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1.

The authors reply.

Shein SL, Kong M, Toltzis P, Randolph AG.

Pediatr Crit Care Med. 2019 Aug;20(8):795-796. doi: 10.1097/PCC.0000000000002030. No abstract available.

PMID:
31397821
2.

A Modular Cytokine Analysis Method Reveals Novel Associations With Clinical Phenotypes and Identifies Sets of Co-signaling Cytokines Across Influenza Natural Infection Cohorts and Healthy Controls.

Cohen L, Fiore-Gartland A, Randolph AG, Panoskaltsis-Mortari A, Wong SS, Ralston J, Wood T, Seeds R, Huang QS, Webby RJ, Thomas PG, Hertz T.

Front Immunol. 2019 Jun 18;10:1338. doi: 10.3389/fimmu.2019.01338. eCollection 2019.

3.

Growth and Changing Characteristics of Pediatric Intensive Care 2001-2016.

Horak RV, Griffin JF, Brown AM, Nett ST, Christie LM, Forbes ML, Kubis S, Li S, Singleton MN, Verger JT, Markovitz BP, Burns JP, Chung SA, Randolph AG; Pediatric Acute Lung Injury and Sepsis Investigator’s (PALISI) Network.

Crit Care Med. 2019 Aug;47(8):1135-1142. doi: 10.1097/CCM.0000000000003863.

PMID:
31162205
4.

Evaluation of Mannose Binding Lectin Gene Variants in Pediatric Influenza Virus-Related Critical Illness.

Levy ER, Yip WK, Super M, Ferdinands JM, Mistry AJ, Newhams MM, Zhang Y, Su HC, McLaughlin GE, Sapru A, Loftis LL, Weiss SL, Hall MW, Cvijanovich N, Schwarz A, Tarquinio KM, Mourani PM; PALISI PICFLU Investigators, Randolph AG.

Front Immunol. 2019 May 8;10:1005. doi: 10.3389/fimmu.2019.01005. eCollection 2019.

5.

Acute respiratory distress syndrome.

Matthay MA, Zemans RL, Zimmerman GA, Arabi YM, Beitler JR, Mercat A, Herridge M, Randolph AG, Calfee CS.

Nat Rev Dis Primers. 2019 Mar 14;5(1):18. doi: 10.1038/s41572-019-0069-0. Review.

6.

Cost Implications of Escalating Intravenous Acetaminophen Use in Children.

Bourgeois FT, Graham DA, Kesselheim AS, Randolph AG.

JAMA Pediatr. 2019 May 1;173(5):489-491. doi: 10.1001/jamapediatrics.2019.0101. No abstract available.

PMID:
30855654
7.

Antibiotic Prescription in Young Children With Respiratory Syncytial Virus-Associated Respiratory Failure and Associated Outcomes.

Shein SL, Kong M, McKee B, O'Riordan M, Toltzis P, Randolph AG.

Pediatr Crit Care Med. 2019 Feb;20(2):101-109. doi: 10.1097/PCC.0000000000001839.

PMID:
30720644
8.

Vancomycin Monotherapy May Be Insufficient to Treat Methicillin-resistant Staphylococcus aureus Coinfection in Children With Influenza-related Critical Illness.

Randolph AG, Xu R, Novak T, Newhams MM, Bubeck Wardenburg J, Weiss SL, Sanders RC, Thomas NJ, Hall MW, Tarquinio KM, Cvijanovich N, Gedeit RG, Truemper EJ, Markovitz B, Hartman ME, Ackerman KG, Giuliano JS Jr, Shein SL, Moffitt KL; Pediatric Intensive Care Influenza Investigators from the Pediatric Acute Lung Injury and Sepsis Investigator’s Network.

Clin Infect Dis. 2019 Jan 18;68(3):365-372. doi: 10.1093/cid/ciy495.

9.

Cytokine Profiles of Severe Influenza Virus-Related Complications in Children.

Fiore-Gartland A, Panoskaltsis-Mortari A, Agan AA, Mistry AJ, Thomas PG, Matthay MA; PALISI PICFlu Investigators, Hertz T, Randolph AG.

Front Immunol. 2017 Nov 6;8:1423. doi: 10.3389/fimmu.2017.01423. eCollection 2017.

10.

A Biosignature Predicting Complicated Course in Children Presenting with Septic Shock. Why PERSEVERE?

Randolph AG.

Am J Respir Crit Care Med. 2017 Aug 15;196(4):411-413. doi: 10.1164/rccm.201704-0759ED. No abstract available.

11.

SNP-mediated disruption of CTCF binding at the IFITM3 promoter is associated with risk of severe influenza in humans.

Allen EK, Randolph AG, Bhangale T, Dogra P, Ohlson M, Oshansky CM, Zamora AE, Shannon JP, Finkelstein D, Dressen A, DeVincenzo J, Caniza M, Youngblood B, Rosenberger CM, Thomas PG.

Nat Med. 2017 Aug;23(8):975-983. doi: 10.1038/nm.4370. Epub 2017 Jul 17.

12.

Evaluation of IFITM3 rs12252 Association With Severe Pediatric Influenza Infection.

Randolph AG, Yip WK, Allen EK, Rosenberger CM, Agan AA, Ash SA, Zhang Y, Bhangale TR, Finkelstein D, Cvijanovich NZ, Mourani PM, Hall MW, Su HC, Thomas PG; Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network Pediatric Influenza (PICFLU) Investigators; Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network Pediatric Influenza (PICFLU) Investigators.

J Infect Dis. 2017 Jul 1;216(1):14-21. doi: 10.1093/infdis/jix242.

13.

Why So Few Randomized Trials in Pediatric Critical Care Medicine? Ask the Trialists.

Randolph AG.

Pediatr Crit Care Med. 2017 May;18(5):486-487. doi: 10.1097/PCC.0000000000001156. No abstract available.

PMID:
28475531
14.

Simulation of a Novel Schedule for Intensivist Staffing to Improve Continuity of Patient Care and Reduce Physician Burnout.

Geva A, Landrigan CP, van der Velden MG, Randolph AG.

Crit Care Med. 2017 Jul;45(7):1138-1144. doi: 10.1097/CCM.0000000000002319.

15.

Mannose-Binding Lectin Levels in Critically Ill Children With Severe Infections.

Madsen EC, Levy ER, Madden K, Agan AA, Sullivan RM, Graham DA, Randolph AG.

Pediatr Crit Care Med. 2017 Feb;18(2):103-111. doi: 10.1097/PCC.0000000000001000.

16.

Enterovirus D68 Reemerges Globally as a Severe Pathogen Targeting Children.

Randolph AG.

Pediatr Crit Care Med. 2016 Nov;17(11):1088-1089. No abstract available.

17.

Determinants of red blood cell transfusion in pediatric trauma patients admitted to the intensive care unit.

Roumeliotis N, Ducruet T, Bateman ST, Randolph AG, Lacroix J, Emeriaud G; Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network.

Transfusion. 2017 Jan;57(1):187-194. doi: 10.1111/trf.13857. Epub 2016 Oct 2.

PMID:
27696446
18.

Staphylococcus aureus α-Toxin Response Distinguishes Respiratory Virus-Methicillin-Resistant S. aureus Coinfection in Children.

Yu KO, Randolph AG, Agan AA, Yip WK, Truemper EJ, Weiss SL, Ackerman KG, Schwarz AJ, Giuliano JS Jr, Hall MW, Bubeck Wardenburg J; Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) PICFlu Study Group; PALISI PICFlu Study Group.

J Infect Dis. 2016 Dec 1;214(11):1638-1646. Epub 2016 Sep 20.

19.

High Variability in the Reported Management of Hepatic Veno-Occlusive Disease in Children after Hematopoietic Stem Cell Transplantation.

Skeens MA, McArthur J, Cheifetz IM, Duncan C, Randolph AG, Stanek J, Lehman L, Bajwa R; HSCT subgroup of the Pediatric Acute Lung Injury & Sepsis Investigators (PALISI).

Biol Blood Marrow Transplant. 2016 Oct;22(10):1823-1828. doi: 10.1016/j.bbmt.2016.07.011. Epub 2016 Aug 2.

20.

The Impact of Clinical Trials Conducted by Research Networks in Pediatric Critical Care.

Choong K, Duffett M, Cook DJ, Randolph AG.

Pediatr Crit Care Med. 2016 Sep;17(9):837-44. doi: 10.1097/PCC.0000000000000835. Review.

PMID:
27351267
21.

The authors reply.

Tasker RC, Randolph AG.

Pediatr Crit Care Med. 2016 Jun;17(6):583-4. doi: 10.1097/PCC.0000000000000762. No abstract available.

PMID:
27261660
22.

Pragmatic trials in critically ill children are CATCHing on.

Randolph AG.

Lancet. 2016 Apr 23;387(10029):1697-8. doi: 10.1016/S0140-6736(16)00566-3. Epub 2016 Mar 4. No abstract available.

PMID:
26946924
23.

Optimizing Virus Identification in Critically Ill Children Suspected of Having an Acute Severe Viral Infection.

Randolph AG, Agan AA, Flanagan RF, Meece JK, Fitzgerald JC, Loftis LL, Truemper EJ, Li S, Ferdinands JM; Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) PICFlu Study Group.

Pediatr Crit Care Med. 2016 Apr;17(4):279-86. doi: 10.1097/PCC.0000000000000661.

PMID:
26895562
24.

Severity-of-Illness Scoring in Pediatric Critical Care: Quo Vadis?

Tasker RC, Randolph AG.

Pediatr Crit Care Med. 2016 Jan;17(1):83-5. doi: 10.1097/PCC.0000000000000559. No abstract available.

PMID:
26731320
25.

Pooled Sequencing of Candidate Genes Implicates Rare Variants in the Development of Asthma Following Severe RSV Bronchiolitis in Infancy.

Torgerson DG, Giri T, Druley TE, Zheng J, Huntsman S, Seibold MA, Young AL, Schweiger T, Yin-Declue H, Sajol GD, Schechtman KB, Hernandez RD, Randolph AG, Bacharier LB, Castro M.

PLoS One. 2015 Nov 20;10(11):e0142649. doi: 10.1371/journal.pone.0142649. eCollection 2015.

26.

Anesthesiologist- and System-Related Risk Factors for Risk-Adjusted Pediatric Anesthesia-Related Cardiac Arrest.

Zgleszewski SE, Graham DA, Hickey PR, Brustowicz RM, Odegard KC, Koka R, Seefelder C, Navedo AT, Randolph AG.

Anesth Analg. 2016 Feb;122(2):482-9. doi: 10.1213/ANE.0000000000001059.

PMID:
26554463
27.

Critically Ill Children Have Low Vitamin D-Binding Protein, Influencing Bioavailability of Vitamin D.

Madden K, Feldman HA, Chun RF, Smith EM, Sullivan RM, Agan AA, Keisling SM, Panoskaltsis-Mortari A, Randolph AG.

Ann Am Thorac Soc. 2015 Nov;12(11):1654-61. doi: 10.1513/AnnalsATS.201503-160OC.

28.

Therapeutic Hypothermia in Children.

Geva A, Tasker RC, Randolph AG.

N Engl J Med. 2015 Sep 3;373(10):979. doi: 10.1056/NEJMc1508693. No abstract available.

PMID:
26332559
29.

Pediatric Pulseless Arrest With "Nonshockable" Rhythm: Does Faster Time to Epinephrine Improve Outcome?

Tasker RC, Randolph AG.

JAMA. 2015 Aug 25;314(8):776-7. doi: 10.1001/jama.2015.9527. No abstract available.

PMID:
26305646
30.

Recognizing and managing sepsis: what needs to be done?

Yealy DM, Huang DT, Delaney A, Knight M, Randolph AG, Daniels R, Nutbeam T.

BMC Med. 2015 Apr 27;13:98. doi: 10.1186/s12916-015-0335-2.

31.

The tremendous burden of sepsis on China's youngest children.

Randolph AG.

Pediatr Crit Care Med. 2014 Nov;15(9):896-7. doi: 10.1097/PCC.0000000000000283. No abstract available.

PMID:
25370055
32.

Variability in IRBs regarding parental acceptance of passive consent.

Higgerson RA, Olsho LE, Christie LM, Rehder K, Doksum T, Gedeit R, Giuliano JS Jr, Brennan B, Wendlandt R, Randolph AG; PALISI PICFlu Study Investigators.

Pediatrics. 2014 Aug;134(2):e496-503. doi: 10.1542/peds.2013-4190. Epub 2014 Jul 7.

PMID:
25002659
33.

More consistent site institutional review board (IRB) input-more consistent site IRB output.

Randolph AG, Kornetsky S.

Crit Care Med. 2014 May;42(5):1292-3. doi: 10.1097/CCM.0000000000000203. No abstract available.

PMID:
24736342
34.

Effectiveness of influenza vaccine against life-threatening RT-PCR-confirmed influenza illness in US children, 2010-2012.

Ferdinands JM, Olsho LE, Agan AA, Bhat N, Sullivan RM, Hall M, Mourani PM, Thompson M, Randolph AG; Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network.

J Infect Dis. 2014 Sep 1;210(5):674-83. doi: 10.1093/infdis/jiu185. Epub 2014 Mar 26.

PMID:
24676207
35.

The authors reply.

Goldstein B, Randolph AG.

Pediatr Crit Care Med. 2014 Feb;15(2):183. doi: 10.1097/PCC.0000000000000025. No abstract available.

PMID:
24492192
36.

Vitamin D-binding protein haplotype is associated with hospitalization for RSV bronchiolitis.

Randolph AG, Yip WK, Falkenstein-Hagander K, Weiss ST, Janssen R, Keisling S, Bont L.

Clin Exp Allergy. 2014 Feb;44(2):231-7. doi: 10.1111/cea.12247.

37.
38.

A multinational study of thromboprophylaxis practice in critically ill children.

Faustino EV, Hanson S, Spinella PC, Tucci M, O'Brien SH, Nunez AR, Yung M, Truemper E, Qin L, Li S, Marohn K, Randolph AG; PROphylaxis against ThRombosis prACTice (PROTRACT) Study Investigators of the PALISI BloodNet.

Crit Care Med. 2014 May;42(5):1232-40. doi: 10.1097/CCM.0000000000000147.

39.

Assessment of hemoglobin threshold for packed RBC transfusion in a medical-surgical PICU.

Valentine SL, Lightdale JR, Tran CM, Jiang H, Sloan SR, Kleinman ME, Randolph AG.

Pediatr Crit Care Med. 2014 Feb;15(2):e89-94. doi: 10.1097/PCC.0000000000000033.

PMID:
24335991
40.

Pediatric sepsis: important considerations for diagnosing and managing severe infections in infants, children, and adolescents.

Randolph AG, McCulloh RJ.

Virulence. 2014 Jan 1;5(1):179-89. doi: 10.4161/viru.27045. Epub 2013 Nov 13. Review.

41.

The authors reply.

Carcillo JA, Randolph AG, Hazelzet JA, Dellinger RP.

Crit Care Med. 2013 Oct;41(10):e295. doi: 10.1097/CCM.0b013e3182a51cf0. No abstract available.

PMID:
24060797
42.

Mechanical ventilation strategies in children with acute lung injury: a survey on stated practice pattern*.

Santschi M, Randolph AG, Rimensberger PC, Jouvet P; Pediatric Acute Lung Injury Mechanical Ventilation Investigators; Pediatric Acute Lung Injury and Sepsis Investigators Network; European Society of Pediatric and Neonatal Intensive Care.

Pediatr Crit Care Med. 2013 Sep;14(7):e332-7. doi: 10.1097/PCC.0b013e31828a89a2.

PMID:
23842587
43.

Innate immune function and mortality in critically ill children with influenza: a multicenter study.

Hall MW, Geyer SM, Guo CY, Panoskaltsis-Mortari A, Jouvet P, Ferdinands J, Shay DK, Nateri J, Greathouse K, Sullivan R, Tran T, Keisling S, Randolph AG; Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network PICFlu Study Investigators.

Crit Care Med. 2013 Jan;41(1):224-36. doi: 10.1097/CCM.0b013e318267633c.

44.

Risk factors for mechanical ventilation in U.S. children hospitalized with seasonal influenza and 2009 pandemic influenza A*.

Eriksson CO, Graham DA, Uyeki TM, Randolph AG.

Pediatr Crit Care Med. 2012 Nov;13(6):625-31. doi: 10.1097/PCC.0b013e318260114e.

45.

Vitamin D deficiency in critically ill children.

Madden K, Feldman HA, Smith EM, Gordon CM, Keisling SM, Sullivan RM, Hollis BW, Agan AA, Randolph AG.

Pediatrics. 2012 Sep;130(3):421-8. doi: 10.1542/peds.2011-3328. Epub 2012 Aug 6.

46.

Fluid balance in critically ill children with acute lung injury.

Valentine SL, Sapru A, Higgerson RA, Spinella PC, Flori HR, Graham DA, Brett M, Convery M, Christie LM, Karamessinis L, Randolph AG; Pediatric Acute Lung Injury and Sepsis Investigator's (PALISI) Network; Acute Respiratory Distress Syndrome Clinical Research Network (ARDSNet).

Crit Care Med. 2012 Oct;40(10):2883-9.

47.

A pilot, randomized, controlled clinical trial of lucinactant, a peptide-containing synthetic surfactant, in infants with acute hypoxemic respiratory failure.

Thomas NJ, Guardia CG, Moya FR, Cheifetz IM, Markovitz B, Cruces P, Barton P, Segal R, Simmons P, Randolph AG; PALISI Network.

Pediatr Crit Care Med. 2012 Nov;13(6):646-53. doi: 10.1097/PCC.0b013e3182517bec.

PMID:
22791092
48.

Critical illness from 2009 pandemic influenza A virus and bacterial coinfection in the United States.

Rice TW, Rubinson L, Uyeki TM, Vaughn FL, John BB, Miller RR 3rd, Higgs E, Randolph AG, Smoot BE, Thompson BT; NHLBI ARDS Network.

Crit Care Med. 2012 May;40(5):1487-98. doi: 10.1097/CCM.0b013e3182416f23.

49.

Impact of a conservative red blood cell transfusion strategy in children undergoing hematopoietic stem cell transplantation.

Lightdale JR, Randolph AG, Tran CM, Jiang H, Colon A, Houlahan K, Billet A, Sloan S, Lehmann LE.

Biol Blood Marrow Transplant. 2012 May;18(5):813-7. doi: 10.1016/j.bbmt.2011.10.043. Epub 2011 Nov 11.

50.

Critically ill children during the 2009-2010 influenza pandemic in the United States.

Randolph AG, Vaughn F, Sullivan R, Rubinson L, Thompson BT, Yoon G, Smoot E, Rice TW, Loftis LL, Helfaer M, Doctor A, Paden M, Flori H, Babbitt C, Graciano AL, Gedeit R, Sanders RC, Giuliano JS, Zimmerman J, Uyeki TM; Pediatric Acute Lung Injury and Sepsis Investigator's Network and the National Heart, Lung, and Blood Institute ARDS Clinical Trials Network.

Pediatrics. 2011 Dec;128(6):e1450-8. doi: 10.1542/peds.2011-0774. Epub 2011 Nov 7.

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