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Items: 1 to 50 of 110


Nicotine-Use/Smoking Is Associated with the Efficacy of Naltrexone in the Treatment of Alcohol Dependence.

Anton RF, Latham PK, Voronin KE, Randall PK, Book SW, Hoffman M, Schacht JP.

Alcohol Clin Exp Res. 2018 Apr;42(4):751-760. doi: 10.1111/acer.13601. Epub 2018 Feb 12.


Dopaminergic Genetic Variation Influences Aripiprazole Effects on Alcohol Self-Administration and the Neural Response to Alcohol Cues in a Randomized Trial.

Schacht JP, Voronin KE, Randall PK, Anton RF.

Neuropsychopharmacology. 2018 May;43(6):1247-1256. doi: 10.1038/npp.2017.298. Epub 2017 Dec 6.


Predictors of Naltrexone Response in a Randomized Trial: Reward-Related Brain Activation, OPRM1 Genotype, and Smoking Status.

Schacht JP, Randall PK, Latham PK, Voronin KE, Book SW, Myrick H, Anton RF.

Neuropsychopharmacology. 2017 Dec;42(13):2654. doi: 10.1038/npp.2017.185.


Aripiprazole Suppression of Drinking in a Clinical Laboratory Paradigm: Influence of Impulsivity and Self-Control.

Anton RF, Schacht JP, Voronin KE, Randall PK.

Alcohol Clin Exp Res. 2017 Jul;41(7):1370-1380. doi: 10.1111/acer.13417. Epub 2017 Jun 5.


Predictors of Naltrexone Response in a Randomized Trial: Reward-Related Brain Activation, OPRM1 Genotype, and Smoking Status.

Schacht JP, Randall PK, Latham PK, Voronin KE, Book SW, Myrick H, Anton RF.

Neuropsychopharmacology. 2017 Dec;42(13):2640-2653. doi: 10.1038/npp.2017.74. Epub 2017 Apr 14. Erratum in: Neuropsychopharmacology. 2017 Dec;42(13):2654.


Orbitofrontal Neuroadaptations and Cross-Species Synaptic Biomarkers in Heavy-Drinking Macaques.

Nimitvilai S, Uys JD, Woodward JJ, Randall PK, Ball LE, Williams RW, Jones BC, Lu L, Grant KA, Mulholland PJ.

J Neurosci. 2017 Mar 29;37(13):3646-3660. doi: 10.1523/JNEUROSCI.0133-17.2017. Epub 2017 Mar 7.


Differential potassium channel gene regulation in BXD mice reveals novel targets for pharmacogenetic therapies to reduce heavy alcohol drinking.

Rinker JA, Fulmer DB, Trantham-Davidson H, Smith ML, Williams RW, Lopez MF, Randall PK, Chandler LJ, Miles MF, Becker HC, Mulholland PJ.

Alcohol. 2017 Feb;58:33-45. doi: 10.1016/j.alcohol.2016.05.007. Epub 2016 Jun 27.


Phenotype-dependent inhibition of glutamatergic transmission on nucleus accumbens medium spiny neurons by the abused inhalant toluene.

Beckley JT, Randall PK, Smith RJ, Hughes BA, Kalivas PW, Woodward JJ.

Addict Biol. 2016 May;21(3):530-46. doi: 10.1111/adb.12235. Epub 2015 Mar 6.


KCNN Genes that Encode Small-Conductance Ca2+-Activated K+ Channels Influence Alcohol and Drug Addiction.

Padula AE, Griffin WC 3rd, Lopez MF, Nimitvilai S, Cannady R, McGuier NS, Chesler EJ, Miles MF, Williams RW, Randall PK, Woodward JJ, Becker HC, Mulholland PJ.

Neuropsychopharmacology. 2015 Jul;40(8):1928-39. doi: 10.1038/npp.2015.42. Epub 2015 Feb 9.


The potential utility of drinking motive questions to screen at-risk drinking in socially anxious patients.

Miller PM, Book SW, Thomas S, Smith JP, Randall PK, Randall CL.

J Subst Use. 2014 Jun 1;19(3):225-228.


Adolescent alcohol exposure reduces behavioral flexibility, promotes disinhibition, and increases resistance to extinction of ethanol self-administration in adulthood.

Gass JT, Glen WB Jr, McGonigal JT, Trantham-Davidson H, Lopez MF, Randall PK, Yaxley R, Floresco SB, Chandler LJ.

Neuropsychopharmacology. 2014 Oct;39(11):2570-83. doi: 10.1038/npp.2014.109. Epub 2014 May 13.


Varenicline effects on drinking, craving and neural reward processing among non-treatment-seeking alcohol-dependent individuals.

Schacht JP, Anton RF, Randall PK, Li X, Henderson S, Myrick H.

Psychopharmacology (Berl). 2014 Sep;231(18):3799-807. doi: 10.1007/s00213-014-3518-1. Epub 2014 Mar 20.


A double-blind placebo-controlled trial of N-acetylcysteine in the treatment of cocaine dependence.

LaRowe SD, Kalivas PW, Nicholas JS, Randall PK, Mardikian PN, Malcolm RJ.

Am J Addict. 2013 Sep-Oct;22(5):443-52. doi: 10.1111/j.1521-0391.2013.12034.x. Epub 2013 May 15.


Modeling longitudinal drinking data in clinical trials: an application to the COMBINE study.

DeSantis SM, Bandyopadhyay D, Baker NL, Randall PK, Anton RF, Prisciandaro JJ.

Drug Alcohol Depend. 2013 Sep 1;132(1-2):244-50. doi: 10.1016/j.drugalcdep.2013.02.013. Epub 2013 Apr 6.


Treating individuals with social anxiety disorder and at-risk drinking: phasing in a brief alcohol intervention following paroxetine.

Book SW, Thomas SE, Smith JP, Randall PK, Kushner MG, Bernstein GA, Specker SM, Miller PM, Randall CL.

J Anxiety Disord. 2013 Mar;27(2):252-8. doi: 10.1016/j.janxdis.2013.02.008. Epub 2013 Mar 4.


Effects of a GABA-ergic medication combination and initial alcohol withdrawal severity on cue-elicited brain activation among treatment-seeking alcoholics.

Schacht JP, Anton RF, Randall PK, Li X, Henderson S, Myrick H.

Psychopharmacology (Berl). 2013 Jun;227(4):627-37. doi: 10.1007/s00213-013-2996-x. Epub 2013 Feb 7.


Interacting effects of naltrexone and OPRM1 and DAT1 variation on the neural response to alcohol cues.

Schacht JP, Anton RF, Voronin KE, Randall PK, Li X, Henderson S, Myrick H.

Neuropsychopharmacology. 2013 Feb;38(3):414-22. doi: 10.1038/npp.2012.195. Epub 2012 Oct 3.


Hair ethyl glucuronide is highly sensitive and specific for detecting moderate-to-heavy drinking in patients with liver disease.

Stewart SH, Koch DG, Willner IR, Randall PK, Reuben A.

Alcohol Alcohol. 2013 Jan-Feb;48(1):83-7. doi: 10.1093/alcalc/ags109. Epub 2012 Sep 25.


Interactive effects of methylphenidate and alcohol on discrimination, conditioned place preference and motor coordination in C57BL/6J mice.

Griffin WC 3rd, McGovern RW, Bell GH, Randall PK, Middaugh LD, Patrick KS.

Psychopharmacology (Berl). 2013 Feb;225(3):613-25. doi: 10.1007/s00213-012-2849-z. Epub 2012 Sep 7.


Naltrexone modification of drinking effects in a subacute treatment and bar-lab paradigm: influence of OPRM1 and dopamine transporter (SLC6A3) genes.

Anton RF, Voronin KK, Randall PK, Myrick H, Tiffany A.

Alcohol Clin Exp Res. 2012 Nov;36(11):2000-7. doi: 10.1111/j.1530-0277.2012.01807.x. Epub 2012 May 2.


NR2B-deficient mice are more sensitive to the locomotor stimulant and depressant effects of ethanol.

Badanich KA, Doremus-Fitzwater TL, Mulholland PJ, Randall PK, Delpire E, Becker HC.

Genes Brain Behav. 2011 Oct;10(7):805-816. doi: 10.1111/j.1601-183X.2011.00720.x. Epub 2011 Aug 15.


Neurocognitive performance, alcohol withdrawal, and effects of a combination of flumazenil and gabapentin in alcohol dependence.

Schacht JP, Randall PK, Waid LR, Baros AM, Latham PK, Wright TM, Myrick H, Anton RF.

Alcohol Clin Exp Res. 2011 Nov;35(11):2030-8. doi: 10.1111/j.1530-0277.2011.01554.x. Epub 2011 Jun 1.


Gabapentin combined with naltrexone for the treatment of alcohol dependence.

Anton RF, Myrick H, Wright TM, Latham PK, Baros AM, Waid LR, Randall PK.

Am J Psychiatry. 2011 Jul;168(7):709-17. doi: 10.1176/appi.ajp.2011.10101436. Epub 2011 Mar 31.


12-Step Therapy and Women with and without Social Phobia: A Study of the Effectiveness of 12-Step Therapy to Facilitate AA Engagement.

Tonigan JS, Book SW, Pagano ME, Randall PK, Smith JP, Randall CL.

Alcohol Treat Q. 2010 Apr 1;28(2):151-162.


Stability of fMRI striatal response to alcohol cues: a hierarchical linear modeling approach.

Schacht JP, Anton RF, Randall PK, Li X, Henderson S, Myrick H.

Neuroimage. 2011 May 1;56(1):61-8. doi: 10.1016/j.neuroimage.2011.02.004. Epub 2011 Feb 18.


An acute psychosocial stressor increases drinking in non-treatment-seeking alcoholics.

Thomas SE, Bacon AK, Randall PK, Brady KT, See RE.

Psychopharmacology (Berl). 2011 Nov;218(1):19-28. doi: 10.1007/s00213-010-2163-6. Epub 2011 Jan 28.


An acute psychosocial stressor does not potentiate alcohol cue reactivity in non-treatment-seeking alcoholics.

Thomas SE, Randall PK, Brady K, See RE, Drobes DJ.

Alcohol Clin Exp Res. 2011 Mar;35(3):464-73. doi: 10.1111/j.1530-0277.2010.01363.x. Epub 2010 Dec 8.


Effects of brain-derived neurotrophic factor on dopaminergic function and motor behavior during aging.

Boger HA, Mannangatti P, Samuvel DJ, Saylor AJ, Bender TS, McGinty JF, Fortress AM, Zaman V, Huang P, Middaugh LD, Randall PK, Jayanthi LD, Rohrer B, Helke KL, Granholm AC, Ramamoorthy S.

Genes Brain Behav. 2011 Mar;10(2):186-98. doi: 10.1111/j.1601-183X.2010.00654.x. Epub 2010 Oct 19.


Gender differences in alcohol treatment: an analysis of outcome from the COMBINE study.

Greenfield SF, Pettinati HM, O'Malley S, Randall PK, Randall CL.

Alcohol Clin Exp Res. 2010 Oct;34(10):1803-12. doi: 10.1111/j.1530-0277.2010.01267.x. Epub 2010 Jul 20.


The effect of aripiprazole on cue-induced brain activation and drinking parameters in alcoholics.

Myrick H, Li X, Randall PK, Henderson S, Voronin K, Anton RF.

J Clin Psychopharmacol. 2010 Aug;30(4):365-72. doi: 10.1097/JCP.0b013e3181e75cff.


Phosphatidylethanol and alcohol consumption in reproductive age women.

Stewart SH, Law TL, Randall PK, Newman R.

Alcohol Clin Exp Res. 2010 Mar 1;34(3):488-92. doi: 10.1111/j.1530-0277.2009.01113.x. Epub 2009 Dec 17.


Efficacy of a combination of flumazenil and gabapentin in the treatment of alcohol dependence: relationship to alcohol withdrawal symptoms.

Anton RF, Myrick H, Baros AM, Latham PK, Randall PK, Wright TM, Stewart SH, Waid R, Malcolm R.

J Clin Psychopharmacol. 2009 Aug;29(4):334-42. doi: 10.1097/JCP.0b013e3181aba6a4.


Preliminary evaluation of phosphatidylethanol and alcohol consumption in patients with liver disease and hypertension.

Stewart SH, Reuben A, Brzezinski WA, Koch DG, Basile J, Randall PK, Miller PM.

Alcohol Alcohol. 2009 Sep-Oct;44(5):464-7. doi: 10.1093/alcalc/agp039. Epub 2009 Jun 17.


A double-blind trial of gabapentin versus lorazepam in the treatment of alcohol withdrawal.

Myrick H, Malcolm R, Randall PK, Boyle E, Anton RF, Becker HC, Randall CL.

Alcohol Clin Exp Res. 2009 Sep;33(9):1582-8. doi: 10.1111/j.1530-0277.2009.00986.x. Epub 2009 May 26.


Treatment of social anxiety with paroxetine: mediation of changes in anxiety and depression symptoms.

Dempsey JP, Randall PK, Thomas SE, Book SW, Carrigan MH.

Compr Psychiatry. 2009 Mar-Apr;50(2):135-41. doi: 10.1016/j.comppsych.2008.06.009. Epub 2008 Aug 23.


Social anxiety impacts willingness to participate in addiction treatment.

Book SW, Thomas SE, Dempsey JP, Randall PK, Randall CL.

Addict Behav. 2009 May;34(5):474-6. doi: 10.1016/j.addbeh.2008.12.011. Epub 2009 Jan 7.


COMT genotype influences the effect of alcohol on blood pressure: results from the COMBINE study.

Stewart SH, Oroszi G, Randall PK, Anton RF.

Am J Hypertens. 2009 Jan;22(1):87-91. doi: 10.1038/ajh.2008.321. Epub 2008 Nov 20.


Iso-osmolality versus low-osmolality iodinated contrast medium at intravenous contrast-enhanced CT: effect on kidney function.

Nguyen SA, Suranyi P, Ravenel JG, Randall PK, Romano PB, Strom KA, Costello P, Schoepf UJ.

Radiology. 2008 Jul;248(1):97-105. doi: 10.1148/radiol.2481071484. Epub 2008 May 15.


Effect of naltrexone and ondansetron on alcohol cue-induced activation of the ventral striatum in alcohol-dependent people.

Myrick H, Anton RF, Li X, Henderson S, Randall PK, Voronin K.

Arch Gen Psychiatry. 2008 Apr;65(4):466-75. doi: 10.1001/archpsyc.65.4.466.


Improving acceptance of naltrexone in community addiction treatment centers: a pilot study.

Thomas SE, Miller PM, Randall PK, Book SW.

J Subst Abuse Treat. 2008 Oct;35(3):260-8. doi: 10.1016/j.jsat.2007.11.001. Epub 2008 Mar 7.


A complex relationship between co-occurring social anxiety and alcohol use disorders: what effect does treating social anxiety have on drinking?

Thomas SE, Randall PK, Book SW, Randall CL.

Alcohol Clin Exp Res. 2008 Jan;32(1):77-84. Epub 2007 Nov 20.


Appetitive nature of drug cues re-confirmed with physiological measures and the potential role of stage of change.

Dempsey JP, Cohen LM, Hobson VL, Randall PK.

Psychopharmacology (Berl). 2007 Oct;194(2):253-60. Epub 2007 Jun 24.


Intravenous cocaine self-administration: individual differences in male and female C57BL/6J mice.

Griffin WC 3rd, Randall PK, Middaugh LD.

Pharmacol Biochem Behav. 2007 Jun-Jul;87(2):267-79. Epub 2007 May 5.


Self-reported sleep, sleepiness, and repeated alcohol withdrawals: a randomized, double blind, controlled comparison of lorazepam vs gabapentin.

Malcolm R, Myrick LH, Veatch LM, Boyle E, Randall PK.

J Clin Sleep Med. 2007 Feb 15;3(1):24-32.


Paroxetine reduces social anxiety in individuals with a co-occurring alcohol use disorder.

Book SW, Thomas SE, Randall PK, Randall CL.

J Anxiety Disord. 2008;22(2):310-8. Epub 2007 Mar 12.


The impact of alcohol dependence and posttraumatic stress disorder on cold pressor task response.

Brady KT, Waldrop AE, McRae AL, Back SE, Saladin ME, Upadhyaya HP, Anton RF, Randall PK.

J Stud Alcohol. 2006 Sep;67(5):700-6.


Cold pressor task reactivity: predictors of alcohol use among alcohol-dependent individuals with and without comorbid posttraumatic stress disorder.

Brady KT, Back SE, Waldrop AE, McRae AL, Anton RF, Upadhyaya HP, Saladin ME, Randall PK.

Alcohol Clin Exp Res. 2006 Jun;30(6):938-46.


Patterns of gene expression in the frontal cortex discriminate alcoholic from nonalcoholic individuals.

Liu J, Lewohl JM, Harris RA, Iyer VR, Dodd PR, Randall PK, Mayfield RD.

Neuropsychopharmacology. 2006 Jul;31(7):1574-82. Epub 2005 Nov 2.


The relationship between women's subjective and physiological sexual arousal.

Rellini AH, McCall KM, Randall PK, Meston CM.

Psychophysiology. 2005 Jan;42(1):116-24.


Gene expression profiling of individual cases reveals consistent transcriptional changes in alcoholic human brain.

Liu J, Lewohl JM, Dodd PR, Randall PK, Harris RA, Mayfield RD.

J Neurochem. 2004 Sep;90(5):1050-8.

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