Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 67

1.

Group 3 innate lymphoid cells mediate early protective immunity against tuberculosis.

Ardain A, Domingo-Gonzalez R, Das S, Kazer SW, Howard NC, Singh A, Ahmed M, Nhamoyebonde S, Rangel-Moreno J, Ogongo P, Lu L, Ramsuran D, de la Luz Garcia-Hernandez M, K Ulland T, Darby M, Park E, Karim F, Melocchi L, Madansein R, Dullabh KJ, Dunlap M, Marin-Agudelo N, Ebihara T, Ndung'u T, Kaushal D, Pym AS, Kolls JK, Steyn A, Zúñiga J, Horsnell W, Yokoyama WM, Shalek AK, Kløverpris HN, Colonna M, Leslie A, Khader SA.

Nature. 2019 Jun 5. doi: 10.1038/s41586-019-1276-2. [Epub ahead of print]

PMID:
31168092
2.

Protective role of B cells in sterile particulate-induced lung injury.

Atif SM, Mack DG, McKee AS, Rangel-Moreno J, Martin AK, Getahun A, Maier LA, Cambier JC, Tuder R, Fontenot AP.

JCI Insight. 2019 May 16;5. pii: 125494. doi: 10.1172/jci.insight.125494.

3.

Defining inflammatory cell states in rheumatoid arthritis joint synovial tissues by integrating single-cell transcriptomics and mass cytometry.

Zhang F, Wei K, Slowikowski K, Fonseka CY, Rao DA, Kelly S, Goodman SM, Tabechian D, Hughes LB, Salomon-Escoto K, Watts GFM, Jonsson AH, Rangel-Moreno J, Meednu N, Rozo C, Apruzzese W, Eisenhaure TM, Lieb DJ, Boyle DL, Mandelin AM 2nd; Accelerating Medicines Partnership Rheumatoid Arthritis and Systemic Lupus Erythematosus (AMP RA/SLE) Consortium, Boyce BF, DiCarlo E, Gravallese EM, Gregersen PK, Moreland L, Firestein GS, Hacohen N, Nusbaum C, Lederer JA, Perlman H, Pitzalis C, Filer A, Holers VM, Bykerk VP, Donlin LT, Anolik JH, Brenner MB, Raychaudhuri S.

Nat Immunol. 2019 May 6. doi: 10.1038/s41590-019-0378-1. [Epub ahead of print]

PMID:
31061532
4.

Selective sexual dimorphism in musculoskeletal-cardiopulmonary pathologies and mortality in the TNF-transgenic mouse model of rheumatoid arthritis.

Bell DR, Wu E, Rudmann C, Forney M, Kaiser C, Wood R, Chakkalakal J, Paris N, Klose A, Xiao GQ, Rangel-Moreno J, Garcia-Hernandez M, Ritchlin C, Schwarz E, Rahimi H.

Arthritis Rheumatol. 2019 Apr 10. doi: 10.1002/art.40903. [Epub ahead of print]

PMID:
30969024
5.

A Novel Fluorescent and Bioluminescent Bireporter Influenza A Virus To Evaluate Viral Infections.

Nogales A, Ávila-Pérez G, Rangel-Moreno J, Chiem K, DeDiego ML, Martínez-Sobrido L.

J Virol. 2019 May 1;93(10). pii: e00032-19. doi: 10.1128/JVI.00032-19. Print 2019 May 15.

PMID:
30867298
6.

Epigenetic Suppression of SERPINB1 Promotes Inflammation-Mediated Prostate Cancer Progression.

Lerman I, Ma X, Seger C, Maolake A, Garcia-Hernandez ML, Rangel-Moreno J, Ackerman J, Nastiuk KL, Susiarjo M, Hammes SR.

Mol Cancer Res. 2019 Apr;17(4):845-859. doi: 10.1158/1541-7786.MCR-18-0638. Epub 2019 Jan 4.

PMID:
30610107
7.

B cells inhibit bone formation in rheumatoid arthritis by suppressing osteoblast differentiation.

Sun W, Meednu N, Rosenberg A, Rangel-Moreno J, Wang V, Glanzman J, Owen T, Zhou X, Zhang H, Boyce BF, Anolik JH, Xing L.

Nat Commun. 2018 Dec 3;9(1):5127. doi: 10.1038/s41467-018-07626-8.

8.

STAT2 Signaling Regulates Macrophage Phenotype During Influenza and Bacterial Super-Infection.

Gopal R, Lee B, McHugh KJ, Rich HE, Ramanan K, Mandalapu S, Clay ME, Seger PJ, Enelow RI, Manni ML, Robinson KM, Rangel-Moreno J, Alcorn JF.

Front Immunol. 2018 Sep 25;9:2151. doi: 10.3389/fimmu.2018.02151. eCollection 2018.

9.

Publisher Correction: Mycobacterium tuberculosis carrying a rifampicin drug resistance mutation reprograms macrophage metabolism through cell wall lipid changes.

Howard NC, Marin ND, Ahmed M, Rosa BA, Martin J, Bambouskova M, Sergushichev A, Loginicheva E, Kurepina N, Rangel-Moreno J, Chen L, Kreiswirth BN, Klein RS, Balada-Llasat JM, Torrelles JB, Amarasinghe GK, Mitreva M, Artyomov MN, Hsu FF, Mathema B, Khader SA.

Nat Microbiol. 2018 Nov;3(11):1327. doi: 10.1038/s41564-018-0281-9.

PMID:
30327492
10.

Mycobacterium tuberculosis carrying a rifampicin drug resistance mutation reprograms macrophage metabolism through cell wall lipid changes.

Howard NC, Marin ND, Ahmed M, Rosa BA, Martin J, Bambouskova M, Sergushichev A, Loginicheva E, Kurepina N, Rangel-Moreno J, Chen L, Kreiswirth BN, Klein RS, Balada-Llasat JM, Torrelles JB, Amarasinghe GK, Mitreva M, Artyomov MN, Hsu FF, Mathema B, Khader SA.

Nat Microbiol. 2018 Oct;3(10):1099-1108. doi: 10.1038/s41564-018-0245-0. Epub 2018 Sep 17. Erratum in: Nat Microbiol. 2018 Nov;3(11):1327.

11.

A novel role for C-C motif chemokine receptor 2 during infection with hypervirulent Mycobacterium tuberculosis.

Dunlap MD, Howard N, Das S, Scott N, Ahmed M, Prince O, Rangel-Moreno J, Rosa BA, Martin J, Kaushal D, Kaplan G, Mitreva M, Kim KW, Randolph GJ, Khader SA.

Mucosal Immunol. 2018 Nov;11(6):1727-1742. doi: 10.1038/s41385-018-0071-y. Epub 2018 Aug 16.

12.

Genetic ablation of histone deacetylase 2 leads to lung cellular senescence and lymphoid follicle formation in COPD/emphysema.

Sundar IK, Rashid K, Gerloff J, Rangel-Moreno J, Li D, Rahman I.

FASEB J. 2018 Sep;32(9):4955-4971. doi: 10.1096/fj.201701518R. Epub 2018 Apr 9.

PMID:
29630406
13.

Interleukin-17 limits hypoxia-inducible factor 1α and development of hypoxic granulomas during tuberculosis.

Domingo-Gonzalez R, Das S, Griffiths KL, Ahmed M, Bambouskova M, Gopal R, Gondi S, Muñoz-Torrico M, Salazar-Lezama MA, Cruz-Lagunas A, Jiménez-Álvarez L, Ramirez-Martinez G, Espinosa-Soto R, Sultana T, Lyons-Weiler J, Reinhart TA, Arcos J, de la Luz Garcia-Hernandez M, Mastrangelo MA, Al-Hammadi N, Townsend R, Balada-Llasat JM, Torrelles JB, Kaplan G, Horne W, Kolls JK, Artyomov MN, Rangel-Moreno J, Zúñiga J, Khader SA.

JCI Insight. 2017 Oct 5;2(19). pii: 92973. doi: 10.1172/jci.insight.92973.

14.

A novel nanoemulsion vaccine induces mucosal Interleukin-17 responses and confers protection upon Mycobacterium tuberculosis challenge in mice.

Ahmed M, Smith DM, Hamouda T, Rangel-Moreno J, Fattom A, Khader SA.

Vaccine. 2017 Sep 5;35(37):4983-4989. doi: 10.1016/j.vaccine.2017.07.073. Epub 2017 Jul 31.

15.

Neutrophils Slow Disease Progression in Murine Lupus via Modulation of Autoreactive Germinal Centers.

Bird AK, Chang M, Barnard J, Goldman BI, Meednu N, Rangel-Moreno J, Anolik JH.

J Immunol. 2017 Jul 15;199(2):458-466. doi: 10.4049/jimmunol.1700354. Epub 2017 Jun 5.

16.

A Unique Cellular and Molecular Microenvironment Is Present in Tertiary Lymphoid Organs of Patients with Spontaneous Prostate Cancer Regression.

García-Hernández ML, Uribe-Uribe NO, Espinosa-González R, Kast WM, Khader SA, Rangel-Moreno J.

Front Immunol. 2017 May 17;8:563. doi: 10.3389/fimmu.2017.00563. eCollection 2017.

17.

Infiltrating Myeloid Cells Exert Protumorigenic Actions via Neutrophil Elastase.

Lerman I, Garcia-Hernandez ML, Rangel-Moreno J, Chiriboga L, Pan C, Nastiuk KL, Krolewski JJ, Sen A, Hammes SR.

Mol Cancer Res. 2017 Sep;15(9):1138-1152. doi: 10.1158/1541-7786.MCR-17-0003. Epub 2017 May 16.

18.

Pneumocystis-Driven Inducible Bronchus-Associated Lymphoid Tissue Formation Requires Th2 and Th17 Immunity.

Eddens T, Elsegeiny W, Garcia-Hernadez ML, Castillo P, Trevejo-Nunez G, Serody K, Campfield BT, Khader SA, Chen K, Rangel-Moreno J, Kolls JK.

Cell Rep. 2017 Mar 28;18(13):3078-3090. doi: 10.1016/j.celrep.2017.03.016.

19.

Rationalized design of a mucosal vaccine protects against Mycobacterium tuberculosis challenge in mice.

Ahmed M, Jiao H, Domingo-Gonzalez R, Das S, Griffiths KL, Rangel-Moreno J, Nagarajan UM, Khader SA.

J Leukoc Biol. 2017 Jun;101(6):1373-1381. doi: 10.1189/jlb.4A0616-270R. Epub 2017 Mar 3.

20.

Novel role for IL-22 in protection during chronic Mycobacterium tuberculosis HN878 infection.

Treerat P, Prince O, Cruz-Lagunas A, Muñoz-Torrico M, Salazar-Lezama MA, Selman M, Fallert-Junecko B, Reinhardt TA, Alcorn JF, Kaushal D, Zuñiga J, Rangel-Moreno J, Kolls JK, Khader SA.

Mucosal Immunol. 2017 Jul;10(4):1069-1081. doi: 10.1038/mi.2017.15. Epub 2017 Mar 1.

21.

HLA Alleles are Genetic Markers for Susceptibility and Resistance towards Leprosy in a Mexican Mestizo Population.

Aguilar-Medina M, Escamilla-Tilch M, Frías-Castro LO, Romero-Quintana G, Estrada-García I, Estrada-Parra S, Granados J, Arambula Meraz E, Sánchez-Schmitz G, Khader SA, Rangel-Moreno J, Ramos-Payán R.

Ann Hum Genet. 2017 Jan;81(1):35-40. doi: 10.1111/ahg.12183. Epub 2016 Dec 27.

22.

Targeting dendritic cells to accelerate T-cell activation overcomes a bottleneck in tuberculosis vaccine efficacy.

Griffiths KL, Ahmed M, Das S, Gopal R, Horne W, Connell TD, Moynihan KD, Kolls JK, Irvine DJ, Artyomov MN, Rangel-Moreno J, Khader SA.

Nat Commun. 2016 Dec 22;7:13894. doi: 10.1038/ncomms13894.

23.

Serpine2 deficiency results in lung lymphocyte accumulation and bronchus-associated lymphoid tissue formation.

Solleti SK, Srisuma S, Bhattacharya S, Rangel-Moreno J, Bijli KM, Randall TD, Rahman A, Mariani TJ.

FASEB J. 2016 Jul;30(7):2615-26. doi: 10.1096/fj.201500159R. Epub 2016 Apr 8.

24.

Inhibition of G Protein βγ Subunit Signaling Abrogates Nephritis in Lupus-Prone Mice.

Rangel-Moreno J, To JY, Owen T, Goldman BI, Smrcka AV, Anolik JH.

Arthritis Rheumatol. 2016 Sep;68(9):2244-56. doi: 10.1002/art.39673.

25.

Helminth-induced arginase-1 exacerbates lung inflammation and disease severity in tuberculosis.

Monin L, Griffiths KL, Lam WY, Gopal R, Kang DD, Ahmed M, Rajamanickam A, Cruz-Lagunas A, Zúñiga J, Babu S, Kolls JK, Mitreva M, Rosa BA, Ramos-Payan R, Morrison TE, Murray PJ, Rangel-Moreno J, Pearce EJ, Khader SA.

J Clin Invest. 2015 Dec;125(12):4699-713. doi: 10.1172/JCI77378. Epub 2015 Nov 16.

26.

Production of RANKL by Memory B Cells: A Link Between B Cells and Bone Erosion in Rheumatoid Arthritis.

Meednu N, Zhang H, Owen T, Sun W, Wang V, Cistrone C, Rangel-Moreno J, Xing L, Anolik JH.

Arthritis Rheumatol. 2016 Apr;68(4):805-16. doi: 10.1002/art.39489.

27.

Successive Intramuscular Boosting with IFN-Alpha Protects Mycobacterium bovis BCG-Vaccinated Mice against M. lepraemurium Infection.

Guerrero GG, Rangel-Moreno J, Islas-Trujillo S, Rojas-Espinosa Ó.

Biomed Res Int. 2015;2015:414027. doi: 10.1155/2015/414027. Epub 2015 Sep 21.

28.

Mucosal vaccination with attenuated Mycobacterium tuberculosis induces strong central memory responses and protects against tuberculosis.

Kaushal D, Foreman TW, Gautam US, Alvarez X, Adekambi T, Rangel-Moreno J, Golden NA, Johnson AM, Phillips BL, Ahsan MH, Russell-Lodrigue KE, Doyle LA, Roy CJ, Didier PJ, Blanchard JL, Rengarajan J, Lackner AA, Khader SA, Mehra S.

Nat Commun. 2015 Oct 13;6:8533. doi: 10.1038/ncomms9533.

29.

Long-Lasting Impact of Neonatal Exposure to Total Body Gamma Radiation on Secondary Lymphoid Organ Structure and Function.

Rangel-Moreno J, de la Luz Garcia-Hernandez M, Ramos-Payan R, Biear J, Hernady E, Sangster MY, Randall TD, Johnston CJ, Finkelstein JN, Williams JP.

Radiat Res. 2015 Oct;184(4):352-66. doi: 10.1667/RR14047.1. Epub 2015 Sep 23.

30.

IL-22 regulates lymphoid chemokine production and assembly of tertiary lymphoid organs.

Barone F, Nayar S, Campos J, Cloake T, Withers DR, Toellner KM, Zhang Y, Fouser L, Fisher B, Bowman S, Rangel-Moreno J, Garcia-Hernandez Mde L, Randall TD, Lucchesi D, Bombardieri M, Pitzalis C, Luther SA, Buckley CD.

Proc Natl Acad Sci U S A. 2015 Sep 1;112(35):11024-9. doi: 10.1073/pnas.1503315112. Epub 2015 Aug 18.

31.

Immune requirements for protective Th17 recall responses to Mycobacterium tuberculosis challenge.

Monin L, Griffiths KL, Slight S, Lin Y, Rangel-Moreno J, Khader SA.

Mucosal Immunol. 2015 Sep;8(5):1099-109. doi: 10.1038/mi.2014.136. Epub 2015 Jan 28.

32.

Unexpected role for IL-17 in protective immunity against hypervirulent Mycobacterium tuberculosis HN878 infection.

Gopal R, Monin L, Slight S, Uche U, Blanchard E, Fallert Junecko BA, Ramos-Payan R, Stallings CL, Reinhart TA, Kolls JK, Kaushal D, Nagarajan U, Rangel-Moreno J, Khader SA.

PLoS Pathog. 2014 May 15;10(5):e1004099. doi: 10.1371/journal.ppat.1004099. eCollection 2014 May.

33.

Long-term B cell depletion in murine lupus eliminates autoantibody-secreting cells and is associated with alterations in the kidney plasma cell niche.

Wang W, Rangel-Moreno J, Owen T, Barnard J, Nevarez S, Ichikawa HT, Anolik JH.

J Immunol. 2014 Apr 1;192(7):3011-20. doi: 10.4049/jimmunol.1302003. Epub 2014 Feb 26.

34.

Neutrophil-mediated IFN activation in the bone marrow alters B cell development in human and murine systemic lupus erythematosus.

Palanichamy A, Bauer JW, Yalavarthi S, Meednu N, Barnard J, Owen T, Cistrone C, Bird A, Rabinovich A, Nevarez S, Knight JS, Dedrick R, Rosenberg A, Wei C, Rangel-Moreno J, Liesveld J, Sanz I, Baechler E, Kaplan MJ, Anolik JH.

J Immunol. 2014 Feb 1;192(3):906-18. doi: 10.4049/jimmunol.1302112. Epub 2013 Dec 30.

35.

Mucosal pre-exposure to Th17-inducing adjuvants exacerbates pathology after influenza infection.

Gopal R, Rangel-Moreno J, Fallert Junecko BA, Mallon DJ, Chen K, Pociask DA, Connell TD, Reinhart TA, Alcorn JF, Ross TM, Kolls JK, Khader SA.

Am J Pathol. 2014 Jan;184(1):55-63. doi: 10.1016/j.ajpath.2013.09.012. Epub 2013 Nov 1.

36.

Selective ablation of lung epithelial IKK2 impairs pulmonary Th17 responses and delays the clearance of Pneumocystis.

Perez-Nazario N, Rangel-Moreno J, O'Reilly MA, Pasparakis M, Gigliotti F, Wright TW.

J Immunol. 2013 Nov 1;191(9):4720-30. doi: 10.4049/jimmunol.1301679. Epub 2013 Sep 27.

37.

S100A8/A9 proteins mediate neutrophilic inflammation and lung pathology during tuberculosis.

Gopal R, Monin L, Torres D, Slight S, Mehra S, McKenna KC, Fallert Junecko BA, Reinhart TA, Kolls J, Báez-Saldaña R, Cruz-Lagunas A, Rodríguez-Reyna TS, Kumar NP, Tessier P, Roth J, Selman M, Becerril-Villanueva E, Baquera-Heredia J, Cumming B, Kasprowicz VO, Steyn AJ, Babu S, Kaushal D, Zúñiga J, Vogl T, Rangel-Moreno J, Khader SA.

Am J Respir Crit Care Med. 2013 Nov 1;188(9):1137-46. doi: 10.1164/rccm.201304-0803OC.

38.

IL-10 restrains IL-17 to limit lung pathology characteristics following pulmonary infection with Francisella tularensis live vaccine strain.

Slight SR, Monin L, Gopal R, Avery L, Davis M, Cleveland H, Oury TD, Rangel-Moreno J, Khader SA.

Am J Pathol. 2013 Nov;183(5):1397-1404. doi: 10.1016/j.ajpath.2013.07.008. Epub 2013 Sep 3.

39.

Pulmonary expression of oncostatin M (OSM) promotes inducible BALT formation independently of IL-6, despite a role for IL-6 in OSM-driven pulmonary inflammation.

Botelho FM, Rangel-Moreno J, Fritz D, Randall TD, Xing Z, Richards CD.

J Immunol. 2013 Aug 1;191(3):1453-64. doi: 10.4049/jimmunol.1203318. Epub 2013 Jun 24.

40.

Differential and site specific impact of B cells in the protective immune response to Mycobacterium tuberculosis in the mouse.

Torrado E, Fountain JJ, Robinson RT, Martino CA, Pearl JE, Rangel-Moreno J, Tighe M, Dunn R, Cooper AM.

PLoS One. 2013 Apr 16;8(4):e61681. doi: 10.1371/journal.pone.0061681. Print 2013.

41.

Neonatal irradiation sensitizes mice to delayed pulmonary challenge.

Johnston CJ, Manning CM, Rangel-Moreno J, Randall TD, Hernady E, Finkelstein JN, Williams JP.

Radiat Res. 2013 Apr;179(4):475-84. doi: 10.1667/RR3242.1. Epub 2012 Mar 15.

42.

Interleukin-17-dependent CXCL13 mediates mucosal vaccine-induced immunity against tuberculosis.

Gopal R, Rangel-Moreno J, Slight S, Lin Y, Nawar HF, Fallert Junecko BA, Reinhart TA, Kolls J, Randall TD, Connell TD, Khader SA.

Mucosal Immunol. 2013 Sep;6(5):972-84. doi: 10.1038/mi.2012.135. Epub 2013 Jan 9.

43.

CXCR5⁺ T helper cells mediate protective immunity against tuberculosis.

Slight SR, Rangel-Moreno J, Gopal R, Lin Y, Fallert Junecko BA, Mehra S, Selman M, Becerril-Villanueva E, Baquera-Heredia J, Pavon L, Kaushal D, Reinhart TA, Randall TD, Khader SA.

J Clin Invest. 2013 Feb;123(2):712-26. doi: 10.1172/JCI65728. Epub 2013 Jan 2.

44.

Lipocalin 2 regulates inflammation during pulmonary mycobacterial infections.

Guglani L, Gopal R, Rangel-Moreno J, Junecko BF, Lin Y, Berger T, Mak TW, Alcorn JF, Randall TD, Reinhart TA, Chan YR, Khader SA.

PLoS One. 2012;7(11):e50052. doi: 10.1371/journal.pone.0050052. Epub 2012 Nov 20.

45.

IL-23 is required for long-term control of Mycobacterium tuberculosis and B cell follicle formation in the infected lung.

Khader SA, Guglani L, Rangel-Moreno J, Gopal R, Junecko BA, Fountain JJ, Martino C, Pearl JE, Tighe M, Lin YY, Slight S, Kolls JK, Reinhart TA, Randall TD, Cooper AM.

J Immunol. 2011 Nov 15;187(10):5402-7. doi: 10.4049/jimmunol.1101377. Epub 2011 Oct 14.

46.

The development of inducible bronchus-associated lymphoid tissue depends on IL-17.

Rangel-Moreno J, Carragher DM, de la Luz Garcia-Hernandez M, Hwang JY, Kusser K, Hartson L, Kolls JK, Khader SA, Randall TD.

Nat Immunol. 2011 Jun 12;12(7):639-46. doi: 10.1038/ni.2053.

47.

Antigen-specific clonal expansion and cytolytic effector function of CD8+ T lymphocytes depend on the transcription factor Bcl11b.

Zhang S, Rozell M, Verma RK, Albu DI, Califano D, VanValkenburgh J, Merchant A, Rangel-Moreno J, Randall TD, Jenkins NA, Copeland NG, Liu P, Avram D.

J Exp Med. 2010 Aug 2;207(8):1687-99. doi: 10.1084/jem.20092136. Epub 2010 Jul 26.

48.

Pathological role of interleukin 17 in mice subjected to repeated BCG vaccination after infection with Mycobacterium tuberculosis.

Cruz A, Fraga AG, Fountain JJ, Rangel-Moreno J, Torrado E, Saraiva M, Pereira DR, Randall TD, Pedrosa J, Cooper AM, Castro AG.

J Exp Med. 2010 Aug 2;207(8):1609-16. doi: 10.1084/jem.20100265. Epub 2010 Jul 12.

49.

Bronchus-associated lymphoid tissue (BALT) and survival in a vaccine mouse model of tularemia.

Chiavolini D, Rangel-Moreno J, Berg G, Christian K, Oliveira-Nascimento L, Weir S, Alroy J, Randall TD, Wetzler LM.

PLoS One. 2010 Jun 16;5(6):e11156. doi: 10.1371/journal.pone.0011156.

50.

In a murine tuberculosis model, the absence of homeostatic chemokines delays granuloma formation and protective immunity.

Khader SA, Rangel-Moreno J, Fountain JJ, Martino CA, Reiley WW, Pearl JE, Winslow GM, Woodland DL, Randall TD, Cooper AM.

J Immunol. 2009 Dec 15;183(12):8004-14. doi: 10.4049/jimmunol.0901937.

Supplemental Content

Loading ...
Support Center