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Items: 41

1.

Targeting Heparanase in Cancer: Inhibition by Synthetic, Chemically Modified, and Natural Compounds.

Mohan CD, Hari S, Preetham HD, Rangappa S, Barash U, Ilan N, Nayak SC, Gupta VK, Basappa, Vlodavsky I, Rangappa KS.

iScience. 2019 May 3;15:360-390. doi: 10.1016/j.isci.2019.04.034. [Epub ahead of print] Review.

2.

Evaluation of soluble fentanyl microneedles for loco-regional anti-nociceptive activity.

Maurya A, Rangappa S, Bae J, Dhawan T, Ajjarapu SS, Murthy SN.

Int J Pharm. 2019 Jun 10;564:485-491. doi: 10.1016/j.ijpharm.2019.04.066. Epub 2019 Apr 23.

PMID:
31026490
3.

Urinary protein carbonyl levels and its correlation with protein misfolding in preeclampsia.

Nagarajappa C, Rangappa SS, Suryanarayana R, Balakrishna S.

Hypertens Pregnancy. 2019 May;38(2):124-128. doi: 10.1080/10641955.2019.1590720. Epub 2019 Mar 26.

PMID:
30913931
4.

Synthesis of CC, CN coupled novel substituted dibutyl benzothiazepinone derivatives and evaluation of their thrombin inhibitory activity.

Baburajeev CP, Mohan CD, Pandey V, Rangappa S, Shivalingegowda N, Kalash L, Devaraja S, Bender A, Lobie PE, Rangappa KS, Basappa.

Bioorg Chem. 2019 Mar 5;87:142-154. doi: 10.1016/j.bioorg.2019.03.004. [Epub ahead of print]

PMID:
30884308
5.

Sulfated Ceria Catalyzed Synthesis of Imidazopyridines and Their Implementation as DNA Minor Groove Binders.

Mohan S, Rangappa S, Anilkumar NC, Fuchs JE, Bender A, Basappa, Rangappa KS, Bhatnagar R.

Chem Biodivers. 2019 May;16(5):e1800435. doi: 10.1002/cbdv.201800435. Epub 2019 Apr 10.

PMID:
30702795
6.

Healthy human serum N-glycan profiling reveals the influence of ethnic variation on the identified cancer-relevant glycan biomarkers.

Gebrehiwot AG, Melka DS, Kassaye YM, Rehan IF, Rangappa S, Hinou H, Kamiyama T, Nishimura SI.

PLoS One. 2018 Dec 28;13(12):e0209515. doi: 10.1371/journal.pone.0209515. eCollection 2018.

7.

N-Substituted Pyrido-1,4-Oxazin-3-Ones Induce Apoptosis of Hepatocellular Carcinoma Cells by Targeting NF-κB Signaling Pathway.

Mohan CD, Bharathkumar H, Dukanya, Rangappa S, Shanmugam MK, Chinnathambi A, Alharbi SA, Alahmadi TA, Bhattacharjee A, Lobie PE, Deivasigamani A, Hui KM, Sethi G, Basappa, Rangappa KS, Kumar AP.

Front Pharmacol. 2018 Nov 5;9:1125. doi: 10.3389/fphar.2018.01125. eCollection 2018.

8.

Urolithin A, a Novel Natural Compound to Target PI3K/AKT/mTOR Pathway in Pancreatic Cancer.

Totiger TM, Srinivasan S, Jala VR, Lamichhane P, Dosch AR, Gaidarski AA 3rd, Joshi C, Rangappa S, Castellanos J, Vemula PK, Chen X, Kwon D, Kashikar N, VanSaun M, Merchant NB, Nagathihalli NS.

Mol Cancer Ther. 2019 Feb;18(2):301-311. doi: 10.1158/1535-7163.MCT-18-0464. Epub 2018 Nov 7.

PMID:
30404927
9.

Discovery of a small-molecule inhibitor of specific serine residue BAD phosphorylation.

Pandey V, Wang B, Mohan CD, Raquib AR, Rangappa S, Srinivasa V, Fuchs JE, Girish KS, Zhu T, Bender A, Ma L, Yin Z, Basappa, Rangappa KS, Lobie PE.

Proc Natl Acad Sci U S A. 2018 Oct 30;115(44):E10505-E10514. doi: 10.1073/pnas.1804897115. Epub 2018 Oct 11.

10.

Urinary congophilia in preeclampsia: Experience from a rural tertiary-care hospital in India.

Nagarajappa C, Rangappa SS, Suryanarayana R, Balakrishna S.

Pregnancy Hypertens. 2018 Jul;13:83-86. doi: 10.1016/j.preghy.2018.05.006. Epub 2018 May 14.

PMID:
30177078
11.

Antiallodynic and Antihyperalgesic Activities of Fentanyl-Loaded Dermal Clay Dressings in Rat Model of Second-Degree Burn Injury.

Rangappa S, Rangan KK, Sudarshan TS, Murthy SN.

J Pharm Sci. 2018 Oct;107(10):2628-2634. doi: 10.1016/j.xphs.2018.06.005. Epub 2018 Jun 18.

PMID:
29920252
12.

Synthesis, characterization and cytotoxicity studies of 1,2,3-triazoles and 1,2,4-triazolo [1,5-a] pyrimidines in human breast cancer cells.

Gilandoust M, Harsha KB, Mohan CD, Raquib AR, Rangappa S, Pandey V, Lobie PE, Basappa, Rangappa KS.

Bioorg Med Chem Lett. 2018 Jul 15;28(13):2314-2319. doi: 10.1016/j.bmcl.2018.05.020. Epub 2018 May 9.

PMID:
29789259
13.

A trisubstituted pyrazole derivative reduces DMBA-induced mammary tumor growth in rats by inhibiting estrogen receptor-α expression.

Ananda H, Sharath Kumar KS, Sudhanva MS, Rangappa S, Rangappa KS.

Mol Cell Biochem. 2018 Dec;449(1-2):137-144. doi: 10.1007/s11010-018-3350-8. Epub 2018 May 18.

PMID:
29777335
14.

Endophytic Fungi-Alternative Sources of Cytotoxic Compounds: A Review.

Uzma F, Mohan CD, Hashem A, Konappa NM, Rangappa S, Kamath PV, Singh BP, Mudili V, Gupta VK, Siddaiah CN, Chowdappa S, Alqarawi AA, Abd Allah EF.

Front Pharmacol. 2018 Apr 26;9:309. doi: 10.3389/fphar.2018.00309. eCollection 2018. Review.

15.

Novel 1,3,4-Oxadiazole Induces Anticancer Activity by Targeting NF-κB in Hepatocellular Carcinoma Cells.

Mohan CD, Anilkumar NC, Rangappa S, Shanmugam MK, Mishra S, Chinnathambi A, Alharbi SA, Bhattacharjee A, Sethi G, Kumar AP, Basappa, Rangappa KS.

Front Oncol. 2018 Mar 19;8:42. doi: 10.3389/fonc.2018.00042. eCollection 2018.

16.

Correction: Novel Synthetic Oxazines Target NF-κB in Colon Cancer In Vitro and Inflammatory Bowel Disease In Vivo.

Nirvanappa AC, Mohan CD, Rangappa S, Ananda H, Sukhorukov AY, Shanmugam MK, Sundaram MS, Nayaka SC, Girish KS, Chinnathambi A, Zayed ME, Alharbi SA, Sethi G, Basappa, Rangappa KS.

PLoS One. 2017 Apr 6;12(4):e0175659. doi: 10.1371/journal.pone.0175659. eCollection 2017.

17.

Identification of Novel Class of Triazolo-Thiadiazoles as Potent Inhibitors of Human Heparanase and their Anticancer Activity.

Baburajeev CP, Mohan CD, Rangappa S, Mason DJ, Fuchs JE, Bender A, Barash U, Vlodavsky I, Basappa, Rangappa KS.

BMC Cancer. 2017 Mar 31;17(1):235. doi: 10.1186/s12885-017-3214-8.

18.

Elicitation of resistance and associated defense responses in Trichoderma hamatum induced protection against pearl millet downy mildew pathogen.

Siddaiah CN, Satyanarayana NR, Mudili V, Kumar Gupta V, Gurunathan S, Rangappa S, Huntrike SS, Srivastava RK.

Sci Rep. 2017 Mar 21;7:43991. doi: 10.1038/srep43991.

19.

Novel Adamantanyl-Based Thiadiazolyl Pyrazoles Targeting EGFR in Triple-Negative Breast Cancer.

Sebastian A, Pandey V, Mohan CD, Chia YT, Rangappa S, Mathai J, Baburajeev CP, Paricharak S, Mervin LH, Bulusu KC, Fuchs JE, Bender A, Yamada S, Basappa, Lobie PE, Rangappa KS.

ACS Omega. 2016 Dec 31;1(6):1412-1424. doi: 10.1021/acsomega.6b00251. Epub 2016 Dec 28.

20.

Novel Synthetic Oxazines Target NF-κB in Colon Cancer In Vitro and Inflammatory Bowel Disease In Vivo.

Nirvanappa AC, Mohan CD, Rangappa S, Ananda H, Sukhorukov AY, Shanmugam MK, Sundaram MS, Nayaka SC, Girish KS, Chinnathambi A, Zayed ME, Alharbi SA, Sethi G, Basappa, Rangappa KS.

PLoS One. 2016 Sep 29;11(9):e0163209. doi: 10.1371/journal.pone.0163209. eCollection 2016. Erratum in: PLoS One. 2017 Apr 6;12 (4):e0175659.

21.

Predominant mania course in Indian patients with bipolar I disorder.

Rangappa SB, Munivenkatappa S, Narayanaswamy JC, Jain S, Reddy YC.

Asian J Psychiatr. 2016 Aug;22:22-7. doi: 10.1016/j.ajp.2016.04.006. Epub 2016 Apr 25.

PMID:
27520890
22.

An azaspirane derivative suppresses growth and induces apoptosis of ER-positive and ER-negative breast cancer cells through the modulation of JAK2/STAT3 signaling pathway.

Sulaiman NB, Mohan CD, Basappa S, Pandey V, Rangappa S, Bharathkumar H, Kumar AP, Lobie PE, Rangappa KS.

Int J Oncol. 2016 Sep;49(3):1221-9. doi: 10.3892/ijo.2016.3615. Epub 2016 Jul 6.

PMID:
27500741
23.

Trisubstituted-Imidazoles Induce Apoptosis in Human Breast Cancer Cells by Targeting the Oncogenic PI3K/Akt/mTOR Signaling Pathway.

Mohan CD, Srinivasa V, Rangappa S, Mervin L, Mohan S, Paricharak S, Baday S, Li F, Shanmugam MK, Chinnathambi A, Zayed ME, Alharbi SA, Bender A, Sethi G, Basappa, Rangappa KS.

PLoS One. 2016 Apr 20;11(4):e0153155. doi: 10.1371/journal.pone.0153155. eCollection 2016.

24.

Adamantyl-tethered-biphenylic compounds induce apoptosis in cancer cells by targeting Bcl homologs.

Anusha S, Mohan CD, Ananda H, Baburajeev CP, Rangappa S, Mathai J, Fuchs JE, Li F, Shanmugam MK, Bender A, Sethi G, Basappa, Rangappa KS.

Bioorg Med Chem Lett. 2016 Feb 1;26(3):1056-1060. doi: 10.1016/j.bmcl.2015.12.026. Epub 2015 Dec 10.

PMID:
26725030
25.

A Nano-MgO and Ionic Liquid-Catalyzed 'Green' Synthesis Protocol for the Development of Adamantyl-Imidazolo-Thiadiazoles as Anti-Tuberculosis Agents Targeting Sterol 14α-Demethylase (CYP51).

Anusha S, Cp B, Mohan CD, Mathai J, Rangappa S, Mohan S, Chandra, Paricharak S, Mervin L, Fuchs JE, M M, Bender A, Basappa, Rangappa KS.

PLoS One. 2015 Oct 15;10(10):e0139798. doi: 10.1371/journal.pone.0139798. eCollection 2015.

26.

Development of Novel Triazolo-Thiadiazoles from Heterogeneous "Green" Catalysis as Protein Tyrosine Phosphatase 1B Inhibitors.

Baburajeev CP, Dhananjaya Mohan C, Ananda H, Rangappa S, Fuchs JE, Jagadish S, Sivaraman Siveen K, Chinnathambi A, Ali Alharbi S, Zayed ME, Zhang J, Li F, Sethi G, Girish KS, Bender A, Basappa, Rangappa KS.

Sci Rep. 2015 Sep 21;5:14195. doi: 10.1038/srep14195.

27.

Synthesis of 1,2-benzisoxazole tethered 1,2,3-triazoles that exhibit anticancer activity in acute myeloid leukemia cell lines by inhibiting histone deacetylases, and inducing p21 and tubulin acetylation.

Ashwini N, Garg M, Mohan CD, Fuchs JE, Rangappa S, Anusha S, Swaroop TR, Rakesh KS, Kanojia D, Madan V, Bender A, Koeffler HP, Basappa, Rangappa KS.

Bioorg Med Chem. 2015 Sep 15;23(18):6157-65. doi: 10.1016/j.bmc.2015.07.069. Epub 2015 Aug 1.

PMID:
26299825
28.

A One Pot Synthesis of Novel Bioactive Tri-Substitute-Condensed-Imidazopyridines that Targets Snake Venom Phospholipase A2.

Anilkumar NC, Sundaram MS, Mohan CD, Rangappa S, Bulusu KC, Fuchs JE, Girish KS, Bender A, Basappa, Rangappa KS.

PLoS One. 2015 Jul 21;10(7):e0131896. doi: 10.1371/journal.pone.0131896. eCollection 2015.

29.

Screening of quinoline, 1,3-benzoxazine, and 1,3-oxazine-based small molecules against isolated methionyl-tRNA synthetase and A549 and HCT116 cancer cells including an in silico binding mode analysis.

Bharathkumar H, Mohan CD, Rangappa S, Kang T, Keerthy HK, Fuchs JE, Kwon NH, Bender A, Kim S, Basappa, Rangappa KS.

Org Biomol Chem. 2015 Sep 28;13(36):9381-7. doi: 10.1039/c5ob00791g. Epub 2015 Jul 10.

PMID:
26159576
30.

Synthesis and characterization of novel oxazines and demonstration that they specifically target cyclooxygenase 2.

Srinivas V, Mohan CD, Baburajeev CP, Rangappa S, Jagadish S, Fuchs JE, Sukhorukov AY, Chandra, Mason DJ, Sharath Kumar KS, Madegowda M, Bender A, Basappa, Rangappa KS.

Bioorg Med Chem Lett. 2015 Aug 1;25(15):2931-6. doi: 10.1016/j.bmcl.2015.05.047. Epub 2015 May 27.

PMID:
26048794
31.

Microwave-assisted synthesis, characterization and cytotoxic studies of novel estrogen receptor α ligands towards human breast cancer cells.

Bharathkumar H, Mohan CD, Ananda H, Fuchs JE, Li F, Rangappa S, Surender M, Bulusu KC, Girish KS, Sethi G, Bender A, Basappa, Rangappa KS.

Bioorg Med Chem Lett. 2015 Apr 15;25(8):1804-1807. doi: 10.1016/j.bmcl.2015.01.030. Epub 2015 Feb 7.

PMID:
25797502
32.

Development of a novel azaspirane that targets the Janus kinase-signal transducer and activator of transcription (STAT) pathway in hepatocellular carcinoma in vitro and in vivo.

Mohan CD, Bharathkumar H, Bulusu KC, Pandey V, Rangappa S, Fuchs JE, Shanmugam MK, Dai X, Li F, Deivasigamani A, Hui KM, Kumar AP, Lobie PE, Bender A, Basappa, Sethi G, Rangappa KS.

J Biol Chem. 2014 Dec 5;289(49):34296-307. doi: 10.1074/jbc.M114.601104. Epub 2014 Oct 15.

33.

Novel synthetic biscoumarins target tumor necrosis factor-α in hepatocellular carcinoma in vitro and in vivo.

Keerthy HK, Mohan CD, Sivaraman Siveen K, Fuchs JE, Rangappa S, Sundaram MS, Li F, Girish KS, Sethi G, Basappa, Bender A, Rangappa KS.

J Biol Chem. 2014 Nov 14;289(46):31879-90. doi: 10.1074/jbc.M114.593855. Epub 2014 Sep 17.

34.

Rare occurrence of symphysis pubis diastasis following normal vaginal delivery.

Boraiah S, Krishna SA, Rangappa SS.

J Obstet Gynaecol India. 2013 Dec;63(6):418-9. doi: 10.1007/s13224-012-0252-7. Epub 2012 Sep 18. No abstract available.

35.

Synthesis and Anti-hyperlipidemic Activity of 3H-benzo [4, 5] thieno [2, 3-d] [1, 2, 3] triazin-4-ones: Possible Mechanism of Altered Lipid Metabolism.

Viswanatha GL; Janaki Priyadarshini B, Hanumanthappa S, Rangappa S, Janardhanan S.

Oman Med J. 2012 Sep;27(5):388-95. doi: 10.5001/omj.2012.96.

36.

Synthesis and antihistaminic activity of 3H-benzo [4,5] thieno [2,3-d][1,2,3] triazin-4-ones.

Viswanatha GL, Priyadarshini BJ, Krishnadas N, Janardhanan S, Rangappa S, Hanumanthappa S.

Saudi Pharm J. 2012 Jan;20(1):45-52. doi: 10.1016/j.jsps.2011.05.005. Epub 2011 May 24.

37.

Antidiarrheal effect of fractions from stem bark of Thespesia populnea in rodents: Possible antimotility and antisecretory mechanisms.

Viswanatha GL, Hanumanthappa S, Krishnadas N, Rangappa S.

Asian Pac J Trop Med. 2011 Jun;4(6):451-6. doi: 10.1016/S1995-7645(11)60124-7.

38.

Review article: current status of myocardial regeneration: new cell sources and new strategies.

Rangappa S, Makkar R, Forrester J.

J Cardiovasc Pharmacol Ther. 2010 Dec;15(4):338-43. doi: 10.1177/1074248410376382. Review.

PMID:
21098418
39.
40.

Cardiomyocyte-mediated contact programs human mesenchymal stem cells to express cardiogenic phenotype.

Rangappa S, Entwistle JW, Wechsler AS, Kresh JY.

J Thorac Cardiovasc Surg. 2003 Jul;126(1):124-32.

41.

Transformation of adult mesenchymal stem cells isolated from the fatty tissue into cardiomyocytes.

Rangappa S, Fen C, Lee EH, Bongso A, Sim EK.

Ann Thorac Surg. 2003 Mar;75(3):775-9. Erratum in: Ann Thorac Surg. 2004 May;77(5):1880. Wei, Eugene Sim Kwang [corrected to Sim, Eugene Kwang Wei].

PMID:
12645692

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