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Items: 14


An elusive adenylate cyclase complicit in cholera is exposed.

Randak CO.

J Biol Chem. 2018 Aug 17;293(33):12960-12961. doi: 10.1074/jbc.H118.004669. Review.


Monocyte derived macrophages from CF pigs exhibit increased inflammatory responses at birth.

Paemka L, McCullagh BN, Abou Alaiwa MH, Stoltz DA, Dong Q, Randak CO, Gray RD, McCray PB Jr.

J Cyst Fibros. 2017 Jul;16(4):471-474. doi: 10.1016/j.jcf.2017.03.007. Epub 2017 Apr 1.


Airway acidification initiates host defense abnormalities in cystic fibrosis mice.

Shah VS, Meyerholz DK, Tang XX, Reznikov L, Abou Alaiwa M, Ernst SE, Karp PH, Wohlford-Lenane CL, Heilmann KP, Leidinger MR, Allen PD, Zabner J, McCray PB Jr, Ostedgaard LS, Stoltz DA, Randak CO, Welsh MJ.

Science. 2016 Jan 29;351(6272):503-7. doi: 10.1126/science.aad5589.


ATP and AMP mutually influence their interaction with the ATP-binding cassette (ABC) adenylate kinase cystic fibrosis transmembrane conductance regulator (CFTR) at separate binding sites.

Randak CO, Dong Q, Ver Heul AR, Elcock AH, Welsh MJ.

J Biol Chem. 2013 Sep 20;288(38):27692-701. doi: 10.1074/jbc.M113.479675. Epub 2013 Aug 6.


CFTR-deficient pigs display peripheral nervous system defects at birth.

Reznikov LR, Dong Q, Chen JH, Moninger TO, Park JM, Zhang Y, Du J, Hildebrand MS, Smith RJ, Randak CO, Stoltz DA, Welsh MJ.

Proc Natl Acad Sci U S A. 2013 Feb 19;110(8):3083-8. doi: 10.1073/pnas.1222729110. Epub 2013 Feb 4.


A child with progressive multiple tracheal diverticulae: a variation of the Mounier-Kuhn syndrome.

Randak CO, Weinberger M.

Pediatr Pulmonol. 2013 Aug;48(8):841-3. doi: 10.1002/ppul.22663. Epub 2012 Sep 4.


A mutation in CFTR modifies the effects of the adenylate kinase inhibitor Ap5A on channel gating.

Dong Q, Randak CO, Welsh MJ.

Biophys J. 2008 Dec;95(11):5178-85. doi: 10.1529/biophysj.108.140897. Epub 2008 Sep 19.


Role of CFTR's intrinsic adenylate kinase activity in gating of the Cl(-) channel.

Randak CO, Welsh MJ.

J Bioenerg Biomembr. 2007 Dec;39(5-6):473-9. Review.


Processing and function of CFTR-DeltaF508 are species-dependent.

Ostedgaard LS, Rogers CS, Dong Q, Randak CO, Vermeer DW, Rokhlina T, Karp PH, Welsh MJ.

Proc Natl Acad Sci U S A. 2007 Sep 25;104(39):15370-5. Epub 2007 Sep 14.


Adenylate kinase activity in ABC transporters.

Randak CO, Welsh MJ.

J Biol Chem. 2005 Oct 14;280(41):34385-8. Epub 2005 Aug 12. Review. No abstract available.


Curcumin stimulates cystic fibrosis transmembrane conductance regulator Cl- channel activity.

Berger AL, Randak CO, Ostedgaard LS, Karp PH, Vermeer DW, Welsh MJ.

J Biol Chem. 2005 Feb 18;280(7):5221-6. Epub 2004 Dec 6.

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