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Items: 39

1.

Novel glycosylated human interferon alpha 2b expressed in glycoengineered Pichia pastoris and its biological activity: N-linked glycoengineering approach.

Katla S, Yoganand KNR, Hingane S, Ranjith Kumar CT, Anand B, Sivaprakasam S.

Enzyme Microb Technol. 2019 Sep;128:49-58. doi: 10.1016/j.enzmictec.2019.05.007. Epub 2019 May 15.

PMID:
31186110
2.

Potent Inhibition of Hepatitis E Virus Release by a Cyclic Peptide Inhibitor of the Interaction between Viral Open Reading Frame 3 Protein and Host Tumor Susceptibility Gene 101.

Anang S, Kaushik N, Hingane S, Kumari A, Gupta J, Asthana S, Shalimar, Nayak B, Ranjith-Kumar CT, Surjit M.

J Virol. 2018 Sep 26;92(20). pii: e00684-18. doi: 10.1128/JVI.00684-18. Print 2018 Oct 15.

3.

Host-Virus Protein Interaction Network Reveals the Involvement of Multiple Host Processes in the Life Cycle of Hepatitis E Virus.

Subramani C, Nair VP, Anang S, Mandal SD, Pareek M, Kaushik N, Srivastava A, Saha S, Shalimar, Nayak B, Ranjith-Kumar CT, Surjit M.

mSystems. 2018 Jan 23;3(1). pii: e00135-17. doi: 10.1128/mSystems.00135-17. eCollection 2018 Jan-Feb.

4.

Zinc Salts Block Hepatitis E Virus Replication by Inhibiting the Activity of Viral RNA-Dependent RNA Polymerase.

Kaushik N, Subramani C, Anang S, Muthumohan R, Shalimar, Nayak B, Ranjith-Kumar CT, Surjit M.

J Virol. 2017 Oct 13;91(21). pii: e00754-17. doi: 10.1128/JVI.00754-17. Print 2017 Nov 1.

5.

A screen for novel hepatitis C virus RdRp inhibitor identifies a broad-spectrum antiviral compound.

Madhvi A, Hingane S, Srivastav R, Joshi N, Subramani C, Muthumohan R, Khasa R, Varshney S, Kalia M, Vrati S, Surjit M, Ranjith-Kumar CT.

Sci Rep. 2017 Jul 19;7(1):5816. doi: 10.1038/s41598-017-04449-3.

6.

Identification of critical residues in Hepatitis E virus macro domain involved in its interaction with viral methyltransferase and ORF3 proteins.

Anang S, Subramani C, Nair VP, Kaul S, Kaushik N, Sharma C, Tiwari A, Ranjith-Kumar CT, Surjit M.

Sci Rep. 2016 Apr 26;6:25133. doi: 10.1038/srep25133.

7.

Endoplasmic Reticulum Stress Induced Synthesis of a Novel Viral Factor Mediates Efficient Replication of Genotype-1 Hepatitis E Virus.

Nair VP, Anang S, Subramani C, Madhvi A, Bakshi K, Srivastava A, Shalimar, Nayak B, Ranjith Kumar CT, Surjit M.

PLoS Pathog. 2016 Apr 1;12(4):e1005521. doi: 10.1371/journal.ppat.1005521. eCollection 2016 Apr.

8.

The juxtamembrane sequence of the Hepatitis C virus polymerase can affect RNA synthesis and inhibition by allosteric polymerase inhibitors.

Wen Y, Lin X, Fan B, Ranjith-Kumar CT, Kao CC.

Virus Genes. 2015 Aug;51(1):1-11. doi: 10.1007/s11262-015-1199-4. Epub 2015 Apr 18.

PMID:
25895103
9.

RNA binding by the NS3 protease of the hepatitis C virus.

Vaughan R, Li Y, Fan B, Ranjith-Kumar CT, Kao CC.

Virus Res. 2012 Oct;169(1):80-90. doi: 10.1016/j.virusres.2012.07.007. Epub 2012 Jul 16.

10.

RNA synthesis by the brome mosaic virus RNA-dependent RNA polymerase in human cells reveals requirements for de novo initiation and protein-protein interaction.

Subba-Reddy CV, Tragesser B, Xu Z, Stein B, Ranjith-Kumar CT, Kao CC.

J Virol. 2012 Apr;86(8):4317-27. doi: 10.1128/JVI.00069-12. Epub 2012 Feb 8.

11.

Biochemical study of the comparative inhibition of hepatitis C virus RNA polymerase by VX-222 and filibuvir.

Yi G, Deval J, Fan B, Cai H, Soulard C, Ranjith-Kumar CT, Smith DB, Blatt L, Beigelman L, Kao CC.

Antimicrob Agents Chemother. 2012 Feb;56(2):830-7. doi: 10.1128/AAC.05438-11. Epub 2011 Dec 5.

12.

LL37 and cationic peptides enhance TLR3 signaling by viral double-stranded RNAs.

Lai Y, Adhikarakunnathu S, Bhardwaj K, Ranjith-Kumar CT, Wen Y, Jordan JL, Wu LH, Dragnea B, San Mateo L, Kao CC.

PLoS One. 2011;6(10):e26632. doi: 10.1371/journal.pone.0026632. Epub 2011 Oct 21.

13.

Viral double-strand RNA-binding proteins can enhance innate immune signaling by toll-like Receptor 3.

Lai Y, Yi G, Chen A, Bhardwaj K, Tragesser BJ, Rodrigo A Valverde, Zlotnick A, Mukhopadhyay S, Ranjith-Kumar CT, Kao CC.

PLoS One. 2011;6(10):e25837. doi: 10.1371/journal.pone.0025837. Epub 2011 Oct 10.

14.

A cell-based assay for RNA synthesis by the HCV polymerase reveals new insights on mechanism of polymerase inhibitors and modulation by NS5A.

Ranjith-Kumar CT, Wen Y, Baxter N, Bhardwaj K, Cheng Kao C.

PLoS One. 2011;6(7):e22575. doi: 10.1371/journal.pone.0022575. Epub 2011 Jul 22.

15.

Biochemical Activities of the HCV NS5B RNA-Dependent RNA Polymerase.

Ranjith-Kumar CT, Kao CC.

In: Tan SL, editor. Hepatitis C Viruses: Genomes and Molecular Biology. Norfolk (UK): Horizon Bioscience; 2006. Chapter 10.

16.

Crystal structure of RIG-I C-terminal domain bound to blunt-ended double-strand RNA without 5' triphosphate.

Lu C, Ranjith-Kumar CT, Hao L, Kao CC, Li P.

Nucleic Acids Res. 2011 Mar;39(4):1565-75. doi: 10.1093/nar/gkq974. Epub 2010 Oct 20.

17.

Green tea catechin, epigallocatechin gallate, suppresses signaling by the dsRNA innate immune receptor RIG-I.

Ranjith-Kumar CT, Lai Y, Sarisky RT, Cheng Kao C.

PLoS One. 2010 Sep 22;5(9):e12878. doi: 10.1371/journal.pone.0012878.

18.

Secretion of the human Toll-like receptor 3 ectodomain is affected by single nucleotide polymorphisms and regulated by Unc93b1.

Qi R, Hoose S, Schreiter J, Sawant KV, Lamb R, Ranjith-Kumar CT, Mills J, San Mateo L, Jordan JL, Kao CC.

J Biol Chem. 2010 Nov 19;285(47):36635-44. doi: 10.1074/jbc.M110.144402. Epub 2010 Sep 20.

19.

The structural basis of 5' triphosphate double-stranded RNA recognition by RIG-I C-terminal domain.

Lu C, Xu H, Ranjith-Kumar CT, Brooks MT, Hou TY, Hu F, Herr AB, Strong RK, Kao CC, Li P.

Structure. 2010 Aug 11;18(8):1032-43. doi: 10.1016/j.str.2010.05.007. Epub 2010 Jul 15.

20.

The RIG-I-like receptor LGP2 recognizes the termini of double-stranded RNA.

Li X, Ranjith-Kumar CT, Brooks MT, Dharmaiah S, Herr AB, Kao C, Li P.

J Biol Chem. 2009 May 15;284(20):13881-91. doi: 10.1074/jbc.M900818200. Epub 2009 Mar 11.

21.

Agonist and antagonist recognition by RIG-I, a cytoplasmic innate immunity receptor.

Ranjith-Kumar CT, Murali A, Dong W, Srisathiyanarayanan D, Vaughan R, Ortiz-Alacantara J, Bhardwaj K, Li X, Li P, Kao CC.

J Biol Chem. 2009 Jan 9;284(2):1155-65. doi: 10.1074/jbc.M806219200. Epub 2008 Nov 19.

22.

Single-stranded oligonucleotides can inhibit cytokine production induced by human toll-like receptor 3.

Ranjith-Kumar CT, Duffy KE, Jordan JL, Eaton-Bassiri A, Vaughan R, Hoose SA, Lamb RJ, Sarisky RT, Kao CC.

Mol Cell Biol. 2008 Jul;28(14):4507-19. doi: 10.1128/MCB.00308-08. Epub 2008 May 19.

23.

Structure and function of LGP2, a DEX(D/H) helicase that regulates the innate immunity response.

Murali A, Li X, Ranjith-Kumar CT, Bhardwaj K, Holzenburg A, Li P, Kao CC.

J Biol Chem. 2008 Jun 6;283(23):15825-33. doi: 10.1074/jbc.M800542200. Epub 2008 Apr 14.

24.

Effects of single nucleotide polymorphisms on Toll-like receptor 3 activity and expression in cultured cells.

Ranjith-Kumar CT, Miller W, Sun J, Xiong J, Santos J, Yarbrough I, Lamb RJ, Mills J, Duffy KE, Hoose S, Cunningham M, Holzenburg A, Mbow ML, Sarisky RT, Kao CC.

J Biol Chem. 2007 Jun 15;282(24):17696-705. Epub 2007 Apr 13.

25.

Biochemical and functional analyses of the human Toll-like receptor 3 ectodomain.

Ranjith-Kumar CT, Miller W, Xiong J, Russell WK, Lamb R, Santos J, Duffy KE, Cleveland L, Park M, Bhardwaj K, Wu Z, Russell DH, Sarisky RT, Mbow ML, Kao CC.

J Biol Chem. 2007 Mar 9;282(10):7668-78. Epub 2007 Jan 5.

26.

Structural and functional analyses of the human Toll-like receptor 3. Role of glycosylation.

Sun J, Duffy KE, Ranjith-Kumar CT, Xiong J, Lamb RJ, Santos J, Masarapu H, Cunningham M, Holzenburg A, Sarisky RT, Mbow ML, Kao C.

J Biol Chem. 2006 Apr 21;281(16):11144-51. Epub 2006 Feb 16.

27.

Recombinant viral RdRps can initiate RNA synthesis from circular templates.

Ranjith-Kumar CT, Kao CC.

RNA. 2006 Feb;12(2):303-12. Epub 2005 Dec 22.

28.

Functional analysis of RNA binding by the hepatitis C virus RNA-dependent RNA polymerase.

Kim YC, Russell WK, Ranjith-Kumar CT, Thomson M, Russell DH, Kao CC.

J Biol Chem. 2005 Nov 11;280(45):38011-9. Epub 2005 Sep 14.

29.

De novo initiation pocket mutations have multiple effects on hepatitis C virus RNA-dependent RNA polymerase activities.

Ranjith-Kumar CT, Sarisky RT, Gutshall L, Thomson M, Kao CC.

J Virol. 2004 Nov;78(22):12207-17.

30.

Enzymatic activities of the GB virus-B RNA-dependent RNA polymerase.

Ranjith-Kumar CT, Santos JL, Gutshall LL, Johnston VK, Lin-Goerke J, Kim MJ, Porter DJ, Maley D, Greenwood C, Earnshaw DL, Baker A, Gu B, Silverman C, Sarisky RT, Kao C.

Virology. 2003 Aug 1;312(2):270-80.

31.

Multiple interactions within the hepatitis C virus RNA polymerase repress primer-dependent RNA synthesis.

Ranjith-Kumar CT, Gutshall L, Sarisky RT, Kao CC.

J Mol Biol. 2003 Jul 18;330(4):675-85.

PMID:
12850139
32.

Identification of Arabidopsis rat mutants.

Zhu Y, Nam J, Humara JM, Mysore KS, Lee LY, Cao H, Valentine L, Li J, Kaiser AD, Kopecky AL, Hwang HH, Bhattacharjee S, Rao PK, Tzfira T, Rajagopal J, Yi H, Veena, Yadav BS, Crane YM, Lin K, Larcher Y, Gelvin MJ, Knue M, Ramos C, Zhao X, Davis SJ, Kim SI, Ranjith-Kumar CT, Choi YJ, Hallan VK, Chattopadhyay S, Sui X, Ziemienowicz A, Matthysse AG, Citovsky V, Hohn B, Gelvin SB.

Plant Physiol. 2003 Jun;132(2):494-505.

33.

Enhancer-like activity of a brome mosaic virus RNA promoter.

Ranjith-Kumar CT, Zhang X, Kao CC.

J Virol. 2003 Feb;77(3):1830-9.

34.

Requirements for de novo initiation of RNA synthesis by recombinant flaviviral RNA-dependent RNA polymerases.

Ranjith-Kumar CT, Gutshall L, Kim MJ, Sarisky RT, Kao CC.

J Virol. 2002 Dec;76(24):12526-36.

35.

Mechanism of de novo initiation by the hepatitis C virus RNA-dependent RNA polymerase: role of divalent metals.

Ranjith-Kumar CT, Kim YC, Gutshall L, Silverman C, Khandekar S, Sarisky RT, Kao CC.

J Virol. 2002 Dec;76(24):12513-25.

36.

Terminal nucleotidyl transferase activity of recombinant Flaviviridae RNA-dependent RNA polymerases: implication for viral RNA synthesis.

Ranjith-Kumar CT, Gajewski J, Gutshall L, Maley D, Sarisky RT, Kao CC.

J Virol. 2001 Sep;75(18):8615-23.

37.

Genomic sequence of physalis mottle virus and its evolutionary relationship with other tymoviruses.

Ranjith-Kumar CT, Gopinath K, Jacob AN, Srividhya V, Elango P, Savithri HS.

Arch Virol. 1998;143(8):1489-500.

PMID:
9739328
38.

Assembly of physalis mottle virus capsid protein in escherichia coli and the role of amino acid carboxy termini in the formation of icosahedral particles

Sastri M, Kekuuda R, Gopinath K, Ranjith Kumar CT, Jagath JR, Savithri HS.

J Mol Biol. 1998 May 8;278(3):699. No abstract available.

PMID:
9600849

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