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SHP2 Inhibition Prevents Adaptive Resistance to MEK inhibitors in Multiple Cancer Models.

Fedele C, Ran H, Diskin B, Wei W, Jen J, Geer MJ, Araki K, Ozerdem U, Simeone DM, Miller G, Neel BG, Tang KH.

Cancer Discov. 2018 Jul 25. pii: CD-18-0444. doi: 10.1158/2159-8290.CD-18-0444. [Epub ahead of print]


Modelling mass balance of cadmium in paddy soils under long term control scenarios.

Feng W, Guo Z, Peng C, Xiao X, Shi L, Han X, Ran H.

Environ Sci Process Impacts. 2018 Aug 16;20(8):1158-1166. doi: 10.1039/c8em00153g.


Phase-shift, targeted nanoparticles for ultrasound molecular imaging by low intensity focused ultrasound irradiation.

Li M, Luo H, Zhang W, He K, Chen Y, Liu J, Chen J, Wang D, Hao L, Ran H, Zheng Y, Wang Z, Li P.

Int J Nanomedicine. 2018 Jul 4;13:3907-3920. doi: 10.2147/IJN.S166200. eCollection 2018.


[Distribution and Accumulation of Cadmium in Paddy Soil and Rice Affected by Pollutant Sources Control and Improvement Measures].

Feng WL, Guo ZH, Shi L, Xiao XY, Han XQ, Ran HZ, Xue QH.

Huan Jing Ke Xue. 2018 Jan 8;39(1):399-405. doi: 10.13227/j.hjkx.201706233. Chinese.


PA/US dual-modality imaging to guide VEGFR-2 targeted photothermal therapy using ZnPc-/PFH-loaded polymeric nanoparticles.

Chen YL, Liu FQ, Guo Y, Cheng J, Yang L, Lu M, Li P, Xu J, Yu T, Wang ZG, Cao Y, Ran HT.

Biomater Sci. 2018 Jul 24;6(8):2130-2143. doi: 10.1039/c8bm00213d.


A preliminary study of photoacoustic/ultrasound dual-mode imaging in melanoma using MAGE-targeted gold nanoparticles.

Li X, Wang D, Ran H, Hao L, Cao Y, Ao M, Zhang N, Song J, Zhang L, Yi H, Wang Z, Li P.

Biochem Biophys Res Commun. 2018 Jul 12;502(2):255-261. doi: 10.1016/j.bbrc.2018.05.155. Epub 2018 May 25.


Cystatin F involvement in adenosine A2A receptor-mediated neuroinflammation in BV2 microglial cells.

Duan W, Wang H, Fan Q, Chen L, Huang H, Ran H.

Sci Rep. 2018 May 1;8(1):6820. doi: 10.1038/s41598-018-25031-5.


In Vivo Targeted, Responsive, and Synergistic Cancer Nanotheranostics by Magnetic Resonance Imaging-Guided Synergistic High-Intensity Focused Ultrasound Ablation and Chemotherapy.

Tang H, Guo Y, Peng L, Fang H, Wang Z, Zheng Y, Ran H, Chen Y.

ACS Appl Mater Interfaces. 2018 May 9;10(18):15428-15441. doi: 10.1021/acsami.8b01967. Epub 2018 Apr 25.


Screening potential reference genes for quantitative real-time PCR analysis in the oriental armyworm, Mythimna separata.

Li HB, Dai CG, Zhang CR, He YF, Ran HY, Chen SH.

PLoS One. 2018 Apr 4;13(4):e0195096. doi: 10.1371/journal.pone.0195096. eCollection 2018.


Possible bite-induced abscess and osteomyelitis in Lufengosaurus (Dinosauria: sauropodomorph) from the Lower Jurassic of the Yimen Basin, China.

Xing L, Rothschild BM, Randolph-Quinney PS, Wang Y, Parkinson AH, Ran H.

Sci Rep. 2018 Mar 22;8(1):5045. doi: 10.1038/s41598-018-23451-x.


Cell-penetrating Peptide-modified Targeted Drug-loaded Phase-transformation Lipid Nanoparticles Combined with Low-intensity Focused Ultrasound for Precision Theranostics against Hepatocellular Carcinoma.

Zhao H, Wu M, Zhu L, Tian Y, Wu M, Li Y, Deng L, Jiang W, Shen W, Wang Z, Mei Z, Li P, Ran H, Zhou Z, Ren J.

Theranostics. 2018 Feb 14;8(7):1892-1910. doi: 10.7150/thno.22386. eCollection 2018.


Novel gadopentetic acid-doped silica nanoparticles conjugated with YPSMA-1 targeting prostate cancer for MR imaging: an in vitro study.

Jiang W, He X, Fang H, Zhou X, Ran H, Guo D.

Biochem Biophys Res Commun. 2018 May 5;499(2):202-208. doi: 10.1016/j.bbrc.2018.03.124. Epub 2018 Mar 22.


Identification of key differentially expressed genes associated with non‑small cell lung cancer by bioinformatics analyses.

Xiao Y, Feng M, Ran H, Han X, Li X.

Mol Med Rep. 2018 May;17(5):6379-6386. doi: 10.3892/mmr.2018.8726. Epub 2018 Mar 9.


Stearoyl-CoA desaturase-1 promotes colorectal cancer metastasis in response to glucose by suppressing PTEN.

Ran H, Zhu Y, Deng R, Zhang Q, Liu X, Feng M, Zhong J, Lin S, Tong X, Su Q.

J Exp Clin Cancer Res. 2018 Mar 12;37(1):54. doi: 10.1186/s13046-018-0711-9.


Engineering of a Nanosized Biocatalyst for Combined Tumor Starvation and Low-Temperature Photothermal Therapy.

Zhou J, Li M, Hou Y, Luo Z, Chen Q, Cao H, Huo R, Xue C, Sutrisno L, Hao L, Cao Y, Ran H, Lu L, Li K, Cai K.

ACS Nano. 2018 Mar 27;12(3):2858-2872. doi: 10.1021/acsnano.8b00309. Epub 2018 Mar 12.


Drug Release from Phase-Changeable Nanodroplets Triggered by Low-Intensity Focused Ultrasound.

Cao Y, Chen Y, Yu T, Guo Y, Liu F, Yao Y, Li P, Wang D, Wang Z, Chen Y, Ran H.

Theranostics. 2018 Feb 2;8(5):1327-1339. doi: 10.7150/thno.21492. eCollection 2018.


Perfluorooctyl bromide & indocyanine green co-loaded nanoliposomes for enhanced multimodal imaging-guided phototherapy.

Sheng D, Liu T, Deng L, Zhang L, Li X, Xu J, Hao L, Li P, Ran H, Chen H, Wang Z.

Biomaterials. 2018 May;165:1-13. doi: 10.1016/j.biomaterials.2018.02.041. Epub 2018 Feb 24.


Extracranial vertebral artery dissection: Findings and advantages of ultrasonography.

Yang L, Ran H.

Medicine (Baltimore). 2018 Mar;97(9):e0067. doi: 10.1097/MD.0000000000010067.


Peptide-Functionalized Phase-Transformation Nanoparticles for Low Intensity Focused Ultrasound-Assisted Tumor Imaging and Therapy.

Zhu L, Zhao H, Zhou Z, Xia Y, Wang Z, Ran H, Li P, Ren J.

Nano Lett. 2018 Mar 14;18(3):1831-1841. doi: 10.1021/acs.nanolett.7b05087. Epub 2018 Feb 13.


A liquid crystalline precursor incorporating chlorhexidine acetate and silver nanoparticles for root canal disinfection.

Zheng T, Huang X, Chen J, Feng D, Mei L, Huang Y, Quan G, Zhu C, Singh V, Ran H, Pan X, Wu CY, Wu C.

Biomater Sci. 2018 Feb 27;6(3):596-603. doi: 10.1039/c7bm00764g.


Design and Synthesis of a Novel n-Type Polymer Based on Asymmetric Rylene Diimide for the Application in All-Polymer Solar Cells.

Yang J, Chen F, Ran H, Hu JY, Xiao B, Tang A, Wang X, Zhou E.

Macromol Rapid Commun. 2018 Jan 2. doi: 10.1002/marc.201700715. [Epub ahead of print]


Glucose-derived AGEs enhance human gastric cancer metastasis through RAGE/ERK/Sp1/MMP2 cascade.

Deng R, Mo F, Chang B, Zhang Q, Ran H, Yang S, Zhu Z, Hu L, Su Q.

Oncotarget. 2017 Oct 31;8(61):104216-104226. doi: 10.18632/oncotarget.22185. eCollection 2017 Nov 28.


Phase Transition Nanoparticles as Multimodality Contrast Agents for the Detection of Thrombi and for Targeting Thrombolysis: in Vitro and in Vivo Experiments.

Xu J, Zhou J, Zhong Y, Zhang Y, Liu J, Chen Y, Deng L, Sheng D, Wang Z, Ran H, Guo D.

ACS Appl Mater Interfaces. 2017 Dec 13;9(49):42525-42535. doi: 10.1021/acsami.7b12689. Epub 2017 Dec 1.


A Laser-Activated Biocompatible Theranostic Nanoagent for Targeted Multimodal Imaging and Photothermal Therapy.

Deng L, Cai X, Sheng D, Yang Y, Strohm EM, Wang Z, Ran H, Wang D, Zheng Y, Li P, Shang T, Ling Y, Wang F, Sun Y.

Theranostics. 2017 Oct 6;7(18):4410-4423. doi: 10.7150/thno.21283. eCollection 2017.


Novel dissolving microneedles for enhanced transdermal delivery of levonorgestrel: In vitro and in vivo characterization.

Yao G, Quan G, Lin S, Peng T, Wang Q, Ran H, Chen H, Zhang Q, Wang L, Pan X, Wu C.

Int J Pharm. 2017 Dec 20;534(1-2):378-386. doi: 10.1016/j.ijpharm.2017.10.035. Epub 2017 Oct 16.


[Correlation factors of 127 times pre-crisis state in patients with myasthenia gravis].

Ou CY, Ran H, Qiu L, Huang ZD, Lin ZZ, Deng J, Liu WB.

Zhonghua Yi Xue Za Zhi. 2017 Oct 10;97(37):2884-2889. doi: 10.3760/cma.j.issn.0376-2491.2017.37.002. Chinese.


Novel strategy for immunomodulation: Dissolving microneedle array encapsulating thymopentin fabricated by modified two-step molding technology.

Lin S, Cai B, Quan G, Peng T, Yao G, Zhu C, Wu Q, Ran H, Pan X, Wu C.

Eur J Pharm Biopharm. 2018 Jan;122:104-112. doi: 10.1016/j.ejpb.2017.10.011. Epub 2017 Oct 16.


Drug release from core-shell PVA/silk fibroin nanoparticles fabricated by one-step electrospraying.

Cao Y, Liu F, Chen Y, Yu T, Lou D, Guo Y, Li P, Wang Z, Ran H.

Sci Rep. 2017 Sep 20;7(1):11913. doi: 10.1038/s41598-017-12351-1.


Impact of ocean acidification on the early development and escape behavior of marine medaka (Oryzias melastigma).

Wang X, Song L, Chen Y, Ran H, Song J.

Mar Environ Res. 2017 Oct;131:10-18. doi: 10.1016/j.marenvres.2017.09.001. Epub 2017 Sep 6.


High-intensity focused ultrasound-triggered nanoscale bubble-generating liposomes for efficient and safe tumor ablation under photoacoustic imaging monitoring.

Feng G, Hao L, Xu C, Ran H, Zheng Y, Li P, Cao Y, Wang Q, Xia J, Wang Z.

Int J Nanomedicine. 2017 Jun 28;12:4647-4659. doi: 10.2147/IJN.S135391. eCollection 2017.


Preparation of Acid-Resistant Microcapsules with Shell-Matrix Structure to Enhance Stability of Streptococcus Thermophilus IFFI 6038.

Zhou HB, Chen J, Li S, Zhang J, Zhu CE, Ran H, Luo M, Pan X, Hu H, Wu C.

J Food Sci. 2017 Aug;82(8):1978-1984. doi: 10.1111/1750-3841.13774. Epub 2017 Jul 11.


Injectable PLGA/Fe3O4 implants carrying cisplatin for synergistic magnetic hyperthermal ablation of rabbit VX2 tumor.

Yang Y, Wang F, Zheng K, Deng L, Yang L, Zhang N, Xu C, Ran H, Wang Z, Wang Z, Zheng Y.

PLoS One. 2017 May 4;12(5):e0177049. doi: 10.1371/journal.pone.0177049. eCollection 2017.


Evaluation of left ventricular myocardial mechanics by three-dimensional speckle tracking echocardiography in the patients with different graded coronary artery stenosis.

Li L, Zhang PY, Ran H, Dong J, Fang LL, Ding QS.

Int J Cardiovasc Imaging. 2017 Oct;33(10):1513-1520. doi: 10.1007/s10554-017-1147-6. Epub 2017 Apr 28.


Nuclear Shp2 directs normal embryo implantation via facilitating the ERα tyrosine phosphorylation by the Src kinase.

Ran H, Kong S, Zhang S, Cheng J, Zhou C, He B, Xin Q, Lydon JP, DeMayo FJ, Feng GS, Xia G, Lu Z, Wang C, Wang H.

Proc Natl Acad Sci U S A. 2017 May 2;114(18):4816-4821. doi: 10.1073/pnas.1700978114. Epub 2017 Apr 19.


Phase-Transition Nanodroplets for Real-Time Photoacoustic/Ultrasound Dual-Modality Imaging and Photothermal Therapy of Sentinel Lymph Node in Breast Cancer.

Yang L, Cheng J, Chen Y, Yu S, Liu F, Sun Y, Chen Y, Ran H.

Sci Rep. 2017 Mar 24;7:45213. doi: 10.1038/srep45213.


The advantage of ultrasonography in the diagnosis of extracranial vertebral artery dissection: Two case reports.

Yang L, Ran H.

Medicine (Baltimore). 2017 Mar;96(12):e6379. doi: 10.1097/MD.0000000000006379.


Magnetic nanobubbles with potential for targeted drug delivery and trimodal imaging in breast cancer: an in vitro study.

Song W, Luo Y, Zhao Y, Liu X, Zhao J, Luo J, Zhang Q, Ran H, Wang Z, Guo D.

Nanomedicine (Lond). 2017 May;12(9):991-1009. doi: 10.2217/nnm-2017-0027. Epub 2017 Mar 13.


Response to: Phylogenetic placement, developmental trajectories and evolutionary implications of a feathered dinosaur tail in Mid-Cretaceous amber.

Xing L, McKellar RC, Xu X, Li G, Bai M, Persons WS 4th, Miyashita T, Benton MJ, Zhang J, Wolfe AP, Yi Q, Tseng K, Ran H, Currie PJ.

Curr Biol. 2017 Mar 20;27(6):R216-R217. doi: 10.1016/j.cub.2017.02.023.


A split-face comparison of Q-switched Nd:YAG 1064-nm laser for facial rejuvenation in Nevus of Ota patients.

Yongqian C, Li L, Jianhai B, Ran H, Li G, Hao W, Xining W, Shigang X, Yibing W.

Lasers Med Sci. 2017 May;32(4):765-769. doi: 10.1007/s10103-017-2161-6. Epub 2017 Mar 15.


A novel design for stable self-assembly cubosome precursor-microparticles enhancing dissolution of insoluble drugs.

Mei L, Xie Y, Jing H, Huang Y, Chen J, Ran H, Pan X, Wu C.

Drug Dev Ind Pharm. 2017 Aug;43(8):1239-1243. doi: 10.1080/03639045.2017.1304958. Epub 2017 Mar 26.


Glucose-derived AGEs promote migration and invasion of colorectal cancer by up-regulating Sp1 expression.

Deng R, Wu H, Ran H, Kong X, Hu L, Wang X, Su Q.

Biochim Biophys Acta. 2017 May;1861(5 Pt A):1065-1074. doi: 10.1016/j.bbagen.2017.02.024. Epub 2017 Feb 22.


Low-intensity focused ultrasound (LIFU)-induced acoustic droplet vaporization in phase-transition perfluoropentane nanodroplets modified by folate for ultrasound molecular imaging.

Liu J, Shang T, Wang F, Cao Y, Hao L, Ren J, Ran H, Wang Z, Li P, Du Z.

Int J Nanomedicine. 2017 Jan 27;12:911-923. doi: 10.2147/IJN.S122667. eCollection 2017.


Melatonin alleviates cadmium-induced liver injury by inhibiting the TXNIP-NLRP3 inflammasome.

Cao Z, Fang Y, Lu Y, Tan D, Du C, Li Y, Ma Q, Yu J, Chen M, Zhou C, Pei L, Zhang L, Ran H, He M, Yu Z, Zhou Z.

J Pineal Res. 2017 Apr;62(3). doi: 10.1111/jpi.12389. Epub 2017 Mar 10.


A Feathered Dinosaur Tail with Primitive Plumage Trapped in Mid-Cretaceous Amber.

Xing L, McKellar RC, Xu X, Li G, Bai M, Persons WS 4th, Miyashita T, Benton MJ, Zhang J, Wolfe AP, Yi Q, Tseng K, Ran H, Currie PJ.

Curr Biol. 2016 Dec 19;26(24):3352-3360. doi: 10.1016/j.cub.2016.10.008. Epub 2016 Dec 8.


Low-intensity focused ultrasound mediated localized drug delivery for liver tumors in rabbits.

Gong Y, Wang Z, Dong G, Sun Y, Wang X, Rong Y, Li M, Wang D, Ran H.

Drug Deliv. 2016 Sep;23(7):2280-2289. Epub 2014 Nov 4.


Right ventricular function in pulmonary hypertension due to left heart disease by two-dimensional speckle tracking and real time three-dimensional echocardiography.

Zhang L, Zhang P, Qi H, Wang Z, Luo T, Lu M, Ran H, Cao C, Ren J.

Acta Cardiol. 2016 Aug;71(4):473-82. doi: 10.2143/AC.71.4.3159702. No abstract available.


Microwave-activated nanodroplet vaporization for highly efficient tumor ablation with real-time monitoring performance.

Xu J, Chen Y, Deng L, Liu J, Cao Y, Li P, Ran H, Zheng Y, Wang Z.

Biomaterials. 2016 Nov;106:264-75. doi: 10.1016/j.biomaterials.2016.08.034. Epub 2016 Aug 20.


Sticking It to Cancer with Molecular Glue for SHP2.

Ran H, Tsutsumi R, Araki T, Neel BG.

Cancer Cell. 2016 Aug 8;30(2):194-196. doi: 10.1016/j.ccell.2016.07.010.


Assessment of Left Ventricular Myocardial Viability by 3-Dimensional Speckle-Tracking Echocardiography in Patients With Myocardial Infarction.

Ran H, Zhang PY, Zhang YX, Zhang JX, Wu WF, Dong J, Ma XW.

J Ultrasound Med. 2016 Aug;35(8):1631-8. doi: 10.7863/ultra.15.09032. Epub 2016 Jun 14.


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