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Serum bicarbonate and cardiovascular events in hypertensive adults: results from the Systolic Blood Pressure Intervention Trial.

Dobre M, Pajewski NM, Beddhu S, Chonchol M, Hostetter TH, Li P, Rahman M, Servilla K, Weiner DE, Wright JT, Raphael KL; SPRINT Research Group.

Nephrol Dial Transplant. 2019 Aug 14. pii: gfz149. doi: 10.1093/ndt/gfz149. [Epub ahead of print]


Innovations in Endoscopic Therapy for Gastroesophageal Reflux Disease.

Raphael KL, Walsh P, Benias PC.

Gastrointest Endosc Clin N Am. 2020 Apr;30(2):291-307. doi: 10.1016/j.giec.2019.12.009. Epub 2020 Feb 13. Review.


Urine Markers of Kidney Tubule Cell Injury and Kidney Function Decline in SPRINT Trial Participants with CKD.

Malhotra R, Katz R, Jotwani V, Ambrosius WT, Raphael KL, Haley W, Rastogi A, Cheung AK, Freedman BI, Punzi H, Rocco MV, Ix JH, Shlipak MG.

Clin J Am Soc Nephrol. 2020 Mar 6;15(3):349-358. doi: 10.2215/CJN.02780319. Epub 2020 Feb 28.


Sodium Bicarbonate Supplementation and Urinary TGF-β1 in Nonacidotic Diabetic Kidney Disease: A Randomized, Controlled Trial.

Raphael KL, Greene T, Wei G, Bullshoe T, Tuttle K, Cheung AK, Beddhu S.

Clin J Am Soc Nephrol. 2020 Feb 7;15(2):200-208. doi: 10.2215/CJN.06600619. Epub 2020 Jan 23.


A Randomized Trial Comparing the Safety, Adherence, and Pharmacodynamics Profiles of Two Doses of Sodium Bicarbonate in CKD: the BASE Pilot Trial.

Raphael KL, Isakova T, Ix JH, Raj DS, Wolf M, Fried LF, Gassman JJ, Kendrick C, Larive B, Flessner MF, Mendley SR, Hostetter TH, Block GA, Li P, Middleton JP, Sprague SM, Wesson DE, Cheung AK.

J Am Soc Nephrol. 2020 Jan;31(1):161-174. doi: 10.1681/ASN.2019030287. Epub 2019 Dec 17.


Adjunctive Yield of Wide-Area Transepithelial Sampling for Dysplasia Detection After Advanced Imaging and Random Biopsies in Barrett's Esophagus.

Raphael KL, Stewart M, Sejpal DV, Cheung M, Whitson MJ, Han D, Benias PC, Lee C, Miller LS, Trindade AJ.

Clin Transl Gastroenterol. 2019 Dec;10(12):e00107. doi: 10.14309/ctg.0000000000000107.


Salvage CryoBalloon cryotherapy ablation for a duodenal adenoma.

Raphael KL, Benias PC, Trindade AJ.

Endoscopy. 2019 Dec 9. doi: 10.1055/a-1066-4518. [Epub ahead of print] No abstract available.


Volumetric laser endomicroscopy features of dysplasia at the gastric cardia in Barrett's oesophagus: results from an observational cohort study.

Trindade AJ, Raphael KL, Inamdar S, Stewart M, Berkowitz J, Vegesna A, McKinley MJ, Benias PC, Kahn A, Leggett CL, Lee C, Sejpal DV, Rishi A.

BMJ Open Gastroenterol. 2019 Oct 23;6(1):e000340. doi: 10.1136/bmjgast-2019-000340. eCollection 2019.


Digital cholangioscopy in a patient with biliary tract intraductal papillary mucinous neoplasm.

Raphael KL, Wang J, Benias PC, Vitkovski T, Grimaldi G, Trindade AJ.

VideoGIE. 2019 Aug 30;4(11):517-518. doi: 10.1016/j.vgie.2019.07.007. eCollection 2019 Nov. No abstract available.


Treatment of metabolic acidosis with sodium bicarbonate delays progression of chronic kidney disease: the UBI Study.

Di Iorio BR, Bellasi A, Raphael KL, Santoro D, Aucella F, Garofano L, Ceccarelli M, Di Lullo L, Capolongo G, Di Iorio M, Guastaferro P, Capasso G; UBI Study Group.

J Nephrol. 2019 Dec;32(6):989-1001. doi: 10.1007/s40620-019-00656-5. Epub 2019 Oct 9.


CKD in Native Hawaiians and Pacific Islanders: Trouble in Paradise.

Naʻai D, Raphael KL.

Clin J Am Soc Nephrol. 2019 Nov 7;14(11):1661-1663. doi: 10.2215/CJN.03260319. Epub 2019 Sep 9. No abstract available.


Distinct Dimensions of Kidney Health and Risk of Cardiovascular Disease, Heart Failure, and Mortality.

Lee AK, Katz R, Jotwani V, Garimella PS, Ambrosius WT, Cheung AK, Gren LH, Neyra JA, Punzi H, Raphael KL, Shlipak MG, Ix JH.

Hypertension. 2019 Oct;74(4):872-879. doi: 10.1161/HYPERTENSIONAHA.119.13339. Epub 2019 Aug 5.


Drug removal of gastric acid: a novel treatment of metabolic acidosis.

Kraut JA, Raphael KL.

Lancet. 2019 Aug 3;394(10196):363-364. doi: 10.1016/S0140-6736(19)31473-4. Epub 2019 Jun 24. No abstract available.


The Dietary Approaches to Stop Hypertension (DASH) diet in chronic kidney disease: should we embrace it?

Raphael KL.

Kidney Int. 2019 Jun;95(6):1296-1298. doi: 10.1016/j.kint.2019.01.026.


Effects of Nicotinamide and Lanthanum Carbonate on Serum Phosphate and Fibroblast Growth Factor-23 in CKD: The COMBINE Trial.

Ix JH, Isakova T, Larive B, Raphael KL, Raj DS, Cheung AK, Sprague SM, Fried LF, Gassman JJ, Middleton JP, Flessner MF, Block GA, Wolf M.

J Am Soc Nephrol. 2019 Jun;30(6):1096-1108. doi: 10.1681/ASN.2018101058. Epub 2019 May 13.


Safety and feasibility of performing peroral endoscopic myotomy as an outpatient procedure with same-day discharge.

Benias PC, Korrapati P, Raphael KL, D'Souza LS, Inamdar S, Trindade AJ, Lee C, Kumbhari V, Sejpal DV, Okolo P, Khashab MA, Miller L, Carr-Locke D.

Gastrointest Endosc. 2019 Oct;90(4):570-578. doi: 10.1016/j.gie.2019.04.247. Epub 2019 May 10.


Metabolic Acidosis in CKD: Core Curriculum 2019.

Raphael KL.

Am J Kidney Dis. 2019 Aug;74(2):263-275. doi: 10.1053/j.ajkd.2019.01.036. Epub 2019 Apr 26. Review.


Urinary Biomarkers of Tubular Damage Are Associated with Mortality but Not Cardiovascular Risk among Systolic Blood Pressure Intervention Trial Participants with Chronic Kidney Disease.

Jotwani VK, Lee AK, Estrella MM, Katz R, Garimella PS, Malhotra R, Rifkin DE, Ambrosius W, Freedman BI, Cheung AK, Raphael KL, Drawz P, Neyra JA, Oparil S, Punzi H, Shlipak MG, Ix JH; for the SPRINT Research Group.

Am J Nephrol. 2019;49(5):346-355. doi: 10.1159/000499531. Epub 2019 Apr 2.


Role of Multimodal Cardiac Imaging in Diagnosing a Primary Intimal Sarcoma of the Left Atrial Appendage.

Raphael KL, Martinez AP, Clements SD, Isiadinso I.

Tex Heart Inst J. 2019 Feb 1;46(1):28-31. doi: 10.14503/THIJ-16-5896. eCollection 2019 Feb.


PTH, FGF23, and Intensive Blood Pressure Lowering in Chronic Kidney Disease Participants in SPRINT.

Ginsberg C, Craven TE, Chonchol MB, Cheung AK, Sarnak MJ, Ambrosius WT, Killeen AA, Raphael KL, Bhatt UY, Chen J, Chertow GM, Freedman BI, Oparil S, Papademetriou V, Wall BM, Wright CB, Ix JH, Shlipak MG; SPRINT Research Group.

Clin J Am Soc Nephrol. 2018 Dec 7;13(12):1816-1824. doi: 10.2215/CJN.05390518. Epub 2018 Nov 13.


The Familiality of Rapid Renal Decline in Diabetes.

Frodsham SG, Yu Z, Lyons AM, Agarwal A, Pezzolesi MH, Dong L, Srinivas TR, Ying J, Greene T, Raphael KL, Smith KR, Pezzolesi MG.

Diabetes. 2019 Feb;68(2):420-429. doi: 10.2337/db18-0838. Epub 2018 Nov 13.


It Is Really Time for Ammonium Measurement.

Raphael KL, Yee J.

Adv Chronic Kidney Dis. 2018 Jul;25(4):297-300. doi: 10.1053/j.ackd.2018.03.003. No abstract available.


Serum Bicarbonate Concentration and Cognitive Function in Hypertensive Adults.

Dobre M, Gaussoin SA, Bates JT, Chonchol MB, Cohen DL, Hostetter TH, Raphael KL, Taylor AA, Lerner AJ, Wright JT Jr, Rahman M; SPRINT Research Group.

Clin J Am Soc Nephrol. 2018 Apr 6;13(4):596-603. doi: 10.2215/CJN.07050717. Epub 2018 Mar 22.


Correlation of Urine Ammonium and Urine Osmolal Gap in Kidney Transplant Recipients.

Raphael KL, Ix JH.

Clin J Am Soc Nephrol. 2018 Apr 6;13(4):638-640. doi: 10.2215/CJN.13311117. Epub 2018 Mar 8. No abstract available.


Relationship of acid-base status with arterial stiffness in community-living elders: the Health ABC Study.

Chen W, Newman AB, Fried LF, Rifkin DE, Shlipak MG, Sarnak MJ, Katz R, Madero M, Raphael KL, Bushinsky DA, Ix JH.

Nephrol Dial Transplant. 2018 Sep 1;33(9):1572-1579. doi: 10.1093/ndt/gfx292.


Association between Urine Ammonium and Urine TGF-β1 in CKD.

Raphael KL, Gilligan S, Hostetter TH, Greene T, Beddhu S.

Clin J Am Soc Nephrol. 2018 Feb 7;13(2):223-230. doi: 10.2215/CJN.07510717. Epub 2017 Nov 16.


Urine Anion Gap to Predict Urine Ammonium and Related Outcomes in Kidney Disease.

Raphael KL, Gilligan S, Ix JH.

Clin J Am Soc Nephrol. 2018 Feb 7;13(2):205-212. doi: 10.2215/CJN.03770417. Epub 2017 Nov 2.


Hyperkalemia and Hypokalemia in CKD: Prevalence, Risk Factors, and Clinical Outcomes.

Gilligan S, Raphael KL.

Adv Chronic Kidney Dis. 2017 Sep;24(5):315-318. doi: 10.1053/j.ackd.2017.06.004. Review.


Metabolic Acidosis and Subclinical Metabolic Acidosis in CKD.

Raphael KL.

J Am Soc Nephrol. 2018 Feb;29(2):376-382. doi: 10.1681/ASN.2017040422. Epub 2017 Oct 13. Review.


Associations of Protein-Energy Wasting Syndrome Criteria With Body Composition and Mortality in the General and Moderate Chronic Kidney Disease Populations in the United States.

Beddhu S, Chen X, Wei G, Raj D, Raphael KL, Boucher R, Chonchol MB, Murtaugh MA, Greene T.

Kidney Int Rep. 2017 May;2(3):390-399. doi: 10.1016/j.ekir.2017.01.002. Epub 2017 Jan 10.


Pancreatic Adenocarcinoma: Improving Prevention and Survivorship.

Sohal DPS, Willingham FF, Falconi M, Raphael KL, Crippa S.

Am Soc Clin Oncol Educ Book. 2017;37:301-310. doi: 10.14694/EDBK_175222. Review.


Urine Ammonium Predicts Clinical Outcomes in Hypertensive Kidney Disease.

Raphael KL, Carroll DJ, Murray J, Greene T, Beddhu S.

J Am Soc Nephrol. 2017 Aug;28(8):2483-2490. doi: 10.1681/ASN.2016101151. Epub 2017 Apr 6.


Acidosis and Kidney Allograft Survival.

Raphael KL, Shihab FS.

J Am Soc Nephrol. 2017 Jun;28(6):1672-1674. doi: 10.1681/ASN.2017020133. Epub 2017 Mar 27. No abstract available.


C3 glomerulopathy in adults: a distinct patient subset showing frequent association with monoclonal gammopathy and poor renal outcome.

Lloyd IE, Gallan A, Huston HK, Raphael KL, Miller DV, Revelo MP, Khalighi MA.

Clin Kidney J. 2016 Dec;9(6):794-799. Epub 2016 Sep 23.


Pancreatic Insufficiency Secondary to Tobacco Exposure: A Controlled Cross-Sectional Evaluation.

Raphael KL, Chawla S, Kim S, Keith CG, Propp DR, Chen ZN, Woods KE, Keilin SA, Cai Q, Willingham FF.

Pancreas. 2017 Feb;46(2):237-243. doi: 10.1097/MPA.0000000000000721.


Hereditary pancreatitis: current perspectives.

Raphael KL, Willingham FF.

Clin Exp Gastroenterol. 2016 Jul 26;9:197-207. doi: 10.2147/CEG.S84358. eCollection 2016. Review.


Approach to the Treatment of Chronic Metabolic Acidosis in CKD.

Raphael KL.

Am J Kidney Dis. 2016 Apr;67(4):696-702. doi: 10.1053/j.ajkd.2015.12.016. Epub 2016 Jan 6.


Bicarbonate Concentration, Acid-Base Status, and Mortality in the Health, Aging, and Body Composition Study.

Raphael KL, Murphy RA, Shlipak MG, Satterfield S, Huston HK, Sebastian A, Sellmeyer DE, Patel KV, Newman AB, Sarnak MJ, Ix JH, Fried LF; Health ABC Study.

Clin J Am Soc Nephrol. 2016 Feb 5;11(2):308-16. doi: 10.2215/CJN.06200615. Epub 2016 Jan 14.


A Risk Assessment of the Jaffe vs Enzymatic Method for Creatinine Measurement in an Outpatient Population.

Schmidt RL, Straseski JA, Raphael KL, Adams AH, Lehman CM.

PLoS One. 2015 Nov 24;10(11):e0143205. doi: 10.1371/journal.pone.0143205. eCollection 2015.


Hypertension and Polypharmacy in Elderly Nursing Home Residents: When Less is More.

Raphael KL, Beddhu S.

Am J Kidney Dis. 2015 Oct;66(4):561-3. doi: 10.1053/j.ajkd.2015.06.012. Epub 2015 Jul 26. No abstract available.


Levetiracetam Use With Continuous Renal Replacement Therapy.

Louie JM, Raphael KL, Barker B.

Ann Pharmacother. 2015 Sep;49(9):1079-80. doi: 10.1177/1060028015591845. Epub 2015 Jun 23. No abstract available.


Hepatitis B Virus Reactivation During Successful Treatment of Hepatitis C Virus With Sofosbuvir and Simeprevir.

Collins JM, Raphael KL, Terry C, Cartwright EJ, Pillai A, Anania FA, Farley MM.

Clin Infect Dis. 2015 Oct 15;61(8):1304-6. doi: 10.1093/cid/civ474. Epub 2015 Jun 16.


Rationale and Approaches to Phosphate and Fibroblast Growth Factor 23 Reduction in CKD.

Isakova T, Ix JH, Sprague SM, Raphael KL, Fried L, Gassman JJ, Raj D, Cheung AK, Kusek JW, Flessner MF, Wolf M, Block GA.

J Am Soc Nephrol. 2015 Oct;26(10):2328-39. doi: 10.1681/ASN.2015020117. Epub 2015 May 12. Review.


Net endogenous acid production and mortality in NHANES III.

Huston HK, Abramowitz MK, Zhang Y, Greene T, Raphael KL.

Nephrology (Carlton). 2015 Mar;20(3):209-15. doi: 10.1111/nep.12365.


Prevalence of and risk factors for reduced serum bicarbonate in chronic kidney disease.

Raphael KL, Zhang Y, Ying J, Greene T.

Nephrology (Carlton). 2014 Oct;19(10):648-54. doi: 10.1111/nep.12315.


Serum bicarbonate and mortality in adults in NHANES III.

Raphael KL, Zhang Y, Wei G, Greene T, Cheung AK, Beddhu S.

Nephrol Dial Transplant. 2013 May;28(5):1207-13. doi: 10.1093/ndt/gfs609. Epub 2013 Jan 24.


Associations of serum skeletal alkaline phosphatase with elevated C-reactive protein and mortality.

Filipowicz R, Greene T, Wei G, Cheung AK, Raphael KL, Baird BC, Beddhu S.

Clin J Am Soc Nephrol. 2013 Jan;8(1):26-32. doi: 10.2215/CJN.12031111. Epub 2012 Nov 2.


Cognitive function and the risk of death in chronic kidney disease.

Raphael KL, Wei G, Greene T, Baird BC, Beddhu S.

Am J Nephrol. 2012;35(1):49-57. doi: 10.1159/000334872. Epub 2011 Dec 21.


Implications of the Frequent Hemodialysis Network-Daily Trial.

Raphael KL, Cheung AK.

Semin Dial. 2011 Nov-Dec;24(6):621-8. doi: 10.1111/j.1525-139X.2011.00994.x. Epub 2011 Nov 18.


High dietary fiber intake is associated with decreased inflammation and all-cause mortality in patients with chronic kidney disease.

Krishnamurthy VM, Wei G, Baird BC, Murtaugh M, Chonchol MB, Raphael KL, Greene T, Beddhu S.

Kidney Int. 2012 Feb;81(3):300-6. doi: 10.1038/ki.2011.355. Epub 2011 Oct 19.

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