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Items: 19

1.

Design of selective thrombin inhibitors based on the (R)-Phe-Pro-Arg sequence.

Danilewicz JC, Abel SM, Brown AD, Fish PV, Hawkeswood E, Holland SJ, James K, McElroy AB, Overington J, Powling MJ, Rance DJ.

J Med Chem. 2002 Jun 6;45(12):2432-53.

PMID:
12036353
2.

Pharmacokinetics, pharmacodynamics, and safety of the 5-HT(1B/1D) agonist eletriptan following intravenous and oral administration.

Milton KA, Scott NR, Allen MJ, Abel S, Jenkins VC, James GC, Rance DJ, Eve MD.

J Clin Pharmacol. 2002 May;42(5):528-39.

PMID:
12017347
3.

Comparative human pharmacokinetics and metabolism of single-dose oral and intravenous sildenafil.

Muirhead GJ, Rance DJ, Walker DK, Wastall P.

Br J Clin Pharmacol. 2002;53 Suppl 1:13S-20S.

4.
5.

Pharmacokinetics and metabolism of sildenafil in mouse, rat, rabbit, dog and man.

Walker DK, Ackland MJ, James GC, Muirhead GJ, Rance DJ, Wastall P, Wright PA.

Xenobiotica. 1999 Mar;29(3):297-310.

PMID:
10219969
6.

A universal radiochemical high-performance liquid chromatographic assay for the determination of UDP-glucuronosyltransferase activity.

Ethell BT, Anderson GD, Beaumont K, Rance DJ, Burchell B.

Anal Biochem. 1998 Jan 1;255(1):142-7.

PMID:
9448853
7.

The prediction of human pharmacokinetic parameters from preclinical and in vitro metabolism data.

Obach RS, Baxter JG, Liston TE, Silber BM, Jones BC, MacIntyre F, Rance DJ, Wastall P.

J Pharmacol Exp Ther. 1997 Oct;283(1):46-58.

PMID:
9336307
9.

Biotransformation of carbazeran in guinea pig: effect of hydralazine pretreatment.

Critchley DJ, Rance DJ, Beedham C.

Xenobiotica. 1994 Jan;24(1):37-47.

PMID:
8165820
10.
11.

Bioanalytical data in decision making: discovery and development.

Smith DA, Beaumont K, Cussans NJ, Humphrey MJ, Jezequel SG, Rance DJ, Stopher DA, Walker DK.

Xenobiotica. 1992 Sep-Oct;22(9-10):1195-205. Review.

PMID:
1441610
12.

Subcellular localisation of guinea pig hepatic molybdenum hydroxylases.

Critchley DJ, Rance DJ, Beedham C.

Biochem Biophys Res Commun. 1992 May 29;185(1):54-9.

PMID:
1599489
14.
15.

1-substituted phthalazines as probes of the substrate-binding site of mammalian molybdenum hydroxylases.

Beedham C, Bruce SE, Critchley DJ, Rance DJ.

Biochem Pharmacol. 1990 Apr 1;39(7):1213-21.

PMID:
2322306
16.

Analysis of a novel cardiac stimulant, UK-61 260, in human plasma by gas chromatography-mass spectrometry with selected-ion monitoring.

Macrae PV, Rance DJ, Dankers J, Duchateau GS.

J Chromatogr. 1989 Jul 21;491(2):439-47. No abstract available.

PMID:
2553760
17.

Tissue distribution of the molybdenum hydroxylases, aldehyde oxidase and xanthine oxidase, in male and female guinea pigs.

Beedham C, Bruce SE, Rance DJ.

Eur J Drug Metab Pharmacokinet. 1987 Oct-Dec;12(4):303-6.

PMID:
3449390
18.

Species variation in hepatic aldehyde oxidase activity.

Beedham C, Bruce SE, Critchley DJ, al-Tayib Y, Rance DJ.

Eur J Drug Metab Pharmacokinet. 1987 Oct-Dec;12(4):307-10.

PMID:
3130251
19.

Oxidative metabolism of carbazeran in vitro by liver cytosol of baboon and man.

Kaye B, Rance DJ, Waring L.

Xenobiotica. 1985 Mar;15(3):237-42.

PMID:
4024658

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