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Items: 33

1.

Synthesis and pharmacological characterization of a potent, orally active p38 kinase inhibitor.

Dumas J, Hatoum-Mokdad H, Sibley RN, Smith RA, Scott WJ, Khire U, Lee W, Wood J, Wolanin D, Cooley J, Bankston D, Redman AM, Schoenleber R, Caringal Y, Gunn D, Romero R, Osterhout M, Paulsen H, Housley TJ, Wilhelm SM, Pirro J, Chien DS, Ranges GE, Shrikhande A, Muzsi A, Bortolon E, Wakefield J, Gianpaolo Ostravage C, Bhargava A, Chau T.

Bioorg Med Chem Lett. 2002 Jun 17;12(12):1559-62.

PMID:
12039561
2.

p38 kinase inhibitors for the treatment of arthritis and osteoporosis: thienyl, furyl, and pyrrolyl ureas.

Redman AM, Johnson JS, Dally R, Swartz S, Wild H, Paulsen H, Caringal Y, Gunn D, Renick J, Osterhout M, Kingery-Wood J, Smith RA, Lee W, Dumas J, Wilhelm SM, Housley TJ, Bhargava A, Ranges GE, Shrikhande A, Young D, Bombara M, Scott WJ.

Bioorg Med Chem Lett. 2001 Jan 8;11(1):9-12.

PMID:
11140741
3.

1-Phenyl-5-pyrazolyl ureas: potent and selective p38 kinase inhibitors.

Dumas J, Hatoum-Mokdad H, Sibley R, Riedl B, Scott WJ, Monahan MK, Lowinger TB, Brennan C, Natero R, Turner T, Johnson JS, Schoenleber R, Bhargava A, Wilhelm SM, Housley TJ, Ranges GE, Shrikhande A.

Bioorg Med Chem Lett. 2000 Sep 18;10(18):2051-4.

PMID:
10999468
4.

Discovery of a new class of p38 kinase inhibitors.

Dumas J, Sibley R, Riedl B, Monahan MK, Lee W, Lowinger TB, Redman AM, Johnson JS, Kingery-Wood J, Scott WJ, Smith RA, Bobko M, Schoenleber R, Ranges GE, Housley TJ, Bhargava A, Wilhelm SM, Shrikhande A.

Bioorg Med Chem Lett. 2000 Sep 18;10(18):2047-50.

PMID:
10999467
5.

Flavonoids inhibit cytokine-induced endothelial cell adhesion protein gene expression.

Gerritsen ME, Carley WW, Ranges GE, Shen CP, Phan SA, Ligon GF, Perry CA.

Am J Pathol. 1995 Aug;147(2):278-92.

6.

Inhibition of ceramide pathway does not affect ability of TNF-alpha to activate nuclear factor-kappa B.

Johns LD, Sarr T, Ranges GE.

J Immunol. 1994 Jun 15;152(12):5877-82.

PMID:
8207213
7.

Cell contact between T cells and synovial fibroblasts causes induction of adhesion molecules and cytokines.

Bombara MP, Webb DL, Conrad P, Marlor CW, Sarr T, Ranges GE, Aune TM, Greve JM, Blue ML.

J Leukoc Biol. 1993 Nov;54(5):399-406.

PMID:
7693840
8.

Anti-tumor necrosis factor receptor and tumor necrosis factor agonist activity by an anti-idiotypic antibody.

Galloway CJ, Madanat MS, Sarr T, Espevik T, Dumas ML, Mitra G, Ranges GE.

Eur J Immunol. 1992 Nov;22(11):3045-8.

PMID:
1330580
9.

Chromosome assignments of the human TNF p55 and p75 receptor genes.

Brownell E, Ranges GE, Sarr T, Fiorentino L, Godfrey M, Pekar S, Hart J, Kamarck M, Rae PM, Ruddle FH, et al.

J Exp Zool. 1992 Jun 1;262(3):340-2.

PMID:
1322446
10.

Successful treatment of experimental allergic encephalomyelitis with transforming growth factor-beta 1.

Johns LD, Flanders KC, Ranges GE, Sriram S.

J Immunol. 1991 Sep 15;147(6):1792-6.

PMID:
1716279
11.
12.

Serotonin-activated signal transduction via serotonin receptors on Jurkat cells.

Aune TM, Kelley KA, Ranges GE, Bombara MP.

J Immunol. 1990 Sep 15;145(6):1826-31.

PMID:
2144010
13.

Effect of cytotoxic monoclonal antibody depletion of T-lymphocyte subpopulations on bleomycin-induced lung damage in C57BL/6J mice.

Janick-Buckner D, Ranges GE, Hacker MP.

Toxicol Appl Pharmacol. 1989 Sep 15;100(3):474-84.

PMID:
2476870
14.

Alteration of bronchoalveolar lavage cell populations following bleomycin treatment in mice.

Janick-Buckner D, Ranges GE, Hacker MP.

Toxicol Appl Pharmacol. 1989 Sep 15;100(3):465-73.

PMID:
2476869
15.

Chronic therapy with recombinant tumor necrosis factor-alpha in autoimmune NZB/NZW F1 mice.

Gordon C, Ranges GE, Greenspan JS, Wofsy D.

Clin Immunol Immunopathol. 1989 Sep;52(3):421-34.

PMID:
2758698
16.

Genomic cloning and heterologous expression of human differentiation-stimulating factor.

Lowe DG, Nunes W, Bombara M, McCabe S, Ranges GE, Henzel W, Tomida M, Yamamoto-Yamaguchi Y, Hozumi M, Goeddel DV.

DNA. 1989 Jun;8(5):351-9.

PMID:
2475312
17.

Tumor necrosis factor-alpha as a proliferative signal for an IL-2-dependent T cell line: strict species specificity of action.

Ranges GE, Bombara MP, Aiyer RA, Rice GG, Palladino MA Jr.

J Immunol. 1989 Feb 15;142(4):1203-8.

PMID:
2536768
18.
19.

In vivo modulation of murine collagen induced arthritis.

Ranges GE, Fortin S, Barger MT, Sriram S, Cooper SM.

Int Rev Immunol. 1988 Sep;4(1):83-90. Review.

PMID:
3149663
20.

The involvement of human tumor necrosis factors-alpha and -beta in the mixed lymphocyte reaction.

Shalaby MR, Espevik T, Rice GC, Ammann AJ, Figari IS, Ranges GE, Palladino MA Jr.

J Immunol. 1988 Jul 15;141(2):499-503.

PMID:
2968403
21.

Tumor necrosis factor alpha/cachectin is a growth factor for thymocytes. Synergistic interactions with other cytokines.

Ranges GE, Zlotnik A, Espevik T, Dinarello CA, Cerami A, Palladino MA Jr.

J Exp Med. 1988 Apr 1;167(4):1472-8.

23.
24.

In vivo immunomodulation by monoclonal anti-L3T4. 1. Effects on humoral and cell-mediated immune response.

Ranges GE, Cooper SM, Sriram S.

Cell Immunol. 1987 Apr 15;106(1):163-73.

PMID:
3494534
25.

Immunotherapy of autoimmune disease with T cell subset specific antibodies.

Sriram S, Ranges GE.

Concepts Immunopathol. 1987;4:275-86. Review. No abstract available.

PMID:
3297338
26.

Development of T-cell function in relation to T-cell set diversification in nu/nu mice.

Ranges GE, Palladino MA Jr, Scheid MP.

Cell Immunol. 1986 Apr 1;98(2):496-505.

PMID:
2944619
27.

Prevention of type II collagen-induced arthritis by in vivo treatment with anti-L3T4.

Ranges GE, Sriram S, Cooper SM.

J Exp Med. 1985 Sep 1;162(3):1105-10.

29.

Functional relationships of Lyt-2 and Lyt-3 expression and T-cell cytotoxicity: a new model system.

Palladino MA Jr, Ranges GE, Oettgen HF, Old LJ.

Adv Exp Med Biol. 1985;184:355-64.

PMID:
3875974
30.

Suppression of T cell cytotoxicity by nude mouse spleen cells: reversal by monosaccharides and interleukin 2.

Palladino MA, Ranges GE, Scheid MP, Oettgen HF.

J Immunol. 1983 May;130(5):2200-2.

PMID:
6220084
31.

T cell development in normal and thymopentin-treated nude mice.

Ranges GE, Goldstein G, Boyse EA, Schield MP.

J Exp Med. 1982 Oct 1;156(4):1057-64.

32.

Inheritance of tolerance susceptibility to human gamma-globulin in congenic mice.

Ranges GE, Azar MM.

J Immunol. 1979 Sep;123(3):1151-4.

PMID:
89162
33.

Genetic control of tolerance induction to human gamma-globulin in mice.

Azar MM, Ranges GE, Yunis EJ, Clark C.

J Immunol. 1978 Oct;121(4):1251-6.

PMID:
81225

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