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Items: 35

1.

Assessing the safety and immunogenicity of recombinant vesicular stomatitis virus Ebola vaccine in healthy adults: a randomized clinical trial.

ElSherif MS, Brown C, MacKinnon-Cameron D, Li L, Racine T, Alimonti J, Rudge TL, Sabourin C, Silvera P, Hooper JW, Kwilas SA, Kilgore N, Badorrek C, Ramsey WJ, Heppner DG, Kemp T, Monath TP, Nowak T, McNeil SA, Langley JM, Halperin SA; Canadian Immunization Research Network.

CMAJ. 2017 Jun 19;189(24):E819-E827. doi: 10.1503/cmaj.170074.

2.

Safety and immunogenicity of the rVSV∆G-ZEBOV-GP Ebola virus vaccine candidate in healthy adults: a phase 1b randomised, multicentre, double-blind, placebo-controlled, dose-response study.

Heppner DG Jr, Kemp TL, Martin BK, Ramsey WJ, Nichols R, Dasen EJ, Link CJ, Das R, Xu ZJ, Sheldon EA, Nowak TA, Monath TP; V920-004 study team.

Lancet Infect Dis. 2017 Aug;17(8):854-866. doi: 10.1016/S1473-3099(17)30313-4. Epub 2017 Jun 9.

PMID:
28606591
3.

A Recombinant Vesicular Stomatitis Virus Ebola Vaccine.

Regules JA, Beigel JH, Paolino KM, Voell J, Castellano AR, Hu Z, Muñoz P, Moon JE, Ruck RC, Bennett JW, Twomey PS, Gutiérrez RL, Remich SA, Hack HR, Wisniewski ML, Josleyn MD, Kwilas SA, Van Deusen N, Mbaya OT, Zhou Y, Stanley DA, Jing W, Smith KS, Shi M, Ledgerwood JE, Graham BS, Sullivan NJ, Jagodzinski LL, Peel SA, Alimonti JB, Hooper JW, Silvera PM, Martin BK, Monath TP, Ramsey WJ, Link CJ, Lane HC, Michael NL, Davey RT Jr, Thomas SJ; rVSVΔG-ZEBOV-GP Study Group.

N Engl J Med. 2017 Jan 26;376(4):330-341. doi: 10.1056/NEJMoa1414216. Epub 2015 Apr 1.

4.

Combination immunotherapy for high-risk resected and metastatic melanoma patients.

Riker AI, Rossi GR, Masih P, Alsfeld LC, Denham F, Tennant L, Ramsey WJ, Vahanian NN, Link CJ.

Ochsner J. 2014 Summer;14(2):164-74.

5.

U6 promoter-enhanced GlnUAG suppressor tRNA has higher suppression efficacy and can be stably expressed in 293 cells.

Koukuntla R, Ramsey WJ, Young WB, Link CJ.

J Gene Med. 2013 Feb;15(2):93-101. doi: 10.1002/jgm.2696.

PMID:
23303531
6.

Cellular immunotherapy study of prostate cancer patients and resulting IgG responses to peptide epitopes predicted from prostate tumor-associated autoantigens.

Hemstreet GP 3rd, Rossi GR, Pisarev VM, Enke CA, Helfner L, Hauke RJ, Tennant L, Ramsey WJ, Vahanian NN, Link CJ.

J Immunother. 2013 Jan;36(1):57-65. doi: 10.1097/CJI.0b013e3182780abc.

PMID:
23211622
7.

Allogeneic melanoma vaccine expressing alphaGal epitopes induces antitumor immunity to autologous antigens in mice without signs of toxicity.

Rossi GR, Mautino MR, Awwad DZ, Husske K, Lejukole H, Koenigsfeld M, Ramsey WJ, Vahanian N, Link CJ.

J Immunother. 2008 Jul-Aug;31(6):545-54. doi: 10.1097/CJI.0b013e31817d2f45.

PMID:
18528300
8.

Trans-complementing adenoviral vectors for oncolytic therapy of malignant melanoma.

Wolkersdörfer GW, Morris JC, Ehninger G, Ramsey WJ.

J Gene Med. 2004 Jun;6(6):652-62.

PMID:
15170736
9.

In situ generation of pseudotyped retroviral progeny by adenovirus-mediated transduction of tumor cells enhances the killing effect of HSV-tk suicide gene therapy in vitro and in vivo.

Okada T, Caplen NJ, Ramsey WJ, Onodera M, Shimazaki K, Nomoto T, Ajalli R, Wildner O, Morris J, Kume A, Hamada H, Blaese RM, Ozawa K.

J Gene Med. 2004 Mar;6(3):288-99.

PMID:
15026990
10.
11.

Persistence and expression of the adenosine deaminase gene for 12 years and immune reaction to gene transfer components: long-term results of the first clinical gene therapy trial.

Muul LM, Tuschong LM, Soenen SL, Jagadeesh GJ, Ramsey WJ, Long Z, Carter CS, Garabedian EK, Alleyne M, Brown M, Bernstein W, Schurman SH, Fleisher TA, Leitman SF, Dunbar CE, Blaese RM, Candotti F.

Blood. 2003 Apr 1;101(7):2563-9. Epub 2002 Nov 27.

12.

A novel approach using transcomplementing adenoviral vectors for gene therapy of adrenocortical cancer.

Wolkersdörfer GW, Bornstein SR, Higginbotham JN, Hiroi N, Vaquero JJ, Green MV, Blaese RM, Aguilera G, Chrousos GP, Ramsey WJ.

Horm Metab Res. 2002 Jun;34(6):279-87. Erratum in: Horm Metab Res. 2002 Oct;34(10):604..

PMID:
12173067
13.

Adenoviral vectors can impair adrenocortical steroidogenesis: clinical implications for natural infections and gene therapy.

Alesci S, Ramsey WJ, Bornstein SR, Chrousos GP, Hornsby PJ, Benvenga S, Trimarchi F, Ehrhart-Bornstein M.

Proc Natl Acad Sci U S A. 2002 May 28;99(11):7484-9.

14.
15.

AV.TK-mediated killing of subcutaneous tumors in situ results in effective immunization against established secondary intracranial tumor deposits.

Okada T, Shah M, Higginbotham JN, Li Q, Wildner O, Walbridge S, Oldfield E, Blaese RM, Ramsey WJ.

Gene Ther. 2001 Sep;8(17):1315-22.

16.

Advances in neurofibromatosis 2 (NF2): a workshop report.

Lim DJ, Rubenstein AE, Evans DG, Jacks T, Seizinger BG, Baser ME, Beebe D, Brackmann DE, Chiocca EA, Fehon RG, Giovannini M, Glazer R, Gusella JF, Gutmann DH, Korf B, Lieberman F, Martuza R, McClatchey AI, Parry DM, Pulst SM, Ramesh V, Ramsey WJ, Ratner N, Rutkowski JL, Ruttledge M, Weinstein DE.

J Neurogenet. 2000 Jun;14(2):63-106. Review. No abstract available.

PMID:
10992163
17.

Modified human immunodeficiency virus-based lentiviral vectors display decreased sensitivity to trans-dominant Rev.

Mautino MR, Ramsey WJ, Reiser J, Morgan RA.

Hum Gene Ther. 2000 Apr 10;11(6):895-908.

PMID:
10779166
18.
19.

Adeno-retroviral chimeric viruses as in vivo transducing agents.

Caplen NJ, Higginbotham JN, Scheel JR, Vahanian N, Yoshida Y, Hamada H, Blaese RM, Ramsey WJ.

Gene Ther. 1999 Mar;6(3):454-9.

20.

Adenoviral vectors capable of replication improve the efficacy of HSVtk/GCV suicide gene therapy of cancer.

Wildner O, Morris JC, Vahanian NN, Ford H Jr, Ramsey WJ, Blaese RM.

Gene Ther. 1999 Jan;6(1):57-62.

21.
22.

Amendment to Clinical Research Project. Project 90-C-195. April 1, 1993. Treatment of severe combined immunodeficiency disease (SCID) due to adenosine deaminase deficiency with autologous lymphocytes transduced with a human ADA gene.

Dunbar C, Chang L, Mullen C, Ramsey WJ, Carter C, Kohn D, Parkman R, Lenarsky C, Weinberg K, Wara D, Culver KW, Anderson WF, Leitman S, Fleisher T, Klein H, Shearer G, Clerici M, McGarrity G, Bastian J, Hershfield MS.

Hum Gene Ther. 1999 Feb 10;10(3):477-88. No abstract available.

PMID:
10048399
23.

The bystander effect in the HSVtk/ganciclovir system and its relationship to gap junctional communication.

Touraine RL, Ishii-Morita H, Ramsey WJ, Blaese RM.

Gene Ther. 1998 Dec;5(12):1705-11.

24.
25.

Generation of a conditionally neo(r)-containing retroviral producer cell line: effects of neo(r) on retroviral titer and transgene expression.

Wildner O, Candotti F, Krecko EG, Xanthopoulos KG, Ramsey WJ, Blaese RM.

Gene Ther. 1998 May;5(5):684-91.

26.

Adenovirus vectors as transcomplementing templates for the production of replication defective retroviral vectors.

Ramsey WJ, Caplen NJ, Li Q, Higginbotham JN, Shah M, Blaese RM.

Biochem Biophys Res Commun. 1998 May 29;246(3):912-9.

PMID:
9618311
27.

Efficient directional cloning of recombinant adenovirus vectors using DNA-protein complex.

Okada T, Ramsey WJ, Munir J, Wildner O, Blaese RM.

Nucleic Acids Res. 1998 Apr 15;26(8):1947-50.

29.

Gut epithelial cells as targets for gene therapy of hemophilia.

Lozier JN, Yankaskas JR, Ramsey WJ, Chen L, Berschneider H, Morgan RA.

Hum Gene Ther. 1997 Aug 10;8(12):1481-90.

PMID:
9287148
30.

T lymphocyte-directed gene therapy for ADA- SCID: initial trial results after 4 years.

Blaese RM, Culver KW, Miller AD, Carter CS, Fleisher T, Clerici M, Shearer G, Chang L, Chiang Y, Tolstoshev P, Greenblatt JJ, Rosenberg SA, Klein H, Berger M, Mullen CA, Ramsey WJ, Muul L, Morgan RA, Anderson WF.

Science. 1995 Oct 20;270(5235):475-80.

PMID:
7570001
31.

Retrovirus mediated gene transfer as therapy for adenosine deaminase (ADA) deficiency.

Ramsey WJ, Mullen CA, Blaese RM.

Leukemia. 1995 Oct;9 Suppl 1:S70.

PMID:
7475319
32.

Strategies for gene therapy.

Blaese RM, Mullen CA, Ramsey WJ.

Pathol Biol (Paris). 1993 Oct;41(8):672-6. Review.

PMID:
8290310
33.

Analysis of repetitive sequence elements containing tRNA-like sequences.

Lawrence CB, McDonnell DP, Ramsey WJ.

Nucleic Acids Res. 1985 Jun 25;13(12):4239-52.

34.
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