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Items: 1 to 50 of 119

1.

Sharpening the Scissors: Mechanistic Details of CRISPR/Cas9 Improve Functional Understanding and Inspire Future Research.

Raper AT, Stephenson AA, Suo Z.

J Am Chem Soc. 2018 Sep 12;140(36):11142-11152. doi: 10.1021/jacs.8b05469. Epub 2018 Aug 30.

PMID:
30160947
2.

Kinetic Mechanism of DNA Polymerases: Contributions of Conformational Dynamics and a Third Divalent Metal Ion.

Raper AT, Reed AJ, Suo Z.

Chem Rev. 2018 Jun 27;118(12):6000-6025. doi: 10.1021/acs.chemrev.7b00685. Epub 2018 Jun 4.

PMID:
29863852
3.

Investigation of sliding DNA clamp dynamics by single-molecule fluorescence, mass spectrometry and structure-based modeling.

Gadkari VV, Harvey SR, Raper AT, Chu WT, Wang J, Wysocki VH, Suo Z.

Nucleic Acids Res. 2018 Apr 6;46(6):3103-3118. doi: 10.1093/nar/gky125.

4.

Bidirectional Degradation of DNA Cleavage Products Catalyzed by CRISPR/Cas9.

Stephenson AA, Raper AT, Suo Z.

J Am Chem Soc. 2018 Mar 14;140(10):3743-3750. doi: 10.1021/jacs.7b13050. Epub 2018 Feb 20.

PMID:
29461055
5.

Functional Insights Revealed by the Kinetic Mechanism of CRISPR/Cas9.

Raper AT, Stephenson AA, Suo Z.

J Am Chem Soc. 2018 Feb 28;140(8):2971-2984. doi: 10.1021/jacs.7b13047. Epub 2018 Feb 19.

PMID:
29442507
6.

Csf1r-mApple Transgene Expression and Ligand Binding In Vivo Reveal Dynamics of CSF1R Expression within the Mononuclear Phagocyte System.

Hawley CA, Rojo R, Raper A, Sauter KA, Lisowski ZM, Grabert K, Bain CC, Davis GM, Louwe PA, Ostrowski MC, Hume DA, Pridans C, Jenkins SJ.

J Immunol. 2018 Mar 15;200(6):2209-2223. doi: 10.4049/jimmunol.1701488. Epub 2018 Feb 12.

7.

Macrophage colony-stimulating factor increases hepatic macrophage content, liver growth, and lipid accumulation in neonatal rats.

Pridans C, Sauter KA, Irvine KM, Davis GM, Lefevre L, Raper A, Rojo R, Nirmal AJ, Beard P, Cheeseman M, Hume DA.

Am J Physiol Gastrointest Liver Physiol. 2018 Mar 1;314(3):G388-G398. doi: 10.1152/ajpgi.00343.2017. Epub 2017 Dec 21.

8.

Structural basis for the D-stereoselectivity of human DNA polymerase β.

Vyas R, Reed AJ, Raper AT, Zahurancik WJ, Wallenmeyer PC, Suo Z.

Nucleic Acids Res. 2017 Jun 2;45(10):6228-6237. doi: 10.1093/nar/gkx252.

9.

A novel approach to measuring macrophage-specific reverse cholesterol transport in vivo in humans.

Cuchel M, Raper AC, Conlon DM, Pryma DA, Freifelder RH, Poria R, Cromley D, Li X, Dunbar RL, French B, Qu L, Farver W, Su CC, Lund-Katz S, Baer A, Ruotolo G, Akerblad P, Ryan CS, Xiao L, Kirchgessner TG, Millar JS, Billheimer JT, Rader DJ.

J Lipid Res. 2017 Apr;58(4):752-762. doi: 10.1194/jlr.M075226. Epub 2017 Feb 6.

10.

Advances in Structural and Single-Molecule Methods for Investigating DNA Lesion Bypass and Repair Polymerases.

Raper AT, Reed AJ, Gadkari VV, Suo Z.

Chem Res Toxicol. 2017 Jan 17;30(1):260-269. doi: 10.1021/acs.chemrestox.6b00342. Epub 2016 Dec 8.

PMID:
28092942
11.

Structural Insights into the Post-Chemistry Steps of Nucleotide Incorporation Catalyzed by a DNA Polymerase.

Reed AJ, Vyas R, Raper AT, Suo Z.

J Am Chem Soc. 2017 Jan 11;139(1):465-471. doi: 10.1021/jacs.6b11258. Epub 2016 Dec 27.

PMID:
27959534
12.

Investigation of Intradomain Motions of a Y-Family DNA Polymerase during Substrate Binding and Catalysis.

Raper AT, Suo Z.

Biochemistry. 2016 Oct 18;55(41):5832-5844. doi: 10.1021/acs.biochem.6b00878. Epub 2016 Oct 10.

PMID:
27685341
13.

A Csf1r-EGFP Transgene Provides a Novel Marker for Monocyte Subsets in Sheep.

Pridans C, Davis GM, Sauter KA, Lisowski ZM, Corripio-Miyar Y, Raper A, Lefevre L, Young R, McCulloch ME, Lillico S, Milne E, Whitelaw B, Hume DA.

J Immunol. 2016 Sep 15;197(6):2297-305. doi: 10.4049/jimmunol.1502336. Epub 2016 Aug 12.

14.

Single-Molecule Investigation of Response to Oxidative DNA Damage by a Y-Family DNA Polymerase.

Raper AT, Gadkari VV, Maxwell BA, Suo Z.

Biochemistry. 2016 Apr 12;55(14):2187-96. doi: 10.1021/acs.biochem.6b00166. Epub 2016 Mar 30.

15.

Long-term clinical results of microsomal triglyceride transfer protein inhibitor use in a patient with homozygous familial hypercholesterolemia.

Raper A, Kolansky DM, Sachais BS, Meagher EA, Baer AL, Cuchel M.

J Clin Lipidol. 2015 Jan-Feb;9(1):107-12. doi: 10.1016/j.jacl.2014.08.005. Epub 2014 Aug 23.

16.

A comparison of vascular inflammation in psoriasis, rheumatoid arthritis, and healthy subjects by FDG-PET/CT: a pilot study.

Rose S, Sheth NH, Baker JF, Ogdie A, Raper A, Saboury B, Werner TJ, Thomas P, Vanvoorhees A, Alavi A, Torigian DA, Gelfand JM, Mehta NN.

Am J Cardiovasc Dis. 2013 Nov 1;3(4):273-8. eCollection 2013.

17.

Aortic vascular inflammation in psoriasis is associated with HDL particle size and concentration: a pilot study.

Yu Y, Sheth N, Krishnamoorthy P, Saboury B, Raper A, Baer A, Ochotony R, Doveikis J, Derohannessian S, Voorhees AS, Torigian DA, Alavi A, Gelfand JM, Mehta NN.

Am J Cardiovasc Dis. 2012;2(4):285-92. Epub 2012 Oct 23.

18.

Abnormal lipoprotein particles and cholesterol efflux capacity in patients with psoriasis.

Mehta NN, Li R, Krishnamoorthy P, Yu Y, Farver W, Rodrigues A, Raper A, Wilcox M, Baer A, DerOhannesian S, Wolfe M, Reilly MP, Rader DJ, VanVoorhees A, Gelfand JM.

Atherosclerosis. 2012 Sep;224(1):218-21. doi: 10.1016/j.atherosclerosis.2012.06.068. Epub 2012 Jul 21.

19.

The impact of psoriasis on 10-year Framingham risk.

Mehta NN, Krishnamoorthy P, Yu Y, Khan O, Raper A, Van Voorhees A, Troxel AB, Gelfand JM.

J Am Acad Dermatol. 2012 Oct;67(4):796-8. doi: 10.1016/j.jaad.2012.05.016. Epub 2012 Jun 26. No abstract available.

20.

Treatment of familial hypercholesterolemia: is there a need beyond statin therapy?

Raper A, Kolansky DM, Cuchel M.

Curr Atheroscler Rep. 2012 Feb;14(1):11-6. doi: 10.1007/s11883-011-0215-y. Review.

PMID:
22135161
21.

Systemic and vascular inflammation in patients with moderate to severe psoriasis as measured by [18F]-fluorodeoxyglucose positron emission tomography-computed tomography (FDG-PET/CT): a pilot study.

Mehta NN, Yu Y, Saboury B, Foroughi N, Krishnamoorthy P, Raper A, Baer A, Antigua J, Van Voorhees AS, Torigian DA, Alavi A, Gelfand JM.

Arch Dermatol. 2011 Sep;147(9):1031-9. doi: 10.1001/archdermatol.2011.119. Epub 2011 May 16.

22.

Primary deficiency of microsomal triglyceride transfer protein in human abetalipoproteinemia is associated with loss of CD1 function.

Zeissig S, Dougan SK, Barral DC, Junker Y, Chen Z, Kaser A, Ho M, Mandel H, McIntyre A, Kennedy SM, Painter GF, Veerapen N, Besra GS, Cerundolo V, Yue S, Beladi S, Behar SM, Chen X, Gumperz JE, Breckpot K, Raper A, Baer A, Exley MA, Hegele RA, Cuchel M, Rader DJ, Davidson NO, Blumberg RS.

J Clin Invest. 2010 Aug;120(8):2889-99. doi: 10.1172/JCI42703. Epub 2010 Jul 1.

23.

Individual plasmacytoid dendritic cells are major contributors to the production of multiple innate cytokines in an organ-specific manner during viral infection.

Zucchini N, Bessou G, Robbins SH, Chasson L, Raper A, Crocker PR, Dalod M.

Int Immunol. 2008 Jan;20(1):45-56. Epub 2007 Nov 13.

PMID:
18000008
24.

Negative regulation of leucocyte functions by CD33-related siglecs.

Avril T, Attrill H, Zhang J, Raper A, Crocker PR.

Biochem Soc Trans. 2006 Dec;34(Pt 6):1024-7.

PMID:
17073742
25.

Characterization of Siglec-H as a novel endocytic receptor expressed on murine plasmacytoid dendritic cell precursors.

Zhang J, Raper A, Sugita N, Hingorani R, Salio M, Palmowski MJ, Cerundolo V, Crocker PR.

Blood. 2006 May 1;107(9):3600-8. Epub 2006 Jan 5.

26.

The syndrome of sudden severe painless myocardial ischemia.

Raper AJ, Hastillo A, Paulsen WJ.

Am Heart J. 1984 Apr;107(4):813-5. No abstract available.

PMID:
6702585
27.

Results of medical versus surgical treatment of unstable angina pectoris.

Raper AJ, Vetrovec GW.

Am J Cardiol. 1983 Mar 1;51(5):918. No abstract available.

PMID:
6829461
28.

Grand rounds: non-infectious thrombotic endocarditis.

Schmidt SB, Raper AJ.

Va Med. 1982 Aug;109(8):522-4, 526. No abstract available.

PMID:
7136234
29.

Cars: personal and national catastrophe.

Raper AJ.

Ann Intern Med. 1980 Jan;92(1):125. No abstract available.

PMID:
7350858
30.

University students with special needs speak out: improving the quality of educational experiences.

Turnbull AP, Raper A, Mesibov GB.

Rehabil Lit. 1978 Oct;39(10):294-8. No abstract available.

PMID:
151901
31.

Therapy for systolic hypertension.

Raper AJ.

Ann Intern Med. 1978 Sep;89(3):425-6. No abstract available.

PMID:
686562
32.

Role of tissue hypoxia in local regulation of cerebral microcirculation.

Kontos HA, Wei EP, Raper AJ, Rosenblum WI, Navari RM, Patterson JL Jr.

Am J Physiol. 1978 May;234(5):H582-91.

PMID:
645924
33.

Bethanidine vs Guanethidine.

Raper AJ, Richardson DW.

Circulation. 1978 Apr;57(4):841-3. No abstract available.

PMID:
343946
34.

Management of complicated hypertension including hypertensive emergencies.

Richardson DW, Raper AJ.

Cardiovasc Clin. 1978;9(1):227-41. No abstract available.

PMID:
667883
35.

Pheochromocytoma of the urinary bladder: a broad clinical spectrum.

Raper AJ, Jessee EF, Texter JH Jr, Giffler RF, Hietala TS.

Am J Cardiol. 1977 Nov;40(5):820-4.

PMID:
920620
36.

Paraganglioma of urinary bladder wall.

Texter JH Jr, Crane DB, Hietala SO, Raper AJ.

Urology. 1977 Jul;10(1):79-82.

PMID:
878132
37.

Analysis of vasoactivity of local pH, PCO2 and bicarbonate on pial vessels.

Kontos HA, Raper AJ, Patterson JL.

Stroke. 1977 May-Jun;8(3):358-60.

PMID:
16363
38.

Local mechanism of CO2 action of cat pial arterioles.

Kontos HA, Wei EP, Raper AJ, Patterson JL Jr.

Stroke. 1977 Mar-Apr;8(2):226-9.

PMID:
15334
39.

Role of local tissue hypoxia in the vasodilation of hypotension and arterial hypoxemia.

Kontos HA, Wei EP, Raper AJ, Rosenblum WI, Patterson JL Jr.

Acta Neurol Scand Suppl. 1977;64:210-1. No abstract available.

PMID:
268788
40.

Hypertension screening among dental patients.

Abbey LM, Keener LH, Raper AJ.

J Am Dent Assoc. 1976 Nov;93(5):996-1000.

PMID:
1067360
41.

A dental school hypertension screening program.

Abbey LM, Keener LH, Raper AJ.

J Dent Educ. 1976 May;40(5):287-9.

PMID:
1063175
42.

The status of high blood pressure education among Virginia dentists and dental auxillaries.

Abbey LM, Keener LH, Raper AJ.

Va Dent J. 1976 Feb;53(1):13-9. No abstract available.

PMID:
1075784
43.

Determinants of response of pial arteries to norepinephrine and sympathetic nerve stimulation.

Wei EP, Raper AJ, Kontos HA, Patterson JL Jr.

Stroke. 1975 Nov-Dec;6(6):654-8.

PMID:
1198630
44.

Detailed description of a cranial window technique for acute and chronic experiments.

Levasseur JE, Wei EP, Raper AJ, Kontos AA, Patterson JL.

Stroke. 1975 May-Jun;6(3):308-17.

PMID:
1154467
45.

Practical office management of chronic hypertension.

Raper AJ.

Va Med Mon (1918). 1974 Nov;101(11):945-7. No abstract available.

PMID:
4428883
46.

What is a good hypertensive workup? Who needs it?

Raper AJ.

Va Med Mon (1918). 1974 Nov;101(11):942-5. No abstract available.

PMID:
4428882
47.

Letter: Wastefulness of beef-rich diet.

Raper AJ.

Ann Intern Med. 1974 Jul;81(1):124. No abstract available.

PMID:
4858138
48.

Differentiation of iron-deficiency anaemia from thalassaemia trait.

Raper AB.

Lancet. 1973 Apr 7;1(7806):778. No abstract available.

PMID:
4120762
49.

Mechanisms of action of hypocapnic alkalosis on limb blood vessels in man and dog.

Kontos HA, Richardson DW, Raper AJ, Zubair-ul-Hassan, Patterson JL Jr.

Am J Physiol. 1972 Dec;223(6):1296-307. No abstract available.

PMID:
4123706
50.

Systemic circulatory responses to hypocapnia in man.

Richardson DW, Kontos HA, Raper AJ, Patterson JL Jr.

Am J Physiol. 1972 Dec;223(6):1308-12. No abstract available.

PMID:
4118398

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