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Items: 41


Concentrations of oxidized linoleic acid derived lipid mediators in the amygdala and periaqueductal grey are reduced in a mouse model of chronic inflammatory pain.

Jensen JR, Pitcher MH, Yuan ZX, Ramsden CE, Domenichiello AF.

Prostaglandins Leukot Essent Fatty Acids. 2018 Aug;135:128-136. doi: 10.1016/j.plefa.2018.07.015. Epub 2018 Jul 23.


Oxidized linoleic acid metabolites induce liver mitochondrial dysfunction, apoptosis, and NLRP3 activation in mice.

Schuster S, Johnson CD, Hennebelle M, Holtmann T, Taha AY, Kirpich IA, Eguchi A, Ramsden CE, Papouchado BG, McClain CJ, Feldstein AE.

J Lipid Res. 2018 Sep;59(9):1597-1609. doi: 10.1194/jlr.M083741. Epub 2018 Jul 3.


Quantitation of Human Whole-Body Synthesis-Secretion Rates of Docosahexaenoic Acid and Eicosapentaenoate Acid from Circulating Unesterified α-Linolenic Acid at Steady State.

Lin YH, Hibbeln JR, Domenichiello AF, Ramsden CE, Salem NM, Chen CT, Jin H, Courville AB, Majchrzak-Hong SF, Rapoport SI, Bazinet RP, Miller BV 3rd.

Lipids. 2018 May;53(5):547-558. doi: 10.1002/lipd.12055. Epub 2018 Aug 3.


Lipidomic profiling of targeted oxylipins with ultra-performance liquid chromatography-tandem mass spectrometry.

Yuan ZX, Majchrzak-Hong S, Keyes GS, Iadarola MJ, Mannes AJ, Ramsden CE.

Anal Bioanal Chem. 2018 Sep;410(23):6009-6029. doi: 10.1007/s00216-018-1222-4. Epub 2018 Aug 3.


Effects of diets enriched in linoleic acid and its peroxidation products on brain fatty acids, oxylipins, and aldehydes in mice.

Ramsden CE, Hennebelle M, Schuster S, Keyes GS, Johnson CD, Kirpich IA, Dahlen JE, Horowitz MS, Zamora D, Feldstein AE, McClain CJ, Muhlhausler BS, Makrides M, Gibson RA, Taha AY.

Biochim Biophys Acta Mol Cell Biol Lipids. 2018 Oct;1863(10):1206-1213. doi: 10.1016/j.bbalip.2018.07.007. Epub 2018 Jul 25.


Bioactive Lipid Mediator Profiles in Human Psoriasis Skin and Blood.

Sorokin AV, Domenichiello AF, Dey AK, Yuan ZX, Goyal A, Rose SM, Playford MP, Ramsden CE, Mehta NN.

J Invest Dermatol. 2018 Jul;138(7):1518-1528. doi: 10.1016/j.jid.2018.02.003. Epub 2018 Feb 15.


A sixteen-week three-armed, randomized, controlled trial investigating clinical and biochemical effects of targeted alterations in dietary linoleic acid and n-3 EPA+DHA in adults with episodic migraine: Study protocol.

Mann JD, Faurot KR, MacIntosh B, Palsson OS, Suchindran CM, Gaylord SA, Lynch C, Johnston A, Maiden K, Barrow DA, Hibbeln JR, Ramsden CE.

Prostaglandins Leukot Essent Fatty Acids. 2018 Jan;128:41-52. doi: 10.1016/j.plefa.2017.11.002. Epub 2017 Nov 16.


A dose response study of the effect of prostaglandin E2 on thermal nociceptive sensitivity.

Domenichiello AF, Wilhite BC, Keyes GS, Ramsden CE.

Prostaglandins Leukot Essent Fatty Acids. 2017 Nov;126:20-24. doi: 10.1016/j.plefa.2017.08.015. Epub 2017 Aug 31.


Dietary Linoleic Acid and Its Oxidized Metabolites Exacerbate Liver Injury Caused by Ethanol via Induction of Hepatic Proinflammatory Response in Mice.

Warner DR, Liu H, Miller ME, Ramsden CE, Gao B, Feldstein AE, Schuster S, McClain CJ, Kirpich IA.

Am J Pathol. 2017 Oct;187(10):2232-2245. doi: 10.1016/j.ajpath.2017.06.008.


PURE study challenges the definition of a healthy diet: but key questions remain.

Ramsden CE, Domenichiello AF.

Lancet. 2017 Nov 4;390(10107):2018-2019. doi: 10.1016/S0140-6736(17)32241-9. Epub 2017 Aug 29. No abstract available.


A systems approach for discovering linoleic acid derivatives that potentially mediate pain and itch.

Ramsden CE, Domenichiello AF, Yuan ZX, Sapio MR, Keyes GS, Mishra SK, Gross JR, Majchrzak-Hong S, Zamora D, Horowitz MS, Davis JM, Sorokin AV, Dey A, LaPaglia DM, Wheeler JJ, Vasko MR, Mehta NN, Mannes AJ, Iadarola MJ.

Sci Signal. 2017 Aug 22;10(493). pii: eaal5241. doi: 10.1126/scisignal.aal5241.


RNA-Seq investigations of human post-mortem trigeminal ganglia.

LaPaglia DM, Sapio MR, Burbelo PD, Thierry-Mieg J, Thierry-Mieg D, Raithel SJ, Ramsden CE, Iadarola MJ, Mannes AJ.

Cephalalgia. 2018 Apr;38(5):912-932. doi: 10.1177/0333102417720216. Epub 2017 Jul 12.


Breathing Easier with Fish Oil - A New Approach to Preventing Asthma?

Ramsden CE.

N Engl J Med. 2016 Dec 29;375(26):2596-8. doi: 10.1056/NEJMe1611723. No abstract available.


Reconsidering Dietary Polyunsaturated Fatty Acids in Bipolar Disorder: A Translational Picture.

Saunders EF, Ramsden CE, Sherazy MS, Gelenberg AJ, Davis JM, Rapoport SI.

J Clin Psychiatry. 2016 Oct;77(10):e1342-e1347. doi: 10.4088/JCP.15com10431.


Omega-3 and Omega-6 Polyunsaturated Fatty Acids in Bipolar Disorder: A Review of Biomarker and Treatment Studies.

Saunders EF, Ramsden CE, Sherazy MS, Gelenberg AJ, Davis JM, Rapoport SI.

J Clin Psychiatry. 2016 Oct;77(10):e1301-e1308. doi: 10.4088/JCP.15r09925. Review.


Regulation of rat plasma and cerebral cortex oxylipin concentrations with increasing levels of dietary linoleic acid.

Taha AY, Hennebelle M, Yang J, Zamora D, Rapoport SI, Hammock BD, Ramsden CE.

Prostaglandins Leukot Essent Fatty Acids. 2018 Nov;138:71-80. doi: 10.1016/j.plefa.2016.05.004. Epub 2016 May 11.


Efficacy of omega-3 highly unsaturated fatty acids in the treatment of depression.

Hallahan B, Ryan T, Hibbeln JR, Murray IT, Glynn S, Ramsden CE, SanGiovanni JP, Davis JM.

Br J Psychiatry. 2016 Sep;209(3):192-201. doi: 10.1192/bjp.bp.114.160242. Epub 2016 Apr 21. Review.


Re-evaluation of the traditional diet-heart hypothesis: analysis of recovered data from Minnesota Coronary Experiment (1968-73).

Ramsden CE, Zamora D, Majchrzak-Hong S, Faurot KR, Broste SK, Frantz RP, Davis JM, Ringel A, Suchindran CM, Hibbeln JR.

BMJ. 2016 Apr 12;353:i1246. doi: 10.1136/bmj.i1246. Review.


Dietary linoleic acid-induced alterations in pro- and anti-nociceptive lipid autacoids: Implications for idiopathic pain syndromes?

Ramsden CE, Ringel A, Majchrzak-Hong SF, Yang J, Blanchard H, Zamora D, Loewke JD, Rapoport SI, Hibbeln JR, Davis JM, Hammock BD, Taha AY.

Mol Pain. 2016 Mar 10;12. pii: 1744806916636386. doi: 10.1177/1744806916636386. Print 2016.


Do antipsychotics cause hip fractures? Promise and pitfalls of big data.

Davis JM, Ramsden CE.

J Clin Psychiatry. 2015 Sep;76(9):e1155-6. doi: 10.4088/JCP.14com09551. No abstract available.


Diet-induced changes in n-3- and n-6-derived endocannabinoids and reductions in headache pain and psychological distress.

Ramsden CE, Zamora D, Makriyannis A, Wood JT, Mann JD, Faurot KR, MacIntosh BA, Majchrzak-Hong SF, Gross JR, Courville AB, Davis JM, Hibbeln JR.

J Pain. 2015 Aug;16(8):707-16. doi: 10.1016/j.jpain.2015.04.007. Epub 2015 May 7.


Targeted alterations in dietary n-3 and n-6 fatty acids improve life functioning and reduce psychological distress among patients with chronic headache: a secondary analysis of a randomized trial.

Ramsden CE, Faurot KR, Zamora D, Palsson OS, MacIntosh BA, Gaylord S, Taha AY, Rapoport SI, Hibbeln JR, Davis JM, Mann JD.

Pain. 2015 Apr;156(4):587-96. doi: 10.1097/01.j.pain.0000460348.84965.47.


The effect of modifying dietary LA and ALA intakes on omega-3 long chain polyunsaturated fatty acid (n-3 LCPUFA) status in human adults: a systematic review and commentary.

Wood KE, Mantzioris E, Gibson RA, Ramsden CE, Muhlhausler BS.

Prostaglandins Leukot Essent Fatty Acids. 2015 Apr;95:47-55. doi: 10.1016/j.plefa.2015.01.001. Epub 2015 Jan 19. Review.


Transient receptor potential vanilloid 1 gene deficiency ameliorates hepatic injury in a mouse model of chronic binge alcohol-induced alcoholic liver disease.

Liu H, Beier JI, Arteel GE, Ramsden CE, Feldstein AE, McClain CJ, Kirpich IA.

Am J Pathol. 2015 Jan;185(1):43-54. doi: 10.1016/j.ajpath.2014.09.007. Epub 2014 Oct 31.


Dietary omega-6 fatty acid lowering increases bioavailability of omega-3 polyunsaturated fatty acids in human plasma lipid pools.

Taha AY, Cheon Y, Faurot KF, Macintosh B, Majchrzak-Hong SF, Mann JD, Hibbeln JR, Ringel A, Ramsden CE.

Prostaglandins Leukot Essent Fatty Acids. 2014 May;90(5):151-7. doi: 10.1016/j.plefa.2014.02.003. Epub 2014 Feb 24.


A low omega-6 polyunsaturated fatty acid (n-6 PUFA) diet increases omega-3 (n-3) long chain PUFA status in plasma phospholipids in humans.

Wood KE, Lau A, Mantzioris E, Gibson RA, Ramsden CE, Muhlhausler BS.

Prostaglandins Leukot Essent Fatty Acids. 2014 Apr;90(4):133-8. doi: 10.1016/j.plefa.2013.12.010. Epub 2014 Jan 8.


Targeted alteration of dietary n-3 and n-6 fatty acids for the treatment of chronic headaches: a randomized trial.

Ramsden CE, Faurot KR, Zamora D, Suchindran CM, Macintosh BA, Gaylord S, Ringel A, Hibbeln JR, Feldstein AE, Mori TA, Barden A, Lynch C, Coble R, Mas E, Palsson O, Barrow DA, Mann JD.

Pain. 2013 Nov;154(11):2441-51. doi: 10.1016/j.pain.2013.07.028. Epub 2013 Jul 22.


Use of dietary linoleic acid for secondary prevention of coronary heart disease and death: evaluation of recovered data from the Sydney Diet Heart Study and updated meta-analysis.

Ramsden CE, Zamora D, Leelarthaepin B, Majchrzak-Hong SF, Faurot KR, Suchindran CM, Ringel A, Davis JM, Hibbeln JR.

BMJ. 2013 Feb 4;346:e8707. doi: 10.1136/bmj.e8707. Erratum in: BMJ. 2013;346:f903.


Low-n-6 and low-n-6 plus high-n-3 diets for use in clinical research.

MacIntosh BA, Ramsden CE, Faurot KR, Zamora D, Mangan M, Hibbeln JR, Mann JD.

Br J Nutr. 2013 Aug 28;110(3):559-68. doi: 10.1017/S0007114512005181. Epub 2013 Jan 18.


Identification and profiling of targeted oxidized linoleic acid metabolites in rat plasma by quadrupole time-of-flight mass spectrometry.

Yuan ZX, Rapoport SI, Soldin SJ, Remaley AT, Taha AY, Kellom M, Gu J, Sampson M, Ramsden CE.

Biomed Chromatogr. 2013 Apr;27(4):422-32. doi: 10.1002/bmc.2809. Epub 2012 Oct 5.


Lowering dietary linoleic acid reduces bioactive oxidized linoleic acid metabolites in humans.

Ramsden CE, Ringel A, Feldstein AE, Taha AY, MacIntosh BA, Hibbeln JR, Majchrzak-Hong SF, Faurot KR, Rapoport SI, Cheon Y, Chung YM, Berk M, Mann JD.

Prostaglandins Leukot Essent Fatty Acids. 2012 Oct-Nov;87(4-5):135-41. doi: 10.1016/j.plefa.2012.08.004. Epub 2012 Sep 5.


Fatty acids in cardiovascular health and disease: a comprehensive update.

Baum SJ, Kris-Etherton PM, Willett WC, Lichtenstein AH, Rudel LL, Maki KC, Whelan J, Ramsden CE, Block RC.

J Clin Lipidol. 2012 May-Jun;6(3):216-34. doi: 10.1016/j.jacl.2012.04.077. Epub 2012 Apr 13. Review.


All PUFAs are not created equal: absence of CHD benefit specific to linoleic acid in randomized controlled trials and prospective observational cohorts.

Ramsden CE, Hibbeln JR, Majchrzak-Hong SF.

World Rev Nutr Diet. 2011;102:30-43. doi: 10.1159/000327789. Epub 2011 Aug 5. No abstract available.


Don't disregard the essential distinction between PUFA species.

Ramsden CE, Hibbeln JR, Majchrzak-Hong SF, Davis JM.

Br J Nutr. 2011 Sep;106(6):953-7. Epub 2011 Jun 17. No abstract available.


Low omega-6 vs. low omega-6 plus high omega-3 dietary intervention for chronic daily headache: protocol for a randomized clinical trial.

Ramsden CE, Mann JD, Faurot KR, Lynch C, Imam ST, MacIntosh BA, Hibbeln JR, Loewke J, Smith S, Coble R, Suchindran C, Gaylord SA.

Trials. 2011 Apr 15;12:97. doi: 10.1186/1745-6215-12-97.


Changes in consumption of omega-3 and omega-6 fatty acids in the United States during the 20th century.

Blasbalg TL, Hibbeln JR, Ramsden CE, Majchrzak SF, Rawlings RR.

Am J Clin Nutr. 2011 May;93(5):950-62. doi: 10.3945/ajcn.110.006643. Epub 2011 Mar 2.


n-6 fatty acid-specific and mixed polyunsaturate dietary interventions have different effects on CHD risk: a meta-analysis of randomised controlled trials.

Ramsden CE, Hibbeln JR, Majchrzak SF, Davis JM.

Br J Nutr. 2010 Dec;104(11):1586-600. doi: 10.1017/S0007114510004010.


Dietary fat quality and coronary heart disease prevention: a unified theory based on evolutionary, historical, global, and modern perspectives.

Ramsden CE, Faurot KR, Carrera-Bastos P, Cordain L, De Lorgeril M, Sperling LS.

Curr Treat Options Cardiovasc Med. 2009 Aug;11(4):289-301.


Letter to the Editor re: Linoleic acid and coronary heart disease. Prostaglandins Leukot. Essent. Fatty Acids (2008), by W.S. Harris.

Ramsden CE, Hibbeln JR, Lands WE.

Prostaglandins Leukot Essent Fatty Acids. 2009 Jan;80(1):77; author reply 77-8. doi: 10.1016/j.plefa.2008.12.002. Epub 2009 Jan 14. No abstract available.


Pudendal nerve entrapment as source of intractable perineal pain.

Ramsden CE, McDaniel MC, Harmon RL, Renney KM, Faure A.

Am J Phys Med Rehabil. 2003 Jun;82(6):479-84. Review.


Re: Primary care and urology patients with the male pelvic pain syndrome: symptoms and quality of life.

Ramsden CE, McDaniel M.

J Urol. 2002 Nov;168(5):2134-5. No abstract available.


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