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Items: 33

1.

Preperitoneal Fat Grafting Inhibits the Formation of Intra-abdominal Adhesions in Mice.

Laukka M, Hoppela E, Salo J, Rantakari P, Gronroos TJ, Orte K, Auvinen K, Salmi M, Gerke H, Thol K, Peuhu E, Kauhanen S, Merilahti P, Hartiala P.

J Gastrointest Surg. 2019 Dec 10. doi: 10.1007/s11605-019-04425-4. [Epub ahead of print]

PMID:
31823326
2.

Fenestral diaphragms and PLVAP associations in liver sinusoidal endothelial cells are developmentally regulated.

Auvinen K, Lokka E, Mokkala E, Jäppinen N, Tyystjärvi S, Saine H, Peurla M, Shetty S, Elima K, Rantakari P, Salmi M.

Sci Rep. 2019 Oct 30;9(1):15698. doi: 10.1038/s41598-019-52068-x.

3.

Transcytosis route mediates rapid delivery of intact antibodies to draining lymph nodes.

Kähäri L, Fair-Mäkelä R, Auvinen K, Rantakari P, Jalkanen S, Ivaska J, Salmi M.

J Clin Invest. 2019 Jun 24;129(8):3086-3102. doi: 10.1172/JCI125740. eCollection 2019 Jun 24.

4.

Clever-1 contributes to lymphocyte entry into the spleen via the red pulp.

Tadayon S, Dunkel J, Takeda A, Halle O, Karikoski M, Gerke H, Rantakari P, Virtakoivu R, Pabst O, Salmi M, Hollmén M, Jalkanen S.

Sci Immunol. 2019 Mar 29;4(33). pii: eaat0297. doi: 10.1126/sciimmunol.aat0297.

PMID:
30926591
5.

Fetal-derived macrophages dominate in adult mammary glands.

Jäppinen N, Félix I, Lokka E, Tyystjärvi S, Pynttäri A, Lahtela T, Gerke H, Elima K, Rantakari P, Salmi M.

Nat Commun. 2019 Jan 17;10(1):281. doi: 10.1038/s41467-018-08065-1.

6.

Enhanced Antibody Production in Clever-1/Stabilin-1-Deficient Mice.

Dunkel J, Viitala M, Karikoski M, Rantakari P, Virtakoivu R, Elima K, Hollmén M, Jalkanen S, Salmi M.

Front Immunol. 2018 Oct 8;9:2257. doi: 10.3389/fimmu.2018.02257. eCollection 2018.

7.

Amine oxidase activity regulates the development of pulmonary fibrosis.

Marttila-Ichihara F, Elima K, Auvinen K, Veres TZ, Rantakari P, Weston C, Miyasaka M, Adams D, Jalkanen S, Salmi M.

FASEB J. 2017 Jun;31(6):2477-2491. doi: 10.1096/fj.201600935R. Epub 2017 Mar 1.

PMID:
28251930
8.

SHARPIN regulates collagen architecture and ductal outgrowth in the developing mouse mammary gland.

Peuhu E, Kaukonen R, Lerche M, Saari M, Guzmán C, Rantakari P, De Franceschi N, Wärri A, Georgiadou M, Jacquemet G, Mattila E, Virtakoivu R, Liu Y, Attieh Y, Silva KA, Betz T, Sundberg JP, Salmi M, Deugnier MA, Eliceiri KW, Ivaska J.

EMBO J. 2017 Jan 17;36(2):165-182. doi: 10.15252/embj.201694387. Epub 2016 Dec 14.

9.

Allergen-Induced CD4+ T Cell Cytokine Production within Airway Mucosal Dendritic Cell-T Cell Clusters Drives the Local Recruitment of Myeloid Effector Cells.

Veres TZ, Kopcsányi T, van Panhuys N, Gerner MY, Liu Z, Rantakari P, Dunkel J, Miyasaka M, Salmi M, Jalkanen S, Germain RN.

J Immunol. 2017 Jan 15;198(2):895-907. doi: 10.4049/jimmunol.1601448. Epub 2016 Nov 30.

10.

Thymocytes in Lyve1-CRE/S1pr1f/f Mice Accumulate in the Thymus due to Cell-Intrinsic Loss of Sphingosine-1-Phosphate Receptor Expression.

Takeda A, Hossain MS, Rantakari P, Simmons S, Sasaki N, Salmi M, Jalkanen S, Miyasaka M.

Front Immunol. 2016 Nov 8;7:489. eCollection 2016.

11.

Fetal liver endothelium regulates the seeding of tissue-resident macrophages.

Rantakari P, Jäppinen N, Lokka E, Mokkala E, Gerke H, Peuhu E, Ivaska J, Elima K, Auvinen K, Salmi M.

Nature. 2016 Oct 20;538(7625):392-396. doi: 10.1038/nature19814. Epub 2016 Oct 12.

PMID:
27732581
12.

Gene-expression profiling of different arms of lymphatic vasculature identifies candidates for manipulation of cell traffic.

Iftakhar-E-Khuda I, Fair-Mäkelä R, Kukkonen-Macchi A, Elima K, Karikoski M, Rantakari P, Miyasaka M, Salmi M, Jalkanen S.

Proc Natl Acad Sci U S A. 2016 Sep 20;113(38):10643-8. doi: 10.1073/pnas.1602357113. Epub 2016 Sep 6.

13.

Stabilin-1 expression defines a subset of macrophages that mediate tissue homeostasis and prevent fibrosis in chronic liver injury.

Rantakari P, Patten DA, Valtonen J, Karikoski M, Gerke H, Dawes H, Laurila J, Ohlmeier S, Elima K, Hübscher SG, Weston CJ, Jalkanen S, Adams DH, Salmi M, Shetty S.

Proc Natl Acad Sci U S A. 2016 Aug 16;113(33):9298-303. doi: 10.1073/pnas.1604780113. Epub 2016 Jul 29.

14.

Gremlin-1 Overexpression in Mouse Lung Reduces Silica-Induced Lymphocyte Recruitment - A Link to Idiopathic Pulmonary Fibrosis through Negative Correlation with CXCL10 Chemokine.

Koli K, Sutinen E, Rönty M, Rantakari P, Fortino V, Pulkkinen V, Greco D, Sipilä P, Myllärniemi M.

PLoS One. 2016 Jul 18;11(7):e0159010. doi: 10.1371/journal.pone.0159010. eCollection 2016.

15.

Stress-activated miR-21/miR-21* in hepatocytes promotes lipid and glucose metabolic disorders associated with high-fat diet consumption.

Calo N, Ramadori P, Sobolewski C, Romero Y, Maeder C, Fournier M, Rantakari P, Zhang FP, Poutanen M, Dufour JF, Humar B, Nef S, Foti M.

Gut. 2016 Nov;65(11):1871-1881. doi: 10.1136/gutjnl-2015-310822. Epub 2016 May 24.

16.

Fam3c modulates osteogenic cell differentiation and affects bone volume and cortical bone mineral density.

Määttä JA, Bendre A, Laanti M, Büki KG, Rantakari P, Tervola P, Saarimäki J, Poutanen M, Härkönen P, Väänänen K.

Bonekey Rep. 2016 Apr 6;5:787. doi: 10.1038/bonekey.2016.14. eCollection 2016.

17.

Direct Comparison of a Natural Loss-Of-Function Single Nucleotide Polymorphism with a Targeted Deletion in the Ncf1 Gene Reveals Different Phenotypes.

Sareila O, Hagert C, Rantakari P, Poutanen M, Holmdahl R.

PLoS One. 2015 Nov 3;10(11):e0141974. doi: 10.1371/journal.pone.0141974. eCollection 2015.

18.

Autocrine Action of IGF2 Regulates Adult β-Cell Mass and Function.

Modi H, Jacovetti C, Tarussio D, Metref S, Madsen OD, Zhang FP, Rantakari P, Poutanen M, Nef S, Gorman T, Regazzi R, Thorens B.

Diabetes. 2015 Dec;64(12):4148-57. doi: 10.2337/db14-1735. Epub 2015 Sep 17.

19.

Erratum: The endothelial protein PLVAP in lymphatics controls the entry of lymphocytes and antigens into lymph nodes.

Rantakari P, Auvinen K, Jäppinen N, Kapraali M, Valtonen J, Karikoski M, Gerke H, Iftakhar-E-Khuda I, Keuschnigg J, Umemoto E, Tohya K, Miyasaka M, Elima K, Jalkanen S, Salmi M.

Nat Immunol. 2015 May;16(5):544. doi: 10.1038/ni0515-544c. No abstract available.

PMID:
25898202
20.

The endothelial protein PLVAP in lymphatics controls the entry of lymphocytes and antigens into lymph nodes.

Rantakari P, Auvinen K, Jäppinen N, Kapraali M, Valtonen J, Karikoski M, Gerke H, Iftakhar-E-Khuda I, Keuschnigg J, Umemoto E, Tohya K, Miyasaka M, Elima K, Jalkanen S, Salmi M.

Nat Immunol. 2015 Apr;16(4):386-96. doi: 10.1038/ni.3101. Epub 2015 Feb 9. Erratum in: Nat Immunol. 2015 May;16(5):544.

PMID:
25665101
21.

Vascular adhesion protein-1 promotes liver inflammation and drives hepatic fibrosis.

Weston CJ, Shepherd EL, Claridge LC, Rantakari P, Curbishley SM, Tomlinson JW, Hubscher SG, Reynolds GM, Aalto K, Anstee QM, Jalkanen S, Salmi M, Smith DJ, Day CP, Adams DH.

J Clin Invest. 2015 Feb;125(2):501-20. doi: 10.1172/JCI73722. Epub 2014 Dec 22.

22.

Ecto-5'-nucleotidase/CD73 enhances endothelial barrier function and sprouting in blood but not lymphatic vasculature.

Yegutkin GG, Auvinen K, Rantakari P, Hollmén M, Karikoski M, Grénman R, Elima K, Jalkanen S, Salmi M.

Eur J Immunol. 2015 Feb;45(2):562-73. doi: 10.1002/eji.201444856. Epub 2014 Dec 15.

23.

Clever-1/stabilin-1 controls cancer growth and metastasis.

Karikoski M, Marttila-Ichihara F, Elima K, Rantakari P, Hollmén M, Kelkka T, Gerke H, Huovinen V, Irjala H, Holmdahl R, Salmi M, Jalkanen S.

Clin Cancer Res. 2014 Dec 15;20(24):6452-64. doi: 10.1158/1078-0432.CCR-14-1236. Epub 2014 Oct 15.

24.

Consequences of the lack of CD73 and prostatic acid phosphatase in the lymphoid organs.

Yegutkin GG, Auvinen K, Karikoski M, Rantakari P, Gerke H, Elima K, Maksimow M, Quintero IB, Vihko P, Salmi M, Jalkanen S.

Mediators Inflamm. 2014;2014:485743. doi: 10.1155/2014/485743. Epub 2014 Aug 24.

25.

SHARPIN regulates uropod detachment in migrating lymphocytes.

Pouwels J, De Franceschi N, Rantakari P, Auvinen K, Karikoski M, Mattila E, Potter C, Sundberg JP, Hogg N, Gahmberg CG, Salmi M, Ivaska J.

Cell Rep. 2013 Nov 14;5(3):619-28. doi: 10.1016/j.celrep.2013.10.011. Epub 2013 Nov 7.

26.

CD44 binds to macrophage mannose receptor on lymphatic endothelium and supports lymphocyte migration via afferent lymphatics.

Salmi M, Karikoski M, Elima K, Rantakari P, Jalkanen S.

Circ Res. 2013 Jun 7;112(12):1577-82. doi: 10.1161/CIRCRESAHA.111.300476. Epub 2013 Apr 19.

PMID:
23603511
27.

Seminal vesicles and urinary bladder as sites of aromatization of androgens in men, evidenced by a CYP19A1-driven luciferase reporter mouse and human tissue specimens.

Strauss L, Rantakari P, Sjögren K, Salminen A, Lauren E, Kallio J, Damdimopoulou P, Boström M, Boström PJ, Pakarinen P, Zhang F, Kujala P, Ohlsson C, Mäkelä S, Poutanen M.

FASEB J. 2013 Apr;27(4):1342-50. doi: 10.1096/fj.12-219048. Epub 2012 Dec 13.

PMID:
23239821
28.

Inactivation of Palb2 gene leads to mesoderm differentiation defect and early embryonic lethality in mice.

Rantakari P, Nikkilä J, Jokela H, Ola R, Pylkäs K, Lagerbohm H, Sainio K, Poutanen M, Winqvist R.

Hum Mol Genet. 2010 Aug 1;19(15):3021-9. doi: 10.1093/hmg/ddq207. Epub 2010 May 18.

PMID:
20484223
29.

Hydroxysteroid (17beta) dehydrogenase 7 activity is essential for fetal de novo cholesterol synthesis and for neuroectodermal survival and cardiovascular differentiation in early mouse embryos.

Jokela H, Rantakari P, Lamminen T, Strauss L, Ola R, Mutka AL, Gylling H, Miettinen T, Pakarinen P, Sainio K, Poutanen M.

Endocrinology. 2010 Apr;151(4):1884-92. doi: 10.1210/en.2009-0928. Epub 2010 Feb 25.

PMID:
20185768
30.

Hydroxysteroid (17{beta}) dehydrogenase 12 is essential for mouse organogenesis and embryonic survival.

Rantakari P, Lagerbohm H, Kaimainen M, Suomela JP, Strauss L, Sainio K, Pakarinen P, Poutanen M.

Endocrinology. 2010 Apr;151(4):1893-901. doi: 10.1210/en.2009-0929. Epub 2010 Feb 3.

PMID:
20130115
31.

Epithelial cells are the major site of hydroxysteroid (17beta) dehydrogenase 2 and androgen receptor expression in fetal mouse lungs during the period overlapping the surge of surfactant.

Plante J, Simard M, Rantakari P, Côté M, Provost PR, Poutanen M, Tremblay Y.

J Steroid Biochem Mol Biol. 2009 Nov;117(4-5):139-45. doi: 10.1016/j.jsbmb.2009.08.006. Epub 2009 Sep 6.

PMID:
19737616
32.

Placenta defects and embryonic lethality resulting from disruption of mouse hydroxysteroid (17-beta) dehydrogenase 2 gene.

Rantakari P, Strauss L, Kiviranta R, Lagerbohm H, Paviala J, Holopainen I, Vainio S, Pakarinen P, Poutanen M.

Mol Endocrinol. 2008 Mar;22(3):665-75. Epub 2007 Nov 29.

33.

Transgenic male mice expressing human hydroxysteroid dehydrogenase 2 indicate a role for the enzyme independent of its action on sex steroids.

Zhongyi S, Rantakari P, Lamminen T, Toppari J, Poutanen M.

Endocrinology. 2007 Aug;148(8):3827-36. Epub 2007 May 17.

PMID:
17510238

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