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Items: 1 to 50 of 406

1.

Dysregulated protocadherin-pathway activity as an intrinsic defect in induced pluripotent stem cell-derived cortical interneurons from subjects with schizophrenia.

Shao Z, Noh H, Bin Kim W, Ni P, Nguyen C, Cote SE, Noyes E, Zhao J, Parsons T, Park JM, Zheng K, Park JJ, Coyle JT, Weinberger DR, Straub RE, Berman KF, Apud J, Ongur D, Cohen BM, McPhie DL, Rapoport JL, Perlis RH, Lanz TA, Xi HS, Yin C, Huang W, Hirayama T, Fukuda E, Yagi T, Ghosh S, Eggan KC, Kim HY, Eisenberg LM, Moghadam AA, Stanton PK, Cho JH, Chung S.

Nat Neurosci. 2019 Feb;22(2):229-242. doi: 10.1038/s41593-018-0313-z. Epub 2019 Jan 21.

PMID:
30664768
2.

Exome sequencing of sporadic childhood-onset schizophrenia suggests the contribution of X-linked genes in males.

Ambalavanan A, Chaumette B, Zhou S, Xie P, He Q, Spiegelman D, Dionne-Laporte A, Bourassa CV, Therrien M, Rochefort D, Xiong L, Dion PA, Joober R, Rapoport JL, Girard SL, Rouleau GA.

Am J Med Genet B Neuropsychiatr Genet. 2018 Oct 30. doi: 10.1002/ajmg.b.32683. [Epub ahead of print]

PMID:
30378261
3.

Reduced Functional Brain Activation and Connectivity During a Working Memory Task in Childhood-Onset Schizophrenia.

Loeb FF, Zhou X, Craddock KES, Shora L, Broadnax DD, Gochman P, Clasen LS, Lalonde FM, Berman RA, Berman KF, Rapoport JL, Liu S.

J Am Acad Child Adolesc Psychiatry. 2018 Mar;57(3):166-174. doi: 10.1016/j.jaac.2017.12.009. Epub 2017 Dec 28.

4.

Attenuated resting-state functional connectivity in patients with childhood- and adult-onset schizophrenia.

Watsky RE, Gotts SJ, Berman RA, McAdams HM, Zhou X, Greenstein D, Lalonde FM, Gochman P, Clasen LS, Shora L, Ordóñez AE, Gogtay N, Martin A, Barch DM, Rapoport JL, Liu S.

Schizophr Res. 2018 Jan 6. pii: S0920-9964(18)30003-3. doi: 10.1016/j.schres.2018.01.003. [Epub ahead of print]

PMID:
29310911
5.

Symptom dimensions and subgroups in childhood-onset schizophrenia.

Craddock KES, Zhou X, Liu S, Gochman P, Dickinson D, Rapoport JL.

Schizophr Res. 2017 Nov 13. pii: S0920-9964(17)30673-4. doi: 10.1016/j.schres.2017.10.045. [Epub ahead of print]

6.

Good News for Screening for Adult Attention-Deficit/Hyperactivity Disorder.

Shaw P, Ahn K, Rapoport JL.

JAMA Psychiatry. 2017 May 1;74(5):527. doi: 10.1001/jamapsychiatry.2017.0296. No abstract available.

PMID:
28384652
7.

Lack of Gender-Related Differences in Childhood-Onset Schizophrenia.

Ordóñez AE, Loeb FF, Zhou X, Shora L, Berman RA, Broadnax DD, Gochman P, Liu S, Rapoport JL.

J Am Acad Child Adolesc Psychiatry. 2016 Sep;55(9):792-9. doi: 10.1016/j.jaac.2016.05.022. Epub 2016 Jul 1.

8.

Constance E. Lieber, Theodore R. Stanley, and the Enduring Impact of Philanthropy on Psychiatry Research.

Krystal JH, Abi-Dargham A, Akbarian S, Arnsten AFT, Barch DM, Bearden CE, Braff DL, Brown ES, Bullmore ET, Carlezon WA Jr, Carter CS, Cook EH Jr, Daskalakis ZJ, DiLeone RJ, Duman RS, Grace AA, Hariri AR, Harrison PJ, Hiroi N, Kenny PJ, Kleinman JE, Krystal AD, Lewis DA, Lipska BK, Marder SR, Mason GF, Mathalon DH, McClung CA, McDougle CJ, McIntosh AM, McMahon FJ, Mirnics K, Monteggia LM, Narendran R, Nestler EJ, Neumeister A, O'Donovan MC, Öngür D, Pariante CM, Paulus MP, Pearlson G, Phillips ML, Pine DS, Pizzagalli DA, Pletnikov MV, Ragland JD, Rapoport JL, Ressler KJ, Russo SJ, Sanacora G, Sawa A, Schatzberg AF, Shaham Y, Shamay-Tsoory SG, Sklar P, State MW, Stein MB, Strakowski SM, Taylor SF, Turecki G, Turetsky BI, Weissman MM, Zachariou V, Zarate CA Jr, Zubieta JK.

Biol Psychiatry. 2016 Jul 15;80(2):84-86. doi: 10.1016/j.biopsych.2016.05.004. No abstract available.

9.

15q13.3 duplication in two patients with childhood-onset schizophrenia.

Zhou D, Gochman P, Broadnax DD, Rapoport JL, Ahn K.

Am J Med Genet B Neuropsychiatr Genet. 2016 Sep;171(6):777-83. doi: 10.1002/ajmg.b.32439. Epub 2016 Mar 10.

10.

Severity of Cortical Thinning Correlates With Schizophrenia Spectrum Symptoms.

Watsky RE, Pollard KL, Greenstein D, Shora L, Dillard-Broadnax D, Gochman P, Clasen LS, Berman RA, Rapoport JL, Gogtay N, Ordóñez AE.

J Am Acad Child Adolesc Psychiatry. 2016 Feb;55(2):130-136. doi: 10.1016/j.jaac.2015.11.008. Epub 2015 Nov 26.

11.

Strong Treatment Response and High Maintenance Rates of Clozapine in Childhood-Onset Schizophrenia.

Kasoff LI, Ahn K, Gochman P, Broadnax DD, Rapoport JL.

J Child Adolesc Psychopharmacol. 2016 Jun;26(5):428-35. doi: 10.1089/cap.2015.0103. Epub 2016 Jan 19.

12.

Infection and characterization of Toxoplasma gondii in human induced neurons from patients with brain disorders and healthy controls.

Passeri E, Jones-Brando L, Bordón C, Sengupta S, Wilson AM, Primerano A, Rapoport JL, Ishizuka K, Kano S, Yolken RH, Sawa A.

Microbes Infect. 2016 Feb;18(2):153-8. doi: 10.1016/j.micinf.2015.09.023. Epub 2015 Oct 9.

13.

The Influence of Microdeletions and Microduplications of 16p11.2 on Global Transcription Profiles.

Kusenda M, Vacic V, Malhotra D, Rodgers L, Pavon K, Meth J, Kumar RA, Christian SL, Peeters H, Cho SS, Addington A, Rapoport JL, Sebat J.

J Child Neurol. 2015 Dec;30(14):1947-53. doi: 10.1177/0883073815602066. Epub 2015 Sep 20.

14.

Enhanced conversion of induced neuronal cells (iN cells) from human fibroblasts: Utility in uncovering cellular deficits in mental illness-associated chromosomal abnormalities.

Passeri E, Wilson AM, Primerano A, Kondo MA, Sengupta S, Srivastava R, Koga M, Obie C, Zandi PP, Goes FS, Valle D, Rapoport JL, Sawa A, Kano S, Ishizuka K.

Neurosci Res. 2015 Dec;101:57-61. doi: 10.1016/j.neures.2015.07.011. Epub 2015 Aug 7.

15.

Delayed Development of Brain Connectivity in Adolescents With Schizophrenia and Their Unaffected Siblings.

Zalesky A, Pantelis C, Cropley V, Fornito A, Cocchi L, McAdams H, Clasen L, Greenstein D, Rapoport JL, Gogtay N.

JAMA Psychiatry. 2015 Sep;72(9):900-8. doi: 10.1001/jamapsychiatry.2015.0226.

PMID:
26176706
16.

Hippocampal volume change relates to clinical outcome in childhood-onset schizophrenia.

Anvari AA, Friedman LA, Greenstein D, Gochman P, Gogtay N, Rapoport JL.

Psychol Med. 2015;45(12):2667-74. doi: 10.1017/S0033291715000677. Epub 2015 May 4.

PMID:
25936396
17.

Clinical utility of neuronal cells directly converted from fibroblasts of patients for neuropsychiatric disorders: studies of lysosomal storage diseases and channelopathy.

Kano S, Yuan M, Cardarelli RA, Maegawa G, Higurashi N, Gaval-Cruz M, Wilson AM, Tristan C, Kondo MA, Chen Y, Koga M, Obie C, Ishizuka K, Seshadri S, Srivastava R, Kato TA, Horiuchi Y, Sedlak TW, Lee Y, Rapoport JL, Hirose S, Okano H, Valle D, O'Donnell P, Sawa A, Kai M.

Curr Mol Med. 2015;15(2):138-45.

18.

Common polygenic variation and risk for childhood-onset schizophrenia.

Ahn K, An SS, Shugart YY, Rapoport JL.

Mol Psychiatry. 2016 Jan;21(1):94-6. doi: 10.1038/mp.2014.158. Epub 2014 Dec 16.

PMID:
25510512
19.

Striatal shape abnormalities as novel neurodevelopmental endophenotypes in schizophrenia: a longitudinal study.

Chakravarty MM, Rapoport JL, Giedd JN, Raznahan A, Shaw P, Collins DL, Lerch JP, Gogtay N.

Hum Brain Mapp. 2015 Apr;36(4):1458-69. doi: 10.1002/hbm.22715. Epub 2014 Dec 11.

PMID:
25504933
20.

Brain development in ADHD.

Friedman LA, Rapoport JL.

Curr Opin Neurobiol. 2015 Feb;30:106-11. doi: 10.1016/j.conb.2014.11.007. Epub 2014 Dec 9. Review.

PMID:
25500059
21.

Child psychiatry branch of the National Institute of Mental Health longitudinal structural magnetic resonance imaging study of human brain development.

Giedd JN, Raznahan A, Alexander-Bloch A, Schmitt E, Gogtay N, Rapoport JL.

Neuropsychopharmacology. 2015 Jan;40(1):43-9. doi: 10.1038/npp.2014.236. Epub 2014 Sep 8. Review.

22.

Response to Majeske and Kellner.

Driver DI, Rapoport JL, Gogtay N.

Am J Psychiatry. 2014 Sep;171(9):1000. doi: 10.1176/appi.ajp.2014.14050628r. No abstract available.

PMID:
25178754
23.

Modeling a genetic risk for schizophrenia in iPSCs and mice reveals neural stem cell deficits associated with adherens junctions and polarity.

Yoon KJ, Nguyen HN, Ursini G, Zhang F, Kim NS, Wen Z, Makri G, Nauen D, Shin JH, Park Y, Chung R, Pekle E, Zhang C, Towe M, Hussaini SM, Lee Y, Rujescu D, St Clair D, Kleinman JE, Hyde TM, Krauss G, Christian KM, Rapoport JL, Weinberger DR, Song H, Ming GL.

Cell Stem Cell. 2014 Jul 3;15(1):79-91. doi: 10.1016/j.stem.2014.05.003. Erratum in: Cell Stem Cell. 2015 Mar 5;16(3):339.

24.

Management of clozapine-induced fever in a child.

Driver DI, Anvari AA, Peroutka CM, Kataria R, Overman J, Lang D, Tietcheu M, Parker R, Baptiste K, Rapoport JL, Gogtay N.

Am J Psychiatry. 2014 Apr;171(4):398-402. doi: 10.1176/appi.ajp.2013.13070866. No abstract available.

PMID:
24687195
25.

Perspectives on child and adolescent psychiatry from Brazil.

Rapoport JL.

Braz J Psychiatry. 2013;35 Suppl 1:S2. doi: 10.1590/1516-4446-2013-S102. No abstract available.

26.

Childhood onset schizophrenia and early onset schizophrenia spectrum disorders.

Driver DI, Gogtay N, Rapoport JL.

Child Adolesc Psychiatr Clin N Am. 2013 Oct;22(4):539-55. doi: 10.1016/j.chc.2013.04.001. Epub 2013 Jun 18.

27.

Pediatric psychopharmacology: too much or too little?

Rapoport JL.

World Psychiatry. 2013 Jun;12(2):118-23. doi: 10.1002/wps.20028.

28.

High rate of disease-related copy number variations in childhood onset schizophrenia.

Ahn K, Gotay N, Andersen TM, Anvari AA, Gochman P, Lee Y, Sanders S, Guha S, Darvasi A, Glessner JT, Hakonarson H, Lencz T, State MW, Shugart YY, Rapoport JL.

Mol Psychiatry. 2014 May;19(5):568-72. doi: 10.1038/mp.2013.59. Epub 2013 May 21.

29.

Treatments in context: transcranial direct current brain stimulation as a potential treatment in pediatric psychosis.

David CN, Rapoport JL, Gogtay N.

Expert Rev Neurother. 2013 Apr;13(4):447-58. doi: 10.1586/ern.13.29. Review.

30.

Risk factors for neutropenia in clozapine-treated children and adolescents with childhood-onset schizophrenia.

Maher KN, Tan M, Tossell JW, Weisinger B, Gochman P, Miller R, Greenstein D, Overman GP, Rapoport JL, Gogtay N.

J Child Adolesc Psychopharmacol. 2013 Mar;23(2):110-6. doi: 10.1089/cap.2011.0136.

31.

Prevention of schizophrenia: an impossible dream?

Rapoport JL.

Am J Psychiatry. 2013 Mar;170(3):245-7. doi: 10.1176/appi.ajp.2012.12101287. No abstract available.

32.

Delayed white matter growth trajectory in young nonpsychotic siblings of patients with childhood-onset schizophrenia.

Gogtay N, Hua X, Stidd R, Boyle CP, Lee S, Weisinger B, Chavez A, Giedd JN, Clasen L, Toga AW, Rapoport JL, Thompson PM.

Arch Gen Psychiatry. 2012 Sep;69(9):875-84. doi: 10.1001/archgenpsychiatry.2011.2084.

33.

Psychotic symptoms and gray matter deficits in clinical pediatric populations.

Gogtay N, Weisinger B, Bakalar JL, Stidd R, Fernandez de la Vega O, Miller R, Clasen L, Greenstein D, Rapoport JL.

Schizophr Res. 2012 Sep;140(1-3):149-54. doi: 10.1016/j.schres.2012.07.006. Epub 2012 Jul 24.

34.

Microduplications disrupting the MYT1L gene (2p25.3) are associated with schizophrenia.

Lee Y, Mattai A, Long R, Rapoport JL, Gogtay N, Addington AM.

Psychiatr Genet. 2012 Aug;22(4):206-9. doi: 10.1097/YPG.0b013e328353ae3d.

35.

Neurodevelopmental model of schizophrenia: update 2012.

Rapoport JL, Giedd JN, Gogtay N.

Mol Psychiatry. 2012 Dec;17(12):1228-38. doi: 10.1038/mp.2012.23. Epub 2012 Apr 10. Review.

36.

Simple models of human brain functional networks.

Vértes PE, Alexander-Bloch AF, Gogtay N, Giedd JN, Rapoport JL, Bullmore ET.

Proc Natl Acad Sci U S A. 2012 Apr 10;109(15):5868-73. doi: 10.1073/pnas.1111738109. Epub 2012 Mar 30.

37.

Transcriptome profiling of UPF3B/NMD-deficient lymphoblastoid cells from patients with various forms of intellectual disability.

Nguyen LS, Jolly L, Shoubridge C, Chan WK, Huang L, Laumonnier F, Raynaud M, Hackett A, Field M, Rodriguez J, Srivastava AK, Lee Y, Long R, Addington AM, Rapoport JL, Suren S, Hahn CN, Gamble J, Wilkinson MF, Corbett MA, Gecz J.

Mol Psychiatry. 2012 Nov;17(11):1103-15. doi: 10.1038/mp.2011.163. Epub 2011 Dec 20.

38.

The utility of (11)C-arachidonate PET to study in vivo dopaminergic neurotransmission in humans.

Thambisetty M, Gallardo KA, Liow JS, Beason-Held LL, Umhau JC, Bhattacharjee AK, Der M, Herscovitch P, Rapoport JL, Rapoport SI.

J Cereb Blood Flow Metab. 2012 Apr;32(4):676-84. doi: 10.1038/jcbfm.2011.171. Epub 2011 Dec 14.

39.

Genome-wide copy number variation study associates metabotropic glutamate receptor gene networks with attention deficit hyperactivity disorder.

Elia J, Glessner JT, Wang K, Takahashi N, Shtir CJ, Hadley D, Sleiman PM, Zhang H, Kim CE, Robison R, Lyon GJ, Flory JH, Bradfield JP, Imielinski M, Hou C, Frackelton EC, Chiavacci RM, Sakurai T, Rabin C, Middleton FA, Thomas KA, Garris M, Mentch F, Freitag CM, Steinhausen HC, Todorov AA, Reif A, Rothenberger A, Franke B, Mick EO, Roeyers H, Buitelaar J, Lesch KP, Banaschewski T, Ebstein RP, Mulas F, Oades RD, Sergeant J, Sonuga-Barke E, Renner TJ, Romanos M, Romanos J, Warnke A, Walitza S, Meyer J, Pálmason H, Seitz C, Loo SK, Smalley SL, Biederman J, Kent L, Asherson P, Anney RJ, Gaynor JW, Shaw P, Devoto M, White PS, Grant SF, Buxbaum JD, Rapoport JL, Williams NM, Nelson SF, Faraone SV, Hakonarson H.

Nat Genet. 2011 Dec 4;44(1):78-84. doi: 10.1038/ng.1013.

40.

Annual research review: impact of advances in genetics in understanding developmental psychopathology.

Addington AM, Rapoport JL.

J Child Psychol Psychiatry. 2012 May;53(5):510-8. doi: 10.1111/j.1469-7610.2011.02478.x. Epub 2011 Nov 8. Review.

PMID:
22067053
41.

Childhood-onset schizophrenia: the challenge of diagnosis.

Gochman P, Miller R, Rapoport JL.

Curr Psychiatry Rep. 2011 Oct;13(5):321-2. doi: 10.1007/s11920-011-0212-4.

42.

Normalization of cortical gray matter deficits in nonpsychotic siblings of patients with childhood-onset schizophrenia.

Mattai AA, Weisinger B, Greenstein D, Stidd R, Clasen L, Miller R, Tossell JW, Rapoport JL, Gogtay N.

J Am Acad Child Adolesc Psychiatry. 2011 Jul;50(7):697-704. doi: 10.1016/j.jaac.2011.03.016. Epub 2011 Jun 11.

43.

Childhood onset schizophrenia: high rate of visual hallucinations.

David CN, Greenstein D, Clasen L, Gochman P, Miller R, Tossell JW, Mattai AA, Gogtay N, Rapoport JL.

J Am Acad Child Adolesc Psychiatry. 2011 Jul;50(7):681-686.e3. doi: 10.1016/j.jaac.2011.03.020. Epub 2011 Jun 11.

44.

Catechol-o-methyl transferase (COMT) val158met polymorphism and adolescent cortical development in patients with childhood-onset schizophrenia, their non-psychotic siblings, and healthy controls.

Raznahan A, Greenstein D, Lee Y, Long R, Clasen L, Gochman P, Addington A, Giedd JN, Rapoport JL, Gogtay N.

Neuroimage. 2011 Aug 15;57(4):1517-23. doi: 10.1016/j.neuroimage.2011.05.032. Epub 2011 May 15.

45.

A Novel Microduplication in the Neurodevelopmental Gene SRGAP3 That Segregates with Psychotic Illness in the Family of a COS Proband.

Wilson NK, Lee Y, Long R, Hermetz K, Rudd MK, Miller R, Rapoport JL, Addington AM.

Case Rep Genet. 2011;2011:585893. doi: 10.1155/2011/585893. Epub 2011 Sep 12.

46.

Rare mutations in N-methyl-D-aspartate glutamate receptors in autism spectrum disorders and schizophrenia.

Tarabeux J, Kebir O, Gauthier J, Hamdan FF, Xiong L, Piton A, Spiegelman D, Henrion É, Millet B; S2D team, Fathalli F, Joober R, Rapoport JL, DeLisi LE, Fombonne É, Mottron L, Forget-Dubois N, Boivin M, Michaud JL, Drapeau P, Lafrenière RG, Rouleau GA, Krebs MO.

Transl Psychiatry. 2011 Nov 15;1:e55. doi: 10.1038/tp.2011.52.

47.

Childhood onset schizophrenia: support for a progressive neurodevelopmental disorder.

Rapoport JL, Gogtay N.

Int J Dev Neurosci. 2011 May;29(3):251-8. doi: 10.1016/j.ijdevneu.2010.10.003. Epub 2010 Oct 16. Review.

48.

Longitudinally mapping the influence of sex and androgen signaling on the dynamics of human cortical maturation in adolescence.

Raznahan A, Lee Y, Stidd R, Long R, Greenstein D, Clasen L, Addington A, Gogtay N, Rapoport JL, Giedd JN.

Proc Natl Acad Sci U S A. 2010 Sep 28;107(39):16988-93. doi: 10.1073/pnas.1006025107. Epub 2010 Sep 14.

49.

Structural MRI of pediatric brain development: what have we learned and where are we going?

Giedd JN, Rapoport JL.

Neuron. 2010 Sep 9;67(5):728-34. doi: 10.1016/j.neuron.2010.08.040. Review.

50.

Direct measure of the de novo mutation rate in autism and schizophrenia cohorts.

Awadalla P, Gauthier J, Myers RA, Casals F, Hamdan FF, Griffing AR, Côté M, Henrion E, Spiegelman D, Tarabeux J, Piton A, Yang Y, Boyko A, Bustamante C, Xiong L, Rapoport JL, Addington AM, DeLisi JL, Krebs MO, Joober R, Millet B, Fombonne E, Mottron L, Zilversmit M, Keebler J, Daoud H, Marineau C, Roy-Gagnon MH, Dubé MP, Eyre-Walker A, Drapeau P, Stone EA, Lafrenière RG, Rouleau GA.

Am J Hum Genet. 2010 Sep 10;87(3):316-24. doi: 10.1016/j.ajhg.2010.07.019.

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