Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 83

1.

The human organic cation transporter OCT1 and its role as a target for drug responses.

Brosseau N, Ramotar D.

Drug Metab Rev. 2019 Sep 28:1-19. doi: 10.1080/03602532.2019.1670204. [Epub ahead of print]

PMID:
31564168
2.

Identification of essential yeast genes involved in polyamine resistance.

Aouida M, Ramotar D.

Gene. 2018 Nov 30;677:361-369. doi: 10.1016/j.gene.2018.08.066. Epub 2018 Aug 25. No abstract available.

PMID:
30153484
3.

UNG-1 and APN-1 are the major enzymes to efficiently repair 5-hydroxymethyluracil DNA lesions in C. elegans.

Papaluca A, Wagner JR, Saragovi HU, Ramotar D.

Sci Rep. 2018 May 1;8(1):6860. doi: 10.1038/s41598-018-25124-1.

4.

CUX1 stimulates APE1 enzymatic activity and increases the resistance of glioblastoma cells to the mono-alkylating agent temozolomide.

Kaur S, Ramdzan ZM, Guiot MC, Li L, Leduy L, Ramotar D, Sabri S, Abdulkarim B, Nepveu A.

Neuro Oncol. 2018 Mar 27;20(4):484-493. doi: 10.1093/neuonc/nox178.

5.

Uncharacterized ORF HUR1 influences the efficiency of non-homologous end-joining repair in Saccharomyces cerevisiae.

Omidi K, Jessulat M, Hooshyar M, Burnside D, Schoenrock A, Kazmirchuk T, Hajikarimlou M, Daniel M, Moteshareie H, Bhojoo U, Sanders M, Ramotar D, Dehne F, Samanfar B, Babu M, Golshani A.

Gene. 2018 Jan 10;639:128-136. doi: 10.1016/j.gene.2017.10.003. Epub 2017 Oct 5.

PMID:
28987344
6.

Structural modeling of human organic cation transporters.

Dakal TC, Kumar R, Ramotar D.

Comput Biol Chem. 2017 Jun;68:153-163. doi: 10.1016/j.compbiolchem.2017.03.007. Epub 2017 Mar 18.

PMID:
28343125
7.

Insights into a novel nuclear function for Fascin in the regulation of the amino-acid transporter SLC3A2.

Saad A, Bijian K, Qiu D, da Silva SD, Marques M, Chang CH, Nassour H, Ramotar D, Damaraju S, Mackey J, Bismar T, Witcher M, Alaoui-Jamali MA.

Sci Rep. 2016 Nov 7;6:36699. doi: 10.1038/srep36699.

9.

Peroxiredoxin 1 interacts with and blocks the redox factor APE1 from activating interleukin-8 expression.

Nassour H, Wang Z, Saad A, Papaluca A, Brosseau N, Affar el B, Alaoui-Jamali MA, Ramotar D.

Sci Rep. 2016 Jul 8;6:29389. doi: 10.1038/srep29389.

10.

The human organic cation transporter OCT1 mediates high affinity uptake of the anticancer drug daunorubicin.

Andreev E, Brosseau N, Carmona E, Mes-Masson AM, Ramotar D.

Sci Rep. 2016 Feb 10;6:20508. doi: 10.1038/srep20508.

11.

Complementation of the Yeast Model System Reveals that Caenorhabditis elegans OCT-1 Is a Functional Transporter of Anthracyclines.

Brosseau N, Andreev E, Ramotar D.

PLoS One. 2015 Jul 15;10(7):e0133182. doi: 10.1371/journal.pone.0133182. eCollection 2015.

12.

The long N-terminus of the C. elegans DNA repair enzyme APN-1 targets the protein to the nucleus of a heterologous system.

Wang Z, Yang X, Mazouzi A, Ramotar D.

Gene. 2014 Dec 15;553(2):151-7. doi: 10.1016/j.gene.2014.10.016. Epub 2014 Oct 13.

PMID:
25307766
13.

Functional variants of human APE1 rescue the DNA repair defects of the yeast AP endonuclease/3'-diesterase-deficient strain.

Wang Z, Ayoub E, Mazouzi A, Grin I, Ishchenko AA, Fan J, Yang X, Harihar T, Saparbaev M, Ramotar D.

DNA Repair (Amst). 2014 Oct;22:53-66. doi: 10.1016/j.dnarep.2014.07.010. Epub 2014 Aug 9.

PMID:
25108836
14.

Upregulation of the Saccharomyces cerevisiae efflux pump Tpo1 rescues an Imp2 transcription factor-deficient mutant from bleomycin toxicity.

Berra S, Ayachi S, Ramotar D.

Environ Mol Mutagen. 2014 Jul;55(6):518-24. doi: 10.1002/em.21865. Epub 2014 Mar 6.

PMID:
24599794
15.

Agp2, a member of the yeast amino acid permease family, positively regulates polyamine transport at the transcriptional level.

Aouida M, Rubio-Texeira M, Thevelein JM, Poulin R, Ramotar D.

PLoS One. 2013 Jun 3;8(6):e65717. doi: 10.1371/journal.pone.0065717. Print 2013. Erratum in: PLoS One. 2013;8(7). doi:10.1371/annotation/ff0ad3b6-fff4-4783-8c2e-968a95283ab8. Rubio Texeira, Marta [corrected to Rubio-Texeira, Marta].

16.

A functional autophagy pathway is required for rapamycin-induced degradation of the Sgs1 helicase in Saccharomyces cerevisiae.

Marrakchi R, Chouchani C, Poschmann J, Andreev E, Cherif M, Ramotar D.

Biochem Cell Biol. 2013 Jun;91(3):123-30. doi: 10.1139/bcb-2012-0084. Epub 2012 Dec 10.

PMID:
23668784
17.

Functional characterization of the Caenorhabditis elegans DNA repair enzyme APN-1.

Yang X, Fan J, Ishchenko AA, Patel D, Saparbaev MK, Ramotar D.

DNA Repair (Amst). 2012 Oct 1;11(10):811-22. doi: 10.1016/j.dnarep.2012.06.009. Epub 2012 Jul 20.

PMID:
22819077
18.

The peptidyl prolyl isomerase Rrd1 regulates the elongation of RNA polymerase II during transcriptional stresses.

Poschmann J, Drouin S, Jacques PE, El Fadili K, Newmarch M, Robert F, Ramotar D.

PLoS One. 2011;6(8):e23159. doi: 10.1371/journal.pone.0023159. Epub 2011 Aug 24.

19.

RNA polymerase II degradation in response to rapamycin is not mediated through ubiquitylation.

Jouvet N, Poschmann J, Douville J, Marrakchi R, Ramotar D.

Biochem Biophys Res Commun. 2011 Sep 23;413(2):248-53. doi: 10.1016/j.bbrc.2011.08.079. Epub 2011 Aug 23.

PMID:
21884683
20.

Functional analysis of OsPUT1, a rice polyamine uptake transporter.

Mulangi V, Phuntumart V, Aouida M, Ramotar D, Morris P.

Planta. 2012 Jan;235(1):1-11. doi: 10.1007/s00425-011-1486-9. Epub 2011 Jul 28.

PMID:
21796369
21.

The isomerase Rrd1 mediates rapid loss of the Sgs1 helicase in response to rapamycin.

Marrakchi R, Chouchani C, Cherif M, Boudabbous A, Ramotar D.

Biochem Cell Biol. 2011 Jun;89(3):332-40. doi: 10.1139/O11-006. Epub 2011 Jun 6.

PMID:
21639830
22.

Rrd1 isomerizes RNA polymerase II in response to rapamycin.

Jouvet N, Poschmann J, Douville J, Bulet L, Ramotar D.

BMC Mol Biol. 2010 Dec 3;11:92. doi: 10.1186/1471-2199-11-92.

23.

A new twist in cellular resistance to the anticancer drug bleomycin-A5.

Aouida M, Ramotar D.

Curr Drug Metab. 2010 Sep;11(7):595-602. Review.

PMID:
20812903
24.

The endonuclease IV family of apurinic/apyrimidinic endonucleases.

Daley JM, Zakaria C, Ramotar D.

Mutat Res. 2010 Dec;705(3):217-27. doi: 10.1016/j.mrrev.2010.07.003. Epub 2010 Aug 3. Review.

PMID:
20667510
25.

Internalization of a thiazole-modified peptide in Sinorhizobium meliloti occurs by BacA-dependent and -independent mechanisms.

Wehmeier S, Arnold MF, Marlow VL, Aouida M, Myka KK, Fletcher V, Benincasa M, Scocchi M, Ramotar D, Ferguson GP.

Microbiology. 2010 Sep;156(Pt 9):2702-13. doi: 10.1099/mic.0.039909-0. Epub 2010 May 27.

PMID:
20507886
26.

Genetic interactions between HNT3/Aprataxin and RAD27/FEN1 suggest parallel pathways for 5' end processing during base excision repair.

Daley JM, Wilson TE, Ramotar D.

DNA Repair (Amst). 2010 Jun 4;9(6):690-9. doi: 10.1016/j.dnarep.2010.03.006. Epub 2010 Apr 15.

27.

The human carnitine transporter SLC22A16 mediates high affinity uptake of the anticancer polyamine analogue bleomycin-A5.

Aouida M, Poulin R, Ramotar D.

J Biol Chem. 2010 Feb 26;285(9):6275-84. doi: 10.1074/jbc.M109.046151. Epub 2009 Dec 25.

28.

Caenorhabditis elegans APN-1 plays a vital role in maintaining genome stability.

Zakaria C, Kassahun H, Yang X, Labbé JC, Nilsen H, Ramotar D.

DNA Repair (Amst). 2010 Feb 4;9(2):169-76. doi: 10.1016/j.dnarep.2009.11.007. Epub 2009 Dec 24.

PMID:
20036200
29.

Novel role for the Saccharomyces cerevisiae oligopeptide transporter Opt2 in drug detoxification.

Aouida M, Khodami-Pour A, Ramotar D.

Biochem Cell Biol. 2009 Aug;87(4):653-61. doi: 10.1139/o09-045.

PMID:
19767828
30.

Human glyceraldehyde-3-phosphate dehydrogenase plays a direct role in reactivating oxidized forms of the DNA repair enzyme APE1.

Azam S, Jouvet N, Jilani A, Vongsamphanh R, Yang X, Yang S, Ramotar D.

J Biol Chem. 2008 Nov 7;283(45):30632-41. doi: 10.1074/jbc.M801401200. Epub 2008 Sep 5.

31.

Overexpression of the cis/trans isomerase PTPA triggers caspase 3-dependent apoptosis.

Azam S, Drobetsky E, Ramotar D.

Apoptosis. 2007 Jul;12(7):1243-55.

PMID:
17333320
32.

Functional and genetic analysis of the Saccharomyces cerevisiae RNC1/TRM2: evidences for its involvement in DNA double-strand break repair.

Choudhury SA, Asefa B, Webb A, Ramotar D, Chow TY.

Mol Cell Biochem. 2007 Jun;300(1-2):215-26. Epub 2007 Jan 5.

PMID:
17205207
33.

Deletion of the chromatin remodeling gene SPT10 sensitizes yeast cells to a subclass of DNA-damaging agents.

Tounekti K, Aouida M, Leduc A, Poschmann J, Yang X, Belhadj O, Ramotar D.

Environ Mol Mutagen. 2006 Dec;47(9):707-17.

PMID:
17078097
34.

The Saccharomyces cerevisiae phosphatase activator RRD1 is required to modulate gene expression in response to rapamycin exposure.

Douville J, David J, Lemieux KM, Gaudreau L, Ramotar D.

Genetics. 2006 Feb;172(2):1369-72. Epub 2005 Dec 1.

35.

Saccharomyces cerevisiae Ogg1 prevents poly(GT) tract instability in the mitochondrial genome.

Vongsamphanh R, Wagner JR, Ramotar D.

DNA Repair (Amst). 2006 Feb 3;5(2):235-42. Epub 2005 Nov 15.

PMID:
16293446
36.
37.
38.

Identification of two apurinic/apyrimidinic endonucleases from Caenorhabditis elegans by cross-species complementation.

Shatilla A, Leduc A, Yang X, Ramotar D.

DNA Repair (Amst). 2005 Jun 8;4(6):655-70. Epub 2005 Apr 12.

PMID:
15907773
39.

AGP2 encodes the major permease for high affinity polyamine import in Saccharomyces cerevisiae.

Aouida M, Leduc A, Poulin R, Ramotar D.

J Biol Chem. 2005 Jun 24;280(25):24267-76. Epub 2005 Apr 26.

40.

Alpha-anomeric deoxynucleotides, anoxic products of ionizing radiation, are substrates for the endonuclease IV-type AP endonucleases.

Ishchenko AA, Ide H, Ramotar D, Nevinsky G, Saparbaev M.

Biochemistry. 2004 Dec 7;43(48):15210-6.

PMID:
15568813
41.
42.
43.

Isolation and characterization of Saccharomyces cerevisiae mutants with enhanced resistance to the anticancer drug bleomycin.

Aouida M, Tounekti O, Leduc A, Belhadj O, Mir L, Ramotar D.

Curr Genet. 2004 May;45(5):265-72. Epub 2004 Mar 9.

PMID:
15007625
44.

Transcriptional activation of metalloid tolerance genes in Saccharomyces cerevisiae requires the AP-1-like proteins Yap1p and Yap8p.

Wysocki R, Fortier PK, Maciaszczyk E, Thorsen M, Leduc A, Odhagen A, Owsianik G, Ulaszewski S, Ramotar D, Tamás MJ.

Mol Biol Cell. 2004 May;15(5):2049-60. Epub 2004 Feb 20.

45.
46.

The role of yeast DNA 3'-phosphatase Tpp1 and rad1/Rad10 endonuclease in processing spontaneous and induced base lesions.

Karumbati AS, Deshpande RA, Jilani A, Vance JR, Ramotar D, Wilson TE.

J Biol Chem. 2003 Aug 15;278(33):31434-43. Epub 2003 Jun 3.

47.

Characterization of two independent amino acid substitutions that disrupt the DNA repair functions of the yeast Apn1.

Jilani A, Vongsamphanh R, Leduc A, Gros L, Saparbaev M, Ramotar D.

Biochemistry. 2003 Jun 3;42(21):6436-45.

PMID:
12767225
48.

Disruption of the Saccharomyces cerevisiae cell-wall pathway gene SLG1 causes hypersensitivity to the antitumor drug bleomycin.

Leduc A, He CH, Ramotar D.

Mol Genet Genomics. 2003 Apr;269(1):78-89. Epub 2003 Feb 12.

PMID:
12715156
49.

Protective mechanisms against the antitumor agent bleomycin: lessons from Saccharomyces cerevisiae.

Ramotar D, Wang H.

Curr Genet. 2003 Jul;43(4):213-24. Epub 2003 Apr 16. Review.

PMID:
12698269
50.

Supplemental Content

Loading ...
Support Center