4161/cc.25922. Epub 2013 Aug 8.


Primary respiratory chain disease causes tissue-specific dysregulation of the global transcriptome and nutrient-sensing signaling network.

Zhang Z, Tsukikawa M, Peng M, Polyak E, Nakamaru-Ogiso E, Ostrovsky J, McCormack S, Place E, Clarke C, Reiner G, McCormick E, Rappaport E, Haas R, Baur JA, Falk MJ.

PLoS One. 2013 Jul 24;8(7):e69282. doi: 10.1371/journal.pone.0069282. Print 2013.


Multiple-flow exhaled nitric oxide, allergy, and asthma in a population of older children.

Linn WS, Rappaport EB, Eckel SP, Berhane KT, Zhang Y, Salam MT, Bastain TM, Gilliland FD.

Pediatr Pulmonol. 2013 Sep;48(9):885-96. doi: 10.1002/ppul.22708. Epub 2013 May 17.


Transient treatment with epigenetic modifiers yields stable neuroblastoma stem cells resembling aggressive large-cell neuroblastomas.

Ikegaki N, Shimada H, Fox AM, Regan PL, Jacobs JR, Hicks SL, Rappaport EF, Tang XX.

Proc Natl Acad Sci U S A. 2013 Apr 9;110(15):6097-102. doi: 10.1073/pnas.1118262110. Epub 2013 Mar 11.


Network-based analysis of multivariate gene expression data.

Zhi W, Minturn J, Rappaport E, Brodeur G, Li H.

Methods Mol Biol. 2013;972:121-39. doi: 10.1007/978-1-60327-337-4_8.


Mitochondrial disease genetic diagnostics: optimized whole-exome analysis for all MitoCarta nuclear genes and the mitochondrial genome.

Falk MJ, Pierce EA, Consugar M, Xie MH, Guadalupe M, Hardy O, Rappaport EF, Wallace DC, LeProust E, Gai X.

Discov Med. 2012 Dec;14(79):389-99.


Re-sequencing of ankyrin 3 exon 48 and case-control association analysis of rare variants in bipolar disorder type I.

Doyle GA, Lai AT, Chou AD, Wang MJ, Gai X, Rappaport EF, Berrettini WH.

Bipolar Disord. 2012 Dec;14(8):809-21. doi: 10.1111/bdi.12002. Epub 2012 Sep 11.


Using routinely collected growth data to assess a school-based obesity prevention strategy.

Rappaport EB, Daskalakis C, Sendecki JA.

Int J Obes (Lond). 2013 Jan;37(1):79-85. doi: 10.1038/ijo.2012.126. Epub 2012 Sep 4.


Common variation at BARD1 results in the expression of an oncogenic isoform that influences neuroblastoma susceptibility and oncogenicity.

Bosse KR, Diskin SJ, Cole KA, Wood AC, Schnepp RW, Norris G, Nguyen le B, Jagannathan J, Laquaglia M, Winter C, Diamond M, Hou C, Attiyeh EF, Mosse YP, Pineros V, Dizin E, Zhang Y, Asgharzadeh S, Seeger RC, Capasso M, Pawel BR, Devoto M, Hakonarson H, Rappaport EF, Irminger-Finger I, Maris JM.

Cancer Res. 2012 Apr 15;72(8):2068-78. doi: 10.1158/0008-5472.CAN-11-3703. Epub 2012 Feb 20.


Preclinical evaluation of pemetrexed in pediatric solid tumors.

Norris RE, Rappaport EF, Adamson PC.

Pediatr Blood Cancer. 2011 Dec 15;57(7):1233-5. doi: 10.1002/pbc.23286. Epub 2011 Aug 17.


Residential traffic-related pollution exposures and exhaled nitric oxide in the children's health study.

Eckel SP, Berhane K, Salam MT, Rappaport EB, Linn WS, Bastain TM, Zhang Y, Lurmann F, Avol EL, Gilliland FD.

Environ Health Perspect. 2011 Oct;119(10):1472-7. doi: 10.1289/ehp.1103516. Epub 2011 Jun 27.


Obesity and other predictors of absenteeism in Philadelphia school children.

Rappaport EB, Daskalakis C, Andrel J.

J Sch Health. 2011 Jun;81(6):341-4. doi: 10.1111/j.1746-1561.2011.00599.x.


Quantitative trait loci for electrical seizure threshold mapped in C57BLKS/J and C57BL/10SnJ mice.

Ferraro TN, Smith GG, Ballard D, Zhao H, Schwebel CL, Gupta A, Rappaport EF, Ruiz SE, Lohoff FW, Doyle GA, Berrettini WH, Buono RJ.

Genes Brain Behav. 2011 Apr;10(3):309-15. doi: 10.1111/j.1601-183X.2010.00668.x. Epub 2010 Dec 22.


High-Resolution genomic arrays identify CNVs that phenocopy the chromosome 22q11.2 deletion syndrome.

Busse T, Graham JM Jr, Feldman G, Perin J, Catherwood A, Knowlton R, Rappaport EF, Emanuel B, Driscoll DA, Saitta SC.

Hum Mutat. 2011 Jan;32(1):91-7. doi: 10.1002/humu.21395.


Genetic variations in nitric oxide synthase and arginase influence exhaled nitric oxide levels in children.

Salam MT, Bastain TM, Rappaport EB, Islam T, Berhane K, Gauderman WJ, Gilliland FD.

Allergy. 2011 Mar;66(3):412-9. doi: 10.1111/j.1398-9995.2010.02492.x. Epub 2010 Oct 6.


The effect of ambient air pollution on exhaled nitric oxide in the Children's Health Study.

Berhane K, Zhang Y, Linn WS, Rappaport EB, Bastain TM, Salam MT, Islam T, Lurmann F, Gilliland FD.

Eur Respir J. 2011 May;37(5):1029-36. doi: 10.1183/09031936.00081410. Epub 2010 Oct 14.


Biological effects of induced MYCN hyper-expression in MYCN-amplified neuroblastomas.

Torres J, Regan PL, Edo R, Leonhardt P, Jeng EI, Rappaport EF, Ikegaki N, Tang XX.

Int J Oncol. 2010 Oct;37(4):983-91.


Exhaled nitric oxide, susceptibility and new-onset asthma in the Children's Health Study.

Bastain TM, Islam T, Berhane KT, McConnell RS, Rappaport EB, Salam MT, Linn WS, Avol EL, Zhang Y, Gilliland FD.

Eur Respir J. 2011 Mar;37(3):523-31. doi: 10.1183/09031936.00021210. Epub 2010 Jul 15.


Serial transcriptome analysis and cross-species integration identifies centromere-associated protein E as a novel neuroblastoma target.

Balamuth NJ, Wood A, Wang Q, Jagannathan J, Mayes P, Zhang Z, Chen Z, Rappaport E, Courtright J, Pawel B, Weber B, Wooster R, Sekyere EO, Marshall GM, Maris JM.

Cancer Res. 2010 Apr 1;70(7):2749-58. doi: 10.1158/0008-5472.CAN-09-3844. Epub 2010 Mar 16.


CNV Workshop: an integrated platform for high-throughput copy number variation discovery and clinical diagnostics.

Gai X, Perin JC, Murphy K, O'Hara R, D'arcy M, Wenocur A, Xie HM, Rappaport EF, Shaikh TH, White PS.

BMC Bioinformatics. 2010 Feb 4;11:74. doi: 10.1186/1471-2105-11-74.


A de novo 8.8-Mb deletion of 21q21.1-q21.3 in an autistic male with a complex rearrangement involving chromosomes 6, 10, and 21.

Haldeman-Englert CR, Chapman KA, Kruger H, Geiger EA, McDonald-McGinn DM, Rappaport E, Zackai EH, Spinner NB, Shaikh TH.

Am J Med Genet A. 2010 Jan;152A(1):196-202. doi: 10.1002/ajmg.a.33176.

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