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Items: 1 to 50 of 135

1.

The long noncoding RNA ROCKI regulates inflammatory gene expression.

Zhang Q, Chao TC, Patil VS, Qin Y, Tiwari SK, Chiou J, Dobin A, Tsai CM, Li Z, Dang J, Gupta S, Urdahl K, Nizet V, Gingeras TR, Gaulton KJ, Rana TM.

EMBO J. 2019 Apr 15;38(8). pii: e100041. doi: 10.15252/embj.2018100041. Epub 2019 Mar 27.

2.

HIV-1 Escape from Small-Molecule Antagonism of Vif.

Sharkey M, Sharova N, Mohammed I, Huff SE, Kummetha IR, Singh G, Rana TM, Stevenson M.

MBio. 2019 Feb 26;10(1). pii: e00144-19. doi: 10.1128/mBio.00144-19.

3.

Profiling of N6-Methyladenosine in Zika Virus RNA and Host Cellular mRNA.

Lichinchi G, Rana TM.

Methods Mol Biol. 2019;1870:209-218. doi: 10.1007/978-1-4939-8808-2_16.

PMID:
30539558
4.

Lipoprotein lipase regulates hematopoietic stem progenitor cell maintenance through DHA supply.

Liu C, Han T, Stachura DL, Wang H, Vaisman BL, Kim J, Klemke RL, Remaley AT, Rana TM, Traver D, Miller YI.

Nat Commun. 2018 Apr 3;9(1):1310. doi: 10.1038/s41467-018-03775-y.

5.

Next-Generation Sequencing of Genome-Wide CRISPR Screens.

Yau EH, Rana TM.

Methods Mol Biol. 2018;1712:203-216. doi: 10.1007/978-1-4939-7514-3_13.

6.

Genome-Wide CRISPR Screen for Essential Cell Growth Mediators in Mutant KRAS Colorectal Cancers.

Yau EH, Kummetha IR, Lichinchi G, Tang R, Zhang Y, Rana TM.

Cancer Res. 2017 Nov 15;77(22):6330-6339. doi: 10.1158/0008-5472.CAN-17-2043. Epub 2017 Sep 27.

7.

Zika virus infection reprograms global transcription of host cells to allow sustained infection.

Tiwari SK, Dang J, Qin Y, Lichinchi G, Bansal V, Rana TM.

Emerg Microbes Infect. 2017 Apr 26;6(4):e24. doi: 10.1038/emi.2017.9.

8.

miR-34 Modulates Innate Immunity and Ecdysone Signaling in Drosophila.

Xiong XP, Kurthkoti K, Chang KY, Li JL, Ren X, Ni JQ, Rana TM, Zhou R.

PLoS Pathog. 2016 Nov 28;12(11):e1006034. doi: 10.1371/journal.ppat.1006034. eCollection 2016 Nov.

9.

A Herpesvirus Protein Selectively Inhibits Cellular mRNA Nuclear Export.

Gong D, Kim YH, Xiao Y, Du Y, Xie Y, Lee KK, Feng J, Farhat N, Zhao D, Shu S, Dai X, Chanda SK, Rana TM, Krogan NJ, Sun R, Wu TT.

Cell Host Microbe. 2016 Nov 9;20(5):642-653. doi: 10.1016/j.chom.2016.10.004.

10.

Identification of novel genes and networks governing hematopoietic stem cell development.

Han T, Yang CS, Chang KY, Zhang D, Imam FB, Rana TM.

EMBO Rep. 2016 Dec;17(12):1814-1828. Epub 2016 Oct 26.

11.

Dynamics of Human and Viral RNA Methylation during Zika Virus Infection.

Lichinchi G, Zhao BS, Wu Y, Lu Z, Qin Y, He C, Rana TM.

Cell Host Microbe. 2016 Nov 9;20(5):666-673. doi: 10.1016/j.chom.2016.10.002. Epub 2016 Oct 20.

12.

miR-1298 Inhibits Mutant KRAS-Driven Tumor Growth by Repressing FAK and LAMB3.

Zhou Y, Dang J, Chang KY, Yau E, Aza-Blanc P, Moscat J, Rana TM.

Cancer Res. 2016 Oct 1;76(19):5777-5787.

13.

Dynamics of the human and viral m(6)A RNA methylomes during HIV-1 infection of T cells.

Lichinchi G, Gao S, Saletore Y, Gonzalez GM, Bansal V, Wang Y, Mason CE, Rana TM.

Nat Microbiol. 2016 Feb 22;1:16011. doi: 10.1038/nmicrobiol.2016.11.

14.

1,2,3-Triazoles as Amide Bioisosteres: Discovery of a New Class of Potent HIV-1 Vif Antagonists.

Mohammed I, Kummetha IR, Singh G, Sharova N, Lichinchi G, Dang J, Stevenson M, Rana TM.

J Med Chem. 2016 Aug 25;59(16):7677-82. doi: 10.1021/acs.jmedchem.6b00247. Epub 2016 Aug 10.

15.

Polycomb Group Protein Pcgf6 Acts as a Master Regulator to Maintain Embryonic Stem Cell Identity.

Yang CS, Chang KY, Dang J, Rana TM.

Sci Rep. 2016 Jun 1;6:26899. doi: 10.1038/srep26899.

16.

Zika Virus Depletes Neural Progenitors in Human Cerebral Organoids through Activation of the Innate Immune Receptor TLR3.

Dang J, Tiwari SK, Lichinchi G, Qin Y, Patil VS, Eroshkin AM, Rana TM.

Cell Stem Cell. 2016 Aug 4;19(2):258-265. doi: 10.1016/j.stem.2016.04.014. Epub 2016 May 6.

17.

P-TEFb regulation of transcription termination factor Xrn2 revealed by a chemical genetic screen for Cdk9 substrates.

Sansó M, Levin RS, Lipp JJ, Wang VY, Greifenberg AK, Quezada EM, Ali A, Ghosh A, Larochelle S, Rana TM, Geyer M, Tong L, Shokat KM, Fisher RP.

Genes Dev. 2016 Jan 1;30(1):117-31. doi: 10.1101/gad.269589.115.

18.

Haunting the HOXA Locus: Two Faces of lncRNA Regulation.

Lin N, Dang J, Rana TM.

Cell Stem Cell. 2015 May 7;16(5):449-50. doi: 10.1016/j.stem.2015.04.010.

19.

Enhancing Induced Pluripotent Stem Cell Generation by MicroRNA.

Dang J, Rana TM.

Methods Mol Biol. 2016;1357:71-84. doi: 10.1007/7651_2015_201.

PMID:
25687299
20.

Therapeutic targeting of polo-like kinase 1 using RNA-interfering nanoparticles (iNOPs) for the treatment of non-small cell lung cancer.

McCarroll JA, Dwarte T, Baigude H, Dang J, Yang L, Erlich RB, Kimpton K, Teo J, Sagnella SM, Akerfeldt MC, Liu J, Phillips PA, Rana TM, Kavallaris M.

Oncotarget. 2015 May 20;6(14):12020-34.

21.

Preparation of novel curdlan nanoparticles for intracellular siRNA delivery.

Han J, Cai J, Borjihan W, Ganbold T, Rana TM, Baigude H.

Carbohydr Polym. 2015 Mar 6;117:324-30. doi: 10.1016/j.carbpol.2014.09.069. Epub 2014 Oct 5.

22.

Strategies to antagonize miRNA functions in vitro and in vivo.

Baigude H, Rana TM.

Nanomedicine (Lond). 2014 Nov;9(16):2545-55. doi: 10.2217/nnm.14.162. Review.

PMID:
25490425
23.

Decoding the noncoding: prospective of lncRNA-mediated innate immune regulation.

Li Z, Rana TM.

RNA Biol. 2014;11(8):979-85. doi: 10.4161/rna.29937. Epub 2014 Oct 31.

24.

MicroRNA-mediated regulation of extracellular matrix formation modulates somatic cell reprogramming.

Li Z, Dang J, Chang KY, Rana TM.

RNA. 2014 Dec;20(12):1900-15. doi: 10.1261/rna.043745.113. Epub 2014 Oct 21.

25.

Genome-wide functional analysis reveals factors needed at the transition steps of induced reprogramming.

Yang CS, Chang KY, Rana TM.

Cell Rep. 2014 Jul 24;8(2):327-37. doi: 10.1016/j.celrep.2014.07.002. Epub 2014 Jul 17.

26.

Therapeutic targeting of microRNAs: current status and future challenges.

Li Z, Rana TM.

Nat Rev Drug Discov. 2014 Aug;13(8):622-38. doi: 10.1038/nrd4359. Epub 2014 Jul 11. Review.

PMID:
25011539
27.

Kinome-wide functional analysis highlights the role of cytoskeletal remodeling in somatic cell reprogramming.

Sakurai K, Talukdar I, Patil VS, Dang J, Li Z, Chang KY, Lu CC, Delorme-Walker V, Dermardirossian C, Anderson K, Hanein D, Yang CS, Wu D, Liu Y, Rana TM.

Cell Stem Cell. 2014 Apr 3;14(4):523-34. doi: 10.1016/j.stem.2014.03.001.

28.

An evolutionarily conserved long noncoding RNA TUNA controls pluripotency and neural lineage commitment.

Lin N, Chang KY, Li Z, Gates K, Rana ZA, Dang J, Zhang D, Han T, Yang CS, Cunningham TJ, Head SR, Duester G, Dong PD, Rana TM.

Mol Cell. 2014 Mar 20;53(6):1005-19. doi: 10.1016/j.molcel.2014.01.021. Epub 2014 Feb 13. Erratum in: Mol Cell. 2014 Mar 20;53(6):1067.

29.

Staged miRNA re-regulation patterns during reprogramming.

Henzler CM, Li Z, Dang J, Arcila ML, Zhou H, Liu J, Chang KY, Bassett DS, Rana TM, Kosik KS.

Genome Biol. 2013 Dec 31;14(12):R149. doi: 10.1186/gb-2013-14-12-r149.

30.

The long noncoding RNA THRIL regulates TNFα expression through its interaction with hnRNPL.

Li Z, Chao TC, Chang KY, Lin N, Patil VS, Shimizu C, Head SR, Burns JC, Rana TM.

Proc Natl Acad Sci U S A. 2014 Jan 21;111(3):1002-7. doi: 10.1073/pnas.1313768111. Epub 2013 Dec 26.

31.

In Vivo Delivery of RNAi by Reducible Interfering Nanoparticles (iNOPs).

Baigude H, Su J, McCarroll J, Rana TM.

ACS Med Chem Lett. 2013 Aug 8;4(8):720-723. Epub 2013 Jun 18.

32.

Efficient Computation of Small-Molecule Configurational Binding Entropy and Free Energy Changes by Ensemble Enumeration.

Silver NW, King BM, Nalam MN, Cao H, Ali A, Kiran Kumar Reddy GS, Rana TM, Schiffer CA, Tidor B.

J Chem Theory Comput. 2013 Nov 12;9(11):5098-5115. Epub 2013 Aug 7.

33.

Gene regulation by non-coding RNAs.

Patil VS, Zhou R, Rana TM.

Crit Rev Biochem Mol Biol. 2014 Jan-Feb;49(1):16-32. doi: 10.3109/10409238.2013.844092. Epub 2013 Oct 28. Review.

34.

Core small nuclear ribonucleoprotein particle splicing factor SmD1 modulates RNA interference in Drosophila.

Xiong XP, Kurthkoti K, Chang KY, Lichinchi G, De N, Schneemann A, MacRae IJ, Rana TM, Perrimon N, Zhou R.

Proc Natl Acad Sci U S A. 2013 Oct 8;110(41):16520-5. doi: 10.1073/pnas.1315803110. Epub 2013 Sep 25.

35.

Substrate envelope-designed potent HIV-1 protease inhibitors to avoid drug resistance.

Nalam MN, Ali A, Reddy GS, Cao H, Anjum SG, Altman MD, Yilmaz NK, Tidor B, Rana TM, Schiffer CA.

Chem Biol. 2013 Sep 19;20(9):1116-24. doi: 10.1016/j.chembiol.2013.07.014. Epub 2013 Sep 5.

36.

Testing the substrate-envelope hypothesis with designed pairs of compounds.

Shen Y, Altman MD, Ali A, Nalam MN, Cao H, Rana TM, Schiffer CA, Tidor B.

ACS Chem Biol. 2013 Nov 15;8(11):2433-41. doi: 10.1021/cb400468c. Epub 2013 Sep 26.

37.

RNA-based mechanisms regulating host-virus interactions.

Zhou R, Rana TM.

Immunol Rev. 2013 May;253(1):97-111. doi: 10.1111/imr.12053. Review.

38.

Learning the molecular mechanisms of the reprogramming factors: let's start from microRNAs.

Yang CS, Rana TM.

Mol Biosyst. 2013 Jan 27;9(1):10-7. doi: 10.1039/c2mb25088h. Epub 2012 Oct 5. Review.

39.
40.

Design, synthesis, and biological and structural evaluations of novel HIV-1 protease inhibitors to combat drug resistance.

Parai MK, Huggins DJ, Cao H, Nalam MN, Ali A, Schiffer CA, Tidor B, Rana TM.

J Med Chem. 2012 Jul 26;55(14):6328-41. doi: 10.1021/jm300238h. Epub 2012 Jul 13.

41.

SAR and Lead Optimization of an HIV-1 Vif-APOBEC3G Axis Inhibitor.

Mohammed I, Parai MK, Jiang X, Sharova N, Singh G, Stevenson M, Rana TM.

ACS Med Chem Lett. 2012 Jun 14;3(6):465-469.

43.

Interfering nanoparticles for silencing microRNAs.

Baigude H, Rana TM.

Methods Enzymol. 2012;509:339-53. doi: 10.1016/B978-0-12-391858-1.00017-4.

44.

miR-TRAP: a benchtop chemical biology strategy to identify microRNA targets.

Baigude H, Ahsanullah, Li Z, Zhou Y, Rana TM.

Angew Chem Int Ed Engl. 2012 Jun 11;51(24):5880-3. doi: 10.1002/anie.201201512. Epub 2012 May 8. No abstract available.

45.

Synthesis and structure-activity relationship studies of HIV-1 virion infectivity factor (Vif) inhibitors that block viral replication.

Ali A, Wang J, Nathans RS, Cao H, Sharova N, Stevenson M, Rana TM.

ChemMedChem. 2012 Jul;7(7):1217-29. doi: 10.1002/cmdc.201200079. Epub 2012 May 3.

46.

Deep annotation of mouse iso-miR and iso-moR variation.

Zhou H, Arcila ML, Li Z, Lee EJ, Henzler C, Liu J, Rana TM, Kosik KS.

Nucleic Acids Res. 2012 Jul;40(13):5864-75. doi: 10.1093/nar/gks247. Epub 2012 Mar 19.

47.

Using microRNAs to enhance the generation of induced pluripotent stem cells.

Li Z, Rana TM.

Curr Protoc Stem Cell Biol. 2012;Chapter 4:Unit 4A.4. doi: 10.1002/9780470151808.sc04a04s20.

PMID:
22415842
48.

Molecular mechanisms of RNA-triggered gene silencing machineries.

Li Z, Rana TM.

Acc Chem Res. 2012 Jul 17;45(7):1122-31. doi: 10.1021/ar200253u. Epub 2012 Feb 3.

49.
50.

microRNAs modulate iPS cell generation.

Yang CS, Li Z, Rana TM.

RNA. 2011 Aug;17(8):1451-60. doi: 10.1261/rna.2664111. Epub 2011 Jun 21.

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