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Combination targeted therapy in chronic lymphocytic leukaemia - can pre-clinical studies translate to the clinic?

Ioannou N, Ramsay AG.

Br J Haematol. 2018 May 16. doi: 10.1111/bjh.15279. [Epub ahead of print] No abstract available.


Cocoa procyanidins modulate transcriptional pathways linked to inflammation and metabolism in human dendritic cells.

Midttun HLE, Ramsay A, Mueller-Harvey I, Williams AR.

Food Funct. 2018 May 23;9(5):2883-2890. doi: 10.1039/c8fo00387d.


miR-181c-BRK1 axis plays a key role in actin cytoskeleton-dependent T cell function.

Lim SP, Ioannou N, Ramsay AG, Darling D, Gäken J, Mufti GJ.

J Leukoc Biol. 2018 May;103(5):855-866. doi: 10.1002/JLB.1A0817-325RR. Epub 2018 Apr 14.


Matriptase-2 deficiency protects from obesity by modulating iron homeostasis.

Folgueras AR, Freitas-Rodríguez S, Ramsay AJ, Garabaya C, Rodríguez F, Velasco G, López-Otín C.

Nat Commun. 2018 Apr 10;9(1):1350. doi: 10.1038/s41467-018-03853-1.


Patient experience of centralized acute stroke care pathways.

Perry C, Papachristou I, Ramsay AIG, Boaden RJ, McKevitt C, Turner SJ, Wolfe CDA, Fulop NJ.

Health Expect. 2018 Mar 31. doi: 10.1111/hex.12685. [Epub ahead of print]


The potential role of cost-utility analysis in the decision to implement major system change in acute stroke services in metropolitan areas in England.

Hunter RM, Fulop NJ, Boaden RJ, McKevitt C, Perry C, Ramsay AIG, Rudd AG, Turner SJ, Tyrrell PJ, Wolfe CDA, Morris S.

Health Res Policy Syst. 2018 Mar 14;16(1):23. doi: 10.1186/s12961-018-0301-5.


Discrete-choice experiment to analyse preferences for centralizing specialist cancer surgery services.

Vallejo-Torres L, Melnychuk M, Vindrola-Padros C, Aitchison M, Clarke CS, Fulop NJ, Hines J, Levermore C, Maddineni SB, Perry C, Pritchard-Jones K, Ramsay AIG, Shackley DC, Morris S.

Br J Surg. 2018 Apr;105(5):587-596. doi: 10.1002/bjs.10761. Epub 2018 Mar 7.


Centralising specialist cancer surgery services in England: survey of factors that matter to patients and carers and health professionals.

Melnychuk M, Vindrola-Padros C, Aitchison M, Clarke CS, Fulop NJ, Levermore C, Maddineni SB, Moore CM, Mughal MM, Perry C, Pritchard-Jones K, Ramsay AIG, Shackley D, Vickers J, Morris S.

BMC Cancer. 2018 Feb 27;18(1):226. doi: 10.1186/s12885-018-4137-8.


Purple urine bag syndrome: a truly harmless sign?

Rooney H, Mokool L, Ramsay A, Nalagatla S.

Scott Med J. 2018 Jan 1:36933017743128. doi: 10.1177/0036933017743128. [Epub ahead of print]


Patient, carer and public involvement in major system change in acute stroke services: The construction of value.

McKevitt C, Ramsay AIG, Perry C, Turner SJ, Boaden R, Wolfe CDA, Fulop NJ.

Health Expect. 2018 Jun;21(3):685-692. doi: 10.1111/hex.12668. Epub 2018 Jan 18.


Predictive value of C-reactive protein for tuberculosis, bloodstream infection or death among HIV-infected individuals with chronic, non-specific symptoms and negative sputum smear microscopy.

Bedell RA, van Lettow M, Meaney C, Corbett EL, Chan AK, Heyderman RS, Anderson ST, Åkesson A, Kumwenda M, Zachariah R, Harries AD, Ramsay AR.

Trop Med Int Health. 2018 Mar;23(3):254-262. doi: 10.1111/tmi.13025. Epub 2018 Jan 4.


Inkjet-Printed Nanocavities on a Photonic Crystal Template.

Brossard FSF, Pecunia V, Ramsay AJ, Griffiths JP, Hugues M, Sirringhaus H.

Adv Mater. 2017 Dec;29(47). doi: 10.1002/adma.201704425. Epub 2017 Oct 24.


Spin Order and Phase Transitions in Chains of Polariton Condensates.

Ohadi H, Ramsay AJ, Sigurdsson H, Del Valle-Inclan Redondo Y, Tsintzos SI, Hatzopoulos Z, Liew TCH, Shelykh IA, Rubo YG, Savvidis PG, Baumberg JJ.

Phys Rev Lett. 2017 Aug 11;119(6):067401. doi: 10.1103/PhysRevLett.119.067401. Epub 2017 Aug 8.


Validation of smartphone step count algorithm used in STARFISH smartphone application.

Dybus A, Paul L, Wyke S, Brewster S, Gill JMR, Ramsay A, Campbell E.

Technol Health Care. 2017 Dec 4;25(6):1157-1162. doi: 10.3233/THC-170970.


Facile Purification of Milligram to Gram Quantities of Condensed Tannins According to Mean Degree of Polymerization and Flavan-3-ol Subunit Composition.

Brown RH, Mueller-Harvey I, Zeller WE, Reinhardt L, Stringano E, Gea A, Drake C, Ropiak HM, Fryganas C, Ramsay A, Hardcastle EE.

J Agric Food Chem. 2017 Sep 13;65(36):8072-8082. doi: 10.1021/acs.jafc.7b03489. Epub 2017 Sep 1.


New synthetic lipid antigens for rapid serological diagnosis of tuberculosis.

Jones A, Pitts M, Al Dulayymi JR, Gibbons J, Ramsay A, Goletti D, Gwenin CD, Baird MS.

PLoS One. 2017 Aug 14;12(8):e0181414. doi: 10.1371/journal.pone.0181414. eCollection 2017.


Activity of lenalidomide in mantle cell lymphoma can be explained by NK cell-mediated cytotoxicity.

Hagner PR, Chiu H, Ortiz M, Apollonio B, Wang M, Couto S, Waldman MF, Flynt E, Ramsay AG, Trotter M, Gandhi AK, Chopra R, Thakurta A.

Br J Haematol. 2017 Nov;179(3):399-409. doi: 10.1111/bjh.14866. Epub 2017 Aug 2.


Inertial displacement of a domain wall excited by ultra-short circularly polarized laser pulses.

Janda T, Roy PE, Otxoa RM, Šobáň Z, Ramsay A, Irvine AC, Trojanek F, Surýnek M, Campion RP, Gallagher BL, Němec P, Jungwirth T, Wunderlich J.

Nat Commun. 2017 May 17;8:15226. doi: 10.1038/ncomms15226.


Recurrent tuberculosis and associated factors: A five - year countrywide study in Uzbekistan.

Gadoev J, Asadov D, Harries AD, Parpieva N, Tayler-Smith K, Isaakidis P, Ali E, Hinderaker SG, Ogtay G, Ramsay A, Jalolov A, Dara M.

PLoS One. 2017 May 4;12(5):e0176473. doi: 10.1371/journal.pone.0176473. eCollection 2017.


Variant histology nodular lymphocyte predominant Hodgkin lymphoma - a route to transformation?

Szychot E, Shankar A, Haider A, Ramsay A.

Br J Haematol. 2018 May;181(3):403-406. doi: 10.1111/bjh.14607. Epub 2017 Apr 3. No abstract available.


School-based vaccination programmes: a systematic review of the evidence on organisation and delivery in high income countries.

Perman S, Turner S, Ramsay AI, Baim-Lance A, Utley M, Fulop NJ.

BMC Public Health. 2017 Mar 14;17(1):252. doi: 10.1186/s12889-017-4168-0. Review.


Advanced stage nodular lymphocyte predominant Hodgkin lymphoma in children and adolescents: clinical characteristics and treatment outcome - a report from the SFCE & CCLG groups.

Shankar AG, Roques G, Kirkwood AA, Lambilliotte A, Freund K, Leblanc T, Hayward J, Abbou S, Ramsay AD, Schmitt C, Gorde-Grosjean S, Pacquement H, Haouy S, Boudjemaa S, Aladjidi N, Hall GW, Landman-Parker J.

Br J Haematol. 2017 Apr;177(1):106-115. doi: 10.1111/bjh.14518. Epub 2017 Feb 21.


Identification of Structural Features of Condensed Tannins That Affect Protein Aggregation.

Ropiak HM, Lachmann P, Ramsay A, Green RJ, Mueller-Harvey I.

PLoS One. 2017 Jan 26;12(1):e0170768. doi: 10.1371/journal.pone.0170768. eCollection 2017.


B cell and antibody responses in mice induced by a putative cell surface peptidase of Pneumocystis murina protect against experimental infection.

Ruan S, Cai Y, Ramsay AJ, Welsh DA, Norris K, Shellito JE.

Vaccine. 2017 Jan 23;35(4):672-679. doi: 10.1016/j.vaccine.2016.11.073. Epub 2016 Dec 21.


Are patients with pulmonary tuberculosis who are identified through active case finding in the community different than those identified in healthcare facilities?

Abdurrahman ST, Lawson L, Blakiston M, Obasanya J, Yassin MA, Anderson RM, Oladimeji O, Ramsay A, Cuevas LE.

New Microbes New Infect. 2016 Nov 2;15:35-39. eCollection 2017 Jan.


Laser Microdissection and Spatiotemporal Pinoresinol-Lariciresinol Reductase Gene Expression Assign the Cell Layer-Specific Accumulation of Secoisolariciresinol Diglucoside in Flaxseed Coats.

Fang J, Ramsay A, Renouard S, Hano C, Lamblin F, Chabbert B, Mesnard F, Schneider B.

Front Plant Sci. 2016 Nov 21;7:1743. eCollection 2016.


Co-operative suppression of inflammatory responses in human dendritic cells by plant proanthocyanidins and products from the parasitic nematode Trichuris suis.

Williams AR, Klaver EJ, Laan LC, Ramsay A, Fryganas C, Difborg R, Kringel H, Reed JD, Mueller-Harvey I, Skov S, van Die I, Thamsborg SM.

Immunology. 2017 Mar;150(3):312-328. doi: 10.1111/imm.12687. Epub 2016 Nov 30.


Reorganising specialist cancer surgery for the twenty-first century: a mixed methods evaluation (RESPECT-21).

Fulop NJ, Ramsay AI, Vindrola-Padros C, Aitchison M, Boaden RJ, Brinton V, Clarke CS, Hines J, Hunter RM, Levermore C, Maddineni SB, Melnychuk M, Moore CM, Mughal MM, Perry C, Pritchard-Jones K, Shackley DC, Vickers J, Morris S.

Implement Sci. 2016 Nov 25;11(1):155.


Gene-based neonatal immune priming potentiates a mucosal adenoviral vaccine encoding mycobacterial Ag85B.

Dai G, Rady HF, Huang W, Shellito JE, Mason C, Ramsay AJ.

Vaccine. 2016 Dec 7;34(50):6267-6275. doi: 10.1016/j.vaccine.2016.10.065. Epub 2016 Nov 4.


Structure-Activity Relationship of Condensed Tannins and Synergism with trans-Cinnamaldehyde against Caenorhabditis elegans.

Ropiak HM, Desrues O, Williams AR, Ramsay A, Mueller-Harvey I, Thamsborg SM.

J Agric Food Chem. 2016 Nov 23;64(46):8795-8805. Epub 2016 Nov 14.


Triple-Resonant Brillouin Light Scattering in Magneto-Optical Cavities.

Haigh JA, Nunnenkamp A, Ramsay AJ, Ferguson AJ.

Phys Rev Lett. 2016 Sep 23;117(13):133602. Epub 2016 Sep 21.


Sustained research capacity after completing a Structured Operational Research and Training (SORT IT) course.

Guillerm N, Dar Berger S, Bissell K, Kumar AM, Ramsay A, Reid AJ, Zachariah R, Harries AD.

Public Health Action. 2016 Sep;6(3):207-208. Epub 2016 Sep 21. No abstract available.


Kinetics of the incorporation of the main phenolic compounds into the lignan macromolecule during flaxseed development.

Ramsay A, Fliniaux O, Quéro A, Molinié R, Demailly H, Hano C, Paetz C, Roscher A, Grand E, Kovensky J, Schneider B, Mesnard F.

Food Chem. 2017 Feb 15;217:1-8. doi: 10.1016/j.foodchem.2016.08.039. Epub 2016 Aug 16.


Building Global Capacity for Conducting Operational Research Using the SORT IT Model: Where and Who?

Zachariah R, Rust S, Berger SD, Guillerm N, Bissell K, Delaunois P, Reid AJ, Kumar AM, Olliaro PL, Reeder JC, Harries AD, Ramsay A.

PLoS One. 2016 Aug 9;11(8):e0160837. doi: 10.1371/journal.pone.0160837. eCollection 2016.


Explaining outcomes in major system change: a qualitative study of implementing centralised acute stroke services in two large metropolitan regions in England.

Fulop NJ, Ramsay AI, Perry C, Boaden RJ, McKevitt C, Rudd AG, Turner SJ, Tyrrell PJ, Wolfe CD, Morris S.

Implement Sci. 2016 Jun 3;11(1):80. doi: 10.1186/s13012-016-0445-z.


Phenotype and immune function of lymph node and peripheral blood CLL cells are linked to transendothelial migration.

Pasikowska M, Walsby E, Apollonio B, Cuthill K, Phillips E, Coulter E, Longhi MS, Ma Y, Yallop D, Barber LD, Patten P, Fegan C, Ramsay AG, Pepper C, Devereux S, Buggins AG.

Blood. 2016 Jul 28;128(4):563-73. doi: 10.1182/blood-2016-01-683128. Epub 2016 Jun 1.


Factors Underlying Ebola Virus Infection Among Health Workers, Kenema, Sierra Leone, 2014-2015.

Senga M, Pringle K, Ramsay A, Brett-Major DM, Fowler RA, French I, Vandi M, Sellu J, Pratt C, Saidu J, Shindo N, Bausch DG; Sierra Leone Kenema District Task Force and Kenema Government Hospital.

Clin Infect Dis. 2016 Aug 15;63(4):454-9. doi: 10.1093/cid/ciw327. Epub 2016 May 18.


Extracellular vesicles released by CD40/IL-4-stimulated CLL cells confer altered functional properties to CD4+ T cells.

Smallwood DT, Apollonio B, Willimott S, Lezina L, Alharthi A, Ambrose AR, De Rossi G, Ramsay AG, Wagner SD.

Blood. 2016 Jul 28;128(4):542-52. doi: 10.1182/blood-2015-11-682377. Epub 2016 Apr 26.


The need for operational research and capacity-building in support of the Global Technical Strategy for Malaria 2016-2030.

Ramsay A, Olliaro P, Reeder JC.

Malar J. 2016 Apr 25;15:235. doi: 10.1186/s12936-016-1302-x. No abstract available.


Increasing physical activity in stroke survivors using STARFISH, an interactive mobile phone application: a pilot study.

Paul L, Wyke S, Brewster S, Sattar N, Gill JM, Alexander G, Rafferty D, McFadyen AK, Ramsay A, Dybus A.

Top Stroke Rehabil. 2016 Jun;23(3):170-7. doi: 10.1080/10749357.2015.1122266. Epub 2016 Jan 8.


Patients direct costs to undergo TB diagnosis.

de Cuevas RM, Lawson L, Al-Sonboli N, Al-Aghbari N, Arbide I, Sherchand JB, Nnamdi EE, Aseffa A, Yassin MA, Abdurrahman ST, Obasanya J, Olanrewaju O, Datiko D, Theobald SJ, Ramsay A, Squire SB, Cuevas LE.

Infect Dis Poverty. 2016 Mar 24;5:24. doi: 10.1186/s40249-016-0117-x.


Mycobacterium tuberculosis whole genome sequencing and protein structure modelling provides insights into anti-tuberculosis drug resistance.

Phelan J, Coll F, McNerney R, Ascher DB, Pires DE, Furnham N, Coeck N, Hill-Cawthorne GA, Nair MB, Mallard K, Ramsay A, Campino S, Hibberd ML, Pain A, Rigouts L, Clark TG.

BMC Med. 2016 Mar 23;14:31. doi: 10.1186/s12916-016-0575-9.


Relapsed or poorly responsive nodular lymphocyte predominant Hodgkin lymphoma in children and adolescents - a report from the United Kingdom's Children's Cancer and Leukaemia Study Group.

Shankar AG, Kirkwood AA, Depani S, Bianchi E, Hayward J, Ramsay AD, Hall GW.

Br J Haematol. 2016 May;173(3):421-31. doi: 10.1111/bjh.13979. Epub 2016 Mar 21.


In Vivo Molecular Dissection of the Effects of HIV-1 in Active Tuberculosis.

Bell LC, Pollara G, Pascoe M, Tomlinson GS, Lehloenya RJ, Roe J, Meldau R, Miller RF, Ramsay A, Chain BM, Dheda K, Noursadeghi M.

PLoS Pathog. 2016 Mar 17;12(3):e1005469. doi: 10.1371/journal.ppat.1005469. eCollection 2016 Mar.


Oral Immunization of Mice with Live Pneumocystis murina Protects against Pneumocystis Pneumonia.

Samuelson DR, de la Rua NM, Charles TP, Ruan S, Taylor CM, Blanchard EE, Luo M, Ramsay AJ, Shellito JE, Welsh DA.

J Immunol. 2016 Mar 15;196(6):2655-65. doi: 10.4049/jimmunol.1502004. Epub 2016 Feb 10.


Flagellin Encoded in Gene-Based Vector Vaccines Is a Route-Dependent Immune Adjuvant.

Rady HF, Dai G, Huang W, Shellito JE, Ramsay AJ.

PLoS One. 2016 Feb 4;11(2):e0148701. doi: 10.1371/journal.pone.0148701. eCollection 2016.


Condensed tannins in extracts from European medicinal plants and herbal products.

Ropiak HM, Ramsay A, Mueller-Harvey I.

J Pharm Biomed Anal. 2016 Mar 20;121:225-231. doi: 10.1016/j.jpba.2015.12.034. Epub 2015 Dec 24.


Lessons for major system change: centralization of stroke services in two metropolitan areas of England.

Turner S, Ramsay A, Perry C, Boaden R, McKevitt C, Morris S, Pursani N, Rudd A, Tyrrell P, Wolfe C, Fulop N.

J Health Serv Res Policy. 2016 Jul;21(3):156-65. doi: 10.1177/1355819615626189. Epub 2016 Jan 24.


Nurse-like cells impact on disease progression in chronic lymphocytic leukemia.

Boissard F, Laurent C, Ramsay AG, Quillet-Mary A, Fournié JJ, Poupot M, Ysebaert L.

Blood Cancer J. 2016 Jan 15;6:e381. doi: 10.1038/bcj.2015.108. No abstract available.


Reporting guidelines for implementation and operational research.

Hales S, Lesher-Trevino A, Ford N, Maher D, Ramsay A, Tran N.

Bull World Health Organ. 2016 Jan 1;94(1):58-64. doi: 10.2471/BLT.15.167585. Epub 2015 Dec 2.

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