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Items: 1 to 50 of 230

1.

Plasma metabolomics profiles suggest beneficial effects of a low-glycemic load dietary pattern on inflammation and energy metabolism.

Navarro SL, Tarkhan A, Shojaie A, Randolph TW, Gu H, Djukovic D, Osterbauer KJ, Hullar MA, Kratz M, Neuhouser ML, Lampe PD, Raftery D, Lampe JW.

Am J Clin Nutr. 2019 Aug 20. pii: nqz169. doi: 10.1093/ajcn/nqz169. [Epub ahead of print]

PMID:
31432072
2.

Proteomic Analysis of Plasma Reveals Fat Mass Influences Cancer-Related Pathways in Healthy Humans Fed Controlled Diets Differing in Glycemic Load.

Garrison CB, Zhang Y, Navarro SL, Randolph TW, Hullar MAJ, Kratz M, Neuhouser ML, Raftery D, Lampe PD, Lampe JW.

Cancer Prev Res (Phila). 2019 Sep;12(9):567-578. doi: 10.1158/1940-6207.CAPR-19-0175. Epub 2019 Jul 2.

PMID:
31266826
3.

Differential DNA methylation in blood as a mediator of the association between cigarette smoking and bladder cancer risk among postmenopausal women.

Jordahl KM, Phipps AI, Randolph TW, Tindle HA, Liu S, Tinker LF, Kelsey KT, White E, Bhatti P.

Epigenetics. 2019 Jun 23:1-9. doi: 10.1080/15592294.2019.1631112. [Epub ahead of print]

PMID:
31232174
4.

DEHP Nanodroplets Leached From Polyvinyl Chloride IV Bags Promote Aggregation of IVIG and Activate Complement in Human Serum.

Snell JR, Monticello CR, Her C, Ross EL, Frazer-Abel AA, Carpenter JF, Randolph TW.

J Pharm Sci. 2019 Jun 21. pii: S0022-3549(19)30385-5. doi: 10.1016/j.xphs.2019.06.015. [Epub ahead of print]

PMID:
31229435
5.

Brain connectivity-informed regularization methods for regression.

Karas M, Brzyski D, Dzemidzic M, Goñi J, Kareken DA, Randolph TW, Harezlak J.

Stat Biosci. 2019 Apr;11(1):47-90. doi: 10.1007/s12561-017-9208-x. Epub 2017 Dec 6.

PMID:
31217828
6.

Fecal Microbial Diversity and Structure Are Associated with Diet Quality in the Multiethnic Cohort Adiposity Phenotype Study.

Maskarinec G, Hullar MAJ, Monroe KR, Shepherd JA, Hunt J, Randolph TW, Wilkens LR, Boushey CJ, Le Marchand L, Lim U, Lampe JW.

J Nutr. 2019 Sep 1;149(9):1575-1584. doi: 10.1093/jn/nxz065.

PMID:
31187868
7.

Colonic mucosal and exfoliome transcriptomic profiling and fecal microbiome response to a flaxseed lignan extract intervention in humans.

Lampe JW, Kim E, Levy L, Davidson LA, Goldsby JS, Miles FL, Navarro SL, Randolph TW, Zhao N, Ivanov I, Kaz AM, Damman C, Hockenbery DM, Hullar MAJ, Chapkin RS.

Am J Clin Nutr. 2019 Aug 1;110(2):377-390. doi: 10.1093/ajcn/nqy325.

PMID:
31175806
8.

Comparison of prediction models with radiological semantic features and radiomics in lung cancer diagnosis of the pulmonary nodules: a case-control study.

Wu W, Pierce LA, Zhang Y, Pipavath SNJ, Randolph TW, Lastwika KJ, Lampe PD, Houghton AM, Liu H, Xia L, Kinahan PE.

Eur Radiol. 2019 May 21. doi: 10.1007/s00330-019-06213-9. [Epub ahead of print]

PMID:
31115618
9.

Nanobubbles in Reconstituted Lyophilized Formulations: Interaction With Proteins and Mechanism of Formation.

Snell JR, Kumar NSK, Suryanarayanan R, Randolph TW.

J Pharm Sci. 2019 May 13. pii: S0022-3549(19)30307-7. doi: 10.1016/j.xphs.2019.05.005. [Epub ahead of print]

PMID:
31095959
10.

Rapid Quantification of Protein Particles in High-Concentration Antibody Formulations.

Wu H, Randolph TW.

J Pharm Sci. 2019 Mar;108(3):1110-1116. doi: 10.1016/j.xphs.2018.10.021. Epub 2018 Oct 27.

PMID:
30773198
11.

Conjugation of Emtansine Onto Trastuzumab Promotes Aggregation of the Antibody-Drug Conjugate by Reducing Repulsive Electrostatic Interactions and Increasing Hydrophobic Interactions.

Gandhi AV, Randolph TW, Carpenter JF.

J Pharm Sci. 2019 Jun;108(6):1973-1983. doi: 10.1016/j.xphs.2019.01.029. Epub 2019 Feb 5.

PMID:
30735687
12.

Thermostable Ebola virus vaccine formulations lyophilized in the presence of aluminum hydroxide.

Chisholm CF, Kang TJ, Dong M, Lewis K, Namekar M, Lehrer AT, Randolph TW.

Eur J Pharm Biopharm. 2019 Mar;136:213-220. doi: 10.1016/j.ejpb.2019.01.019. Epub 2019 Jan 28.

PMID:
30703544
13.

Differences in serum biomarkers between combined glucosamine and chondroitin versus celecoxib in a randomized, double-blind trial in osteoarthritis patients.

Navarro SL, Herrero M, Martinez H, Zhang Y, Ladd J, Lo E, Shelley D, Randolph TW, Lampe JW, Lampe PD.

Antiinflamm Antiallergy Agents Med Chem. 2019 Jan 14. doi: 10.2174/1871523018666190115094512. [Epub ahead of print]

PMID:
30648524
14.

Tumor-derived Autoantibodies Identify Malignant Pulmonary Nodules.

Lastwika KJ, Kargl J, Zhang Y, Zhu X, Lo E, Shelley D, Ladd JJ, Wu W, Kinahan P, Pipavath SNJ, Randolph TW, Shipley M, Lampe PD, Houghton AM.

Am J Respir Crit Care Med. 2019 May 15;199(10):1257-1266. doi: 10.1164/rccm.201804-0628OC.

PMID:
30422669
15.

Steric Repulsion Forces Contributed by PEGylation of Interleukin-1 Receptor Antagonist Reduce Gelation and Aggregation at the Silicone Oil-Water Interface.

Sorret LL, Monticello CR, DeWinter MA, Schwartz DK, Randolph TW.

J Pharm Sci. 2019 Jan;108(1):162-172. doi: 10.1016/j.xphs.2018.10.045. Epub 2018 Nov 3.

PMID:
30395835
16.

KERNEL-PENALIZED REGRESSION FOR ANALYSIS OF MICROBIOME DATA.

Randolph TW, Zhao S, Copeland W, Hullar M, Shojaie A.

Ann Appl Stat. 2018 Mar;12(1):540-566. doi: 10.1214/17-AOAS1102. Epub 2018 Mar 9.

17.

Temporal Variability and Stability of the Fecal Microbiome: The Multiethnic Cohort Study.

Fu BC, Randolph TW, Lim U, Monroe KR, Cheng I, Wilkens LR, Le Marchand L, Lampe JW, Hullar MAJ.

Cancer Epidemiol Biomarkers Prev. 2019 Jan;28(1):154-162. doi: 10.1158/1055-9965.EPI-18-0348. Epub 2018 Sep 11.

PMID:
30206059
18.

Urea Improves Stability of Inactivated Polio Vaccine Serotype 3 During Lyophilization and Storage in Dried Formulations.

Qi W, Orgel S, Francon A, Randolph TW, Carpenter JF.

J Pharm Sci. 2018 Aug;107(8):2070-2078. doi: 10.1016/j.xphs.2018.04.019. Epub 2018 Apr 27.

PMID:
29709487
19.

Postproduction Handling and Administration of Protein Pharmaceuticals and Potential Instability Issues.

Nejadnik MR, Randolph TW, Volkin DB, Schöneich C, Carpenter JF, Crommelin DJA, Jiskoot W.

J Pharm Sci. 2018 Aug;107(8):2013-2019. doi: 10.1016/j.xphs.2018.04.005. Epub 2018 Apr 14.

PMID:
29665382
20.

Protein Nanoparticles Promote Microparticle Formation in Intravenous Immunoglobulin Solutions During Freeze-Thawing and Agitation Stresses.

Pardeshi NN, Zhou C, Randolph TW, Carpenter JF.

J Pharm Sci. 2018 Jul;107(7):1852-1857. doi: 10.1016/j.xphs.2018.03.016. Epub 2018 Mar 27.

21.

Genome-Wide DNA Methylation in Prediagnostic Blood and Bladder Cancer Risk in the Women's Health Initiative.

Jordahl KM, Randolph TW, Song X, Sather CL, Tinker LF, Phipps AI, Kelsey KT, White E, Bhatti P.

Cancer Epidemiol Biomarkers Prev. 2018 Jun;27(6):689-695. doi: 10.1158/1055-9965.EPI-17-0951. Epub 2018 Mar 14.

22.

Circulating bile acids in healthy adults respond differently to a dietary pattern characterized by whole grains, legumes and fruits and vegetables compared to a diet high in refined grains and added sugars: A randomized, controlled, crossover feeding study.

Ginos BNR, Navarro SL, Schwarz Y, Gu H, Wang D, Randolph TW, Shojaie A, Hullar MAJ, Lampe PD, Kratz M, Neuhouser ML, Raftery D, Lampe JW.

Metabolism. 2018 Jun;83:197-204. doi: 10.1016/j.metabol.2018.02.006. Epub 2018 Feb 17.

23.

Flow Microscopy Imaging Is Sensitive to Characteristics of Subvisible Particles in Peginesatide Formulations Associated With Severe Adverse Reactions.

Daniels AL, Randolph TW.

J Pharm Sci. 2018 May;107(5):1313-1321. doi: 10.1016/j.xphs.2018.01.015. Epub 2018 Feb 1.

24.

Protein-protein interactions controlling interfacial aggregation of rhIL-1ra are not described by simple colloid models.

Sorret LL, DeWinter MA, Schwartz DK, Randolph TW.

Protein Sci. 2018 Jul;27(7):1191-1204. doi: 10.1002/pro.3382. Epub 2018 Mar 3.

25.

Deep Convolutional Neural Network Analysis of Flow Imaging Microscopy Data to Classify Subvisible Particles in Protein Formulations.

Calderon CP, Daniels AL, Randolph TW.

J Pharm Sci. 2018 Apr;107(4):999-1008. doi: 10.1016/j.xphs.2017.12.008. Epub 2017 Dec 18.

PMID:
29269269
26.

Plasma metabolite abundances are associated with urinary enterolactone excretion in healthy participants on controlled diets.

Miles FL, Navarro SL, Schwarz Y, Gu H, Djukovic D, Randolph TW, Shojaie A, Kratz M, Hullar MAJ, Lampe PD, Neuhouser ML, Raftery D, Lampe JW.

Food Funct. 2017 Sep 20;8(9):3209-3218. doi: 10.1039/c7fo00684e.

27.

Response to Comment to the Editor.

Randolph TW.

Biophys J. 2017 Aug 8;113(3):755-756. doi: 10.1016/j.bpj.2017.06.054. No abstract available.

28.

Oxidative DNA damage during night shift work.

Bhatti P, Mirick DK, Randolph TW, Gong J, Buchanan DT, Zhang JJ, Davis S.

Occup Environ Med. 2017 Sep;74(9):680-683. doi: 10.1136/oemed-2017-104414. Epub 2017 Jun 26.

PMID:
28652381
29.

Adaptive penalties for generalized Tikhonov regularization in statistical regression models with application to spectroscopy data.

Randolph TW, Ding J, Kundu MG, Harezlak J.

J Chemom. 2017 Apr;31(4). pii: e2850. doi: 10.1002/cem.2850. Epub 2016 Oct 28.

30.

Longitudinal Functional Models with Structured Penalties.

Kundu MG, Harezlak J, Randolph TW.

Stat Modelling. 2016 Apr;16(2):114-139. doi: 10.1177/1471082X15626291. Epub 2016 Feb 17.

31.

Immunogenicity of Structurally Perturbed Hen Egg Lysozyme Adsorbed to Silicone Oil Microdroplets in Wild-Type and Transgenic Mouse Models.

Chisholm CF, Soucie KR, Song JS, Strauch P, Torres RM, Carpenter JF, Ragheb JA, Randolph TW.

J Pharm Sci. 2017 Jun;106(6):1519-1527. doi: 10.1016/j.xphs.2017.02.008. Epub 2017 Feb 16.

PMID:
28216023
32.

Microflow Imaging Analyses Reflect Mechanisms of Aggregate Formation: Comparing Protein Particle Data Sets Using the Kullback-Leibler Divergence.

Maddux NR, Daniels AL, Randolph TW.

J Pharm Sci. 2017 May;106(5):1239-1248. doi: 10.1016/j.xphs.2017.01.030. Epub 2017 Feb 1.

PMID:
28159641
33.

Challenges in Predicting Protein-Protein Interactions from Measurements of Molecular Diffusivity.

Sorret LL, DeWinter MA, Schwartz DK, Randolph TW.

Biophys J. 2016 Nov 1;111(9):1831-1842. doi: 10.1016/j.bpj.2016.09.018.

34.

Particle Formation and Aggregation of a Therapeutic Protein in Nanobubble Suspensions.

Snell JR, Zhou C, Carpenter JF, Randolph TW.

J Pharm Sci. 2016 Oct;105(10):3057-3063. doi: 10.1016/j.xphs.2016.06.020. Epub 2016 Jul 31.

35.

Colloidal Instability Fosters Agglomeration of Subvisible Particles Created by Rupture of Gels of a Monoclonal Antibody Formed at Silicone Oil-Water Interfaces.

Mehta SB, Carpenter JF, Randolph TW.

J Pharm Sci. 2016 Aug;105(8):2338-48. doi: 10.1016/j.xphs.2016.06.010. Epub 2016 Jul 13.

PMID:
27422087
36.

Comprehensive site-specific whole genome profiling of stromal and epithelial colonic gene signatures in human sigmoid colon and rectal tissue.

Knight JM, Kim E, Ivanov I, Davidson LA, Goldsby JS, Hullar MA, Randolph TW, Kaz AM, Levy L, Lampe JW, Chapkin RS.

Physiol Genomics. 2016 Sep 1;48(9):651-9. doi: 10.1152/physiolgenomics.00023.2016. Epub 2016 Jul 8.

37.

Pharmacometabonomic Prediction of Busulfan Clearance in Hematopoetic Cell Transplant Recipients.

Navarro SL, Randolph TW, Shireman LM, Raftery D, McCune JS.

J Proteome Res. 2016 Aug 5;15(8):2802-11. doi: 10.1021/acs.jproteome.6b00370. Epub 2016 Jul 20.

38.

Oxidative DNA damage during sleep periods among nightshift workers.

Bhatti P, Mirick DK, Randolph TW, Gong J, Buchanan DT, Zhang JJ, Davis S.

Occup Environ Med. 2016 Aug;73(8):537-44. doi: 10.1136/oemed-2016-103629. Epub 2016 Jun 15.

PMID:
27307003
39.

Reduced Subvisible Particle Formation in Lyophilized Intravenous Immunoglobulin Formulations Containing Polysorbate 20.

Zhou C, Qi W, Lewis EN, Randolph TW, Carpenter JF.

J Pharm Sci. 2016 Aug;105(8):2302-9. doi: 10.1016/j.xphs.2016.05.013. Epub 2016 Jun 9.

PMID:
27290624
40.

Formation of Stable Nanobubbles on Reconstituting Lyophilized Formulations Containing Trehalose.

Zhou C, Cleland D, Snell J, Qi W, Randolph TW, Carpenter JF.

J Pharm Sci. 2016 Jul;105(7):2249-53. doi: 10.1016/j.xphs.2016.04.035. Epub 2016 Jun 8.

PMID:
27287517
41.

Mouse Models for Assessing Protein Immunogenicity: Lessons and Challenges.

Jiskoot W, Kijanka G, Randolph TW, Carpenter JF, Koulov AV, Mahler HC, Joubert MK, Jawa V, Narhi LO.

J Pharm Sci. 2016 May;105(5):1567-1575. doi: 10.1016/j.xphs.2016.02.031. Epub 2016 Apr 1. Review.

42.

Characterization of the gut microbiome in epidemiologic studies: the multiethnic cohort experience.

Fu BC, Randolph TW, Lim U, Monroe KR, Cheng I, Wilkens LR, Le Marchand L, Hullar MA, Lampe JW.

Ann Epidemiol. 2016 May;26(5):373-9. doi: 10.1016/j.annepidem.2016.02.009. Epub 2016 Mar 8. Review.

43.

Silicone Oil Microdroplets Can Induce Antibody Responses Against Recombinant Murine Growth Hormone in Mice.

Chisholm CF, Baker AE, Soucie KR, Torres RM, Carpenter JF, Randolph TW.

J Pharm Sci. 2016 May;105(5):1623-1632. doi: 10.1016/j.xphs.2016.02.019. Epub 2016 Mar 25.

44.

Towards microbiome transplant as a therapy for periodontitis: an exploratory study of periodontitis microbial signature contrasted by oral health, caries and edentulism.

Pozhitkov AE, Leroux BG, Randolph TW, Beikler T, Flemmig TF, Noble PA.

BMC Oral Health. 2015 Oct 14;15:125. doi: 10.1186/s12903-015-0109-4.

45.

Surfactant Effects on Particle Generation in Antibody Formulations in Pre-filled Syringes.

Gerhardt A, Mcumber AC, Nguyen BH, Lewus R, Schwartz DK, Carpenter JF, Randolph TW.

J Pharm Sci. 2015 Dec;104(12):4056-4064. doi: 10.1002/jps.24654. Epub 2015 Sep 28.

46.

The Role of Protein Excipient in Driving Antibody Responses to Erythropoietin.

Christie M, Peritt D, Torres RM, Randolph TW, Carpenter JF.

J Pharm Sci. 2015 Dec;104(12):4041-4055. doi: 10.1002/jps.24639. Epub 2015 Sep 16.

PMID:
26375484
47.

Electrostatic Interactions Influence Protein Adsorption (but Not Desorption) at the Silica-Aqueous Interface.

McUmber AC, Randolph TW, Schwartz DK.

J Phys Chem Lett. 2015 Jul 2;6(13):2583-7. doi: 10.1021/acs.jpclett.5b00933. Epub 2015 Jun 19.

PMID:
26266737
48.

In Vivo Analysis of the Potency of Silicone Oil Microdroplets as Immunological Adjuvants in Protein Formulations.

Chisholm CF, Nguyen BH, Soucie KR, Torres RM, Carpenter JF, Randolph TW.

J Pharm Sci. 2015 Nov;104(11):3681-3690. doi: 10.1002/jps.24573. Epub 2015 Jul 17.

49.

Development of a highly thermostable, adjuvanted human papillomavirus vaccine.

Hassett KJ, Meinerz NM, Semmelmann F, Cousins MC, Garcea RL, Randolph TW.

Eur J Pharm Biopharm. 2015 Aug;94:220-8. doi: 10.1016/j.ejpb.2015.05.009. Epub 2015 May 18.

50.

Molecular trajectories provide signatures of protein clustering and crowding at the oil/water interface.

McUmber AC, Larson NR, Randolph TW, Schwartz DK.

Langmuir. 2015 Jun 2;31(21):5882-90. doi: 10.1021/acs.langmuir.5b00984. Epub 2015 May 19.

PMID:
25950404

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