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Items: 1 to 50 of 77

1.

Correction: Vascular Endothelial Growth Factor Receptor-2 Couples Cyclo-Oxygenase-2 with Pro-Angiogenic Actions of Leptin on Human Endothelial Cells.

Garonna E, Botham KM, Birdsey GM, Randi AM, Gonzalez-Perez RR, Wheeler-Jones CPD.

PLoS One. 2019 Sep 30;14(9):e0223400. doi: 10.1371/journal.pone.0223400. eCollection 2019.

2.

Extracellular RNA released due to shear stress controls natural bypass growth by mediating mechanotransduction.

Lasch M, Kleinert EC, Meister S, Kumaraswami K, Buchheim JI, Grantzow T, Lautz T, Salpisti S, Fischer S, Troidl K, Fleming I, Randi AM, Sperandio M, Preissner KT, Deindl E.

Blood. 2019 Sep 9. pii: blood.2019001392. doi: 10.1182/blood.2019001392. [Epub ahead of print]

PMID:
31501155
3.

Standardization of methods to quantify and culture endothelial colony-forming cells derived from peripheral blood: Position paper from the International Society on Thrombosis and Haemostasis SSC.

Smadja DM, Melero-Martin JM, Eikenboom J, Bowman M, Sabatier F, Randi AM.

J Thromb Haemost. 2019 Jul;17(7):1190-1194. doi: 10.1111/jth.14462. Epub 2019 May 22. No abstract available.

PMID:
31119878
4.

The heparin binding domain of von Willebrand factor binds to growth factors and promotes angiogenesis in wound healing.

Ishihara J, Ishihara A, Starke RD, Peghaire CR, Smith KE, McKinnon TAJ, Tabata Y, Sasaki K, White MJV, Fukunaga K, Laffan MA, Lutolf MP, Randi AM, Hubbell JA.

Blood. 2019 Jun 13;133(24):2559-2569. doi: 10.1182/blood.2019000510. Epub 2019 Apr 11.

PMID:
30975637
5.

The Transcription Factor ERG Regulates Super-Enhancers Associated With an Endothelial-Specific Gene Expression Program.

Kalna V, Yang Y, Peghaire CR, Frudd K, Hannah R, Shah AV, Osuna Almagro L, Boyle JJ, Göttgens B, Ferrer J, Randi AM, Birdsey GM.

Circ Res. 2019 Apr 26;124(9):1337-1349. doi: 10.1161/CIRCRESAHA.118.313788.

6.

Neuropilin-1 Controls Endothelial Homeostasis by Regulating Mitochondrial Function and Iron-Dependent Oxidative Stress.

Issitt T, Bosseboeuf E, De Winter N, Dufton N, Gestri G, Senatore V, Chikh A, Randi AM, Raimondi C.

iScience. 2019 Jan 25;11:205-223. doi: 10.1016/j.isci.2018.12.005. Epub 2018 Dec 11.

7.

Recent Advances in Endothelial Colony Forming Cells Toward Their Use in Clinical Translation.

Paschalaki KE, Randi AM.

Front Med (Lausanne). 2018 Oct 23;5:295. doi: 10.3389/fmed.2018.00295. eCollection 2018. Review.

8.

von Willebrand factor regulation of blood vessel formation.

Randi AM, Smith KE, Castaman G.

Blood. 2018 Jul 12;132(2):132-140. doi: 10.1182/blood-2018-01-769018. Epub 2018 Jun 4. Review.

9.

Consensus guidelines for the use and interpretation of angiogenesis assays.

Nowak-Sliwinska P, Alitalo K, Allen E, Anisimov A, Aplin AC, Auerbach R, Augustin HG, Bates DO, van Beijnum JR, Bender RHF, Bergers G, Bikfalvi A, Bischoff J, Böck BC, Brooks PC, Bussolino F, Cakir B, Carmeliet P, Castranova D, Cimpean AM, Cleaver O, Coukos G, Davis GE, De Palma M, Dimberg A, Dings RPM, Djonov V, Dudley AC, Dufton NP, Fendt SM, Ferrara N, Fruttiger M, Fukumura D, Ghesquière B, Gong Y, Griffin RJ, Harris AL, Hughes CCW, Hultgren NW, Iruela-Arispe ML, Irving M, Jain RK, Kalluri R, Kalucka J, Kerbel RS, Kitajewski J, Klaassen I, Kleinmann HK, Koolwijk P, Kuczynski E, Kwak BR, Marien K, Melero-Martin JM, Munn LL, Nicosia RF, Noel A, Nurro J, Olsson AK, Petrova TV, Pietras K, Pili R, Pollard JW, Post MJ, Quax PHA, Rabinovich GA, Raica M, Randi AM, Ribatti D, Ruegg C, Schlingemann RO, Schulte-Merker S, Smith LEH, Song JW, Stacker SA, Stalin J, Stratman AN, Van de Velde M, van Hinsbergh VWM, Vermeulen PB, Waltenberger J, Weinstein BM, Xin H, Yetkin-Arik B, Yla-Herttuala S, Yoder MC, Griffioen AW.

Angiogenesis. 2018 Aug;21(3):425-532. doi: 10.1007/s10456-018-9613-x. Review.

10.

GPR182 is a novel marker for sinusoidal endothelial differentiation with distinct GPCR signaling activity in vitro.

Schmid CD, Schledzewski K, Mogler C, Waldburger N, Kalna V, Marx A, Randi AM, Géraud C, Goerdt S, Koch PS.

Biochem Biophys Res Commun. 2018 Feb 26;497(1):32-38. doi: 10.1016/j.bbrc.2018.01.185. Epub 2018 Feb 1.

11.

Dynamic regulation of canonical TGFβ signalling by endothelial transcription factor ERG protects from liver fibrogenesis.

Dufton NP, Peghaire CR, Osuna-Almagro L, Raimondi C, Kalna V, Chuahan A, Webb G, Yang Y, Birdsey GM, Lalor P, Mason JC, Adams DH, Randi AM.

Nat Commun. 2017 Oct 12;8(1):895. doi: 10.1038/s41467-017-01169-0.

12.

Investigation of cardiac fibroblasts using myocardial slices.

Perbellini F, Watson SA, Scigliano M, Alayoubi S, Tkach S, Bardi I, Quaife N, Kane C, Dufton NP, Simon A, Sikkel MB, Faggian G, Randi AM, Gorelik J, Harding SE, Terracciano CM.

Cardiovasc Res. 2018 Jan 1;114(1):77-89. doi: 10.1093/cvr/cvx152.

13.

Downregulation of MicroRNA-126 Augments DNA Damage Response in Cigarette Smokers and Patients with Chronic Obstructive Pulmonary Disease.

Paschalaki KE, Zampetaki A, Baker JR, Birrell MA, Starke RD, Belvisi MG, Donnelly LE, Mayr M, Randi AM, Barnes PJ.

Am J Respir Crit Care Med. 2018 Mar 1;197(5):665-668. doi: 10.1164/rccm.201706-1304LE. No abstract available.

14.

The endothelial transcription factor ERG mediates Angiopoietin-1-dependent control of Notch signalling and vascular stability.

Shah AV, Birdsey GM, Peghaire C, Pitulescu ME, Dufton NP, Yang Y, Weinberg I, Osuna Almagro L, Payne L, Mason JC, Gerhardt H, Adams RH, Randi AM.

Nat Commun. 2017 Jul 11;8:16002. doi: 10.1038/ncomms16002.

15.

Angiogenesis and the ADAMTS13-VWF balance.

Randi AM.

Blood. 2017 Jul 6;130(1):1-2. doi: 10.1182/blood-2017-05-781260. No abstract available.

PMID:
28684444
16.

Endothelial Progenitors: A Consensus Statement on Nomenclature.

Medina RJ, Barber CL, Sabatier F, Dignat-George F, Melero-Martin JM, Khosrotehrani K, Ohneda O, Randi AM, Chan JKY, Yamaguchi T, Van Hinsbergh VWM, Yoder MC, Stitt AW.

Stem Cells Transl Med. 2017 May;6(5):1316-1320. doi: 10.1002/sctm.16-0360. Epub 2017 Mar 10. Review.

17.

Von Willebrand factor and angiogenesis: basic and applied issues.

Randi AM, Laffan MA.

J Thromb Haemost. 2017 Jan;15(1):13-20. doi: 10.1111/jth.13551. Review.

18.

Vascular biology: New mechanisms and pathways.

Dulak J, Alexander MY, Randi AM.

Vascul Pharmacol. 2016 Nov;86:1-2. doi: 10.1016/j.vph.2016.10.005. Epub 2016 Oct 14. No abstract available.

PMID:
27746374
19.

Molecular dynamics studies on the DNA-binding process of ERG.

Beuerle MG, Dufton NP, Randi AM, Gould IR.

Mol Biosyst. 2016 Nov 15;12(12):3600-3610.

20.

Identification of cyclins A1, E1 and vimentin as downstream targets of heme oxygenase-1 in vascular endothelial growth factor-mediated angiogenesis.

Bauer A, Mylroie H, Thornton CC, Calay D, Birdsey GM, Kiprianos AP, Wilson GK, Soares MP, Yin X, Mayr M, Randi AM, Mason JC.

Sci Rep. 2016 Jul 8;6:29417. doi: 10.1038/srep29417.

21.

Regulation of endothelial homeostasis, vascular development and angiogenesis by the transcription factor ERG.

Shah AV, Birdsey GM, Randi AM.

Vascul Pharmacol. 2016 Nov;86:3-13. doi: 10.1016/j.vph.2016.05.003. Epub 2016 May 18. Review.

22.

Endothelial dysfunction in von Willebrand disease: angiogenesis and angiodysplasia.

Randi AM.

Thromb Res. 2016 May;141 Suppl 2:S55-8. doi: 10.1016/S0049-3848(16)30366-8. Review.

PMID:
27207426
23.

Endothelial Dimethylarginine Dimethylaminohydrolase 1 Is an Important Regulator of Angiogenesis but Does Not Regulate Vascular Reactivity or Hemodynamic Homeostasis.

Dowsett L, Piper S, Slaviero A, Dufton N, Wang Z, Boruc O, Delahaye M, Colman L, Kalk E, Tomlinson J, Birdsey G, Randi AM, Leiper J.

Circulation. 2015 Jun 23;131(25):2217-25. doi: 10.1161/CIRCULATIONAHA.114.015064. Epub 2015 Apr 24.

PMID:
25910799
24.

PKCε-CREB-Nrf2 signalling induces HO-1 in the vascular endothelium and enhances resistance to inflammation and apoptosis.

Mylroie H, Dumont O, Bauer A, Thornton CC, Mackey J, Calay D, Hamdulay SS, Choo JR, Boyle JJ, Samarel AM, Randi AM, Evans PC, Mason JC.

Cardiovasc Res. 2015 Jun 1;106(3):509-19. doi: 10.1093/cvr/cvv131. Epub 2015 Apr 16.

25.

ZO-1 controls endothelial adherens junctions, cell-cell tension, angiogenesis, and barrier formation.

Tornavaca O, Chia M, Dufton N, Almagro LO, Conway DE, Randi AM, Schwartz MA, Matter K, Balda MS.

J Cell Biol. 2015 Mar 16;208(6):821-38. doi: 10.1083/jcb.201404140. Epub 2015 Mar 9.

26.

An autologous endothelial cell:peripheral blood mononuclear cell assay that detects cytokine storm responses to biologics.

Reed DM, Paschalaki KE, Starke RD, Mohamed NA, Sharp G, Fox B, Eastwood D, Bristow A, Ball C, Vessillier S, Hansel TT, Thorpe SJ, Randi AM, Stebbings R, Mitchell JA.

FASEB J. 2015 Jun;29(6):2595-602. doi: 10.1096/fj.14-268144. Epub 2015 Mar 6.

PMID:
25746794
27.

The endothelial transcription factor ERG promotes vascular stability and growth through Wnt/β-catenin signaling.

Birdsey GM, Shah AV, Dufton N, Reynolds LE, Osuna Almagro L, Yang Y, Aspalter IM, Khan ST, Mason JC, Dejana E, Göttgens B, Hodivala-Dilke K, Gerhardt H, Adams RH, Randi AM.

Dev Cell. 2015 Jan 12;32(1):82-96. doi: 10.1016/j.devcel.2014.11.016.

28.

Methotrexate-mediated activation of an AMPK-CREB-dependent pathway: a novel mechanism for vascular protection in chronic systemic inflammation.

Thornton CC, Al-Rashed F, Calay D, Birdsey GM, Bauer A, Mylroie H, Morley BJ, Randi AM, Haskard DO, Boyle JJ, Mason JC.

Ann Rheum Dis. 2016 Feb;75(2):439-48. doi: 10.1136/annrheumdis-2014-206305. Epub 2015 Jan 9.

29.

The epiphytic fern Elaphoglossum luridum (Fée) Christ. (Dryopteridaceae) from Central and South America: morphological and physiological responses to water stress.

Minardi BD, Voytena AP, Santos M, Randi AM.

ScientificWorldJournal. 2014;2014:817892. doi: 10.1155/2014/817892. Epub 2014 Oct 20.

30.

Synergistic therapeutic vascular cytoprotection against complement-mediated injury induced via a PKCα-, AMPK-, and CREB-dependent pathway.

Hamdulay SS, Wang B, Calay D, Kiprianos AP, Cole J, Dumont O, Dryden N, Randi AM, Thornton CC, Al-Rashed F, Hoong C, Shamsi A, Liu Z, Holla VR, Boyle JJ, Haskard DO, Mason JC.

J Immunol. 2014 May 1;192(9):4316-27. doi: 10.4049/jimmunol.1301702. Epub 2014 Mar 26.

31.

ICAM-2 regulates vascular permeability and N-cadherin localization through ezrin-radixin-moesin (ERM) proteins and Rac-1 signalling.

Amsellem V, Dryden NH, Martinelli R, Gavins F, Almagro LO, Birdsey GM, Haskard DO, Mason JC, Turowski P, Randi AM.

Cell Commun Signal. 2014 Mar 4;12:12. doi: 10.1186/1478-811X-12-12.

32.

Von Willebrand factor, angiodysplasia and angiogenesis.

Randi AM, Laffan MA, Starke RD.

Mediterr J Hematol Infect Dis. 2013 Sep 2;5(1):e2013060. doi: 10.4084/MJHID.2013.060. Review.

33.

Dysfunction of endothelial progenitor cells from smokers and chronic obstructive pulmonary disease patients due to increased DNA damage and senescence.

Paschalaki KE, Starke RD, Hu Y, Mercado N, Margariti A, Gorgoulis VG, Randi AM, Barnes PJ.

Stem Cells. 2013 Dec;31(12):2813-26. doi: 10.1002/stem.1488.

34.

FAK-heterozygous mice display enhanced tumour angiogenesis.

Kostourou V, Lechertier T, Reynolds LE, Lees DM, Baker M, Jones DT, Tavora B, Ramjaun AR, Birdsey GM, Robinson SD, Parsons M, Randi AM, Hart IR, Hodivala-Dilke K.

Nat Commun. 2013;4:2020. doi: 10.1038/ncomms3020.

35.

Cellular and molecular basis of von Willebrand disease: studies on blood outgrowth endothelial cells.

Starke RD, Paschalaki KE, Dyer CE, Harrison-Lavoie KJ, Cutler JA, McKinnon TA, Millar CM, Cutler DF, Laffan MA, Randi AM.

Blood. 2013 Apr 4;121(14):2773-84. doi: 10.1182/blood-2012-06-435727. Epub 2013 Jan 25.

36.

Cytoprotective signaling and gene expression in endothelial cells and macrophages-lessons for atherosclerosis.

Haskard DO, Boyle JJ, Evans PC, Mason JC, Randi AM.

Microcirculation. 2013 Apr;20(3):203-16. doi: 10.1111/micc.12020. Review.

PMID:
23121167
37.

Protein kinase Cε activity induces anti-inflammatory and anti-apoptotic genes via an ERK1/2- and NF-κB-dependent pathway to enhance vascular protection.

Dumont O, Mylroie H, Bauer A, Calay D, Sperone A, Thornton C, Hamdulay SS, Ali N, Boyle JJ, Choo JR, Samarel AM, Haskard DO, Randi AM, Evans PC, Mason JC.

Biochem J. 2012 Oct 15;447(2):193-204.

PMID:
22849349
38.

The transcription factor Erg controls endothelial cell quiescence by repressing activity of nuclear factor (NF)-κB p65.

Dryden NH, Sperone A, Martin-Almedina S, Hannah RL, Birdsey GM, Khan ST, Layhadi JA, Mason JC, Haskard DO, Göttgens B, Randi AM.

J Biol Chem. 2012 Apr 6;287(15):12331-42. doi: 10.1074/jbc.M112.346791. Epub 2012 Feb 15.

39.

The transcription factor Erg regulates expression of histone deacetylase 6 and multiple pathways involved in endothelial cell migration and angiogenesis.

Birdsey GM, Dryden NH, Shah AV, Hannah R, Hall MD, Haskard DO, Parsons M, Mason JC, Zvelebil M, Gottgens B, Ridley AJ, Randi AM.

Blood. 2012 Jan 19;119(3):894-903. doi: 10.1182/blood-2011-04-350025. Epub 2011 Nov 23.

PMID:
22117042
40.

Vascular endothelial growth factor receptor-2 couples cyclo-oxygenase-2 with pro-angiogenic actions of leptin on human endothelial cells.

Garonna E, Botham KM, Birdsey GM, Randi AM, Gonzalez-Perez RR, Wheeler-Jones CP.

PLoS One. 2011 Apr 18;6(4):e18823. doi: 10.1371/journal.pone.0018823. Erratum in: PLoS One. 2019 Sep 30;14(9):e0223400.

41.

Endothelial von Willebrand factor regulates angiogenesis.

Starke RD, Ferraro F, Paschalaki KE, Dryden NH, McKinnon TA, Sutton RE, Payne EM, Haskard DO, Hughes AD, Cutler DF, Laffan MA, Randi AM.

Blood. 2011 Jan 20;117(3):1071-80. doi: 10.1182/blood-2010-01-264507. Epub 2010 Nov 3.

42.

The transcription factor Erg inhibits vascular inflammation by repressing NF-kappaB activation and proinflammatory gene expression in endothelial cells.

Sperone A, Dryden NH, Birdsey GM, Madden L, Johns M, Evans PC, Mason JC, Haskard DO, Boyle JJ, Paleolog EM, Randi AM.

Arterioscler Thromb Vasc Biol. 2011 Jan;31(1):142-50. doi: 10.1161/ATVBAHA.110.216473. Epub 2010 Oct 21.

PMID:
20966395
43.

Regulation of angiogenesis by ETS transcription factors.

Randi AM, Sperone A, Dryden NH, Birdsey GM.

Biochem Soc Trans. 2009 Dec;37(Pt 6):1248-53. doi: 10.1042/BST0371248. Review.

PMID:
19909256
44.

PPARdelta and PGC1alpha act cooperatively to induce haem oxygenase-1 and enhance vascular endothelial cell resistance to stress.

Ali F, Ali NS, Bauer A, Boyle JJ, Hamdulay SS, Haskard DO, Randi AM, Mason JC.

Cardiovasc Res. 2010 Mar 1;85(4):701-10. doi: 10.1093/cvr/cvp365. Epub 2009 Nov 10.

PMID:
19903700
45.

Myeloid cell-induced angiogenesis: a sticky business.

Randi AM, Bussolati B.

Blood. 2009 Jun 25;113(26):6508-10. doi: 10.1182/blood-2009-04-213173. No abstract available.

PMID:
19556435
46.

Transcription factor Erg regulates angiogenesis and endothelial apoptosis through VE-cadherin.

Birdsey GM, Dryden NH, Amsellem V, Gebhardt F, Sahnan K, Haskard DO, Dejana E, Mason JC, Randi AM.

Blood. 2008 Apr 1;111(7):3498-506. doi: 10.1182/blood-2007-08-105346. Epub 2008 Jan 14.

47.

Statin-mediated cytoprotection of human vascular endothelial cells: a role for Kruppel-like factor 2-dependent induction of heme oxygenase-1.

Ali F, Hamdulay SS, Kinderlerer AR, Boyle JJ, Lidington EA, Yamaguchi T, Soares MP, Haskard DO, Randi AM, Mason JC.

J Thromb Haemost. 2007 Dec;5(12):2537-46. Epub 2007 Oct 8.

48.

Foxs and Ets in the transcriptional regulation of endothelial cell differentiation and angiogenesis.

Dejana E, Taddei A, Randi AM.

Biochim Biophys Acta. 2007 Jun;1775(2):298-312. Epub 2007 May 18. Review.

PMID:
17572301
49.

Aprotinin inhibits proinflammatory activation of endothelial cells by thrombin through the protease-activated receptor 1.

Day JR, Taylor KM, Lidington EA, Mason JC, Haskard DO, Randi AM, Landis RC.

J Thorac Cardiovasc Surg. 2006 Jan;131(1):21-7.

50.

Endothelial intercellular adhesion molecule (ICAM)-2 regulates angiogenesis.

Huang MT, Mason JC, Birdsey GM, Amsellem V, Gerwin N, Haskard DO, Ridley AJ, Randi AM.

Blood. 2005 Sep 1;106(5):1636-43. Epub 2005 May 26.

PMID:
15920013

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