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Items: 1 to 50 of 89

1.

The tryptophan derivative 6-formylindolo[3,2-b]carbazole, FICZ, a dynamic mediator of endogenous aryl hydrocarbon receptor signaling, balances cell growth and differentiation.

Rannug A, Rannug U.

Crit Rev Toxicol. 2018 Aug;48(7):555-574. doi: 10.1080/10408444.2018.1493086. Epub 2018 Sep 18. Review.

PMID:
30226107
2.

Chemistry and Properties of Indolocarbazoles.

Janosik T, Rannug A, Rannug U, Wahlström N, Slätt J, Bergman J.

Chem Rev. 2018 Sep 26;118(18):9058-9128. doi: 10.1021/acs.chemrev.8b00186. Epub 2018 Sep 7.

PMID:
30191712
3.

Chromatin remodeling by curcumin alters endogenous aryl hydrocarbon receptor signaling.

Mohammadi-Bardbori A, Akbarizadeh AR, Delju F, Rannug A.

Chem Biol Interact. 2016 May 25;252:19-27. doi: 10.1016/j.cbi.2016.03.037. Epub 2016 Apr 1.

PMID:
27041069
4.

Evidence for New Light-Independent Pathways for Generation of the Endogenous Aryl Hydrocarbon Receptor Agonist FICZ.

Smirnova A, Wincent E, Vikström Bergander L, Alsberg T, Bergman J, Rannug A, Rannug U.

Chem Res Toxicol. 2016 Jan 19;29(1):75-86. doi: 10.1021/acs.chemrestox.5b00416. Epub 2015 Dec 30.

5.

NADPH Oxidase-Dependent Mechanism Explains How Arsenic and Other Oxidants Can Activate Aryl Hydrocarbon Receptor Signaling.

Mohammadi-Bardbori A, Vikström Bergander L, Rannug U, Rannug A.

Chem Res Toxicol. 2015 Dec 21;28(12):2278-86. doi: 10.1021/acs.chemrestox.5b00415. Epub 2015 Nov 16.

PMID:
26535918
6.

The aryl hydrocarbon receptor in barrier organ physiology, immunology, and toxicology.

Esser C, Rannug A.

Pharmacol Rev. 2015;67(2):259-79. doi: 10.1124/pr.114.009001. Review.

PMID:
25657351
7.

Arsenic, cadmium, mercury and nickel stimulate cell growth via NADPH oxidase activation.

Mohammadi-Bardbori A, Rannug A.

Chem Biol Interact. 2014 Dec 5;224:183-8. doi: 10.1016/j.cbi.2014.10.034. Epub 2014 Nov 10.

PMID:
25446860
8.

Quercetin, resveratrol, and curcumin are indirect activators of the aryl hydrocarbon receptor (AHR).

Mohammadi-Bardbori A, Bengtsson J, Rannug U, Rannug A, Wincent E.

Chem Res Toxicol. 2012 Sep 17;25(9):1878-84. doi: 10.1021/tx300169e. Epub 2012 Aug 28.

PMID:
22867086
9.

Inhibition of cytochrome P4501-dependent clearance of the endogenous agonist FICZ as a mechanism for activation of the aryl hydrocarbon receptor.

Wincent E, Bengtsson J, Mohammadi Bardbori A, Alsberg T, Luecke S, Rannug U, Rannug A.

Proc Natl Acad Sci U S A. 2012 Mar 20;109(12):4479-84. doi: 10.1073/pnas.1118467109. Epub 2012 Mar 5.

10.

The aryl hydrocarbon receptor (AHR), a novel regulator of human melanogenesis.

Luecke S, Backlund M, Jux B, Esser C, Krutmann J, Rannug A.

Pigment Cell Melanoma Res. 2010 Dec;23(6):828-33. doi: 10.1111/j.1755-148X.2010.00762.x.

PMID:
20973933
11.

The tryptophan photoproduct 6-formylindolo[3,2-b]carbazole helps genes jump.

Rannug A.

Proc Natl Acad Sci U S A. 2010 Oct 26;107(43):18239-40. doi: 10.1073/pnas.1013653107. Epub 2010 Oct 13. No abstract available.

12.

The aryl hydrocarbon receptor mediates UVB radiation-induced skin tanning.

Jux B, Kadow S, Luecke S, Rannug A, Krutmann J, Esser C.

J Invest Dermatol. 2011 Jan;131(1):203-10. doi: 10.1038/jid.2010.269. Epub 2010 Sep 23.

13.

Cytochrome P450 1A1 gene regulation by UVB involves crosstalk between the aryl hydrocarbon receptor and nuclear factor kappaB.

Luecke S, Wincent E, Backlund M, Rannug U, Rannug A.

Chem Biol Interact. 2010 Mar 30;184(3):466-73. doi: 10.1016/j.cbi.2010.01.038. Epub 2010 Feb 1.

PMID:
20132803
14.

The GSTP1 Ile105 Val polymorphism modifies the metabolism of toluene di-isocyanate.

Broberg KE, Warholm M, Tinnerberg H, Axmon A, Jönsson BA, Sennbro CJ, Littorin M, Rannug A.

Pharmacogenet Genomics. 2010 Feb;20(2):104-11. doi: 10.1097/FPC.0b013e328334fb84.

PMID:
20032816
15.

The aryl hydrocarbon receptor in immunity.

Esser C, Rannug A, Stockinger B.

Trends Immunol. 2009 Sep;30(9):447-54. doi: 10.1016/j.it.2009.06.005. Epub 2009 Aug 21. Review.

PMID:
19699679
16.

Short-term exposure to dioxin impairs bone tissue in male rats.

Lind PM, Wejheden C, Lundberg R, Alvarez-Lloret P, Hermsen SAB, Rodriguez-Navarro AB, Larsson S, Rannug A.

Chemosphere. 2009 May;75(5):680-684. doi: 10.1016/j.chemosphere.2008.12.024. Epub 2009 Jan 18.

PMID:
19152955
17.

The suggested physiologic aryl hydrocarbon receptor activator and cytochrome P4501 substrate 6-formylindolo[3,2-b]carbazole is present in humans.

Wincent E, Amini N, Luecke S, Glatt H, Bergman J, Crescenzi C, Rannug A, Rannug U.

J Biol Chem. 2009 Jan 30;284(5):2690-6. doi: 10.1074/jbc.M808321200. Epub 2008 Dec 2.

18.

Influence of genetic factors on toluene diisocyanate-related symptoms: evidence from a cross-sectional study.

Broberg K, Tinnerberg H, Axmon A, Warholm M, Rannug A, Littorin M.

Environ Health. 2008 Apr 30;7:15. doi: 10.1186/1476-069X-7-15.

19.

Lightening up the UV response by identification of the arylhydrocarbon receptor as a cytoplasmatic target for ultraviolet B radiation.

Fritsche E, Schäfer C, Calles C, Bernsmann T, Bernshausen T, Wurm M, Hübenthal U, Cline JE, Hajimiragha H, Schroeder P, Klotz LO, Rannug A, Fürst P, Hanenberg H, Abel J, Krutmann J.

Proc Natl Acad Sci U S A. 2007 May 22;104(21):8851-6. Epub 2007 May 14.

20.

An international case-control study of glutathione transferase and functionally related polymorphisms and risk of primary adult brain tumors.

Schwartzbaum JA, Ahlbom A, Lönn S, Warholm M, Rannug A, Auvinen A, Christensen HC, Henriksson R, Johansen C, Lindholm C, Malmer B, Salminen T, Schoemaker MJ, Swerdlow AJ, Feychting M.

Cancer Epidemiol Biomarkers Prev. 2007 Mar;16(3):559-65.

21.

Evidence of gene gene interactions in lung carcinogenesis in a large pooled analysis.

Vineis P, Anttila S, Benhamou S, Spinola M, Hirvonen A, Kiyohara C, Garte SJ, Puntoni R, Rannug A, Strange RC, Taioli E.

Carcinogenesis. 2007 Sep;28(9):1902-5. Epub 2007 Feb 16. Review.

PMID:
17307802
22.

Identification of amino acid residues in the Ah receptor involved in ligand binding.

Goryo K, Suzuki A, Del Carpio CA, Siizaki K, Kuriyama E, Mikami Y, Kinoshita K, Yasumoto K, Rannug A, Miyamoto A, Fujii-Kuriyama Y, Sogawa K.

Biochem Biophys Res Commun. 2007 Mar 9;354(2):396-402. Epub 2007 Jan 10.

PMID:
17227672
23.

Meta- and pooled analysis of GSTT1 and lung cancer: a HuGE-GSEC review.

Raimondi S, Paracchini V, Autrup H, Barros-Dios JM, Benhamou S, Boffetta P, Cote ML, Dialyna IA, Dolzan V, Filiberti R, Garte S, Hirvonen A, Husgafvel-Pursiainen K, Imyanitov EN, Kalina I, Kang D, Kiyohara C, Kohno T, Kremers P, Lan Q, London S, Povey AC, Rannug A, Reszka E, Risch A, Romkes M, Schneider J, Seow A, Shields PG, Sobti RC, Sørensen M, Spinola M, Spitz MR, Strange RC, Stücker I, Sugimura H, To-Figueras J, Tokudome S, Yang P, Yuan JM, Warholm M, Taioli E.

Am J Epidemiol. 2006 Dec 1;164(11):1027-42. Epub 2006 Sep 25.

PMID:
17000715
24.

The aryl hydrocarbon receptor and light.

Rannug A, Fritsche E.

Biol Chem. 2006 Sep;387(9):1149-57. Review.

PMID:
16972782
25.

In vitro studies of the influence of certain enzymes on the detoxification of acrylamide and glycidamide in blood.

Paulsson B, Warholm M, Rannug A, Törnqvist M.

Adv Exp Med Biol. 2005;561:127-33.

PMID:
16438295
26.

Metabolic gene polymorphisms and lung cancer risk in non-smokers. An update of the GSEC study.

Raimondi S, Boffetta P, Anttila S, Bröckmoller J, Butkiewicz D, Cascorbi I, Clapper ML, Dragani TA, Garte S, Gsur A, Haidinger G, Hirvonen A, Ingelman-Sundberg M, Kalina I, Lan Q, Leoni VP, Le Marchand L, London SJ, Neri M, Povey AC, Rannug A, Reszka E, Ryberg D, Risch A, Romkes M, Ruano-Ravina A, Schoket B, Spinola M, Sugimura H, Wu X, Taioli E.

Mutat Res. 2005 Dec 30;592(1-2):45-57. Epub 2005 Jul 11.

PMID:
16009381
27.
28.

CYP1A1, GSTM1 and GSTT1 polymorphisms and lung cancer: a pooled analysis of gene-gene interactions.

Vineis P, Veglia F, Anttila S, Benhamou S, Clapper ML, Dolzan V, Ryberg D, Hirvonen A, Kremers P, Le Marchand L, Pastorelli R, Rannug A, Romkes M, Schoket B, Strange RC, Garte S, Taioli E.

Biomarkers. 2004 May-Jun;9(3):298-305.

PMID:
15764294
29.

In vitro studies of the influence of glutathione transferases and epoxide hydrolase on the detoxification of acrylamide and glycidamide in blood.

Paulsson B, Rannug A, Henderson AP, Golding BT, Törnqvist M, Warholm M.

Mutat Res. 2005 Feb 7;580(1-2):53-9.

PMID:
15668107
30.

Metabolic fate of the Ah receptor ligand 6-formylindolo[3,2-b]carbazole.

Bergander L, Wincent E, Rannug A, Foroozesh M, Alworth W, Rannug U.

Chem Biol Interact. 2004 Oct 15;149(2-3):151-64.

PMID:
15501436
31.

Influence of CYP1A1, GSTM1, GSTT1, and NQO1 genotypes and cumulative smoking dose on lung cancer risk in a Swedish population.

Alexandrie AK, Nyberg F, Warholm M, Rannug A.

Cancer Epidemiol Biomarkers Prev. 2004 Jun;13(6):908-14.

32.

Expression of hypothalamic neuropeptides after acute TCDD treatment and distribution of Ah receptor repressor.

Fetissov SO, Huang P, Zhang Q, Mimura J, Fujii-Kuriyama Y, Rannug A, Hökfelt T, Ceccatelli S.

Regul Pept. 2004 Jun 15;119(1-2):113-24.

PMID:
15093705
33.

Association of metabolic gene polymorphisms with tobacco consumption in healthy controls.

Smits KM, Benhamou S, Garte S, Weijenberg MP, Alamanos Y, Ambrosone C, Autrup H, Autrup JL, Baranova H, Bathum L, Boffetta P, Bouchardy C, Brockmoller J, Butkiewicz D, Cascorbi I, Clapper ML, Coutelle C, Daly AK, Muzi G, Dolzan V, Duzhak TG, Farker K, Golka K, Haugen A, Hein DW, Hildesheim A, Hirvonen A, Hsieh LL, Ingelman-Sundberg M, Kalina I, Kang D, Katoh T, Kihara M, Ono-Kihara M, Kim H, Kiyohara C, Kremers P, Lazarus P, Le Marchand L, Lechner MC, London S, Manni JJ, Maugard CM, Morgan GJ, Morita S, Nazar-Stewart V, Kristensen VN, Oda Y, Parl FF, Peters WH, Rannug A, Rebbeck T, Pinto LF, Risch A, Romkes M, Salagovic J, Schoket B, Seidegard J, Shields PG, Sim E, Sinnett D, Strange RC, Stucker I, Sugimura H, To-Figueras J, Vineis P, Yu MC, Zheng W, Pedotti P, Taioli E.

Int J Cancer. 2004 Jun 10;110(2):266-70.

34.

TCDD-induced expression of Ah receptor responsive genes in the pituitary and brain of cellular retinol-binding protein (CRBP-I) knockout mice.

Huang P, Ceccatelli S, Hoegberg P, Sten Shi TJ, Håkansson H, Rannug A.

Toxicol Appl Pharmacol. 2003 Nov 1;192(3):262-74.

PMID:
14575644
35.
36.

Pooled analysis of the CYP1A1 exon 7 polymorphism and lung cancer (United States).

Le Marchand L, Guo C, Benhamou S, Bouchardy C, Cascorbi I, Clapper ML, Garte S, Haugen A, Ingelman-Sundberg M, Kihara M, Rannug A, Ryberg D, Stücker I, Sugimura H, Taioli E.

Cancer Causes Control. 2003 May;14(4):339-46.

PMID:
12846365
37.

CYP1A1 and GSTM1 genetic polymorphisms and lung cancer risk in Caucasian non-smokers: a pooled analysis.

Hung RJ, Boffetta P, Brockmöller J, Butkiewicz D, Cascorbi I, Clapper ML, Garte S, Haugen A, Hirvonen A, Anttila S, Kalina I, Le Marchand L, London SJ, Rannug A, Romkes M, Salagovic J, Schoket B, Gaspari L, Taioli E.

Carcinogenesis. 2003 May;24(5):875-82.

PMID:
12771031
38.

Polymorphisms in CYP1A1, GSTM1, GSTT1 and lung cancer below the age of 45 years.

Taioli E, Gaspari L, Benhamou S, Boffetta P, Brockmoller J, Butkiewicz D, Cascorbi I, Clapper ML, Dolzan V, Haugen A, Hirvonen A, Husgafvel-Pursiainen K, Kalina I, Kremers P, Le Marchand L, London S, Rannug A, Romkes M, Schoket B, Seidegard J, Strange RC, Stucker I, To-Figueras J, Garte S.

Int J Epidemiol. 2003 Feb;32(1):60-3.

PMID:
12690010
39.

CYP1A1 T3801 C polymorphism and lung cancer: a pooled analysis of 2451 cases and 3358 controls.

Vineis P, Veglia F, Benhamou S, Butkiewicz D, Cascorbi I, Clapper ML, Dolzan V, Haugen A, Hirvonen A, Ingelman-Sundberg M, Kihara M, Kiyohara C, Kremers P, Le Marchand L, Ohshima S, Pastorelli R, Rannug A, Romkes M, Schoket B, Shields P, Strange RC, Stucker I, Sugimura H, Garte S, Gaspari L, Taioli E.

Int J Cancer. 2003 May 1;104(5):650-7.

40.

Characterization of in vitro metabolites of the aryl hydrocarbon receptor ligand 6-formylindolo[3,2-b]carbazole by liquid chromatography-mass spectrometry and NMR.

Bergander L, Wahlström N, Alsberg T, Bergman J, Rannug A, Rannug U.

Drug Metab Dispos. 2003 Feb;31(2):233-41.

PMID:
12527705
41.

Constitutive and TCDD-induced expression of Ah receptor-responsive genes in the pituitary.

Huang P, Ceccatelli S, Håkansson H, Grandison L, Rannug A.

Neurotoxicology. 2002 Dec;23(6):783-93.

PMID:
12520768
42.

Detection and characterization of a novel functional polymorphism in the GSTT1 gene.

Alexandrie AK, Rannug A, Juronen E, Tasa G, Warholm M.

Pharmacogenetics. 2002 Nov;12(8):613-9.

PMID:
12439221
43.

Influence of metabolic genotypes on biomarkers of exposure to 1,3-butadiene in humans.

Fustinoni S, Soleo L, Warholm M, Begemann P, Rannug A, Neumann HG, Swenberg JA, Vimercati L, Colombi A.

Cancer Epidemiol Biomarkers Prev. 2002 Oct;11(10 Pt 1):1082-90.

44.

Meta- and pooled analyses of the effects of glutathione S-transferase M1 polymorphisms and smoking on lung cancer risk.

Benhamou S, Lee WJ, Alexandrie AK, Boffetta P, Bouchardy C, Butkiewicz D, Brockmöller J, Clapper ML, Daly A, Dolzan V, Ford J, Gaspari L, Haugen A, Hirvonen A, Husgafvel-Pursiainen K, Ingelman-Sundberg M, Kalina I, Kihara M, Kremers P, Le Marchand L, London SJ, Nazar-Stewart V, Onon-Kihara M, Rannug A, Romkes M, Ryberg D, Seidegard J, Shields P, Strange RC, Stücker I, To-Figueras J, Brennan P, Taioli E.

Carcinogenesis. 2002 Aug;23(8):1343-50. Erratum in: Carcinogenesis 2002 Oct;23(10):1771.

PMID:
12151353
45.

Microsomal epoxide hydrolase polymorphisms and lung cancer risk: a quantitative review.

Lee WJ, Brennan P, Boffetta P, London SJ, Benhamou S, Rannug A, To-Figueras J, Ingelman-Sundberg M, Shields P, Gaspari L, Taioli E.

Biomarkers. 2002 May-Jun;7(3):230-41. Review.

PMID:
12141066
46.

Cancer risk assessment, indicators, and guidelines for polycyclic aromatic hydrocarbons in the ambient air.

Boström CE, Gerde P, Hanberg A, Jernström B, Johansson C, Kyrklund T, Rannug A, Törnqvist M, Victorin K, Westerholm R.

Environ Health Perspect. 2002 Jun;110 Suppl 3:451-88. Review.

47.

Susceptibility factors and DNA adducts in peripheral blood mononuclear cells of aluminium smelter workers exposed to polycyclic aromatic hydrocarbons.

Tuominen R, Baranczewski P, Warholm M, Hagmar L, Möller L, Rannug A.

Arch Toxicol. 2002 Apr;76(3):178-86. Epub 2002 Mar 7.

PMID:
11967624
48.

A study on diurnal mRNA expression of CYP1A1, AHR, ARNT, and PER2 in rat pituitary and liver.

Huang P, Ceccatelli S, Rannug A.

Environ Toxicol Pharmacol. 2002 Mar;11(2):119-26.

PMID:
21782593
49.

The effect of relevant genotypes on PAH exposure-related biomarkers.

Kuljukka-Rabb T, Nylund L, Vaaranrinta R, Savela K, Mutanen P, Veidebaum T, Sorsa M, Rannug A, Peltonen K.

J Expo Anal Environ Epidemiol. 2002 Jan-Feb;12(1):81-91.

50.

Metabolic gene polymorphism frequencies in control populations.

Garte S, Gaspari L, Alexandrie AK, Ambrosone C, Autrup H, Autrup JL, Baranova H, Bathum L, Benhamou S, Boffetta P, Bouchardy C, Breskvar K, Brockmoller J, Cascorbi I, Clapper ML, Coutelle C, Daly A, Dell'Omo M, Dolzan V, Dresler CM, Fryer A, Haugen A, Hein DW, Hildesheim A, Hirvonen A, Hsieh LL, Ingelman-Sundberg M, Kalina I, Kang D, Kihara M, Kiyohara C, Kremers P, Lazarus P, Le Marchand L, Lechner MC, van Lieshout EM, London S, Manni JJ, Maugard CM, Morita S, Nazar-Stewart V, Noda K, Oda Y, Parl FF, Pastorelli R, Persson I, Peters WH, Rannug A, Rebbeck T, Risch A, Roelandt L, Romkes M, Ryberg D, Salagovic J, Schoket B, Seidegard J, Shields PG, Sim E, Sinnet D, Strange RC, Stücker I, Sugimura H, To-Figueras J, Vineis P, Yu MC, Taioli E.

Cancer Epidemiol Biomarkers Prev. 2001 Dec;10(12):1239-48.

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